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62 articles for “conjugates”
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Aceclofenac and Diclofenac Sodium Conjugates with Amino Acids to Overcome Acidity
Abstract: This research work was based on a conjugate approach with some non-steroidal anti-inflammatory drugs (NSAIDs) to overcome the side effects like gastric irritation, solubility behavior, and some other effects of NSAIDs. Almost all the NSAIDs have undesirable reactions as well as they cause some types of major adverse reactions. Here the prodrugs conjugates are the approaches that increase the lipophilicity of the drug and decrease the solubility in water by …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 12, Issue 2, 2022 · pp. 19–25 Read article
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Estimation of Heat Transfer Rate with Conjugate Gradient Method
Abstract: In thermal system, a considerable amount of heat leftovers with the exhaust flue gases. Appropriate arrangement to recover this waste heat may contribute to the enhancement of overall utilization of the energy supplied to the thermal system. In this study, heat transfer rate is approximately determined using inverse heat transfer concept. Simulated temperature readings have been taken at the measurement location on the mild steel rod. Conjugate gradient method (CGM) …
Published in Journal of Experimental & Applied Mechanics · Vol. 9, Issue 1, 2018 · pp. 1–8 Read article
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Chlorophyll-Mimicking Ti₃C₂Tₓ MXene-Conjugated Polymer Nanocomposites: Nature-Inspired Exciton Funneling Architecture for Ultrahigh Photon-to-Electron Conversion in Organic Solar Cells
Abstract: Green plant photosynthetic machinery is one of the most efficient natural systems for harvesting solar energy and converting it into useable electronic charge. Specifically, chlorophyll molecules in the Light-Harvesting Complex II (LHC-II) achieve nearly unity quantum yield via a well-organized Förster Resonance Energy Transfer (FRET) mechanism that enables excitons to migrate towards reaction centers. This study presents a bio-inspired nanocomposite architecture using two-dimensional Ti₃C₂Tₓ MXene nanosheets functionalized with chlorophyll-mimicking porphyrin …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 114–130 Read article
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Lipid Drug Conjugates: A Novel Approach for Drug Delivery A Systematic Review
Abstract: The lipid drug conjugates (LDCS) a novel lipid based nanoparticles which has been extensively employed for the delivery and targeting of drugs. These have been exploited for many features in the field of pharmaceutical technology. The lipid drug conjugates have a 33% drug loading capacity more than the solid lipid nanoparticles (SLNs). The lipid drug conjugates have the potential to act as a delivery system for hydrophilic and lipophilic drugs, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 3, Issue 3, 2012 · pp. 1–8 Read article
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Synthesis and Synergistic Effects of Ciprofloxacin Conjugated Zinc Oxide Nanoparticles
Abstract: Zinc oxide nanoparticles (ZnO NPs) are known as a multifunctional material because of its unique physical and chemical properties. The result of zinc oxide nano powder was characterized using various analytical techniques, such as UV-Vis spectroscopy, Fourier Transform Infra-Red (FTIR), Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM) and X-Ray Diffraction (XRD) patterns. Synthesized zinc oxide nano powder was stored in dried form in the room temperature for further study. …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 9, Issue 1, 2019 · pp. 61–71 Read article
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Production of Poly Hydroxybutyrate from Bacillus megaterium and its Conjugation with Nanoparticles to Determine the Antibacterial Activity
Abstract: Plastics have become an important part of modern life and are used in different sectors of operations like packaging, building materials, consumer products etc. Presently plastics and synthetic polymers are mainly produced by using the petrochemical material that cannot be decomposed easily. Thus they contribute to the environmental pollution. The increased cost of solid waste disposal as well as the potential hazards from incineration of wastes makes synthetic plastic waste …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 1, Issue 1, 2011 · pp. 126–132 Read article
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Synthesis and study of Bio-conjugated graphene
Abstract: Currently many research organizations are studying on graphene and its structure. The poor dispersion quality of graphene has been reported by many researchers. It is a disadvantage of graphene to improve its dispersion quality carboxylation of graphene is necessary (attaching carbon species on the edges and the basal plane of garphene).It also helps for further attachment. It may reduce the conductivity but it improves the dispersion quality. Carboxylic graphene can …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 3, Issue 3, 2013 · pp. 21–26 Read article
