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191 articles for “Pharmaceutical activities.”
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Pharmaceutical Activity of Mirabilis Jalapa and its Biogenesis of Nanocrystals
Abstract: Bio friendly green modest synthesis of nanoparticles are the present research in nanotechnology. This study has been undertaken to explore the determinants of copper nanoparticles from 1 mM CuSO4 solution through profuse concentration of aqueous flower extract of Mirabilis jalapa reducing besides immobilizing agent. The attribute of copper nanoparticles was studied by using UV-VIS spectroscopy SEM and XRD. The XRD spectrum of the copper nanoparticles established the presence of elemental …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 3, 2025 · pp. 56–65 Read article
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Pharmaceutical Cocrystals of Pain Relieving Drugs
Abstract: Cocrystallisation of two components into one crystal form can enhance the solid-state properties of drug compounds. Cocrystals are considered as the next generation modified-active pharmaceutical ingredients with improved physical-chemical, (aqueous solubility, dissolution, hygroscopicity, bioavailability, stability, increase of melting point, purity of an active pharmaceutical ingredients (API), intellectual property positions) and pharmacokinetic properties. Cocrystal formation may overcome dissolution problems of highly lipophilic APIs because the new crystalline lattice being formed often …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 1, 2015 · pp. 16–27 Read article
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Solanum viarum Dunal: Ethnomedicinal Importance, Phytochemical Profile and Pharmacological Potential — A Comprehensive Review
Abstract: Solanum viarum Dunal, commonly known as tropical soda apple or Sodom apple, is a medicinally important plant belonging to the family Solanaceae. The plant has been widely utilized in traditional medicine systems for the treatment of fever, cough, skin disorders, inflammation, gastrointestinal ailments, and microbial infections. The present review comprehensively summarizes the ethnomedicinal importance, phytochemical profile, pharmacological activities, and pharmaceutical significance of S. viarum. Literature reports indicate that the plant …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 3, 2026 Read article
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AI Enabled Pharma Supply Chain Market
Abstract: Pharmaceutical supply chains are changing because of artificial intelligence (AI). The pharmaceutical industry has always had to deal with uncertainty. From the start of research to the final delivery of medicines to patients, it faces scientific risks, government rules, and supply chain problems. In recent years, these challenges have gotten worse because there is more drug shortage, political issues are messing up transportation, and regulators are asking for more openness …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 Read article
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A Research on the Additives and Regulatory Requirements for Pediatric Formulation
Abstract: These days, pediatric considerations are incorporated early on in the creation of new medications. The guidelines and policies of European drug regulatory bodies served as the foundation for our investigation. The review comprehensively outlines excipients commonly found in pediatric medicine formulations. It identifies potentially harmful compounds flagged by scientific literature, stressing the necessity of rigorous safety checks, often involving toxicity studies. Excipients included in pediatric databases, like the STEP database, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 28–45 Read article
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A Review on Biotechnological Aspects of Conservation and Enhancements of Indian Snakeroot (Rauwolfia serpentina)
Abstract: Indian snakeroot (Rauwolfia serpentina) is one of the most important medicinal plants found in the Indian subcontinent, used in the treatment of various types of diseases. Recently it has been considered as a critically endangered plant by the International Union of the Conservation of Nature and Natural Resources (IUCN) due to its heavy exploitation in the past. The plant has a high demand in the international market due to its …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 9, Issue 2, 2022 · pp. 30–38 Read article
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Elemental Impurities: A Review
Abstract: The ICH Q3D is an important guideline to harmonize control of elemental impurities. The guideline sets strict limits for final drug products, limits for excipients, active pharmaceutical ingredients and other pharmaceutical drug products. The analysis of elemental impurities in the pharmaceutical products is most important in pharmaceutical industries. In the last decade noteworthy progress has been made in the analysis of elemental impurities. The changes from using special reagents which …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 1, 2020 · pp. 17–21 Read article
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Active versus Passive Microbiological Air Sampling Risk Assessment: Relation and Comparative Study in Pharmaceutical Industry
Abstract: Microbiological environmental monitoring of pharmaceutical manufacturing area is an essential task for control of the quality during medicinal dosage forms production. However, thorough scientific approach is critical to elucidate the full potential of microbiological test results and its significance. In the present study, 205 passive and 451 active air samples were withdrawn during course of ten months from air in class C production facility, dedicated for manufacturing of liquid and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 7, Issue 1, 2016 · pp. 13–27 Read article
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Potential Application of Retama sphaerocarpa Plant in Pharmaceuticals
Abstract: The aim of this study was to evaluate the phytochemical and biological activity (antibacterial and antifungal) of Retama sphaerocarpa plant and the possibility to use it in pharmaceutical formulations. This plant is traditionally used only as healing remedies because of their antiseptic, antipyretic and antidiarrheal properties. Phytochemical screening of leaves and stems revealed the presence of flavonoids, alkaloids, tannins and steroids. The antimicrobial activity was determined on bacterial strains such …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 3, 2019 · pp. 22–28 Read article
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Synthesis and Characterization of Polymer-Based Benzamide Derivatives with Potential Biomedical Applications
Abstract: The present study explores the synthesis and characterization of polymer-supported benzamide derivatives, focusing on their potential biomedical applications. The use of polymer-supported synthesis offers several advantages, including improved reaction efficiency, ease of purification, and reusability of the support material, making it an environmentally friendly and cost-effective approach. The synthesis involved a stepwise reaction sequence, with polymeric supports facilitating controlled functionalization and ensuring high product purity. These materials have been widely …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 Read article
