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59 articles for “Hydrochloric”
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Auricular Acupuncture and Oral Administration of Hydrochlorothiazide Lowers Urine Output of Nephrogenic Diabetes Insipidus Patients Compared with Hydrochlorothiazide Monotherapy
Abstract: Context: There have been no investigations on auricular acupuncture for the treatment of nephrogenic diabetes insipidus (NDI). Aim: The aim of this study is to identify the clinical efficacy of auricular acupuncture plus hydrochlorothiazide for treating nephrogenic diabetes insipidus.Patients and Methods: Thirty-one patients with NDI were randomized into two groups: the AA (auricular acupuncture) group and the control group. Patients in the AA group received a true auricular acupuncture procedure …
Published in Research and Reviews: A Journal of Medicine · Vol. 12, Issue 3, 2022 · pp. 7–10 Read article
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Optimization of Mobile Phase and Stability—Indicating HPTLC Method for the Determination of Prasugrel Hydrochloride in Pharmaceutical Dosage Form
Abstract: A simple and sensitive high-performance thin layer chromatographic method was developed and validated for Prasugrel hydrochloride. It was spotted on silica gel 60F254 TLC plates, developed using toluene:methanol (9.9:0.1, v/v) as mobile phase and scanned at 258 nm using a Camag TLC Scanner IV. The Rf value of Prasugrel hydrochloride were found to be 0.53±0.03. It was found to be linear in the concentration range of 300–1500 ng/band. The limit …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 5, Issue 2, 2018 · pp. 7–12 Read article
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Simultaneous Estimation of Irbesartan and Hydrochlorothiazide in Bulk and Tablet Dosage Form by UV-Spectrophotometry
Abstract: The present study describes a simple, accurate, precise and cost-effective UV Spectrophotometric method for the simultaneous estimation of irbesartan and hydrochlorothiazide in bulk and tablet dosage form. The solvent used was methanol and the absorption maxima for irbesartan and hydrochlorothiazide were found to be 250 nm and 270 nm respectively. A linear response was observed in the range of 4–20 µg/mL with a correlation coefficient of 0.998 for irbesartan and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 3, Issue 3, 2012 · pp. 9–17 Read article
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Acute Toxicity and Behavioural Responses of Oligochaete Worm Tubifex tubifex Exposed to Pesticide Cartap Hydrochloride
Abstract: The present study was conducted to evaluate the acute toxicity in terms of 96h LC50 and behavioural responses of oligochaete worm Tubifex tubifex upon exposure to a thiocarbamate insecticide cartap hydrochloride. All experiments were conducted in a static bioassay system using increasing concentrations of insecticide for different exposure periods. The 24, 48, 72 and 96 h LC50 values of cartap hydrochloride to Tubifex tubifex were 0.045, 0.039, 0.023 and 0.0178 …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 3, 2019 · pp. 1–5 Read article
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A Novel Analytical Method for the Simultaneous Estimation of Remogliflozin and Metformin Hydrochloride
Abstract: Specific and novel strategy has been improved for assessment of Remogliflozin and Metformin hydrochloride in mass and plan and cleaning tests by UPLC-PDA. The scientific method was the phosphate Buffer (pH: 4.5): Acetonitrile, (60:40%, v/v) utilizing the spherisorb C18, 5 µm, 4.6 mm×150 mm insightful segment with investigation season of 5 min. The progression of versatile stage through section was 1.0 ml/min. The test volume was 10 µl. The discovery …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 3, 2020 · pp. 1–15 Read article
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RP-HPLC Analytical Method Development and Validation for Quantitative Estimation of Metoclopramide Hydrochloride in Solid Oral Formulations
Abstract: RP-HPLC technique formulated for the numerical assessment of Metoclopramide Hydrochloride in tablet formulation has been confirmed for reliability. A C18 column facilitated the chromatographic separation using a mobile phase comprising 60:40 (v/v) potassium dihydrogen phosphate buffer: meth anol mixture. Such method was used to detect, where the retained time was 6.78 minutes and Metoclo pramide Hydrochloride produced a clear peaked at 273 nm. Results were in agreement with ICH Q2 …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 07–15 Read article
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Innovative Antifungal strategies: Terbinafine hydrochloride in Niosomal carriers
