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20 articles for “Liver Function Test”
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Observation of Liver Function Tests in Children with Acute Hepatitis
Abstract: Introduction: Hepatitis B is an infectious illness caused by hepatitis B virus (HBV) which infects the liver of hominoidea, including humans, and diagnosed by liver function tests (LFTs) and serologic tests. Aims: The present study was conducted to evaluate the prevalence of acute hepatitis caused by hepatitis B virus and observation of the LFTs for early diagnosis and severity of acute hepatitis. Material and Methods: The study was carried out …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 8, Issue 2, 2018 · pp. 42–45 Read article
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Survey of Liver Disease Prediction Using Machine Learning
Abstract: Liver disease is one of the major causes of death in all over world that impacts the number of people around the world. Diagnosis of liver at early stages is crucial to reduce morality. As technology is growing in health care, machine learning significantly affects health care for predicting conditions at early stages. This study reviews the different approaches based on machine learning and deep learning to predict liver disease. …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 10, Issue 1, 2023 · pp. 30–38 Read article
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Safety evaluation of Maghz-e-Jamun (Eugenia jambolana) in Prediabetes - A Randomized Placebo Controlled Study
Abstract: Objective: to evaluate the safety of Unani drug Maghz-e-Jamun(Eugenia jambolana) in Prediabetes. Research design and methods: It was randomized, single blind, placebo-controlled study randomly assigned to 52 prediabetic patients (diagnosed according to ADA classification) in the test and control group. Maghz-e-Jamun (Eugenia jambulana) powder 4.5 g was filled in 6 capsules, 3 capsules were administered orally twice a day in the test group for 12 weeks. While placebo prepared with …
Published in Research & Reviews : Journal of Herbal Science · Vol. 8, Issue 2, 2019 · pp. 19–27 Read article
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SGOT (Serum Glutamic Oxaloacetic Transaminase)—Its Role (A Review Article)
Abstract: Aspartate transaminase (AST) is an important liver enzyme which catalyses reversible transfer of an alpha amino group between aspartate and glutamate. It has an important role in amino acid metabolism. AST is predominantly found in the liver, skeletal muscle, kidneys, brain and red blood cells. AST is measured as a part of diagnostic liver function test, but AST reflects pathology in organs other than liver. Elevation in AST is found …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 3, 2019 · pp. 1–5 Read article
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Drug-Induced Liver Injury: Hepatotoxicity and Treatment - A Literature Review
Abstract: Drug-induced liver injury (DILI) is a major clinical and regulatory challenge, posing risks to patient safety and drug development worldwide. As the primary organ responsible for xenobiotic metabolism, the liver is particularly susceptible to toxic injury from prescription drugs, over-the-counter medications, herbal products, and dietary supplements. Drug-induced liver injury (DILI) accounts for a substantial proportion of acute liver failure cases and remains a leading cause of post-marketing drug withdrawal. Its …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 1, 2026 · pp. 1–17 Read article
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A Rare Cause of Parkinsonism—Manganese Toxicity
Abstract: A 43-year-old male presented with six months history of gradual onset and progressive bradykinesia, tremors of upper limbs and walking difficulty in the form of imbalance and short shuffling gait. He also had slurring of speech with hypophonia. Neurological examination revealed slow broken saccades, rigidity with cogwheeling, bradykinesia and short shuffling, festinant gait. He had action and postural tremors of upper limbs. Pull test was positive. Thus, a diagnosis of …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 9, Issue 1, 2019 · pp. 29–32 Read article
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Clinical Profile of Dengue Fever with Its Acute Complications in Rural Population of Jaipur District
Abstract: Dengue is the most important mosquito-borne viral infection in terms of morbidity and mortality. In recent years, it has become a major public health concern. The present study was conducted on hospitalized adult patients of NIMS Medical College & Hospital with the aim to study the clinical profile and usual presentations of dengue fever. During the study of 75 patients of dengue infection, 18 had dengue fever (DF), 19 had …