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Metal Complexes of Cephalexin and Their Biological Activities: A Review
Abstract: Cephalexin and its derivatives are commonly utilized in the pharmaceutical and medicinal industry due to their biological and pharmaceutical activities, including anti-microbial, anti-cancer, anti-bacterial, and herbicidal activities as well as possessing high palatability and being useful for skin and joint infections. Interestingly, some organic drugs, including cephalexin, which exhibit toxicological and pharmacological properties, can be administered in forms of metal complexes. Many researchers have synthesized organic ligands derived from cephalexin …
Published in Journal of Polymer & Composites · Vol. 11, Issue 2, 2023 · pp. 52–61 Read article
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A Review of Analytical Method Development and Validation of Amiodarone Pharmaceutical Dosage Form
Abstract: The review provides an in-depth analysis of the analytical method development and validation process for amiodarone tablets. Method validation is crucial in the pharmaceutical industry for ensuring the quality and efficacy of tablets, as it ensures the accuracy, precision, and reliability of analytical techniques used in drug testing. It is a prerequisite for method development, adhering to good manufacturing practices, and optimizing processes. This review aims to consolidate and analyse …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 59–71 Read article
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Polymer Composite-Assisted Crystal Engineering for Drug Synthesis and Property Control through Solid Solutions and Co-Crystals
Abstract: The long-standing problem of low aqueous solubility, which affects about 90% of all new drug molecules under development, requires an immediate need for alternative approaches apart from the usual practice of crystallization. Polymer-composite-assisted crystal engineering is a novel technique for overcoming the aforementioned problem. This involves the addition of accepted pharmaceutical polymers, such as HPMC, PVP, PEG, and Eudragit copolymers in a single process, which can promote nucleation, stabilize the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 172–189 Read article
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Quality Control and Assurance Practices in Modern Pharmaceutical Industry
Abstract: This brief overview outlines the global techniques for figuring out the prevalence of geotaxis impurities (residual solvents and various inorganic and organic impurities) in medications. It is now necessary to reveal a pharmaceutical product's purity and impurity profiles due to both national and international regulations. These elements are discussed, together with the kinds of impurities, their origins, their control, and regulatory issues, as well as the significance of pharmaceutical quality, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 3, 2025 · pp. 07–13 Read article
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Polymer-Based Film Coatings for Enhancing Drug Stability and Shelf-Life
Abstract: Pharmaceutical stability is a crucial factor in ensuring drug efficacy and safety throughout its shelf-life. Polymer-based film coatings have emerged as an effective strategy to enhance drug stability by protecting active pharmaceutical ingredients (APIs) from environmental stressors such as moisture, oxygen, temperature fluctuations, and light exposure. These coatings act as physical barriers that prevent degradation, improve mechanical integrity, and enable controlled drug release. Various types of polymers are employed for …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 558–570 Read article
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Pharmaceutical Bead Formulations: A Comprehensive Overview into Advanced Drug Delivery
Abstract: Pharmaceutical beads are a unique and flexible drug delivery vehicle that provides numerous possibilities to control the release of drugs, protect them, and increase their therapeutic performance. These beads make it possible to design several types of therapeutic regimens by incorporating active pharmaceutical ingredients in a polymeric or lipid matrix. This review discusses the bead technology in drug delivery from its inception to its present application, focusing on the most …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 78–100 Read article
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Polymeric Materials in Drug Delivery: Applications in Topical Formulations
Abstract: Polymeric materials play a crucial role in modern drug delivery systems, particularly in topical formulations. These materials enhance drug stability, control release rates, and improve bioavailability, making them essential components in pharmaceutical advancements. Polymers such as chitosan, hydrogels, and emulsifying agents are widely utilized in immediate-release topical formulations, where they contribute to improving therapeutic efficacy by ensuring uniform drug distribution, increased solubility, and enhanced skin penetration. The integration of polymer-based …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 34–41 Read article
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Formulation Development and Evaluation Technique for Immediate and Modified Release Capsule
Abstract: The development and evaluation of formulations for immediate-release (IR) and modified-release (MR) capsules represent a critical aspect of pharmaceutical dosage form design, offering distinct advantages in terms of drug release profiles and therapeutic outcomes. This study focuses on the formulation strategies, techniques, and evaluation methods used to develop both IR and MR capsules. Immediate-release capsules are designed to disintegrate quickly in the gastrointestinal tract, ensuring rapid drug absorption, while modified-release …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 1–9 Read article
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Development and Validation of a Gradient RP-HPLC Method for Quantitative Determination of Potential Manufacturing Impurities in New Drug Apronalide and Pharmaceutical Formulations
Abstract: Three impurities in apronalide drug substance were detected and quantified using a simple isocratic reverse phase HPLC method. The chromatographic separation was achieved on a Thermo Hypersil gold-CN, 100 A0 5 µm, and 250X4.6 mm using a mobile phase consisting of phosphate buffer (pH-4.6) - Methanol with UV detection at 210 nm and flow rate of 0.8 ml/min. The column temperature was maintained at 250C throughout the analysis. This method …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 1, Issue 1, 2014 · pp. 1–10 Read article
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A Brief Review on Herbal Excipients
Abstract: Natural or herbal excipients are significantly more advantageous than their synthetic equivalents because they are readily available, non-toxic, and less expensive. The pharmaceutical industries are becoming more interested in using these herbal excipients – mainly polymers of natural origin – in formulation development because of growing knowledge of them. The purpose of this study is to provide light on the possibility of using natural excipients, which are biocompatible and able …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 2, 2025 · pp. 5–14 Read article