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15 articles for “Modified release”
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Formulation Development and Evaluation Technique for Immediate and Modified Release Capsule
Abstract: The development and evaluation of formulations for immediate-release (IR) and modified-release (MR) capsules represent a critical aspect of pharmaceutical dosage form design, offering distinct advantages in terms of drug release profiles and therapeutic outcomes. This study focuses on the formulation strategies, techniques, and evaluation methods used to develop both IR and MR capsules. Immediate-release capsules are designed to disintegrate quickly in the gastrointestinal tract, ensuring rapid drug absorption, while modified-release …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 1–9 Read article
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Pharmaceutical Bead Formulations: A Comprehensive Overview into Advanced Drug Delivery
Abstract: Pharmaceutical beads are a unique and flexible drug delivery vehicle that provides numerous possibilities to control the release of drugs, protect them, and increase their therapeutic performance. These beads make it possible to design several types of therapeutic regimens by incorporating active pharmaceutical ingredients in a polymeric or lipid matrix. This review discusses the bead technology in drug delivery from its inception to its present application, focusing on the most …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 78–100 Read article
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Advances in Biodegradable Polymer-based Drug Delivery Systems
Abstract: An intriguing new approach to manage medication release that may assist with issues like making the therapeutic impact last longer, reducing the danger of side effects, and persuading patients to follow through with their treatment programs is biodegradable polymer-based drug delivery systems (DDS). By developing systems that can break down within the body, biodegradable polymers have revolutionised the way medications are administered. They so have less negative effects and do …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 326–338 Read article
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Comprehensive Overview of Carbohydrate Polymers
Abstract: Targeting drug delivery specifically to the colon has become increasingly crucial for treating various colonic diseases like colorectal cancer, amebiasis, ulcerative colitis, and Crohn’s disease. Numerous strategies have been developed for this purpose, including using enzymatically degradable polymers, employing prodrug-based approaches, coating drugs with polymers sensitive to time or pH changes, utilizing osmotically and pressure-controlled delivery systems. Polysaccharides activated by the colon's physiological environment show significant potential as they offer …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 8–21 Read article
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ISGylation: A Key Host Cellular Defense Mechanism
Abstract: ISGylation, a crucial process of the innate immune response, has garnered increasing attention for its involvement in host's defense against pathogenic infections as well in cancer progression. The key player of ISGylation, ISG15, is stimulated by type I interferons (IFNs). ISG15 covalently binds with viral (influenza NS1A and nucleoproteins) and host (Nedd4, filamin B and CHMP5) target proteins and this interaction inhibits the viral replication process and release of viral …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 2, 2024 · pp. 68–80 Read article
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Influence of Polymeric Carriers on the pH-Modifying Properties of Intracanal Medicaments in Root Canal Treatment
Abstract: Calcium hydroxide (CH) preparations and medicated gutta-percha are widely used intracanal medicaments in root canal treatment. These materials often incorporate polymeric carriers to deliver the CH payload and influence its therapeutic effect. This in-vitro study investigates the impact of different polymeric carriers on the pH-modifying properties of intracanal medicaments within the root canal system. The research focuses on two key aspects: (1) the ability of the polymers to control the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 967–974 Read article
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A Brief Review on Herbal Excipients
Abstract: Natural or herbal excipients are significantly more advantageous than their synthetic equivalents because they are readily available, non-toxic, and less expensive. The pharmaceutical industries are becoming more interested in using these herbal excipients – mainly polymers of natural origin – in formulation development because of growing knowledge of them. The purpose of this study is to provide light on the possibility of using natural excipients, which are biocompatible and able …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 2, 2025 · pp. 5–14 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Sustainable Biomedical Applications
Abstract: Liposomal drug delivery has evolved into a viable approach in modern pharmacology thanks to its enhanced bioavailability, reduced systemic toxicity, and targeted drug release. Conventional liposomes have limited stability, medicine leakage, and short circulation times among other problems. Overcoming these limits, the inclusion of nano-polymers into liposomal formulations has transformed medication delivery. Thorough research has been done on the potential of nano-polymers including chitosan, hyaluronic acid, polyethylene glycol (PEG), and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 420–432 Read article
