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169 articles for “Validation”
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Experimental Validation and Implementation Framework for Optimized Methane Yield Prediction in Anaerobic Digestion
Abstract: The correct validation and realistic application of optimized anaerobic digestion (AD) models are essential steps in transferring biogas production systems to real-life. This paper outlines an experimental validation and deployment pipeline of an AI-optimized model of the methane yield prediction model based on the application of more advanced machine learning and Bayesian optimization methods. Others The validated surrogate-assisted optimization model was tested with controlled laboratory-scale AD experiments at optimized operating …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 4, Issue 1, 2026 · pp. 25–32 Read article
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Development and Validation of a Robust RP-HPLC Method for Rufinamide Quantification in Pharmaceutical Dosage Forms
Abstract: The creation and validation of a simple, precise, and targeted reverse phase high-performance liquid chromatographic (RP-HPLC) approach allowed for the quantification of rufinamide in pharmaceutical dosage forms. With a mobile phase of methanol and water (50:50, v/v), the technique used a gradient mode Symmetry Qualisil gold C18 column (4.6 x 150mm, 5 μm). For the detection method, a flow rate of 1 mL/min was employed at 220 nm. During a …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 25–32 Read article
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Photochemically Assisted LC–MS Method Development and Validation for Stability-Indicating Determination of Glasdegib in Rat Plasma
Abstract: A simple, precise, and cost-effective LC–MS method was successfully developed for the determination of Glasdegib in rat plasma. The method optimization was carried out by systematically varying key chromatographic parameters, including flow rate, injection volume, analyte concentration, and mobile phase composition, to achieve optimal sensitivity and resolution. A C18 Hypersil BDS column (150 mm × 4.6 mm, 3.5 µm particle size) was used for chromatographic separation, offering effective peak shape …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 11–20 Read article
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Lamivudine And Dolutegravir Simultaneous Dosage Forms Determined and Validated Using The RP-UPLC Method
Abstract: RP-UPLC has been used to produce a straightforward, precise, and accurate approach for the simultaneous estimation of dolutegravir and lamivudine in a pharmaceutical dose form. A HSS C18 column of 2.8 x 50 mm and featuring particles with a size of 1.6 μm was used to process the chromatogram. A mixture of 70:30 Buffer Na2HPO4 and methanol made up the mobile phase, which was pushed across the column at a …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 5–13 Read article
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Unlocking Science Potential: Developing a New Attitude Scale SS-SAS for Young Learners
Abstract: The aim of this examination is to develop an attitude scale for measurement of scientific attitude of upper primary students. The development was carried out by researchers with the help of 20 subject area experts, and 240 students of approved schools of state of Rajasthan State/central boards BE/CBSE board studying in classes 6–8. The study consists of five parts, namely literature review, components of scientific attitude to be measured, development …
Published in International Journal of Behavioral Sciences · Vol. 2, Issue 2, 2025 · pp. 66–73 Read article
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Performance, Combustion and Emission analysis of Sunflower oil based Biodiesel using Non-Dominated Sorting Genetic Algorithm-II
Abstract: Biodiesel is used as alternate fuel of I. C. Engines for so many years. It is obtained from various edible and non-edible oils including waste cooking oils through trans-esterification process in the presence of catalyst. The suitable amount of biodiesel mix with commercial diesel can be used to run the compression ignition engines. The optimum combination of engine input parameters is the challenging task as required by the design engineer …
Published in International Journal of Energy and Thermal Applications · Vol. 1, Issue 1, 2023 · pp. 1–6 Read article
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Exploring Glucagon-like peptide-1 as a Target Protein for Diabetes Mellitus Treatment: Molecular Docking and Pharmacokinetic Analysis of Phytocompounds from Momordica charantia
Abstract: Objective: This study aimed to use molecular docking techniques to explore the potential of GLP-1 (glucagon-like peptide-1) as a target protein for the treatment of diabetes mellitus, a chronic metabolic disease marked by elevated blood glucose levels. Given its crucial role in maintaining insulin secretion and glucose homeostasis, GLP-1 may serve as a future target for diabetes therapy. Method: The study employed a multi-phase method. Initially, protein extraction was carried …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 8–20 Read article
