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173 articles for “Nano Formulation”
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Development of an Innovative Nanotransdermal Formulation Utilizing an Optimal Combination of Acyclovir and Omeprazole to Improve Antiviral Efficacy
Abstract: The study effectively created nanogel formulations of Acyclovir and Omeprazole using the solvent diffusion technique. Among the various formulations (F1–F9), F9 was identified as the most suitable for gel preparation based on its pH evaluation. Drug content analysis, performed using UV-spectroscopy, confirmed the homogeneity of the prepared nanogels, which appeared opaque, free of lumps, particles, or aggregates. The spreadability assessment of F9 demonstrated excellent spreadability, while viscosity values for all …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 19–35 Read article
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Use of Nano-Formulated Ayurvedic Medicines: A Bridge Between Tradition and Modern Science in South India
Abstract: The integration of nanotechnology with traditional Ayurvedic medicine represents an exciting and emerging area of healthcare innovation. By combining the age-old wisdom of Ayurveda with the precision and efficiency of modern nanotechnology, researchers are developing new ways to enhance the effectiveness of herbal treatments. Nanotechnology allows for the creation of tiny drug delivery systems that can improve how Ayurvedic medicines are absorbed and utilized in the body, potentially making them …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 3, 2025 Read article
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Comprehensive Evaluation of Quercetin from Bauhinia purpurea for Its Anti-Acne and Anti-Inflammatory Potential, Including Advances in Quercetin-Loaded Nanogel Formulation
Abstract: Acne vulgaris is among the most prevalent chronic inflammatory dermatoses in clinical dermatology, afflicting a substantial proportion of the global adolescent and adult population. Conventional pharmacotherapies — including topical retinoids, benzoyl peroxide, and systemic antibiotics — remain the therapeutic mainstay; however, their long-term utility is progressively undermined by adverse cutaneous reactions, systemic toxicity, and the rising prevalence of antibiotic-resistant Cutibacterium acnes strains. These limitations have intensified scientific interest in plant-derived …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 2, 2026 · pp. 34–46 Read article
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Iota carrageenan, a Sustainable polymer transformed into a nanogel formulation, by using environment friendly method for antitumor action
Abstract: In the pharmaceutical field, the utilization of polymers, both in their natural form and through chemical modifications, holds immense importance. In this context, a novel and eco-friendly method for the synthesis of nano carrageenan-based polymers has been developed. The efficacy of carrageenan in this domain is attributed to its crosslinking and biological properties, which are largely influenced by its sulfate ion content. This study aims to formulate nanogels via a …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 881–889 Read article
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HERB BASED NANO-FORMULATIONS USED AS ANTI-INFLAMMATORY ACTIVITY
Abstract: It plays a crucial role in the progression of various ailments such as gastric inflammation, atherosclerosis, rheumatoid arthritis, asthma, and cancer.The lack of antibodies and transporters leads to the need to create molecules for the treatment of inflammatory diseases. Nanometer technology has become an exciting area of research over the past decade as its performance outperforms many of its products. This article discusses the green synthesis of zinc oxide nanoparticles …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 14, Issue 1, 2023 · pp. 42–52 Read article
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Comprehensive account on role of catechin based polyphenols in nanocomposite formulations
Abstract: Antioxidants play a crucial role in wellness, health maintenance and the prevention of chronic and degenerative disease, in neuroprotection activities and protection against oxidative cellular damage by U.V. radiation. Polyphenols are secondary metabolites of plants usually involved in defense against ultraviolet radiation or aggression by pathogens. Antioxidant properties, free radical-scavenging abilities and antimicrobial properties of these polyphenols make them useful in the field of biomedical applications, used as food additives, …
Published in Journal of Polymer & Composites · Vol. 8, Issue 1, 2020 · pp. 26–31 Read article
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Formulation And Evaluation Of Itraconazole Loaded Solid Lipid Nanoparticles For Tinea Cruris:A Promising Approach To Combat Antifungal Drug Resistance
