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187 articles for “chronic diseases”
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Advances in Biological Systems Modeling for Predicting Drug Effects in Chronic Disease
Abstract: Biological systems modeling has emerged as a promising tool for understanding and predicting the effects of drugs in the treatment of chronic diseases. Chronic diseases, such as diabetes, cardiovascular diseases, and neurodegenerative disorders pose significant challenges to traditional drug development due to their complex, multifactorial nature. Systems biology approaches, which integrate computational modeling with experimental data, provide a holistic view of disease mechanisms and treatment responses. This review explores recent …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 1, 2025 · pp. 17–22 Read article
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Flavonoids: An Answer to Chronic Diseases
Abstract: It has been shown that inflammation is closely associated with the onset or exacerbation of quite a few non-communicable human diseases. Several chronic diseases, such as cancer, diabetes, cardiovascular dysfunction and central nervous system damage are also developed following tissue injury produced by the high fragments of low-grade inflammation surrounding a compromised tissue or organ due to its acquired genomic changes. Current therapies for many of these diseases are associated …
Published in International Journal of Advance in Molecular Engineering · Vol. 2, Issue 1, 2024 · pp. 31–37 Read article
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Managing Chronic Diseases: Diabetes Mellitus
Abstract: Diabetes mellitus is one of the most prevalent chronic non-communicable diseases worldwide and represents a major public health challenge due to its long-term complications, increasing prevalence, and economic burden on individuals and healthcare systems. It is distinguished by chronic hyperglycemia brought on by deficiencies in either insulin action or secretion, or both. Diabetes causes increasing harm to several organ systems, including the kidneys, eyes, neurological system, and cardiovascular system, if …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article
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Clinical study of ERAS programs for chronic anal diseases
Abstract: Background: ERAS protocols were implemented for the management of chronic anal diseases in our clinical setting.Patients and Methods: The clinical outcomes of these ERAS programs were systematically analyzed. Results: Our study revealed significant improvements with the implemented ERAS protocols. Specifically, the average time for healing with these protocols was 7.9±0.76 days, notably shorter compared to the previous standard protocols which averaged 14.3±0.4 days. Moreover, there was a marked reduction in …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 2, 2024 · pp. 39–43 Read article
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Literature Review and Discussion of Machine Learning Algorithms for Predicting Chronic Kidney Disease
Abstract: Being one of the most serious and most occurring diseases in our era, chronic kidney disease requires a fast and correct diagnosis. The usage of machine learning in medicine has now grown to such a level that it could be a means of diagnosis. The doctor can be the first one to get the ailment by using machine learning classifier algorithms. This has been the data science sector’s new horizons, …
Published in Journal of Computer Technology & Applications · Vol. 15, Issue 3, 2024 · pp. 34–39 Read article
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The Clinical Landscape of Wogonin: Advancing Targeted Treatments for Chronic Diseases
Abstract: The traditional Chinese medicinal herb Scutellaria baicalensis Georgi, commonly known as Chinese skullcap or Huang-Qin, has long been used to treat a variety of conditions, including cancer, viral infections, and seizures. Its pharmacological effects are largely attributed to the high concentration of flavones, particularly wogonoside, and its aglycone derivative, wogonin. Among the bioactive compounds found in S. baicalensis, wogonin has garnered the most scientific attention due to its potent therapeutic …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 46–52 Read article
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A Study to Assess the Knowledge and Attitude Regarding Post Dialysis Dietary Regulations Among Care Givers of Chronic Kidney Disease Patient Undergoing Hemodialysis in Selected Hemodialysis Unit at Agartala, West Tripura
Abstract: Introduction and objectives of the study: - Chronic renal failure is a gradual, irreversible decline in kidney function, leading to uremia. This condition necessitates hemodialysis to manage the body's internal environment. Dialysis becomes essential at the final stage of chronic kidney disease, known as end-stage renal disease. Objectives of the study are as: i) The objectives of this study are: i) To evaluate caregivers' understanding of dietary regulations following dialysis …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 2, 2024 · pp. 89–103 Read article
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SGLT2 Inhibitors in Heart Failure and Chronic Kidney Disease: Expanding Therapeutic Horizons beyond Glycemic Control
Abstract: Heart failure (HF) and chronic kidney disease (CKD) are closely related clinical diseases that significantly increase morbidity and death worldwide. The co-occurrence of both conditions is frequently referred to as the "cardio-renal syndrome," in which the failure of one organ hastens the decline of the other. The original purpose of sodium–glucose cotransporter-2 (SGLT2) inhibitors was to treat type 2 diabetic mellitus (T2DM) by reducing blood sugar levels. Nevertheless, new data …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Assessment of Finerenone Safety and Efficacy in Individuals with Type 2 Diabetes and Chronic Kidney Disease
Abstract: Background: In this work, we provide strong evidence for the safety and efficacy of finerenone in people with type 2 diabetes and chronic kidney disease. Our goal is to improve patients' quality of life and general well-being through our research. Aim: Finerenone exhibited a significant decrease in the likelihood of renal and cardiovascular (CV) events in individuals with both type 2 diabetes and chronic kidney disease. This exploratory subgroup analysis …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 06–09 Read article
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Chronic Kidney Disease: A Comprehensive Review
Abstract: Chronic Kidney Disease (CKD) is a progressive condition characterized by a long-term decline in kidney function, leading to a gradual deterioration of the kidneys' ability to filter waste and maintain fluid balance. It is diagnosed when the Glomerular Filtration Rate (GFR) falls below 60 ml/min/1.73 m² or when there is evidence of kidney damage (such as proteinuria) lasting for 3 months or more. The most common causes of CKD are …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 37–42 Read article
