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83 articles for “Formulated tablet”
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Comparative Aphrodisiac Activity of Formulated Tablet of Bombax Ceiba Linn. Extract with Sildenafil Citrate Tablet in Male Mice
Abstract: The present work deals with pharmacological studies of formulated tablet of Bombax ceiba Linn root extract comparing with marketed one. An aphrodisiac activity by mating behavior test model was investigated. The dissolved tablet slurry (400 mg/kg body wt./day) was administered orally by gavages for 28 days. Mount latency (ML), intromission latency (IL), ejaculation latency (EL), mounting frequency (MF), intromission frequency (IF), ejaculation frequency (EF) and post-ejaculatory interval (PEI) are the …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 3, 2015 · pp. 19–26 Read article
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Methods to Overcome High Moisture and Water in Herbs during Tablet Formulation
Abstract: The present study discusses about the role of PVP in converting herbal churna to tablet form. Herbal ingredients are bound to have either high level of moisture and or essential oils and hence making tablets with such herbal ingredients pose variety of challenges such as poor flow property, compressibility, hardness and capping. PVP significantly reduce most of the limitations provided the scientific method of incorporation of the same is adopted. …
Published in Trends in Drug Delivery · Vol. 6, Issue 2, 2019 · pp. 21–24 Read article
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Advancements in Analytical Techniques and Validation Methods for Pharmaceutical Tablet Formulations Using HPTLC
Abstract: High Performance Thin Layer Chromatography (HPTLC) is a versatile analytical technique which has been effectively used for pharmaceutical quality control and cost effectively, rapidly, and high throughput analyzed tablet formulations. HPTLC is different from traditional chromatographic methods as multi sample analysis is possible in one run with low consumption of solvent, which are principles of green analytical chemistry. But existing HPTLC is limited in sensitivity, resolution and reproducibility and these …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 3, 2026 Read article
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Design and Assessment of Fixed Dose Combination Containing Fenofibrate and Pravastatin Sodium in Tablet Formulation: A Bioinformatics Approach
Abstract: The aim of this is study is to formulate and evaluate fixed dose combination of Fenofibrate and Pravastatin sodium in tablet dosage for the treatment of Dyslipidemia. For the formulation and optimization of fenofibrate layer, two factor three level factorial design was used as experimental design for optimization with a minimum of nine run. All the nine trial (F1–F9) has been formulated according to the experimental design by wet granulation …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 1, 2024 · pp. 1–20 Read article
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Sumatriptan Succinate Mucoadhesive Buccal Tablets: Formulation Design, Optimization and Evaluation
Abstract: The main aim of present investigation was to develop and study mucoadhesive buccal tablets of sumatriptan succinate using different bioadhesive polymer. Nine formulations were prepared by using direct compression method with varying concentration of polymer as HPMC (Metolose SR 90SH-15000), xanthan gum (XTGM) and sodium carboxy methyl cellulose (sodium CMC). Fourier transform infrared spectroscopy was used to identify drug excipient interaction. Micromeritic properties of lubricated blend, physical properties and chemical …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 13, Issue 2, 2022 · pp. 1–20 Read article
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Formulation and Evaluation of Gastro retentive Effervescent Floating Tablets of Famotidine: Effect of Formulation Variables and In Vitro In Vivo Evaluation
Abstract: Gastro retentive effervescent floating tablets of famotidine were developed in an attempt to sustain the drug release as well as to prolong the presence of dosage form in the stomach or upper small intestine until drug is completely released in desired period of time from the formulation with special emphasis to the effect and concentration of different polymers on drug release and floatation. Tablets were prepared by direct compression method …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 2, Issue 3, 2015 · pp. 13–29 Read article
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Formulation and Evaluation of Gastroretentive Bilayered Floating Tablets of Famotidine: Effect of Formulation Variables and in vitro in vivo Evaluation