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Molecular Docking Study of Curcumin-Sugar Conjugates as Cholesterol Biosynthesis as well as Staphylococcus Aureus Virulence Inhibitor
Abstract: Methicillin resistant Staphylococcus Aureus infections are the major concern in both, communities as well as in clinics. Presqualene diphosphate is the key molecule obtained from farnesyl diphosphate for the biosynthesis of staphylophyloxanthin which is responsible for the virulence of Staphylococcus Aureus as well as for cholesterol biosynthesis in humans. We designed some natural curcumin-sugar conjugates that binds to the protein associated with the formation of presqualene diphosphate and inhibit it, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 4, Issue 1, 2017 · pp. 15–21 Read article
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Cis-9, Trans-11 Conjugated Linoleic Acid in Milk: Natural Sources, Nutritional Advantages, and Potential Health Benefits
Abstract: Cis-9, trans-11 conjugated linoleic acid (CLA) is the most common type of CLA found in milk. It has gained a lot of attention because it may have several health benefits. This bioactive lipid is primarily derived from ruminal biohydrogenation of dietary linoleic acid and endogenous synthesis in the mammary gland via Δ9-desaturase activity. Various dietary and management strategies influence CLA concentrations in milk, including forage composition, lipid supplementation, and grazing …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
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Green Synthesis and Characterization of Silver Nano-conjugates Using Heliotropium indicum and Glycosmis pentaphylla Leaf Aqueous Extracts
Abstract: Heliotropium indicum Linn. (Family Boraginaceae), an annual herbaceous medicinal plant, is usually known as Indian heliotrope. Glycosmis pentaphylla (Retz.) DC (Family Rutaceae) is a perennial shrub, commonly known as orange-berry. These traditionally used medicinal plants originate from tropical and temperate parts of the world along with India, Southeast Asia, Northern Australia, and some other African countries. Extensive literature studies suggested that the different parts of the plant are reported to …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 9, Issue 2, 2019 · pp. 22–30 Read article
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In Silico Study of Curcumin-Sugar Conjugates as Dual Inhibitors on Both COX-1 and COX-2 Enzymes for the Discovery of Anti-inflammatory Agents
Abstract: Curcumin is a polyphenolic compound well known for its anti-inflammatory properties. The aim of the study was to design some novel curcumin derivatives that are water soluble as well as good anti-inflammatory agents with fewer side effects. In silico study was performed on the proteins by using three softwares iGEMDOCK, AutoDOCK, AutoDOCKVina as dual inhibitors for both COX-1 and COX-2. The result gives us theoretical contribution for understanding the ligand-protein …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 4, Issue 1, 2017 · pp. 25–30 Read article
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Laser Ablation Technique to Synthesize Ag Nanoparticles in Harsh Environment During Conjugation with Ovalbumin and Their Effects on Candida albicans
Abstract: In this study was developed a rapid, easy, eco-friendly and free-polutions method to AgNPs synthesized which was laser ablation technique to bulk target silver in harsh environment which was SBF due to salts and ions content cause silver nanoparticle aggregated via the interactions among nanoparticles and components of the ionic solution. So, was add ovalbumin to achived long term stability of colloidal AgNPs solution because of this protien has been …
Published in Journal of Polymer & Composites · Vol. 11, Issue 2, 2023 · pp. 47–60 Read article
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A Review on Deviation Function Method
Abstract: This review paper covers the method to develop a lobe rotor pair profile used in many mechanical mechanisms. Lobe rotor pairs are conjugate generated pairs. It means that for each lobe there exists a corresponding another lobe such that for each point on first lobe there is a point on another lobe having same velocity. Deviation function method is widely used to develop a lobe profile. Deviation function method is …
Published in Trends in Mechanical Engineering & Technology · Vol. 5, Issue 2, 2015 · pp. 28–33 Read article
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Chitosan-conjugated GnRH Nanoparticles with AFM Appearance
