Search
843 articles for “Structure-Based”
-
IoT-Based Structural Health Monitoring and Damage Detection in Fiber Reinforced Polymer Composite Structures
Abstract: Applications of fiber-reinforced polymer (FRP) composite in the aerospace, civil infrastructure and renewable energy systems are increasing due to the fact that the composite possesses high ratio of strength to weight and can resist corrosion. However, processes of internal damages such as the cracking of the matrix, delamination and fiber fracture, are likely to take place without being visible on the surface and therefore a periodic check of the structure …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1076–1100 Read article
-
ML-Enhanced Smart Sensing Framework for IoT- Based Structural Health Monitoring Using Conductive Polymer Composites
Abstract: The growing demand for intelligent structural health monitoring (SHM) in dynamic infrastructures necessitates flexible sensing systems that are not only mechanically robust but also capable of real-time interpretation. Conventional SHM frameworks often rely on brittle sensor configurations and cloud-dependent processing pipelines, which suffer from latency, limited durability, and poor adaptability under variable loading conditions. Despite recent advances in composite materials and machine learning, current approaches lack a unified framework that …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 348–369 Read article
-
A Structure-based Design Approach to Catharanthus roseus Phytoconstituents as Potential Inhibitors of B-Cell Lymphoma 6 Protein
Abstract: Objectives: Lymphoma is a cancerous disease. It develops into millions of people worldwide. Identify the naturally active compounds from Catharanthus roseus, they have multiple values in the medicinal field of Siddha, and Indian Ayurveda are used as a disease-preventing agent. Drug illness prediction, toxicity prediction, statistical information, molecular docking, as well as absorption, distribution, metabolism, and excretion (ADME) analysis are used to predict the fit ligand as a drug. Methods: …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 14–34 Read article
-
Computer Aided Drug Designing for Targeted Drug Delivery Systems
Abstract: The discovery and development of a contemporary sedate is widely acknowledged as an extremely difficult task that requires significant resources and effort. Therefore, computer-aided medication design techniques are widely utilized today to increase the productivity of the drug discovery and development process. Among structure-based and ligand-based drug design approaches, both recognized for their efficiency in drug discovery and development, various CADD (Computer-Aided Drug Design) techniques are evaluated based on specific …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 34–41 Read article
-
Illuminating the Frontier of Drug Discovery: Unleashing the Power of Bioinformatics for Unprecedented Breakthroughs
Abstract: It takes a long time and a lot of effort to discover and develop new drugs, which necessitates extensive study and testing. With the help of computational techniques and data analysis, bioinformatics has grown to be a potent tool for drug discovery in recent years, allowing researchers to find new drugs faster. In this review, we examine the role of bioinformatics in drug discovery, including the use of ligand- and …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 1–10 Read article
-
Optimizing Keyword Querying on Structured Knowledge Bases
Abstract: As the digital landscape burgeons with unstructured information, the need for structured knowledge bases becomes paramount. The Semantic Web employs Resource Description Framework and SPARQL as a cornerstone in organizing information. This work explores keyword querying approaches on knowledge bases such as Freebase, emphasizing their usability challenges, particularly in complex queries. Existing approaches, while valuable, exhibit limitations in handling intricate queries with multiple joins. The proposed Entity Relationship Keyword Querying …
Published in Journal of Web Engineering & Technology · Vol. 11, Issue 2, 2024 · pp. 28–50 Read article
-
Experimental Investigation of Polymer Composite-Based Protective Structures for Mitigating Crash-Induced Mechanical Abuse in Lithium-Ion Batteries
Abstract: The objective of this paper is to determine the effectiveness of using polymer composite protective structures to protect against the mechanical abuses associated with crash impacts that affect lithium ion batteries in terms of their structural integrity and their overall safety. In addition to their use in electric vehicles, lithium ion batteries are also being increasingly used in renewable energy based energy storage systems because they have high energy densities, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
-
Targeting Papain-Like Protease of Re-Emerging Coronaviruses
Abstract: Re-emerging Corona viruses (CoVs), including SARS-CoV (S-CoVs), and SARS-CoV-2 (S-CoV-2), continue to pose a global health threat due to their high mutation rates, zoonotic spillover potential, and capacity for immune evasion. The global pandemic of year 2019, caused by S-CoV-2, has highlighted the importance for robust antiviral strategies beyond vaccines and RNA polymerase or main protease inhibitors, which are susceptible to resistance. One promising therapeutic target is the S-CoV-2 papain-like …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 46–62 Read article
-
An Extensive Analysis of Computer-Aided Drug Design for Novel Psychotropic and Neurological Substances
Abstract: A comprehensive review of the use of computer-aided drug design (CADD) in the creation of innovative neurologic and neuropsychiatric medications is given in this article. It discusses the challenges in traditional drug discovery approaches and highlights the role of computational methods in accelerating the identification and optimization of drug candidates targeting psychiatric and neurological disorders. The method of finding new drugs has been completely transformed by Computer-Aided Drug Design (CADD), …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 19–27 Read article
-
Computer-aided Drug Design Method for Anti-hepatitis C Drug Design
Abstract: Hepatitis C is a disease caused by the hepatitis C virus and can cause serious liver damage. There is currently no vaccine for this disease and the number of infections continues to increase worldwide. Currently used antiviral drugs are interferon alfa-2a and ribavirin, but about half of patients do not respond to therapy. Therefore, new drugs that protect against hepatitis C need to be investigated. Computational drug methods have been …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 1–8 Read article
-
Metamaterial-Based Thermal Shielding Structures for Reusable Hypersonic Space Transportation Systems
