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9 articles for “Structure-Activity Relationships”
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A Review on Anesthetic Drug Discovery with Computer Aided Drug Design
Abstract: In contemporary medicine, anaesthesia is essential for enabling surgical procedures, pain control, and patient comfort. Finding and creating safe and efficient anaesthetics is crucial to enhancing patient outcomes and developing the medical field. In this review, we provide a comprehensive overview of anesthetic drug discovery with a focus on the integration of computer-aided drug design (CADD) methodologies. Beginning with an exploration of anesthesia mechanisms and targets, we delve into the …
Published in International Journal of Antibiotics Read article
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Heterocyclic Substituted Flavones: Bridging Natural Products and Medicinal Chemistry
Abstract: Heterocyclic substituted flavones represent a unique and promising class of flavonoid derivatives, gaining significant attention in recent years due to their diverse and enhanced biological activities. These compounds are characterized by the incorporation of heterocyclic moieties such as quinoline, pyridine, thiazole, imidazole, oxazole, and pyrazole into the flavone structure, which significantly alters and often enhances their bioactive properties. This structural modification has made heterocyclic flavones particularly appealing as candidates for …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 23–30 Read article
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Advancements in Drug Design Technology and Its Impact on COVID-19 Treatment
Abstract: The deadly coronavirus disease 19 (COVID-19) pandemic has recently spread, raising concerns about global health. The search for novel therapeutic compounds is made more necessary by the persistent problem of the absence of licensed medications or vaccinations. By saving money and time, computer-aided drug design has sped up the process of finding and developing new drugs. The structured-based and ligand-based drug discovery subcategories of computer-aided drug design (CADD) are the …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 1–15 Read article
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An Extensive Analysis of Computer-Aided Drug Design for Novel Psychotropic and Neurological Substances
Abstract: A comprehensive review of the use of computer-aided drug design (CADD) in the creation of innovative neurologic and neuropsychiatric medications is given in this article. It discusses the challenges in traditional drug discovery approaches and highlights the role of computational methods in accelerating the identification and optimization of drug candidates targeting psychiatric and neurological disorders. The method of finding new drugs has been completely transformed by Computer-Aided Drug Design (CADD), …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 19–27 Read article
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Association Between Smartphone Addiction and Functional Exercise Capacity in College Students
Abstract: Smartphone addiction has become increasingly prevalent among college students and is associated with various negative physical and psychological outcomes. Functional exercise capacity, a key indicator of physical fitness and health, may be adversely affected by excessive smartphone use due to sedentary behavior and reduced physical activity. This article examines the association between smartphone addiction and functional exercise capacity in college students by analysing behavioral, psychological, physiological, and methodological perspectives. Evidence …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 4, Issue 1, 2026 Read article
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Effect of Skin Barrier Damage on Absorption and Action of Cosmeceuticals
Abstract: The skin acts as a primary defensive barrier protecting the human body against environmental aggressors, microbial invasion, and chemical exposure. The integrity of the skin barrier, particularly the stratum corneum, plays a crucial role in regulating the permeation of substances applied topically. Cosmeceuticals, a hybrid category between cosmetics and pharmaceuticals, are designed to deliver biologically active ingredients into the skin to exert therapeutic or beneficial effects. However, the condition of …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 2, 2026 · pp. 1–19 Read article
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Assessing the Socioeconomic Impacts of Land Tenure Systems Across Different Regions
Abstract: Land tenure systems are fundamental in shaping the socioeconomic structure and dynamics of communities across the globe. These systems, which define the legal and customary relationship between individuals, groups, and the land they own, use, or occupy, hold significant implications for economic development, social equity, and environmental sustainability. They determine how land resources are accessed, managed, and transferred, thereby influencing economic activities, wealth distribution, and community stability. This article provides …
Published in International Journal of Land · Vol. 2, Issue 1, 2025 · pp. 24–27 Read article
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Relationship Between Mental Health, Competitive Aggression and Anger Rumination with Regard to the Role of Mental Health of Martial Arts Athletes in Gilan Province
Abstract: Due to the phenomenon of championship in sports, athletes are always very thirsty to achieve the championship and go on the podium, and this factor can cause negative behaviors by athletes, one of which is competitive aggression. Therefore, the main purpose of this study is to investigate the relationship between mental health, competitive aggression and anger rumination with regard to the role of mental health of martial artists in Gilan …
Published in Recent Trends in Sports · Vol. 1, Issue 1, 2024 · pp. 1–10 Read article
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Integrating Co-Curricular Activities with Academic Achievement in Light of NEP 2020 and NCF-SE
Abstract: This research paper investigates the impact of co-curricular activities on the academic achievement of senior secondary students. The study emphasizes the significance of holistic development in education, where co-curricular activities (CCAs) play a vital role alongside formal academics. CCAs include a range of non-classroom engagements such as debates, music, sports, drama, arts, and community service that contribute to the cognitive, social, emotional, and physical growth of students. These activities are …
Published in International Journal of Education Sciences · Vol. 2, Issue 2, 2025 · pp. 59–66 Read article