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18 articles for “Immunology”
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Immunological and Genetic Markers of Rheumatoid Arthritis Among Women in North India: A Case-Control Study
Abstract: Background: Rheumatoid arthritis (RA) is an autoimmune disease systemically afflicting women marked by chronic inflammation around the involved joints leading to joints destruction. It has both endocrinological and immunological associations as well as genetic associations but data pertaining to women of North India is scanty. Objective: This case-control study was done to evaluate the presence and significance of major immunological and genetic markers of RA in North Indian women with …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 · pp. 1–10 Read article
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Progression in multi-omics and immunological research on host-parasite interactions: Transcriptomics, proteomics, genomics, metabolomics, and immune responses
Abstract: The interaction occuring between hosts and parasites is a quick and multi step-complex biological process that tries to influence disease outcomes. In recent years, multi-omics approaches, such as transcriptomics, proteomics, genomics, metabolomics, and immunological studies, have gathered substantial eye in dissecting these interactions at a microscopic level. These techniques enable a vast understanding of the molecular structures involved in parasitic infections and host defense mechanisms. This article reviews the advancements …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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Immunological Biomarkers and Epidemiological Evaluation of Lymphatic Filariasis Elimination Efforts in Osun State, Nigeria
Abstract: Lymphatic filariasis (LF) remains a neglected tropical disease affecting millions globally, despite extensive elimination efforts. While the interruption of transmission is a key goal, the long-term immunological effects on individuals with existing complications like elephantiasis remain poorly understood. This study assessed the current transmission status of LF and the haematological profiles of infected individuals across selected Local Government Areas (LGAs) in Osun State, Nigeria. A total of 7,388 individuals from …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 22–30 Read article
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Deciphering Th-Related Gene Interactions in Chronic Spontaneous Urticaria: Bioinformatics Insights and Drug Affinity Exploration
Abstract: Objective: There has been a great deal of interest in how inflammatory dermatosis and The cell interact, but the etiopathogenesis of chronic spontaneous urticaria (CSU) is still inadequately comprehended. Through bioinformatics techniques, the purpose of this work is to elucdate the molecular mechanism underlying Th-related genes in CSU and seeks to find the highest affinity drug. Methods: The CSU RNA expression profiling dataset provided the basis for the investigation. The …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 1–15 Read article
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Exploring the Pathophysiology of Henoch-Schönlein Purpura (HSP): A Comprehensive Review
Abstract: Blood from tiny veins can leak into nearby tissues, causing purpura, a disorder marked by red spots or patches on the skin that may have an impact on the kidneys. Henoch-Schönlein purpura (HSP) is associated with vasculitis and inflammation of blood vessels. The range of renal conditions associated with purpura includes severe glomerulonephritis and mild proteinuria. For instance, immunological complex accumulation in the renal glomeruli of HSP patients might result …
Published in International Journal of Cell Biology and Cellular Functions Read article
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Early Life Nutrition as a Determinant of Long-Term Vaccine Immunogenicity in Livestock: Mechanisms, Practical Strategies, and Species-Specific Considerations
Abstract: Early life represents a critical period for immune system development in livestock, during which nutritional exposures can exert long lasting effects on vaccine immunogenicity. Although vaccination is a cornerstone of infectious disease control in food producing animals, marked variability in vaccine induced immune responses is frequently observed under commercial conditions. Growing evidence suggests that this variability is partly driven by differences in early nutritional status, which can influence immune maturation, …
Published in International Journal of Vaccines · Vol. 3, Issue 1, 2026 · pp. 15–26 Read article
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The Impact of Dietary Components on Lactation: A Critical Review
Abstract: Infant growth and well-being depend on an adequate and species-specific amount of nutrients, antibodies, and immunological components, which are provided by human breastfeeding, the cornerstone of newborn sustenance and development However, some moms struggle with producing inadequate milk, which can put the health advantages of nursing for both mother and child in jeopardy and cause stress, anxiety, and perhaps early weaning. This review discusses the fascinating idea that food changes …
Published in International Journal of Nutritions · Vol. 1, Issue 1, 2024 · pp. 31–36 Read article
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Alopecia Areata: Complex Roots and Potential Cures
Abstract: Autoimmunity is when the healthy organs of an individual’s body are attacked by its own immune system, leading to illness or functional abnormalities. The hair follicles (HFs) are wrongly destroyed by the immune system in a condition known as Alopecia Areata and results in chronic non-cicatricial hair loss discernible by spherical patches. It’s a severely worsening or relapsing malady that can be permanent during severe falling out of hair. In …
Published in International Journal of Vaccines · Vol. 1, Issue 1, 2024 · pp. 41–54 Read article
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Development of Anti IgG Polyclonal Antibody Against Canine IgG and Their Roles in Diagnostic Purposes
Abstract: IgG plays an important part in immunological studies and also in living bodies for providing secondary immune response which triggers as passive immunization against harmful pathogens in dogs. Purpose: The aim of this investigation is to separate, identify, and refine immunoglobulin G from canine serum. Methods: Ammonium sulphate precipitation was used to separate the dog's serum, which was then concentrated over night in a dialysis bag inside of a refrigerator. …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 01–06 Read article