Published in Research and Reviews: A Journal of Medicine · Vol. 4, Issue 1, 2014 · pp. 12–23 Read article
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Evaluation of Safety of Unani Pharmacopieal Majoon-e-Lana in Cases of Neurasthenia
Abstract: Neurasthenia, referred to as Zof-e-Asaab in the Unani system of medicine, is a functional disorder characterized by generalized weakness of the nervous system. Individuals suffering from this condition commonly experience persistent fatigue, reduced physical and mental performance, low mood, irritability, disturbed sleep, and, in some cases, elevated blood pressure. Although various conventional treatment options are available for symptom management, no specific curative therapy has been established. Furthermore, long-term use of …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2026 Read article
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Effect of Unani Pharmacopeial Formulation Damavi on Iron Profile in Cases of Anaemia
Abstract: Anaemia is decrease in red blood cells or haemoglobin in blood; its frequency is around 2.36 billion i.e. 33% in 2015. Important symptoms associated include paleness of skin, weakness, shortness of breath, poor ability to exercise, etc. Many Unani formulations are used for treating anaemia but in this study, Tab. Damavi was used to see its effect on iron profile. This study was carried out at Regional Research Institute of …
Published in Research and Reviews : A Journal of Immunology · Vol. 12, Issue 1, 2022 · pp. 9–15 Read article
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Adjuvant Unani Formulations used in Fournier’s Gangrene Patient: A Case Study
Abstract: Fournier’s gangrene is a rare infection characterized with fast-progressing myonecrosis, which affect regions of perineum, genitalia and perianal area. E. coli, Pseudomonas aeruginosa, Streptococcus putridus, Staphylococcus and Klebsiella are commonly involved. Symptomatically presented as sudden pain in the scrotum, fever, severe toxicity, very fast spreading cellulitis of scrotal skin, extending to the groin and often to anterior abdominal wall. The aim of this case study is to acknowledge the effectiveness …
Published in Research and Reviews : Journal of Surgery · Vol. 10, Issue 2, 2021 · pp. 35–41 Read article
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Evaluation of Safety of Unani Pharmacopieal Majoon-e-Lana in Cases of Neurasthenia
Abstract: Neurasthenia, referred to as Zof-e-Asaab in the Unani system of medicine, is a functional disorder characterized by generalized weakness of the nervous system. Individuals suffering from this condition commonly experience persistent fatigue, reduced physical and mental performance, low mood, irritability, disturbed sleep, and, in some cases, elevated blood pressure. Although various conventional treatment options are available for symptom management, no specific curative therapy has been established. Furthermore, long-term use of …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2026 · pp. 37–44 Read article
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Late Onset Ataxia: A Case Report
Abstract: 57-year-old man with no prior history of any illness presented with subacute onset of gradually progressive gait ataxia, upper limb incoordination and speech issues. There was history suggestive of orthostatic hypotension and erectile dysfunction. On examination, there was normal cognition with gaze evoked nystagmus, scanning speech and limb incoordination in the form of past pointing, dysdiadochokinesia, and tandem walking abnormality suggestive of pan cerebellar involvement. The patient was evaluated with …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 1, 2024 · pp. 16–20 Read article
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Hyperlipidemia: An Herbal Remedy
Abstract: Too much cholesterol in blood is Hyperlipidemia. Cholesterol is made in liver which is essential for healthy cell membrane, brain functioning, hormone production and vitamin storage. It became problem when too much bad cholesterol or low-density lipoprotein is produced or ingested through unhealthy foods. Hyperlipidemia can be detected by routine blood test, in this excessive fat in blood accumulates over time, forming plaques on the walls of the arteries and …
Published in Trends in Drug Delivery · Vol. 5, Issue 2, 2018 · pp. 16–19 Read article
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Pharmacological evaluation of Hepatoprotective activity of Indian medicinal plants Cordia Myxa and Canscora diffusa on wistar albino rats