Abstract: The rapid development of reusable hypersonic space transportation systems has intensified the need for advanced thermal protection technologies capable of withstanding extreme aerodynamic heating conditions encountered during atmospheric re-entry and sustained hypersonic flight. Conventional thermal shielding materials often suffer from high structural weight, limited adaptability, thermal fatigue, and degradation under repeated thermal cycling. This study proposes a novel Metamaterial-Based Thermal Shielding Structure for Reusable Hypersonic Space Transportation Systems, integrating engineered …
Published in Journal of Aerospace Engineering & Technology · Vol. 16, Issue 2, 2026 Read article
-
Analyzing the Effects of Soil-Structure Interaction and Geometric Configuration on Structure
Abstract: This study investigates how varying soil types impact the seismic performance of a 30-story building, simulated using ETABS software. The research focuses on key parameters such as soil type, different shapes of structure, base shear, and inter-story drifts under different soil conditions, ranging from soft clay to dense sand. By comparing fixed-base models with those incorporating soil-structure interaction (SSI), the analysis highlights significant differences influenced by soil type. The findings …
Published in Journal of Geotechnical Engineering · Vol. 11, Issue 2, 2024 · pp. 1–15 Read article
-
Machine Learning Based Optimization of Polymer Structure Property Relationships in Composite Material Systems
Abstract: In modern engineering applications, polymer-based composite materials have garnered a lot of attention because of their lightweight nature, high strength-to-weight ratio, and changing physical features. In order to maximize the relationships between polymer structure and properties in composite materials, this study suggests a strategy based on reinforcement learning (RL). The research utilized the Polymer Composite Properties Dataset, which contains 12,700 records associated with polymer matrices, reinforcement fillers, interfacial bonding characteristics, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 242–255 Read article
-
Advancements in Polymer-Based Sensors and Actuators for Structural Health Monitoring in Aerospace: A Comprehensive Review of Emerging Trends
Abstract: Structural health monitoring (SHM) has emerged as a critical aspect of aerospace engineering, aiming to ensure the safety and reliability of aircraft structures throughout their operational lifespan. In aerospace engineering, structural health monitoring is one of the most important aspects of aerospace engineering. It aims to ensure that aircraft structures are safe and reliable over their entire service life. Polymer-based actuators and sensors have attracted a lot of attention because …
Published in Journal of Polymer & Composites · Vol. 12, Issue 4, 2024 · pp. 173–193 Read article
-
Machine Learning-Based Quantification of Polymer Structure Property Relationships for Predictive Material Design
Abstract: Polymer structures exhibit complex, hierarchical arrangements that strongly influence macroscopic properties, yet consistent quantification remains challenging due to nonlinear interactions and limited unified modeling strategies. Existing approaches inadequately capture generalized structure–property mappings across diverse polymer systems. This research aims to establish a machine learning-based quantification model for polymer structure–property relationships to support predictive material design. A Polymer Structure Property Dataset of 5,000 polymer samples includes structural descriptors and experimentally measured …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 737–754 Read article
-
Investigation of the Thermoelectric, Electronic Band Profile, and Structural Properties of Skutterudites Based on Cobalt and Antimony
Abstract: We investigated ThCo4Sb12, an actinium-filled skutterudite, from the ground up for structural, electronic, and thermoelectric properties. A generalized gradient approximation and modified BeckeJohnson potentials were used to calculate the exchange-correlation potential. The compound is shown to have metallic properties in the electronic structure calculations. Actinium series element is used as a void filler in this study. The Seebeck coefficient and electrical conductivity can be calculated using Boltzmann's transport theory. According …
Published in Journal of Structural Engineering and Management · Vol. 11, Issue 2, 2024 · pp. 13–19 Read article
-
Image-Based Quantitative Mapping of Structure Property Relationships in Polymer Composite Materials
Abstract: The performance of polymer composite materials is intrinsically governed by their microstructural architecture, which is shaped by manufacturing conditions and constituent interactions. Despite extensive experimental characterization efforts, establishing transparent and quantitative structure–property relationships from microstructural images remains a challenge. In this study, an explainable image-driven framework is developed to systematically correlate microstructural features with composite property indicators. Microstructure images are processed to identify voids, fibers, and filler phases, from which …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 188–196 Read article
-
Emerging Trends in Data Structures for Modern Machine Learning Applications
Abstract: In the realm of machine learning, data structures play a pivotal role in facilitating efficient data manipulation, storage, and retrieval, thereby significantly impacting the performance and scalability of machine learning algorithms. In recent years, the field of machine learning has witnessed the emergence of novel data structures tailored to address scalability and efficiency challenges inherent in handling large-scale and high-dimensional data. This study provides a look at the data preprocessing, …
Published in International Journal of Data Structure Studies · Vol. 2, Issue 1, 2024 · pp. 1–7 Read article
-
Comparative Analysis of using Rubber isolator and Friction isolator in G+8 Building by SAP 2000
Abstract: Base isolation technique has become most popular that improves resistant quality during a seismic earthquake. These bases seclude moves under high pressure and they soak up an earth tremor smash by minimizing oscillating and trembling of ground. Adaptive base solitude system includes the separation system is Lead Rubber Bearing, Friction Isolators, channel Method, Laminated Rubber Bearing. Base separation is the broadly accepted seismic protected skeleton employed in any edifice in …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 479–487 Read article
-
Modern Computer-aided Drug Design Methods: A Review
Abstract: Computer-aided drug design (CADD) has emerged as a crucial tool in the drug discovery process, offering a time-efficient and cost-effective approach to identifying potential drug candidates. This review aims to provide an overview of modern CADD methods, including high-throughput screening (HTS), structure-based drug design (SBDD), ligand-based drug design (LBDD), structure-based virtual screening (SBVS), and ligand-based virtual screening (LBVS). We discuss the basic principles, applicability, and limitations of each method, highlighting …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 2, 2024 · pp. 14–20 Read article