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Vaccination in the Era of Precision Medicine: Tailoring Immunization Strategies for Individual Risk Profiles
Abstract: The introduction of precision medicine has caused a paradigm change in the vaccine landscape. Conventionally, vaccination programmes have been homogeneous, targeting immunity at the population level without taking into consideration the individual differences in immune response and vulnerability to diseases that can be prevented by vaccination. However, a more individualised approach to immunisation has been made possible by current developments in genetics, immunology, and data analytics. Within the context of …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 32–47 Read article
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Concurrent Infection of Influenza and COVID-19: A Review
Abstract: In December 2019, a novel coronavirus that causes respiratory illnesses was identified in Wuhan, China, and swiftly spread around the world. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a virus that spreads via the respiratory system and can cause pneumonia. Members of the Orthomyxoviridae family include influenza viruses. Although there are four genera in this family, influenza is only caused by genera A and B, which are clinically important for …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 7–15 Read article
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Colostrum-Driven Epigenetic Programming in Dairy Cows: A Pathway to Optimal Reproductive Health
Abstract: Colostrum is a vital nutritional source for neonatal calves, providing immune support and essential growth factors. Recent research suggests that colostrum’s impact extends beyond immediate immunological protection, influencing long-term reproductive health through epigenetic modifications. In dairy heifers, early-life exposure to high-quality colostrum may program the developing reproductive system, affecting ovarian function, uterine health, and overall fertility. The components of colostrum, including hormones, growth factors, and bioactive peptides, can induce epigenetic …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 1, 2025 · pp. 35–51 Read article
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Nutraceuticals Unveiled: Exploring the Science, Benefits, and Future of Functional Food
Abstract: The rapidly developing subject of nutraceuticals is critically examined in this review, with a focus on its scientific basis, proven health advantages, and possible future applications in the functional food industry. Key bioactive ingredients that contribute to the therapeutics effectiveness of functional foods, including flavonoids, polyphenols, carotenoids, probiotics, and essential fatty acids, have been identified and characterized as a result of recent developments in nutritional science. Both experimental and clinical …
Published in International Journal of Nutritions · Vol. 2, Issue 2, 2025 Read article
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Gene Therapy 2.0: Harnessing Cutting-Edge Technologies for Precision Medicine
Abstract: Somatic gene therapy has become the standard form of gene therapy; this creates the Gene Therapy 2.0 era. This new and distinct time consists in the new-generation genome-editing tools and markers, more efficient systems for gene delivery, and personalized medicine approaches that raise the efficacy and safety of the treatment. Base and prime editing are two types of CRISPR-based gene editing tools have provided high precision and reduced off-target effects …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Host Invasion to Immune Evasion: Emerging Concepts in Pathogen Virulence Strategies
Abstract: Pathogens have evolved a wide repertoire of virulence strategies that allow them to invade host tissues, establish infection, and circumvent immune responses. From the initial steps of adhesion and colonization to complex molecular mimicry, antigenic variation, and immunomodulation, pathogens display remarkable adaptability. While traditional research has emphasized host cell entry and toxin production, emerging evidence highlights subtler and more dynamic strategies such as manipulation of host signaling pathways, subversion of …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 Read article
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Drug Induced Immune Mediated Nephritis: Molecular Mechanism , Pathways and Clinical Implications
Abstract: Drug-induced immune-mediated nephritis (DI-IMN) has become a more widely known cause of acute kidney injury (AKI), with the potential for development to chronic kidney disease if not detected and treated promptly. T-cell hypersensitivity to pharmaceuticals, such as antibiotics, proton pump inhibitors, nonsteroidal anti-inflammatory drugs, and immunological drugs, are the major causes for it. Beyond clinical burden, DI-IMN reflectsintricate molecular interactions that sustain interstitial inflammation and tubular injury. These interactions include …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 13–29 Read article
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Investigating mosquito innate immune defence mechanism towards malaria vaccine development
Abstract: Mosquito-borne diseases weigh heavily on public health across the globe. The mosquito’s innate immune system certainly decides whether malaria parasites survive inside the vector, and that sighted it as a logical place to discover new vaccine ideas. In this review, we examine how Anopheles mosquitoes defend themselves against Plasmodium parasites and how those defenses could be turned into tools for malaria control. We focus on three layers of immunity: antimicrobial …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 50–54 Read article
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The Role of Rubella Virus Infection among Women with Spontaneous Abortion in Al-Najaf Governorate
Abstract: Rubella virus could cause a spectrum of birth defects known as Congenital Rubella Syndrome (CRS) if the infection occurs within the first or second trimester of pregnancy. Repeated miscarriage is defined as a condition with two or more consecutive abortions before the 20–25 weeks of gestation. Rubella remains to be a severe public health problem in developing countries. Recurrent miscarriage is a multi-factorial disease, which occurs in approximately 1%–2% of …
Published in International Journal of Virus Studies · Vol. 3, Issue 2, 2026 · pp. 1–6 Read article