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25 articles for “cirrhosis”
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An Insight to Hyponatremia in Cirrhosis: Pathophysiology and Management Approaches
Abstract: Cirrhosis is considered by systemic and splanchnic vasodilation that principals to extreme nonosmotic excretion of vasopressin. Hyponatremia is a mutual electrolyte irregularity in progressive liver disease that outcomes from the diminished capability of the kidney to excrete solute-free water that principals to “dilutional” hyponatremia water retention uneven to the retaining of sodium. Hyponatremia is mutual in cirrhosis. It frequently happens in a progressive phase of the disease and is related …
Published in Research and Reviews : A Journal of Immunology · Vol. 10, Issue 3, 2020 · pp. 30–46 Read article
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A Possible Case of Methotrexate Induced Hepatic Cirrhosis
Abstract: A patient with psoriasis on long term methotrexate (MTX) therapy (cumulative dose=14.4 g) developed cirrhosis of liver associated with portal HTN and ascites. All the other possible causes for liver cirrhosis like HBV, HCV infection were ruled out. Investigations: antibodies (LKM-1), anti-mitochondrial antibodies (AMA 1,2,3,4,5,6,7,8,9), anti-treponemal antibody (TPHA), HBS Ag, anti-HCV were negative
Published in Research and Reviews: A Journal of Pharmacology · Vol. 3, Issue 1, 2013 Read article
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Lymph Purification for Liver Cirrhosis Patients’ Treatment
Abstract: The existing methods of lymph purification do not permit to clean the organism of patient with liver cirrhosis from an increased concentration of toxic substances contained in his lymph. In addition, the process of cleaning of the lymph in these methods takes a long time, during which the patient remains without lymph, waiting for clean lymph that sharply weakens him and in extraordinary cases can lead to death. The presence …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 1, 2020 · pp. 11–17 Read article
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Combination Therapy with Propranolol and Cephalanoplos Segetum Against First Variceal Hemorrhage in Patients with Cirrhosis
Abstract: Background: Primary prophylaxis aims to prevent variceal hemorrhage in patients with esophageal varices who do not have a history of hemorrhage. The use of nonselective beta blockers is the first option for primary prophylaxis to prevent variceal bleeding in patients with the cirrhosis. Application of non-selective beta blocker has various kinds of merits, but patient's endurance to beta blocker becomes a problem and it does not prevent primary variceal bleeding …
Published in Research and Reviews: A Journal of Medicine · Vol. 12, Issue 1, 2022 · pp. 17–22 Read article
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Two-chamber Medical Electroflotator for Cleaning of the Lymph of Cancer Patients from Toxic Substances and for the Destruction and Removal of Cancer Cells Contained in It
Abstract: Existing devices for cleaning of the lymph of patients with liver cirrhosis or hepatitis from a high concentration of toxic substances, contained in it, do not allow cleaning the body of patients from these toxic substances. In addition, these devices require the patient's lymph to be purified in a discrete mode, i.e., all the patient's lymph, without which the patient remains, is purified for a sufficiently long time, and after …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 1, 2022 · pp. 21–27 Read article
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Aetiology of Ascites and Diagnostic Value of Ascitic Fluid Analysis
Abstract: Ascites is an important feature of many diseases, mainly liver disorder. The aim of this study is to determine the causes of ascites in Nagpur region, and to evaluate the significance of ascitic fluid analysis in different types of ascites.This prospective study was conducted at Govt. Medical College Nagpur. It involved patients admitted with primary diagnosis of ascites, over a period of 1 year, (may 2007-may 2008). The total number …
Published in Research and Reviews: A Journal of Medicine · Vol. 1, Issue 1, 2011 Read article
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The Toxic Substances and Cancer Cells Lymphosorption using Hydrogen and Oxygen Bubbles Photoelectroflotation Process Powered by Light Energy
Abstract: This study presents the application of a new developed method of hydrogen and oxygen bubbles photoelectroflotation and a specially developed complex: photoelectrolyzer + bicameral flotation cell for cleaning of the lymph of a patient with liver cirrhosis or hepatitis from toxic substances and for destroying and removing cancer cells contained in it, by adhesion of microdispersed negatively charged hydrogen bubbles, formed in the photoelectrolyzer during the arising photoelectrolysis of water, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 12, Issue 1, 2023 · pp. 6–20 Read article
