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23 articles for “anti-tumour”
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Anti-Tumour and Anti-Bacterial Activity of Some Ethno-Medicinal Plants
Abstract: Background: Every year, millions of people are diagnosed with cancer, leading to death in a majority of the cases. Because of the high death rate associated with cancer and serious side effects of chemotherapy and radiation therapy, many cancer patients seek alternative methods of treatment. Regarding the safety and effectiveness of natural therapies, the researchers are more interested in the use of natural medicine. In the present investigation, the anti-tumour …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 3, 2017 · pp. 16–22 Read article
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Anti-tumour Effects of Green Synthesis of Silver Nanoparticles from Helicteres isora L: In Vitro Approach
Abstract: Green synthesized silver nanoparticles preparation from 1mM AgNo3 solution through the fruit extract of Helicteres isora. in the range of 24–30 nm with increased stability and enhanced anti-tumour potency were reported in this present study. Green synthesized silver nanoparticles from fruit extract of H. isora (Hif-AgNPs) were characterized by using UV-VIS absorption spectroscopy and the morphology of the nanoparticles was characterized by transmission electron microscopy (TEM). The anti-tumour efficacy was …
Published in Trends in Drug Delivery · Vol. 5, Issue 1, 2018 · pp. 1–5 Read article
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Mechanistic Studies on Aziridinyl-Benzoquinones in Cultured Tumour Cells
Abstract: This study compares the anti-tumour effects of NQO1 activated drug RH1 (2, 5-diaziridinyl-3 - hydoxymethyl-6-methyl-1, 4-benzoquinone) with a lipophilic ester derivative Es5 on the isogenic cell lines MDA 468 and MDA 468 NQO1 which differs only in expression of wtNQO1. A 39- fold enhancement of growth inhibitory activity was seen in NQO1 expressing cells compared the NQO1 null cells for the Es5 compared to the 25- fold increase seen for …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 11, Issue 2, 2023 · pp. 37–45 Read article
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Personalised Cancer Vaccination Strategies: Bridging Genomics, Bioinformatics, and Immunotherapy
Abstract: Immunotherapy has revolutionized cancer treatment by harnessing the body’s immune system to detect and destroy cancer cells. Personalised cancer vaccines are one of the most promising options because they could allow treatment to be based on the specific tumour profile of each person. The goal of these vaccines is to make the immune system recognise and fight cancer-specific antigens, which will lead to strong and long-lasting anti-tumor responses. However, moving …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 3, 2025 Read article
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Therapeutic Potential of Composite Flour Prepared from EleusineCoracana and Cicer Arietinum
Abstract: Composite flour is a mixture of wheat and non - wheat flours used for the preparation of bakery products such as, breads, tarts, muffins, biscuits etc that is rich in protein and starch. Finger millet is considered as a special food supplement because of its unique nutritional properties when compared with other cereals. It is also known as poor man’s food. Many dishes, both in their natural and malted forms, …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 13, Issue 1, 2024 · pp. 31–41 Read article
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A Scientific Review on Phyto-pharmacological Properties of Moringa olifera Lam
Abstract: Moringa oleifera Lam. (Moringaceae) has been used since times to treat various health ailments. Different parts of plant have been used by traditional physicians. However, the dried entire fruit is more commonly used as Sehjana in Unani Medicine. Sehjana is a famous Indian drug used in a number of pathological conditions. Various parts of this plant act as cardiac and circulatory stimulants, possess anti-tumour, antipyretic, antiepileptic, anti-inflammatory, antiulcer, antispasmodic, diuretic, …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 7, Issue 3, 2020 · pp. 1–11 Read article
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Assessment of Antibacterial Potentialities of Diacetaldehyde Terpenoid Isolated from Curcuma Caesia Roxb. Against a Panel of Pathogenic Bacteria
Abstract: Assessment of antibacterial potentialities of a diacetaldehyde terpenoid was performed in this paper against a panel of pathogenic bacterial strains. This terpenoid was isolated from Curcuma caesia Roxb. and found to have several kinds of biological activities like antibacterial, antifungal and antitumour. In this experiment it was found that the terpenoid can inhibit the growth of bacterium at 150 to 200 μg/ml of concentrations. Hence, this terpenoid can be used …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 1, 2020 · pp. 13–16 Read article
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The Therapeutic Repertoire of Turmeric
Abstract: ABSTRACTTurmeric has been used in the treatment of arthritis, and other inflammatory conditions, for ages. Its healing constituent, curcumin, has been found to curb the incendiary activity of the COX-2 and lipooxygenase, the two enzymes involved in elevating and sustaining inflammation. It is also suggested that curcumin has a protective effect on the liver, thanks to its anti-tumour resolve, aside from its ability to easing inflammation and combating infections. This …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 5, Issue 2, 2018 · pp. 1–9 Read article
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Cancer Prevention Activity in Vitro and the Mechanism of Action Bioactive Ingredients
Abstract: Natural substances that can treat a variety of ailments, including cancer, can be found in the Solanaceae plant family. There is still uncertainty regarding the location and mode of action of these substances in cells. Several of the cellular targets can now be studied and identified thanks to increasing advances in biological science research. The relevant studies that describe how some of these substances may fight cancer are found in …
Published in Journal of Catalyst & Catalysis · Vol. 9, Issue 2, 2022 · pp. 20–25 Read article
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Extraction, Isolation, Characterization of Curcumin-I From Curcuminoids
Abstract: The major goal of this study is to extract, isolate, and characterize curcumin-I, a component of curcuminoids. Turmeric, or Curcuma longa Linn., plays a significant role in Ayurvedic medicine. Turmeric, or Curcuma longa Linn, is the popular name for this plant. An array of chemicals with biological activity may be more easily extracted with the help of this seasoning. Some of the compounds at play include curcuminoids and turmerone, although …