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Liposomes as Therapeutic Vehicles: Advancing Targeted Drug Delivery in Healthcare
Abstract: Liposomes represent an innovative approach to targeted drug delivery. These tiny, lipid-based vesicles can encapsulate medications, allowing them to travel directly to diseased cells while minimizing impact on healthy tissues. By using liposomes, medications can improve their effectiveness while reducing side effects, leading to better overall treatment results.. Their structure enables a controlled release of the drug, which can be particularly beneficial for therapies requiring sustained action. This technology holds …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 39–46 Read article
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Bioscouring And Anionization of Waste Cotton Fabric for Efficient Removal of Malachite Green Dye
Abstract: Adsorption is an efficient method for dye removal but the high cost of adsorbents limits its use, emphasizing the need for sustainable, low-cost alternatives. This study explores the usage of modified cotton fabric for the treatment of malachite green (cationic dye) from wastewater. Cellulase extracted from Raphanus sativus and Daucus carota were evaluated for bioscouring potential which was confirmed by scanning electron microscopy. Further, cotton fabric was chemically modified using …
Published in Journal of Water Pollution & Purification Research · Vol. 13, Issue 1, 2026 · pp. 53–68 Read article
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Biodegradable Polymer Nano Composites for Enhanced Drug Bioavailability
Abstract: Polymer-based nanoparticles have emerged as a revolutionary approach in drug delivery systems, particularly in enhancing the bioavailability of poorly soluble and unstable drugs. These nanoparticles, composed of both natural and synthetic polymers, serve as effective vehicles for encapsulating a wide range of therapeutic agents. Their surface characteristics can also be modified to enable targeted drug delivery, increasing the concentration of drugs at the site of action while minimizing side effects. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 433–443 Read article
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Exploring Recent Advancements in Nanomedicine for Tumor Microenvironmental Tissue Engineering
Abstract: The combination of tissue engineering and nanomedicine is transforming cancer treatment by offering creative ways to get around problems with conventional therapies. Recent developments in nanomedicine are examined in this review, with an emphasis on how they might be used to comprehend and control the tumor microenvironment (TME), a dynamic and complex environment that has a major impact on the course of cancer and the effectiveness of treatment. Targeted interactions …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 122–136 Read article
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A Review of the Role of Fiber Supplements in Digestive Health and Weight Management
Abstract: The essential component of a nutritious diet is dietary fiber which enables body weight regulation and maintains digestive system health. Several supplements derived from fiber have gained popularity during recent years since they help improve gut health while controlling weight and preventing metabolic diseases. The two major groups which make up fiber are soluble and insoluble fibers that impact the body differently. The soluble fiber components psyllium inulin and beta-glucans …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 24–35 Read article
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Performance, Emission, and Combustion Evaluation of Chlorella Vulgaris Biodiesel-Diesel Blends in a Compression Ignition Engine
Abstract: This study examines, without modifying the engine, the performance, emissions, and combustion properties of biodiesel blends made from Chlorella vulgaris microalgae in a four-stroke, single-cylinder, water-cooled CI engine. The blends of biodiesel and diesel, designated B10, B20, B30, and B40, were 10%, 20%, 30%, and 40%, respectively. Of these, B20 showed the best efficiency-to-emissions ratio. Although it recorded the lowest brake specific fuel consumption of 0.232 kg/kWh, indicating superior fuel …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 339–354 Read article
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Hydrolysis-Driven Optimization of Hydroxypropyl Maize Starch for Improved Micro-Pellet Binding and Quick Solubility of Spirulina-Based Micro-Pellets
Abstract: Acid hydrolysis is a well-established approach for modifying the physicochemical properties of polysaccharides & macromolecules including hydroxypropyl Maize starch (HPMS). In this study, the effect of varying concentrations of hydrochloric acid on the partial hydrolytic degradation of HPMS (Lycoat RS-780) was investigated at 85°C for 4 h, yielding polymers of different molecular weights. The Acid-mediated degradation effects on polymer characteristics were systematically assessed using capillary viscometry and gel permeation chromatography …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 3, 2026 Read article