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Evaluation of Some of the Antibiotics in the Management of Hepatic Encephalopathy (HE): An Overview
Abstract: Hepatic encephalopathy (HE) is a common complication among patients with liver cirrhosis associated with a high mortality rate. It is marked by fluctuating neuropsychiatric and cognitive impairment, which can be severe and life threatening. Liver cirrhosis is a leading cause of morbidity and mortality worldwide but exact prevalence of cirrhosis is not known. Prevalence of HE, also known as portosystemic encephalopathy (PSE), is 24% in cirrhotic patients. The diagnosis remains …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 10, Issue 3, 2020 · pp. 22–39 Read article
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The Epidemiology of Risk Factors and Complications of Non-Alcoholic Fatty Liver Disease (NAFLD)
Abstract: AbstractIn most of the developed countries non alcoholic fatty liver disease (NAFLD) is the common chronic lover disease mainly due to obesity. The disease increases liver related morbidity and mortality, and often increases the risk for other comorbidities, such as type 2 daibetes and cardiovascular disease. In NAFLD cardiovascular diseases are the major causes of death and only some people develop fibrosis and liver related complications. The prevalence of non …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 13, Issue 3, 2022 · pp. 9–13 Read article
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An Insight to Diagnosis and Management of Druginduced Hepatotoxicity: An Overview
Abstract: (ADRs) Adverse Drug Reactions are constitute and mutual chief health problem. Throughout the last period liver toxicity has remained one of the most recurrent reasons for pharmacovigilance protection intelligences and the withdrawal from the marketplace of an accepted medicinal product. Liver is a main organ elaborate in the systemic deposition and decontamination of exogenous and endogenous ingredients. Liver disfunction challenges not only health care specialists but also the pharmaceutical manufacturing …
Published in Trends in Drug Delivery · Vol. 8, Issue 2, 2023 · pp. 39–54 Read article
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The Evaluation of the Light Parameters and Pleural Fluid Cholesterol to Determine the Differences Between Exudative and Transudative Pleural Discharge
Abstract: Background: Pleural effusion occurs when an imbalance between pleural fluid production and absorption leads to the accumulation of excess fluid in the pleural cavity. Pleural effusions are commonly classified into two types: transudative or exudative, depending on the underlying mechanism of fluid formation. While transudates typically result from systemic factors like heart failure or liver cirrhosis, exudates are usually caused by local factors such as infection, malignancy, or inflammation. Differentiating …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 30–35 Read article
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The Role of Pyruvate Dehydrogenase in Non-Alcoholic Fatty Liver Disease: Therapeutic Insights and Future Directions
Abstract: Non-alcoholic fatty liver disorders (NAFLD) are defined by the accumulation of excess fat in the liver that has no other cause, such as drinking alcohol. Pyruvate dehydrogenase has been established as an alternative treatment for this disorder. NAFLD pathogenesis is complex and includes oxidative stress inflammatory processes and mitochondrial dysfunction. Impaired liver fatty acid oxidation and glucose oxidation are significant individuals in developing NAFLD, and strategies to reverse these defects …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 44–51 Read article
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In Silico Screening of Terminalia chebula Phytocompounds as Potential Inhibitors of NTCP and DDB1 in Hepatitis B Virus Infection
Abstract: Hepatitis B virus (HBV) infection is a major global health concern, and chronic carriers are at risk of developing cirrhosis, hepatocellular carcinoma (HCC), and even death. Existing treatments can effectively inhibit viral replication, but they achieve little eradication of the virus because of covalently closed circular DNA (cccDNA) retention. In this investigation, bioactive compounds of Terminalia chebula, a plant known for its hepatoprotective and antiviral properties in traditional medicine, were …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 33–44 Read article
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Comprehensive Study and Triggering Factors of Alcoholic and Non-Alcoholic Fatty Liver
