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25 articles for “Oxidative stress”
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Neuroinflammation Is Aggravated by the Aqueous Extract of Myrmecodia Platytyrea Tuber
Abstract: Myrmecodia platytyrea, commonly known as the ant plant, is a medicinal epiphyte traditionally used in Southeast Asia for its purported health benefits, including anti-inflammatory, antioxidant, antimicrobial, and anticancer activities. Its tuber contains abundant secondary metabolites, including flavonoids, tannins, phenolic compounds, and saponins. While these phytochemicals are generally associated with therapeutic effects, the biological activity of Myrmecodia extracts varies depending on the type of extract, dosage, and route of administration. In …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 5–14 Read article
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Circadian Regulation of Lipid Peroxidation in the Brain: Linking Ferroptosis to Neurodegenerative Vulnerability
Abstract: The human brain operates through highly coordinated physiological and biochemical processes that regulate cognition, behavior, and neural adaptability. Central to these processes are mechanisms governing brain function, neurophysiology, and neuroplasticity, which are increasingly recognized to be influenced by circadian rhythms. Recent advances in cognitive neuroscience, neuroimaging, and behavioral neuroscience have revealed that disruptions in circadian regulation can significantly impact oxidative balance within the brain, particularly through enhanced lipid peroxidation. Lipid …
Published in International Journal of Brain Sciences · Vol. 3, Issue 2, 2026 · pp. 1–14 Read article
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Nutrient-Mediated Activation of Cellular Signaling Pathways: Mechanistic Insights into Attenuation of Toxin Induced Inflammation in Food Animals
Abstract: Dietary and environmental toxins remain a persistent challenge in food animal production, where subclinical and clinical inflammation compromises health, productivity, and food safety. Toxin induced inflammation is driven by oxidative stress, mitochondrial dysfunction, and dysregulated immune signaling, resulting in impaired metabolic efficiency and increased disease susceptibility. Recent advances in nutritional science have revealed that nutrients act not only as substrates for growth but also as signaling molecules capable of modulating …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 1–12 Read article
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Role of Centella asiatica in Alzheimer’s Disease: A Comprehensive Review
Abstract: Alzheimer's disease (AD) is a progressive neurological illness that causes cognitive decline and memory loss and affects millions of people worldwide. As synthetic medications often prove ineffective or cause severe side effects, natural remedies are gaining attention. This review explores the potential of Centella asiatica, a herb traditionally used in oriental medicine, in the treatment of Alzheimer's disease. Triterpenoids, asiaticoside, and madecassoside are among the bioactive substances found in Centella …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
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Exploring the Therapeutic Potential of Phytohormones: Bridging Plant Immunity and Human Health
Abstract: This review highlights the multifaceted roles of phytohormones, including salicylic acid, abscisic acid, cytokinins, and brassinosteroids, emphasizing their contributions to plant immunity and potential therapeutic applications in human health. Phytohormones are critical regulators of plant growth, development, and defense, functioning as signaling molecules that activate and coordinate plant responses to biotic and abiotic stresses. Salicylic acid, in particular, is instrumental in systemic acquired resistance (SAR), a defense mechanism that strengthens …
Published in International Journal of Trends in Horticulture · Vol. 1, Issue 2, 2024 · pp. 20–23 Read article
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Tobacco and COVID-19: Molecular Interactions and Public Health Challenges – A Review
Abstract: Tobacco use exacerbates health risks, making it a significant concern during the COVID-19 pandemic. Smoking has been implicated in the upregulation of ACE2 receptors, critical for SARS- CoV-2 entry, and contributes to immune dysregulation and oxidative stress, worsening clinical outcomes. Methods: This review synthesizes evidence on the molecular mechanisms linking tobacco and COVID-19, assesses risk factors, such as smoking status and comorbidities, and explores public health challenges in managing the …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 1–6 Read article
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Review on Ferulic Acid in Cosmaceuticals