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Novel Laplace-domain Approach to the Electromagnetic Transients in Compensated High Voltage Power Lines
Abstract: This paper addresses the simulation of the electromagnetic transients developed in high voltage power lines, which are initiated by lightning discharges. The analysis can handle both individual and simultaneous series inductive and shunt capacitive compensation types. The sizes and locations of the compensating elements are included in the analysis. The derived Laplace s-domain mathematical model applies the concept of the ABCD transmission constants representing equivalent two-port networks. Applying the relations …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 2, Issue 1, 2024 · pp. 15–21 Read article
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Pharmacophore mapping, 3D QSAR, docking, and ADME prediction studies of novel Benzothiazinone derivatives
Abstract: Background Tuberculosis is a major public health concern worldwide which is caused by Mycobacterium tuberculosis. DprE1 (Decaprenyl Phosphoryl Ribose 2’- Epimerase) is the most challenging target for development of novel anti- tubercular agents because it is a small protein and located into cytoplasmic membrane. So, novel anti-TB drugs did not bound effectively with it. DprE1 catalyzes the oxidation of the 2’ hydroxyl group of DPR (Decaprenyl Phosphoryl D- Ribose) …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 59–82 Read article
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Effects of Reels and short videos on human mind and Academic Life
Abstract: The rapid rise of short-form video platforms such as Instagram Reels, TikTok, and YouTube Shorts has fundamentally reshaped the way people consume information and entertainment. While these applications offer quick engagement and social connection, their excessive use has raised serious concerns about their psychological and academic impacts. This research investigates the relationship between short-form video addiction, mindfulness, academic anxiety, and academic engagement among university students. Drawing upon the theoretical framework …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 2, 2026 Read article
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Relationship Between Mental Health, Competitive Aggression and Anger Rumination with Regard to the Role of Mental Health of Martial Arts Athletes in Gilan Province
Abstract: Due to the phenomenon of championship in sports, athletes are always very thirsty to achieve the championship and go on the podium, and this factor can cause negative behaviors by athletes, one of which is competitive aggression. Therefore, the main purpose of this study is to investigate the relationship between mental health, competitive aggression and anger rumination with regard to the role of mental health of martial artists in Gilan …
Published in Recent Trends in Sports · Vol. 1, Issue 1, 2024 · pp. 1–10 Read article
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DFT/Data Guided Predictive Modelling of Absorption Maxima in the OLED Rubrene Derivatives
Abstract: This study investigates the optical properties of rubrene derivatives to develop an accurate predictive model for absorption maxima using computational chemistry and chemoinformatic techniques. We benchmarked various quantum chemical methods, identifying that the M06-2X/aug-cc-pVDZ method in dichloromethane (DCM) provided the strongest correlation with experimental data. Key molecular descriptors such as band gap, ionization potential, and electrophilicity index were calculated and analyzed using principal component analysis (PCA) to identify significant factors …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 41–56 Read article
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A Novel Approach to Fingerprint Authentication Using Histogram Oriented Gradients for Feature Extraction and Machine Learning Convolution Neural Network for Classification
Abstract: With applied biometrics, it is possible to identify a person by examining a feature vector of attributes derived from their physical and behaviour characteristics. In biometrics, fingerprints have become one of the most famous and well known techniques of identification and authentication. In light of technological advancements and safety, fingerprint recognition has been successfully used in a variety of Civil, Defence, and Commercial applications for more than a decade. The …
Published in International Journal of Wireless Security and Networks · Vol. 1, Issue 2, 2023 · pp. 1–12 Read article
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Secured Communication and Image Authentication: Embedding Encrypted Text Files Into Color Digital Images