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An Approach towards in Management of Chronic Kidney Disease
Abstract: The current international guidelines define and classify the chronic kidney disease (CKD) as decreased kidney function shown by decreased glomerular filtration rate (GFR). Glomerular filtration rate of 60 ml/min/1.73 m 2 for at least 3 months is a marker for kidney damage. The underlying causes for chronic kidney disease are proteinuria and hypertension. It is the main cause of CKD in many high-, middle- and low-income countries. In different countries, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 1, 2025 · pp. 9–15 Read article
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Integration of Biomarkers in III and IV CKD Patients for Evaluation of Their Predictive Value for CVD in CKD Patients
Abstract: Background: Chronic kidney disease (CKD) is presently characterized by the presence of proteinuria and/or a diagnosis of renal impairment. The worldwide significance of CKD is underscored by the fact that its prevalence and incidence have doubled over the past three decades. This paper provides an overview of the existing evidence regarding biomarkers in individuals with CVD or CKD, with a particular focus on the emerging biomarkers (i.e., eGFR, sALB, UACR, …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 3, 2025 · pp. 1–12 Read article
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A Study on the Incidence and Prevalence of Cardiovascular Morbidity and Mortality in Patients Undergoing Maintenance Hemodialysis
Abstract: Cardiovascular Disease (CVD) is a major complication for patients with end-stage renal disease (ESRD) on Hemodialysis (HD), with the mortality rate from CVD being nearly 20 times higher than in the general population. As Chronic Kidney Disease (CKD) advances, patients accumulate both traditional and kidney-specific cardiovascular risk factors, such as hypertension, diabetes, fluid overload, electrolyte imbalances, and uremic toxins. These factors contribute significantly to the increased cardiovascular morbidity and mortality …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 56–66 Read article
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Homeopathy and Miasms: Exploring Their Vital Importance
Abstract: An individual’s susceptibility to disease is not solely an internal matter but is also profoundly shaped by a variety of external influences. These influences can be broadly categorized into meteoric factors – such as climate, weather changes, seasonal variations, and atmospheric conditions – and telluric factors, which include environmental and terrestrial elements like soil, water, living conditions, and geographical surroundings. When such external influences act upon the human organism, they …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 3, 2025 · pp. 16–21 Read article
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Chronic Obstructive Pulmonary Disease (COPD) in Younger Adults: Challenges and Considerations – A Review
Abstract: Chronic Obstructive Pulmonary Disease (COPD) phenomenon rapidly converting into chronic significant health issues for many young adults. A disease calculated for older age gives way to early-onset COPD, which creates new issues for diagnosing and treating the illness and even interacts with the quality of life. The article reviews the epidemiology, risk factors, pathophysiology, clinical presentation, and treatment considerations related to this set of conditions. From those risk factors, early-onset …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 08–19 Read article
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A Review Article on Spice up the Solution of Inflammation Through Phytomedicines
Abstract: Inflammation is a complex, protective immune response essential for healing and combating infection. However, prolonged inflammation is associated with chronic diseases, such as arthritis, cardiovascular disorders, diabetes, and neurodegenerative conditions. Traditional nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids can exhibit adverse effects, particularly with chronic administration. This challenge has encouraged the exploration of natural alternatives. Among various natural anti-inflammatory agents, spices, such as ginger, garlic, turmeric, cardamom, and black pepper have …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 1, 2025 · pp. 1–10 Read article
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Role of Diet on BMI in Muslim Population of Jamia Nagar, New Delhi
Abstract: The aim of this study was to see the effect of diet mainly non-vegetarian on Muslim population on basal metabolic rate, that is, BMR. It has been found that BMR increases with the consumption of non-vegetarian diet. The study found that the average BMR level in the group exceeded 30, placing them in the obese category. This suggests a significant link between diet, particularly a non-vegetarian one, and increased BMR. …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 3, 2024 · pp. 1–5 Read article
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Infective Endocarditis, Result of Chronic Periodontal Disease: A Real and Present Danger
Abstract: Introduction: Endocarditis is an inflammation of the endocardium, the inner lining of the heart and heart valves. It is usually caused by bacteria and is associated with high mortality and morbidity. It can result from transient bacteremia from the oral cavity. Streptococci are the primary colonizers of tooth surface and are instrumental in development of the complex oral biofilm, dental plaque. Streptococcus sanguinis is one of the abundant oral commensals …
Published in Research and Reviews: A Journal of Dentistry Read article
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Review on Spirulina ( Green Alage)
Abstract: Spirulina is an edible blue-green algae that is a plant protein source. In recent years, its health benefits have attracted scientific attention, including micro-level examinations of the algae's bioactive components. As proof of concept, investigations conducted in vitro, in vivo, and ex vivo have shown how spirulina works and how it affects immunity. Spirulina has been used as a whole food and as a nutritional supplement for many years. It …
Published in International Journal of Pathogens · Vol. 1, Issue 1, 2024 · pp. 33–37 Read article
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Biodegradable Polymer Composite Materials for Long-Term Drug Release in Pharmacotherapy
Abstract: Biodegradable Polymer composite materials are a promising choice for controlled drug delivery because they let medicine be released slowly over time during treatment. These structures, which are made from safe, recyclable plastics, work well to make sure that drugs stay in the body for a long time. This means that patients will take their medicine less often and more consistently. As the body breaks down these structures, the drug inside …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 533–546 Read article