Abstract: Ferulic acid is low in toxicity and possesses a variety of physiological qualities, including anti- inflammatory, antioxidant, antibacterial, anticancer, and antidiabetic effects. Science has demonstrated that ferulic acid, a potent antioxidant, has beneficial benefits on skin care. In addition to preventing pigmentation and whitening the skin, ferulic acid also prevents acne. Ferulic acid which is a strong natural antioxidant is necessary in protecting the skin against oxidative stress caused by …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 1, 2026 · pp. 13–20 Read article
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Histological Effects of the Antibiotic Gentamicin on the Ovarian Tissue of Female White Laboratory Rats
Abstract: This study aimed to evaluate the histological alterations induced by Gentamicin in the ovarian tissue of white laboratory rats. A total of 12 adult female rats were used and randomly divided into two groups, with each group consisting of six animals. The experimental group received Gentamicin at a dose of 120 mg/kg body weight administered as an injection once daily, while the control group received an equivalent volume of normal …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 1–8 Read article
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Exploring the properties and extraction of neem leaves
Abstract: Neem (Azadirachta indica) is a versatile medicinal plant, for its diverse therapeutic properties. This abstract provides a comprehensive overview of recent research focusing on phytochemical analysis, biochemical characterization, and antimicrobial susceptibility testing of Neem extracts. Utilizing the different from of chemical used in it, phytochemical analysis identified a plethora of secondary metabolites within Neem, including alkaloids, flavonoids, terpenoids, steroids, saponin, tannins, quinone, and phenolic compounds, indicative of its complex chemical …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 32–39 Read article
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Comparative Analysis of Bioactive Phytochemical Profiles of Moringa Oleifera and Aegle Marmelos Grown in Bundelkhand
Abstract: A comparative analysis of the bioactive phytochemical profiles of Moringa oleifera and Aegle marmelos grown in the Bundelkhand region was conducted to explore their potential health benefits. These properties make healing plants valuable in herbal medicine, supporting various aspects of health and well-being. The study aimed to determine the differences in the concentrations of bioactive compounds such as phenolic, flavonoids, alkaloids, and vitamins C and E in the leaves and …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 14–24 Read article
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Flaxseed and Diabetes Management: A Comprehensive Review of Recent Studies and Potential Mechanisms
Abstract: Diabetes mellitus, a condition characterized by chronic hyperglycemia, has become a significant global health challenge, leading to substantial morbidity and mortality rates. Dietary techniques are crucial for the effective control of diabetes, including both pharmaceutical and non-pharmacological therapies. Flaxseed (Linum usitatissimum) is one of the functional foods that has attracted a lot of interest because of its abundance of bioactive components, including lignans, dietary fiber, and alpha-linolenic acid (ALA). The …
Published in International Journal of Nutritions · Vol. 2, Issue 1, 2025 · pp. 24–32 Read article
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Turmeric as a Key Ingredient in Cosmeceuticals: New Scientific Evidence
Abstract: Turmeric (Curcuma longa), particularly its active compound curcumin, is gaining recognition in cosmetics and medicine for its therapeutic properties. Its antioxidant, anti-inflammatory, and antimicrobial effects make it a popular skincare ingredient, helping reduce inflammation, brighten skin, and fight aging. In addition to treating dandruff and promoting hair growth, Turmeric is also good for scalp health. Curcumin increases the body's antioxidant defenses. Inhibits inflammation and anti-oxidants. Curcumin, a powerful compound found …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 1, 2025 · pp. 28–36 Read article
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Rosemary: A Natural Way to Improve Brain Health and Cognitive Function
Abstract: Cognitive decline is a common consequence of aging, often leading to diminished quality of life. Although conventional drug treatments, such as anticholinesterase inhibitors, are available for managing cognitive decline, they are not always effective in older adults and may even induce adverse effects. As a result, there has been growing interest in natural alternatives, particularly traditional herbal medicines, for their potential cognitive-enhancing properties. Among these, Rosmarinus officinalis (Rosemary) has gained …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 30–36 Read article
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A Comprehensive Review on Neturaceuticals in Alzheimer's and Neurodegenerative Disease an Cognitive Enhancement