Abstract: Onychomycosis, an infection caused by fungi that affects fingernails or toenails, causes the nails to grow, separate from the nail bed, and become discoloured. While anybody can get, those with weakened immune systems, children and the elderly are especially susceptible. Present study was related to formulate an effective nail lacquer that would treat onychomycosis by utilizing Terbinafine hydrochloride. In this study, niosomes of a medication called terbinafine hydrochloride, an antifungal …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 · pp. 1–16 Read article
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Stability-Indicating Rp-Hplc Development and Validation for the Estimation of Lercanidipine Hydrochloride Content in Tablet Dosage Form
Abstract: A sensitive, stability-revealing, and easy reverse-phase high-performance liquid chromatographic (RP-HPLC) technique was developed and rationalized to be in a position to determine Lercanidipine hydrochloride in ingested dosing preparations. It was separated by chromatography on a C 18 column using a mobile phase containing 10 mM potassium dihydrogen phosphate buffer and methanol (20:80, v/v; pH 4.0) at a flow rate of 1.0 mL/min and UV detected at 258 nm. The retention …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 17–26 Read article
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Impact of Amiloride-Hydrochlorthiazide Diuretic Against the Pathway of Uric Acid – VLDL and Peroxynitrite in Essential Hypertension
Abstract: Thiazides induce metabolic derangement in terms of hyperlipidemia, glucose intolerance, hyperuricemia and electrolytes imbalance. Co-amiloride-hydrochlorthiazide therapy favorably corrects the hypokalemia that is induced by thiazides alone. This study was aimed to identify the interactions between serum uric acid, very-low-density-lipoprotein (VLDL) and peroxynitrite in essential hypertensive patients using amiloride-hydrochlorthiazide as antihypertensive therapy. A total number of fifty patients (12 males and 38 females) with a history of hypertension were admitted in …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 3, 2015 · pp. 6–11 Read article
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Exploring Biomedical Innovations in the Formulation and Assessment of Medicated Hard Candy Lozenges Containing Metoclopramide Hydrochloride
Abstract: The objective of this study was to formulate and evaluate metoclopramide hydrochloride medicated lozenges for antiemetic action through buccal absorption by incorporating a polymer. All formulations were developed and assessed for in-vitro drug release, physical appearance, weight variation, thickness, hardness, moisture content, mouth-dissolving time, and drug content. The prepared lozenges exhibited uniformity in weight and thickness. The hardness of all formulations ranged between 7.3–15.50 kg/cm², falling within standard limits. The …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 50–62 Read article
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Substituted Thiosemicarbazides as Corrosion Inhibitors for N80 Steel in Hydrochloric Acid
Abstract: Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 N-isonicotinoyl-N′-aryl thiosemicarbazides have been synthesized and employed as corrosion inhibitors for N-80 steel – 15% hydrochloric acid system at 25 ï‚°C. On the basis of their influence on anodic and cathodic polarization behavior, these compounds could be classified as ambiodic inhibitors. Weight loss and electrochemical data leading to their inhibition efficiencies (IEs) suggest that these inhibitors followed adsorption mechanism. Among the …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 3, Issue 2, 2012 · pp. 25–35 Read article
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Formulation and Evaluation of Diltiazem Hydrochloride Sustained Release Matrix Tablets
Abstract: Tablets are the most popular and versatile formulations with wide acceptance when compared to other dosage forms due to ease of administration, storage and transport. Diltiazem HCl is a calcium channel blocker widely used for its peripheral and vasodilator properties in the treatment of hypertension and angina. The objective of the present study is to prepare and characterize novel sustained release tablets of freely water soluble drug Diltiazem HCl using …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 2, 2015 · pp. 17–27 Read article
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Analytical Technique Optimization and ICH-Directed Verification of a Reverse Phase HPLC Approach for Quantification of Bupropion Hydrochloride
Abstract: This method was developed for retention time, peak resolution and baseline response using Bupropion Hydrochloride under optimized conditions as validation. The method resulted in two well separated, well defined peaks, a minor peak at 7.5 minutes 12 mV and a main peak at 11.52 minutes 150 mV. At the same time, the baseline has remained stable during the chromatographic run and the fluctuations of noise are very small (0.5 ± …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 47–54 Read article
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Evaluation of “Lignocaine Hydrochloride 2% Jelly” at the Peripheral Intravenous Cannulation on the Intensity of Pain amongst the Patients