Abstract: Nanotechnology can provide new tools for molecular and cellular biology, biotechnology, veterinary physiology, reproduction, detection of pathogens and many more. There are several areas such as science, engineering of agriculture, animal and food systems where nanotechnology could be applied. Application of nanotechnology can be employed in the development of sustained release systems of molecules such as hormones, vitamins, antibiotics, antioxidants and nucleic acids. Longer lasting surges in Gonadotropin hormone (GtH) …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 8, Issue 3, 2019 · pp. 3–5 Read article
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Monoclonal antibodies in targeted cancer therapy advances, resistance mechanisms, and next-gen formats (Bispesifics, ADCs)
Abstract: Breast cancer is one of the leading causes of cancer-related morbidity and death worldwide, which emphasizes the need for more effective and focused treatment strategies. antibody-mediated drug delivery techniques. Specifically, antibody–drug conjugates (ADCs) have emerged as a potential approach that combines the specificity of monoclonal antibodies with the potent cytotoxicity of anticancer drugs. By selectively targeting tumor-associated antigens, ADCs enhance drug accumulation within cancer cells while minimizing systemic toxicity associated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 · pp. 62–79 Read article
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Non-Small Cell Lung Cancer: Types, Pathogenesis, Diagnosis, and Novel Therapeutic Strategies
Abstract: Non-small cell lung cancer (NSCLC) is the most prevalent type of lung cancer, accounting for over 85% of all cases globally. It remains one of the primary causes of cancer-related death due to its rapid progression, few early symptoms, and late detection. The three main forms of non-small cell lung cancer (NSCLC) are adenocarcinoma, squamous cell carcinoma, and giant cell carcinoma; each has a unique histology, prognosis, and response to …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 · pp. 07–22 Read article
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Investigation to Enhance Performance of Finned U-Tube Shell-and-Tube Heat Exchangers Using Epoxy Based Polymer Composite Material
Abstract: Shell-and-tube heat exchangers remain indispensable in thermal engineering systems; however, conventional metallic configurations often face challenges related to corrosion, weight, and limited thermal optimization. In this study, a novel approach is proposed by integrating epoxy-based polymer composite materials with finned U-tube geometries to enhance thermo-hydraulic performance while addressing material limitations of traditional systems. The work focuses on the development and evaluation of a hybrid heat exchanger comprising a mild steel …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 618–633 Read article
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Thermo-hydraulic Performance of Multi-Pass Double-Pipe Heat Exchangers: Integrating Polymer Composite Tube Wall Materials via CFD Parametric Study and Experimental Validation
Abstract: Metallic materials such as steel and copper have traditionally dominated heat exchanger manufacturing because of their excellent thermal conductivity, mechanical strength, and long-established industrial reliability. However, their high weight, susceptibility to corrosion in aggressive operating environments, and inability to provide tunable thermal properties have motivated interest in alternative materials for next-generation thermal systems. Thermally conductive polymer composites reinforced with graphene nanoplatelets (GNP), boron nitride (BN), and carbon-based fillers offer an …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article
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A Method of Universal Primer Design for The Detection of Diverged CTX-M Beta-Lactamases in Multi-Drug Resistant Superbugs
Abstract: Complexity of many diverged β-lactamases in common multi-drug resistant bacteria has reached very high level. We found >40% of common bacteria in Kolkata water bodies were ampicillin resistant and reported clinical isolates were >95% ampicillin resistant worldwide. More than twenty unique sequence classes of β-lactamases were known to cause MDR inactivating penicillin, cephalosporin and carbapenem drugs. Further, there are other diverged MDR genes like drug efflux genes (acrAB, mexAB-EF, tetA), …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 9, Issue 2, 2019 · pp. 1–10 Read article
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Milk Fat and its Role in Human Health
Abstract: Milk fat, a variable component influenced by dairy cattle diets, plays crucial roles in the body as an insulator, energy source, and transporter of fat-soluble vitamins. Understanding its composition and impact on health is essential, given its complexity and interaction with dietary fats. Lipids, including essential fatty acids, contribute to bodily functions and influence eicosanoid production. The introduction of supplemental fats can alter fatty acid synthesis, affecting health outcomes. Conjugated …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 12, Issue 3, 2023 · pp. 1–6 Read article