Abstract: In today's digital landscape, protecting digital assets, particularly images, is paramount. Researchers have developed various techniques to safeguard these assets, emphasizing their protection and integrity. Simultaneously, steganography plays a crucial role in securely communicating confidential messages. This paper focuses on a dual-purpose technique: watermarking color digital images for protection and embedding secret messages through steganography. This fusion of functionalities represents a significant step in comprehensive asset protection and confidential communication …
Published in International Journal of Information Security Engineering · Vol. 2, Issue 1, 2024 · pp. 10–15 Read article
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Presenting the Model and Prioritization of Lean Production Success Drivers (Case study: Iran Khodro Company)
Abstract: The purpose of the current research is to present a model and prioritize the drivers of lean production success (case study: Iran Khodro Company). The statistical population and statistical sample of this study consists of 20 experts (managers) of Iran Khodro production department. In this research, first, the most important key success factors of lean production were determined using the validity technique of the content validity ratio, then the interpretative …
Published in International Journal of Sustainability · Vol. 1, Issue 1, 2024 · pp. 30–42 Read article
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InSilico Analysis and Homology Modeling of Tetrahydroprotoberberine Oxide involved in the Berberine Biosynthesis
Abstract: Objective: Berberine, a bioactive compound found in various plant species, exhibits diverse pharmacological properties with potential applications in pharmaceutical research. The biosynthesis of berberine involves several enzymatic steps, with (S)-tetrahydroprotoberberine oxidase playing a pivotal role. This study aimed to elucidate the structural and functional characteristics of (S)-tetrahydroprotoberberine oxidase to better understand its role in berberine biosynthesis and its potential biotechnological applications. Methods: Using bioinformatics tools and computational methods, the physicochemical …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 7–26 Read article
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Anti-hyperglycemia Effects of Plant Secondary Metabolites Towards PKA/CREB Pathway Activation in Diabesity
Abstract: Objective: Diabesity, the amalgamation of diabetes and obesity, presents a significant global health challenge. This research carefully examines how plant secondary metabolites influence glucose regulation in diabetes using the PKA/CREB pathway, paying particular attention to diabesity—the combination of diabetes and obesity. Understanding the complex ways in which these metabolites affect metabolic health will help to identify new treatment approaches for managing diabetes and its associated problems. By conducting a thorough …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 33–50 Read article
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Intimate Mappings in Interval-Valued Fuzzy Metric Space: A Few Fixed-Point Findings
Abstract: The purpose of this study is to extend some previously established fixed point results for interval valued fuzzy metric space. For this objective, various contractive criteria with respect to an intimate mapping are applied. We employ intimate mapping in interval valued fuzzy metric space (IVFMS) to validate some well-known fixed point results. Our findings complement and generalize the recent findings of the common fixed point theorem for intimate mapping. The …
Published in Recent Trends in Mathematics · Vol. 1, Issue 1, 2024 · pp. 16–23 Read article
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Exploring Potential Phytochemicals for Myasthenia Gravis Treatment: A Molecular Docking and ADME Analysis Approach
Abstract: Objective: Muscle feebleness and exhaustion derived from a disruption in neuromuscular transference are hallmarks of the crippling autoimmune disease myasthenia gravis (MG). The drawbacks of the current MG therapy options are frequently partial efficacy and adverse effects. To investigate the potential of phytochemicals in MG control, in this work we integrated molecular docking with ADME (absorption, distribution, metabolism, and excretion) analysis using a computer method. We identified molecules exhibiting favorable …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 1–13 Read article
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Development of Automobile Scaled Model from CAD (Blender) Using FDM 3D Printing
Abstract: Additive manufacturing (AM), also known as 3D printing, has emerged as a disruptive technology with the potential to transform automotive manufacturing. This paper reviews the applications of AM across the automotive product development lifecycle. The paper examines case studies demonstrating the use of AM for developing computer-aided design (CAD) models from concept sketches. Overall, AM brings several benefits such as design flexibility, faster time-to-market, and distributed production. However, there are …
Published in International Journal of Advanced Control and System Engineering · Vol. 2, Issue 2, 2024 · pp. 1–9 Read article