Abstract: Over the past few years, fatty liver disease has turned out to be a rather widespread phenomenon and has become a serious issue with the global population nowadays. It comprises alcoholic fatty liver disease and non-alcoholic fatty liver disease, which develop under the influence of various initiating factors, though frequently follow similar pathologies. The overloading of lipids in the hepatocytes in most cases will be the first sign of the …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 43–52 Read article
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Explainable Machine Learning Integrated with Polymer-Based Diagnostic Technologies for Liver Health Classification
Abstract: Early and reliable assessment of liver health is essential for timely treatment, yet most machine-learning approaches face limitations such as class imbalance and low clinical interpretability. This study proposes a polymer-integrated, explainable machine-learning framework that combines SMOTE-based data balancing, Logistic Regression, and XAI techniques (SHAP and LIME) for transparent liver-health classification. In addition to ML modelling, the study emphasizes the emerging role of polymer-based biosensors, microfluidic polymer chips, polymer nanomaterials, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 631–643 Read article
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Awareness and Knowledge Regarding Hepatitis B Infection, Mode of Transmission and Prevention among People of Cameron Highlands, Malaysia
Abstract: The Hepatitis B virus (HBV) is a major cause of liver cirrhosis and hepatocellular carcinoma in humans. Every year 600,000 people die of illness related to HBV infection. This research is an attempt to study the awareness of HBV infection, modes of transmission and prevention among students, hospital personnel and public of Cameroon highlands of Malaysia. Majority of the hospital personnel are well aware of this infection and have adequate …
Published in Research and Reviews : A Journal of Immunology · Vol. 3, Issue 3, 2013 · pp. 11–17 Read article
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Mucormycosis during Second Wave of COVID-19
Abstract: Adding more burden to such a challenging situation, mucormycosis, an invasive fungal infection, has seen a sudden rise in the number of COVID-19 patients. The second wave affects Indians greatly with a mysterious fungal infection. Here, we are reviewed the clinical pathogenesis, signs and symptoms and treatment. The findings here showed that the use of immunosuppressants to combat COVID-19 also increases the risk of contracting mucormycosis. Patients suffering from hyperglycemia, …
Published in Research and Reviews : A Journal of Immunology · Vol. 12, Issue 1, 2022 · pp. 35–45 Read article
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A Clinical Study based Observation on Prevalence of Altered Liver Enzymes among Patients of Hepatobiliary Diseases Attending National Institute of Unani Medicine, India
Abstract: Background: Hepatobiliary disease is a major health problem responsible for millions of deaths annually. As reported, more than 40 million deaths occur annually in South-East Asia Region due to hepatobiliary diseases. This study was conducted as a clinical trial to assess the efficacy of Unani formulation, from which the data on prevalence of altered liver enzymes among patients of hepatobiliary diseases in which the study participants were collected and compiled …
Published in Research and Reviews: A Journal of Medicine · Vol. 11, Issue 1, 2021 · pp. 5–11 Read article
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Epidemiology and Clinical Profile of Liver Abscess from a Tertiary Care Hospital in Northern India
Abstract: Background: Liver abscess is defined as a localized collection of supportive material encapsulated within the liver parenchyma due to inflammatory necrosis secondary to bacterial, amoebic, tubercular, or fungal pathogens. Male gender, advanced age liver cirrhosis, proton pump inhibitors low socioeconomic status, alcoholism, diabetes, immunodeficiency states and poor hygiene are few of the risk factors mentioned in literature that are associated with Liver abscess. In the past decade, the treatment protocol …
Published in Research and Reviews : Journal of Surgery · Vol. 11, Issue 1, 2022 · pp. 1–6 Read article
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Survey of Liver Disease Prediction Using Machine Learning
Abstract: Liver disease is one of the major causes of death in all over world that impacts the number of people around the world. Diagnosis of liver at early stages is crucial to reduce morality. As technology is growing in health care, machine learning significantly affects health care for predicting conditions at early stages. This study reviews the different approaches based on machine learning and deep learning to predict liver disease. …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 10, Issue 1, 2023 · pp. 30–38 Read article