Abstract: A fungal infection of the skin is among the most prevalent dermatological conditions worldwide. When used topically, gel formulations are among the best dose forms for treating skin infections. A promising method to reach the deeper layers of the skin and improve itraconazole (ITZ) permeability through the stratum corneum is nanotechnology. The production of ITZ-loaded nanoparticles (ITZ NPs) was accomplished through the evaporation emulsion method, and subsequently, these nanoparticles were …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 10, Issue 3, 2023 · pp. 22–28 Read article
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Biomedical Approach to Developing and Characterizing Chitosan Nanoparticles Encapsulating Urapidil for Hypertension Management
Abstract: The aim of this study was to create Chitosan Nanoparticles loaded with Urapidil to achieve controlled drug release, enhance solubility, and reduce dosing frequency to improve patient adherence to therapy for hypertension. Urapidil was formulated into nanoparticles via the ionic-gelation method using Chitosan as a polymer, Sodium tripolyphosphate as a cross-linking agent, and filled into hard gelatin capsules after lyophilization. Pre-formulation studies, including melting point analysis and determination of the …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 43–51 Read article
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Innovative Approaches in Pediatric Drug Formulation Catering to Specialized Need: Review Article
Abstract: This detailed article review examines innovations in pediatric drug formulation, highlighting developments that cater to children’s specific healthcare needs. It covers pediatric pharmacology and advanced solutions like nanoparticle drug delivery and taste-making techniques, focusing on improving the safety, effectiveness, and acceptability of medications for young patients. The review highlights the benefits for patients, including improved adherence to treatment, fewer side effects, and better overall treatment outcomes. It also addresses regulatory …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 35–43 Read article
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Formulation and development of Lamivudine Nanoemulsion by using Emulsifying Polymers and It’s Evaluation
Abstract: Nanoemulsion is a novel approach to medicine delivery that helps to increase the bioavailability of drugs that aren’t particularly soluble in water. In this research work, nanoemulsion of Lamivudine was formulated by using polymers such as SPAN 80, TWEEN 80 and Whey protein concentrate with the help of Ultrasonication technology. The formulation was optimized. It was evaluated by assessing pH, viscosity, turbidity, in vitro franz diffusion study, particle size distribution, …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 22–35 Read article
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Solid Lipid Nanoparticles in Medicine: Formulation, Characterization and Future prospects
Abstract: An alternative to conventional colloidal carriers such liposomes, polymeric nanoparticles, and emulsions, solid lipid nanoparticles (SLNs) were created in the early 1990s. Benefits include targeted medicine distribution, controlled drug release, and improved stability. An extensive review of the excipients utilized, the production techniques, including the membrane contractor approach, and the possible advantages and disadvantages of SLNs is given in this work. It investigates secondary stabilization techniques like freeze-drying and spray-drying, …
Published in International Journal of Membranes · Vol. 2, Issue 1, 2025 · pp. 1–15 Read article
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Nano-Materials in Vaccine Formation and Chemical Formulae’s for Vaccination
Abstract: For centuries, vaccines have been a cornerstone of public health, preventing debilitating and deadly diseases. However, the development and delivery of effective vaccines have always been met with challenges. From stability issues and limited immune response to the need for specific targeting, scientists are constantly seeking innovative approaches to improve vaccine efficacy and accessibility. Enter nanomaterials – minuscule materials with dimensions at the nanoscale – offering a powerful toolkit to …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 3, 2025 · pp. 27–39 Read article
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Enhanced Oil Recovery through the Application of Nanoparticles with Irvingia Gabonensis in Flooding Process in the Reservoir
Abstract: This experimental investigation is aimed at establishing the ability of nanofluids formula from a mixture of nanoparticles and oil extracted from Irvingia gabonensis (bush mango) in enhancing recovery from oil reservoir. The laboratory study involved the use of core flooding unit, crude oil, brine, nano-particles and Irvingia gabonensis. In this study, nanofluids formulated from nanoparticles of aluminum oxide (Al 2 O 3 ) and zinc oxide (ZnO) respectively were used …
Published in Journal of Petroleum Engineering & Technology · Vol. 12, Issue 2, 2022 · pp. 1–9 Read article
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Formulation and Characterization of Mesoporous Nanoparticulate Drug Delivery Platform