Abstract: The present investigation concerns the development of bilayered floating tablets of famotidine for prolongation of gastric residence time. An attempt was made to prepare bilayered floating tablets of famotidine by direct compression method. Two layered formulations were designed with an immediate release layer (IR) comprising of the drug, the super disintegrant Croscarmellose sodium along with the other diluents like microcrystalline cellulose and dicalcium phosphate. Three batches of immediate release layer …
Published in Trends in Drug Delivery · Vol. 2, Issue 3, 2015 · pp. 1–17 Read article
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Orally Dispersible Tablet of Mesalazine: Formulation and Evaluation
Abstract: Oral disintegrating tablets (ODTs) become increasingly more and more popular, particularly among elderly and paediatric patients who have difficulties with swallowing. The 5-aminosalicylic acid compound oral mesalazine, frequently referred to as mesalamine, is used to treat mild to severe ulcerative colitis and has a high percentage of success in causing and establishing response. Mesalazine has a topical therapeutic action at the location of the suffering colonic mucosa. The medication’s disadvantage …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 16–25 Read article
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Zolmitriptan Mouth Dissolving Tablets: Development of Formulas and Invitro Evaluation
Abstract: Pharma Burst ODT super disintegrants were used in different concentrations to manufacture Zolmitriptan fast dissolving tablets by a direct compression method. With a 28° angle of repose, there is good flow. The densities for bulk and tapped materials are 0.410 (g/ml) and 0.500 (g/ml), respectively. The compressibility index and Hausner ratio have values of 19.05 and 1.24, correspondingly. According to IP standard, weight variation test results range from 121.4 mg …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 1–15 Read article
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Formulation and Evaluation of Verapamil Solid Dispersion Tablets for Solubility Enhancement
Abstract: This study was mainly designed to solve the drawbacks of conventional verapamil solid dosage form, low bioavailability and limited clinical efficacy, by preparing solid dispersion. Verapamil solid dispersion was developed by kneading method, melt solvent method and co-precipitation method to modify the release and enhance solubility of the drug. The physical state of the dispersed verapamil in the polymer matrix was characterized by differential scanning calorimetry, powder X-ray diffraction, scanning …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 7, Issue 1, 2016 · pp. 39–54 Read article
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Formulation and In vitro Evaluation of Oral Fast Dissolving Tablets of A Novel Antidepressant Drug by Using Camphor As A Subliming Agent
Abstract: The purpose of the present investigation is to formulate fast dissolving tablets of Venlafaxine HCl, a novel antidepressant by direct compression method using camphor as subliming agent in the three different concentrations of 2%, 5% and 10%. Croscarmellose, tulsion-414 and sodium starch glycolate were used as superdisintegrants in two different concentrations of 5% and 10%. The drug-excipients compatability was ruled out through FTIR studies. A total of six formulations were …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 2, Issue 3, 2015 · pp. 12–18 Read article
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Evaluation of Effect of Rasayana Ghana Tablet (An Ayurvedic Formulation) in Management of Akala jara (Premature Ageing)
Abstract: In the present era of stress, when lifestyle disorders are on the rise, premature ageing is also one of the most prevalent disorders. Ayurvedic Rasayana (rejuvenator) drugs can provide solution for this. The present study was aimed to evaluate the efficacy of Rasayana Ghana tablet (RGT) in management of premature ageing. In this placebo-controlled randomized prospective clinical study, Rasayana Ghana tablet based upon the classical combination of Gokshura (Tribulus terestris …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 1, Issue 1-3, 2012 · pp. 77–88 Read article
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An Overview of a Study on the Formulation of Herbal Facewash Tablets
Abstract: The global industry is seeing an increase in demand for herbal formulations due to the fact that natural medicines are safer than synthetic ones. People are starting to realize that using plants can help them achieve the key goal of having attractive, healthy skin. Reetha provides antibacterial and cleaning qualities that make it appropriate for treating acne, eliminating dead skin cells, and encouraging clear skin. Clitoria ternatea has also been …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 53–66 Read article
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Formulation and Development of Iguratimod Film Coated Tablets 25 mg