Abstract: Two plants (Cordia myxa and Canscora diffusa), which were claimed to possess hepatoprotective activity, were selected. The Selected plants were authenticated by an expert botanist. In the current study, herbal extraction involving solvents of decreasing polarity (petroleum ether, ethyl acetate, and hydroalcoholic) was used to extract bioactive compounds from the plants of Cordia Myxa and Canscora diffusa in polyherbal preparations. A phytochemical evaluation was performed, including an acute toxicity study …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 31–44 Read article
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Impact of Grape Seed Extract on Liver Function against Cadmium Chloride-Induced Toxicity
Abstract: The present study was designed to evaluate the antioxidant activities of grape seed and to benefit from the impact of grape seed on hepatotoxicity mediated by cadmium chloride (CdCl2). Gas liquid chromatography (GC-MS) was used to assay the chemical profile. A total of 40 male rats (10 rats per group) were divided into four groups: (1) control group, (2) grape seed group: rats treated with grape seed extract (GSE) at …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 7, Issue 3, 2020 · pp. 30–39 Read article
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TOXICOLOGY: Present-Day Difficulties for Investigating Safety Science and Target Safety Evaluation of Major Human Hepatocytes
Abstract: Preclinical toxicology has developed into a more thorough understanding of toxicity pathways from its descriptive beginnings. Technological developments have made it possible to forecast safety occurrences, mitigate adverse effects, and create safety biomarkers. Because they are able to self-renew and specialize into different types of human body cells, stem cells are currently being employed for in vitro toxicological applications. However, as compared to primary human hepatocytes, stem cell-derived HLCs perform …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 3, 2024 · pp. 31–40 Read article
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Study on safety of Unani pharmacopeial formulation Qurs Kusta Khabas- al- Hadeed and Habb- e-Marwareed in cases of Sailanur Reham (Leucorrhoea)
Abstract: Leucorrhoea is nothing but excessive vaginal discharge, it is common gynaecological complaint . Main objective of the present study was to study safety parameter of Unani formulation Qurs-e- Kusta Khubs al Hadeed and Habb-e-Marwarweed in cases of Sayalan-al-Rahim (Leucorrhoea).Study was jointly conducted in the laboratory at Regional Research Institute of Unani Medicine, New Delhi. For this 56 females patientsin the age group of 18-60 years presenting sign and symptom with …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 8, Issue 1, 2023 · pp. 1–7 Read article
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Treatment of Hepatotoxicity
Abstract: An instantaneous or prolonged response to a synthetic or natural substance is known as drug-induced liver injury, or drug-induced hepatotoxicity (DILI). There are two distinct pathways that lead to hepatotoxicity: the more unpredictable idiosyncratic mechanism and the dose-dependent intrinsic mechanism. Several pathways, some known and others speculated, may be involved in the emergence of drug-induced damage. Drug-induced liver impairment can have several causes, and elevated liver tests are one of …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 15, Issue 1, 2025 · pp. 31–37 Read article
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In Vivo Hypoglycemic Activity of Aqueous Leaf and Root Extracts of Macaranga Barteri Müll. Arg. (Euphorbiaceae) In Swiss Albino Mice
Abstract: Background: Macaranga barteri Müll. Arg. is a perennial plant in the family Euphorbiaceae and is used in African traditional medicine for the management of several ailments, including diabetes. Although the leaves and stem bark have been studied for various pharmacological activities, little is known about the therapeutic value of the roots. Objective: This study evaluated the in vivo hypoglycemic activity of aqueous leaf and root extracts of M. barteri in …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 2, 2026 · pp. 60–78 Read article
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Antidiabetic and Antioxidant Activity of Leaves of Aegiceras corniculatum (L.) Blanco (Black Mangrove): An in vitro and in vivo Study
Abstract: AbstractPurpose: Aegiceras corniculatum (L.) Blanco, commonly known as Black Mangrove, is a species of shrub or tree mangrove with a distributed Indian mangrove forest and traditionally used to treat diabetes and other health ailments. Aim: The objective of this work was to enlighten the function of Indian mangrove variety of A. corniculatum leaves on carbohydrates blemishing reactions through diabetes using in vitro and in vivo methods. Methods: The aqueous leaves …
Published in Research & Reviews : Journal of Herbal Science · Vol. 7, Issue 1, 2018 · pp. 23–31 Read article