Abstract: Intravenous cannulation is usually associated with some amount of pain. The application of Lignocaine hydrochloride jelly at the site prior to peripheral intravenous cannulation has been shown to decrease the intensity of pain. The objective was to study the effect of application of “Lignocaine hydrochloride 2% jelly” at the site prior to peripheral intravenous cannulation on intensity of pain. In a quasi-experimental research design 105 adult patients receiving chemotherapy and …
Published in Journal of Nursing Science & Practice · Vol. 1, Issue 1-2, 2011 · pp. 28–37 Read article
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Formulation, Development and Evaluation of Oral Thin Film of Metoclopramide Hydrochloride
Abstract: Metoclopramide Hydrochloride, an anti-emetic drug is indicated for the patients with diabetic gastroparesis and Gastro Esophageal Reflux Disease (GERD). It is difficult for a patient to swallow a tablet during emesis. So, an attempt was made to develop a patient-friendly orally dissolving film using clove oil and menthol as flavoring agents, aspartame as sweetener, polyvinyl alcohol and glycerol as film forming agent and plasticizer respectively. Based on appearance and palatability …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 2, Issue 2, 2011 · pp. 22–27 Read article
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Development and Validation of a High Performance Liquid Chromatographic Method for Related Substances of Raloxifene Hydrochloride in Bulk and Pharmaceutical Formulations
Abstract: The development and validation of reversed phase liquid chromatographic method for the determination of the related substances of Raloxifene Hydrochloride (RLH) in bulk and pharmaceutical formulation is describe. This method is simple isocratic for separation of Raloxifene Hydrochloride and related substances from each other in a thirty minutes run time. To the best of our knowledge, no method described previously in the literature has demonstrated resolution of RLH from this …
Published in Trends in Drug Delivery · Vol. 1, Issue 1, 2014 · pp. 16–23 Read article
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Formulation Development of Otic In Situ Gel containing Lomefloxacin Hydrochloride
Abstract: The present study was aimed at formulation development of a sustained release otic in situ gel of lomefloxacin hydrochloride for the treatment of chronic suppurative otitis media. Poloxamer 407 was used as the thermoreversible gelling agent. Poloxamer concentration in the range of 15–20% w/v was tried. Poloxamer 407 at 16% w/v gave satisfactory in situ gel forming formulations as it gelled near physiological temperature. Poloxamer 407 with various viscosity enhancing …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 3, Issue 1, 2016 · pp. 20–29 Read article
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Ru(III)-Catalyzed Oxidative Cleavage of Ritodrine Hydrochloride: A Kinetic and Mechanistic Study
Abstract: A systematic kinetic and mechanistic study of the oxidation of ritodrine hydrochloride (RTH) with chloramine-T (CAT) in both HClO4 and NaOH media has been carried out at 303 K. In acid medium, the reaction rate is very sluggish to be measured kinetically. Ruthenium (III) chloride ([Ru(III)]) was found to be an efficient catalyst. The reaction rate exhibits a first-order dependence on [CAT]0 in both media. It shows a fractional-order on …
Published in Journal of Catalyst & Catalysis · Vol. 1, Issue 1, 2014 · pp. 29–40 Read article
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Simple, Direct and Stability-Indicating UV Spectrophotometric Assay of Pioglitazone Hydrochloride in Pharmaceuticals
Abstract: Pioglitazone hydrochloride (PGH) is an antihyperglycemic agent used in the treatment of type-2 diabetes mellitus. A simple and straight forward UV-spectrophotometric method is presented for the determination of PGH in bulk drug and tablets by measuring the absorbance of drug solution in 0.1M H2SO4 at 269 nm. A plot of absorbance versus concentration obeyed Beer’s law over 2–36 µg ml-1 concentration range (r = 0.9981) with a molar absorptivity of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 8, Issue 3, 2017 · pp. 7–16 Read article
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A Comparative Study of Neem Oil and Mahogany Oil as Corrosion Inhibitors for Mild Steel Exposed to Hydrochloric Acid
Abstract: Corrosion is essentially an oxidation process, wherein the oxidizing agent itself undergoes reduction due to the influence of corrosion agents like salt, air, or moisture. Metals and their alloys naturally tend to react spontaneously with their surroundings, leading to a detrimental impact on their mechanical and physical properties. This project aimed to evaluate the effectiveness of two different oils, namely neem oil and mahogany oil, as agents to prevent acid …
Published in Recent Trends in Fluid Mechanics · Vol. 10, Issue 2, 2023 · pp. 13–18 Read article