Abstract: Iguratamide is chemically called as methanesulfonanilid for the treatment of rheumatoid arthritis. The present invention relates to the micron zing technology for insoluble polycrystal medicine Iguratimod, and the micronized Iguratimod has new crystallization and powder direct compression method for formulating tablets. The orally taken quick release preparation with micronized Iguratimod as active component, high efficiency super disintegrants like cross carmellose sodium, surfactants like sodium lauryl sulphate, diluents like MCC PH …
Published in Trends in Drug Delivery · Vol. 7, Issue 1, 2020 · pp. 25–31 Read article
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Comparative Study on Oro Dispersible Tablets of Candesartan Cilexetil Formulated with Natural and Synthetic Disintegrants
Abstract: Candesartan cilexetil, a BCS class II drug with low aqueous solubility and poor bioavailability (15%), poses challenges for oral delivery. To address this limitation, the present study focuses on polymer-based inclusion complexation and composite formulation strategies to enhance solubility and dissolution behavior. The drug was incorporated into β-cyclodextrin (β-CD), a cyclic oligosaccharide polymer, by the kneading method in different drug-to-carrier ratios. Among these, the 1:1 molar ratio complex exhibited the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 687–695 Read article
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Formulation Development and Evaluation of Floating Tablets of Venlafaxine Hydrochloride
Abstract: The aim of the present study was to formulate and evaluate gastroretentive floating tablets of an antidepressant drug, Venlafaxine HCl. The matrix tablets of Venlafaxine hydrochloride were prepared by employing low viscosity grade hydrophilic polymer HPMC E15LV in combination with any one of the high viscosity grades of HPMC (K4M, K15M, and K100M) as swelling polymers. Sodium bicarbonate was employed as gas generating agent. The tablets were formulated using direct …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 1, 2015 · pp. 7–15 Read article
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Formulation and Characterization of Bilayer Tablet of Anti-hyperlipidemic BCS Class II drug
Abstract: The main objective of work was to formulate co-loaded bilayer tablets of atorvastatin (ATV) and ezetimibe(EZM).ATV loaded in the immediate-release (IR) layer is an HMG CoA reductase inhibitor, while EZM, added in the immediate-release (IR) layer, is a lipid-lowering agent. The immediate release of BCS class II drugs atorvastatin and Ezetimibe, in a bilayer approach was achieved by wet granulation and fluid bed granulation followed by compression. The Preformulation studies …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 14, Issue 1, 2023 · pp. 1–18 Read article
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Formulation Development and Evaluation of Sublingual Tablets of Enalapril Maleate Using Co-processed Superdisintegrants
Abstract: Enalapril Maleate is anti-hypertensive drug and its oral bioavailability is 40%. Sublingual tablets of Enalapril Maleate were prepared to improve its bioavailability, to avoid pre-systemic metabolism and hepatic first pass elimination. Tablets were prepared by wet granulation technique using two different superdisintegrants KYRON-T-314 and INDION-414 in the different ratio (1:1, 1:2 and 2:1) by co-processing and physical mixing. FTIR (Fourier transform infrared spectroscopy) and DSC (differential scanning calorimetry) spectroscopic studies …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 5, Issue 3, 2014 · pp. 24–39 Read article
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Formulation and Characterization of Liquisolid Tablet of Skeletal Muscle Relaxants and Anti-Inflammatory Drugs
Abstract: Baclofen is a skeletal muscle relaxants and nimesulide is a Non- steroidal anti- inflammatory drug (NSAID). Baclofen is used in the treatment of muscle spasm, arthritis and spondylitis. NSAID’s are preferred to reduce the symptoms caused by muscle spasm i.e., severe pain and fever. Hence combination of drug is used to minimise the frequent use of the drug. The main objective of the present work was to enhance solubility and …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 2, Issue 2, 2015 · pp. 6–14 Read article
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Formulation Evaluation and Optimization of Orodispersible Tablets of Pantoprazole Sodium by the using of Different Superdisintigrants
Abstract: The objective of this study was to formulate and optimize an orodispersible formulation of pantoprazole sodium using a 32 factorial design for optimized the superdisintigrant concentration. Various concentration (2%,4%,6%) of superdisintegrants (SSG, CP) were added in formulation, all processing steps are carried out at temperature below 250C and relative humidity less than 35%. Procedure to manufacture orodispersible tablets by direct compression was established. The results show that the presence of …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 7, Issue 3, 2017 · pp. 11–20 Read article