Abstract: The aim of this study was to synthesize and characterize mesoporous silica nanoparticles, namely, SBA-15 (Santa Barbara Amorphous) and MCM-41 (Mobile Crystalline Material) as a drug delivery platform. These MSNs have been synthesized using triblock copolymer F 127, cetyl trimethyl ammonium bromide (CTAB) as a co-surfactant and tetraethyl orthosilicate (TEOS) as a silica precursor. The synthesized MSNs were characterized by scanning electron microscopy (SEM), powder X-ray diffraction (PXRD), particle size …
Published in Trends in Drug Delivery · Vol. 2, Issue 1, 2015 · pp. 21–27 Read article
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Formulation and Evaluation of Solid Lipid Nanoparticles of BCS Class II Drug
Abstract: In the present study, we explored the potential of antihypertensive drug loaded solid lipid nanoparticles (SLNs), as a new formulation in improving the oral bioavailability of drug, which otherwise reported with poor bioavailability. The problem of poor water-solubility has remained as a significant challenge in pharmaceutical industry. The reduction of drug particle to the nano-level increases the surface area and improves solubility and dissolution of drug and proportionate increase in …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 6, Issue 2, 2019 · pp. 32–54 Read article
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A Comprehensive Analysis of Novel Liposomes: Categorization, Approach, Description, and Present Formulations
Abstract: Liposomes have gained attention as a promising drug delivery system, which come with the advantages of biocompatibility, ability to load hydrophilic and hydrophobic drugs, and they can function for targeted drug delivery. In this regard, this paper offers a comprehensive overview on novel liposomes, including classification, formulation strategies, detailed structures, and current pharmaceutical applications. Recent advances in liposomal drug delivery systems includes, new liposomal architectures (i.e. stealth, targeted, stimuli-responsive, hybrid …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 15–20 Read article
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Exploring Type-II Diabetes Potential of Phyto-Derived Carbon Dots
Abstract: The integration of phytoconstituents with carbon dots (C-dots) presents a novel and sustainable approach to the development of nanotherapeutics for type 2 diabetes mellitus (T2DM). C-dots, zero-dimensional carbon-based nanomaterials, exhibit unique physicochemical properties including high fluorescence, tunable surface chemistry, biocompatibility, and low toxicity. Their ability to enhance the solubility, bioavailability, and targeted delivery of poorly soluble phytochemicals renders them highly suitable for biomedical applications. This study explores the synthesis of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 08–25 Read article
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Phyto-Entrapped Carbon Dots as Emerging Nanomaterials for Anti-Cancer Activity
Abstract: Phytoconstituent-loaded carbon dots (C-dots) represent an innovative approach in targeted cancer therapy, combining the therapeutic power of plant-derived compounds with the advanced capabilities of nanotechnology. These ultra-small, biocompatible nanostructures offer excellent fluorescence, tunable surface chemistry, and low toxicity, making them ideal for drug delivery, bioimaging, and theranostic applications. Traditional phytochemicals often face challenges like poor solubility, low bioavailability, and high first-pass metabolism barriers that C-dots help overcome. C-dots synthesized through …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 51–63 Read article
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Synthesis and Characterization of PF-127 Stabilized Metformin Encapsulated Chitosan-TPP Nanoparticles
Abstract: Metformin is widely used to manage Type 2 Diabetes, but its effectiveness is limited by low intestinal absorption, high dose requirements, and a short half-life. To tackle these challenges, several nano-drug delivery systems have been designed to optimize the delivery of metformin and enhance its therapeutic efficacy. Nanoparticles (NPs) have emerged as key players in medicine, biology, and pharmacology, gaini considerable attention for their potential applications. Polymeric NPs are among …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 1, 2025 · pp. 34–38 Read article
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Ocular Drug Delivery System: Challenges and Opportunities
Abstract: Eye is most sensitive organ of body which is highly protected to prevent entry of any exogenous substance. This defence mechanism of eye renders the development of ocular drug delivery system as the challenging task to ophthalmic formulation scientist. Knowledge of anatomy, physiology and barriers for transportation of drug at different target site of eye is essential to develop successful ocular formulation. Topical administration of drug in the form of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 9, Issue 3, 2018 · pp. 14–30 Read article