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3 articles for “Pharma 4.0”
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Panoramic review on Sida rhombifolia L.
Abstract: Sida Rhombifolia is also called Bala and is a well-known Ayurvedic herbal preparation used to treat inflammation, pain and neurological disorders. Literature calls Bala as Sida cordifolia, Sida, root powder acute, Sida cordata or Sida Rhombifolia subsp. retusa to achieve clinical efficacy of standardization of ksheerBala thailam Balamulacherna is essential.The objective of the study is to authenticate the pharmacognostic standards of Sida Rhombifolia root powder. Sida Rhombifolia was standardized with …
Published in International Journal of Pathogens · Vol. 1, Issue 1, 2024 · pp. 20–32 Read article
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Pharmacophore mapping, 3D QSAR, docking, and ADME prediction studies of novel Benzothiazinone derivatives
Abstract: Background Tuberculosis is a major public health concern worldwide which is caused by Mycobacterium tuberculosis. DprE1 (Decaprenyl Phosphoryl Ribose 2’- Epimerase) is the most challenging target for development of novel anti- tubercular agents because it is a small protein and located into cytoplasmic membrane. So, novel anti-TB drugs did not bound effectively with it. DprE1 catalyzes the oxidation of the 2’ hydroxyl group of DPR (Decaprenyl Phosphoryl D- Ribose) …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 59–82 Read article
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Zolmitriptan Mouth Dissolving Tablets: Development of Formulas and Invitro Evaluation
Abstract: Pharma Burst ODT super disintegrants were used in different concentrations to manufacture Zolmitriptan fast dissolving tablets by a direct compression method. With a 28° angle of repose, there is good flow. The densities for bulk and tapped materials are 0.410 (g/ml) and 0.500 (g/ml), respectively. The compressibility index and Hausner ratio have values of 19.05 and 1.24, correspondingly. According to IP standard, weight variation test results range from 121.4 mg …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 1–15 Read article