Published in Journal of Polymer & Composites Read article
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Visualization of genomic sequence in BRCA1 and BRCA2
Abstract: Heredity is the main reason of breast cancer in women and mutation or genetic variations also another reason for the spread of breast cancer. Heredity and genetic variations are responsible 5%-10%, 30%-50% respectively. There are 90% chances of developing neoplasm by the mutations. The effect of BRCA1 and BRCA2 may leads to the variations in DNA therefore it should be in limited amounts so that there will be minimum changes …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 49–55 Read article
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Podophyllum hexandrum: A Rare Alpine Medicinal Herb, Reservoir of Bioactive molecules
Abstract: In the Ayurvedic medical system, Podophyllum hexandrum, a well-known and important medicinal plant from the family Berberidaceae, is frequently used to treat ailments like constipation, colds, fevers, septic wounds, inflammation, burning sensations, mental disorders, genital warts, and various cancer types. This herb, which prefers moisture and shade and grows at heights between 2500 and 4000 metres, is native to the Kashmir to Sikkim region of the Himalayas. According to reports, …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 14, Issue 1, 2023 · pp. 47–55 Read article
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A REVIEW: P-GLYCOPROTEIN AND ITS ROLE IN CANCER
Abstract: Abstract The review is done on how P-glycoprotein recognizes various substrates and plays a key role in cancer. Chemotherapy is used for cancer treatment but multidrug resistance of cancerous cell is the major obstacle in therapy and also an important aspect which causes failure in the treatment by effluxion of a xenobiotic on the plasma membrane. In humans, P-glycoprotein is important transmembrane transporter. It is located on the apical surface …
Published in Trends in Drug Delivery · Vol. 7, Issue 2, 2020 · pp. 26–34 Read article
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Current Tumour Immunotherapy strategies and their molecular basis
Abstract: AbstractStudying cancer and devising techniques to combat the deadly disease has witnessed a paradigm shift, from conventional toxic treatments of radiation and chemotherapy, to a more specific, and biologically significant immunotherapy and molecular targeted therapy. This can be seen in the global immunotherapy market, which is dominated by North America region valued about $45.9 billion in 2017 that is estimated to reach about $115.9 billion by 2025, and is closely …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 2, 2020 · pp. 1–18 Read article
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Molecular Docking Analysis of Phytocompounds from Ficus hispida Aagainst Epidermal Growth Factor Receptor Kinase Domain
Abstract: The Epidermal Growth Factor Receptor (EGFR) kinase domain plays a key role in cancer, as it promotes tumour growth and helps cancer cells survive, making it an important focus for developing treatments. Through comprehensive computational analysis, this study investigates the anticancer potential of phytocompounds from Ficus hispida, a medicinal plant renowned for its diverse bioactive compounds, as novel EGFR inhibitors. Molecular docking techniques using Py Rx software were employed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 Read article
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Molecular Docking Analysis of Phytocompounds from Ficus hispida Against Epidermal Growth Factor Receptor Kinase Domain
Abstract: The Epidermal Growth Factor Receptor (EGFR) kinase domain plays a key role in cancer, as it promotes tumour growth and helps cancer cells survive, making it an important focus for developing treatments. Through comprehensive computational analysis, this study investigates the anticancer potential of phytocompounds from Ficus hispida, a medicinal plant renowned for its diverse bioactive compounds, as novel EGFR inhibitors. Molecular docking techniques using Py Rx software were employed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 48–62 Read article
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Oxidative stress analysis of cancer patient treated with Radiotherapy
Abstract: Oxidative stress is a term given to overload of free radicals in the body caused by an imbalance between levels of free radicals and antioxidants in the body. Reactive Oxygen Species (ROS) are free radicals also known as oxygen radicals that are produced by various physiological reactions inside the body leading to increasing oxidative stress that can lead to cell death. In case of cancer management, radiation therapy works by …
Published in Trends in Drug Delivery · Vol. 10, Issue 1, 2023 · pp. 28–31 Read article
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Inhibition of Ehrlich Ascites Carcinoma by Crotalaria verrucosa L. Leaf in Swiss Albino Mice
Abstract: Objective: The objective of the present study was to evaluate the antitumor activity of Crotalaria verrucosa L. leaf against Ehrlich ascites carcinoma (EAC) in Swiss albino mice. Methods: The in vivo antitumour activity of the ethanol extract of leaf of C. verrucosa L. (ELCV) was evaluated at 50, 100 and 200 mg/kg bw against EAC, using mean survival time. After administration of the extract of C. verrucosa, viable EAC cell …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 5, Issue 2, 2018 · pp. 5–10 Read article
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Up-Regulation of TNF-α by Ethanol Extract of Moringa Oleifera in Benzene-Induced Leukemic Wister Rat: A Possible Mechanism of Anticancer Property
Abstract: Ethanol extract of Monringa oleifera (EMO) has been shown to possess anti-cancer properties in animal models. The mechanisms of action of its anticancer properties have not been fully demonstrated. We induced leukemia in two groups of seven rats each by intravenous injection of benzene chromasolv solution (0.2 mL) 48 hourly for 4 weeks. EMO (0.2 ml of 100 mg/mL) was administered orally by gavage, after leukemia induction, daily for 4 …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 3, Issue 3, 2014 · pp. 16–21 Read article
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Recent Development Technique in Management of Cancer
Abstract: Cancer develops when a change in one's genetic makeup leads to the development of tumour cells. These clusters of malignant cells eventually develop into tumours. Tumours can shed cancerous cells, which can then travel through the lymphatic system or the circulatory system to other organs. In the medical field, this occurrence is referred to as metastasis. Cancer cells proliferate even when they have no instructions to do so. Despite the …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 25–41 Read article