Abstract: Neurodegenerative diseases, including Alzheimers disease (AD), Parkinsons disease (PD), and related cognitive disorders, represent a significant and growing public health challenge, particularly in aging populations. Despite advances in pharmacological treatments, therapeutic options for cognitive decline and neurodegeneration remain limited. Recent interest has shifted towards nutraceuticals— bioactive compounds derived from food or natural sources—as promising adjuncts or alternatives in the management of these conditions. This review examines how nutraceuticals can help …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 1–9 Read article
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Study on Chemical Insights into Alzheimer's Disease: Amyloid Beta and Tau Protein Interactions
Abstract: Background: Alzheimers disease (AD) is the most prevalent form of dementia, affecting millions of individuals worldwide and posing significant challenges to healthcare systems. The disease is characterized by a gradual decline in cognitive functions, particularly memory, reasoning, and the ability to perform daily activities. Aim & objective: To study chemical insights in alzheimers disease, especially amyloid beta and tau protein interactions Results & discussion: The results of this review highlight …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 37–46 Read article
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Rapid Post-uterine Involution in Dairy Cows: Mechanisms, Dietary Strategies, and Impact on Postpartum Recovery
Abstract: The postpartum period in dairy cows is critical for reproductive success, with uterine involution playing a central role in returning the reproductive tract to its pre-pregnancy state. Rapid uterine involution is essential for improving reproductive performance and minimizing the risk of postpartum complications. This review explores the nutritional mechanisms that influence uterine involution, focusing on key dietary strategies to promote tissue repair and recovery. We examine the role of energy, …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article
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Samelisant, an H3 Receptor Agonist as an Anti-Alzheimer Potential – A Pilot Study on Molecular Docking
Abstract: Neurodegenerative diseases have become more prevalent and about 55 million of the population are affected by dementia globally. One of the most important neurodegenerative diseases is Alzheimer’s disease which is known for its effect on memory and cognitive impairment. Alzheimer’s disease (AD) is an area of intense scientific investigation due to its high prevalence and the lack of a definitive cure. Amyloid precursor protein plays a central role in Alzheimer’s …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 15–26 Read article
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Biological Membranes: Structure, Function, and Their Roles in Disease Pathophysiology
Abstract: Biological membranes are important structures that control cellular work, signal transmission, transport, and communication. Dysfunction of membranes has been considered in the development of many diseases, such as cancer, neurodegenerative diseases, and infections, with the distortion of lipid composition, protein activity, and cellular connections involved in the pathogenesis of the disease. The damage on membrane can be caused by oxidative stress, genetic mutation, and environmental influence to disrupt cellular homeostasis. …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 38–46 Read article
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Nature’s Pharmacy: Plant-Based Antifungal Agents and Their Therapeutic Potential
Abstract: Antifungal resistance has increased dramatically over the last 10 years, causing serious problems for healthcare because of higher morbidity and death. The urgent need for new treatments is highlighted by the scarcity of effective antifungal medications, their toxicity, and the rise of resistant strains. Since many plants have bioactive secondary metabolites with strong antifungal qualities, including alkaloids, flavonoids, terpenoids, phenolics, and saponins, ethnobotanical sources offer a viable path. Plants with …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 1–7 Read article
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Emerging Trends in Horticultural Crops: Role of Date Fruit in Promoting Urinary and Kidney Health
Abstract: Dates, or Phoenix dactylifera L., have been widely consumed in different cultures, both as a food source and for their health benefits. Whereas dates have been reported extensively to improve cardiovascular, gastrointestinal, and metabolic function, their role in urinary tract and renal health has received lesser attention in mainstream nutritional sciences. This review systematically evaluates and synthesizes the current literature on the potential effects of dates to promote urinary health …
Published in International Journal of Trends in Horticulture · Vol. 3, Issue 1, 2026 · pp. 24–32 Read article