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1958 articles for “Disc” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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AI-based Drug Discovery-Revolutionizing Pharmaceutical Research
Abstract: The traditional drug discovery process is often costly, time-consuming, and prone to high failure rates. The advent of Artificial Intelligence (AI) has revolutionized this field by significantly enhancing efficiency, reducing costs, and improving success rates. AI-driven approaches, including machine learning (ML), deep learning (DL), and natural language processing (NLP), have transformed key areas such as drug target identification, molecular screening, lead optimization, and clinical trial design. AI models can analyze …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 30–44 Read article
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Drug Discovery and Design: Focus on computational approaches used in the discovery and design of new drugs
Abstract: Computational approaches have revolutionized the field of drug discovery and design, offering efficient and cost-effective strategies for identifying and developing new therapeutics. This review article explores the application of computational methods in drug discovery, with a focus on virtual screening techniques, molecular docking, molecular dynamics simulations, and quantitative structure-activity relationship (QSAR) models. Virtual screening plays a crucial role in narrowing down large chemical libraries by utilizing ligand-based and structure-based approaches. …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 1, 2023 · pp. 26–30 Read article
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Reaching Conditions for Discrete-time Sliding Mode Control: Analysis and Design
Abstract: Sliding mode control (SMC) is a robust control method widely used in engineering due to its ability to handle uncertainties and disturbances effectively. In discrete-time sliding mode control (DSMC), system trajectories are constrained to sliding surfaces in the state space, leading to improved performance and stability. This paper provides an overview of DSMC, focusing on its applications, advantages, and limitations. It discusses the use of DSMC in various engineering fields …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 2, Issue 1, 2024 · pp. 7–14 Read article
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Comparative Analysis of Disc Brake Using Eco-Friendly Material
Abstract: Brakes are crucial components for slowing or stopping the vehicle. Almost all vehicles use disc brakes. The working of a disc brake is simple; when the brake pedal is pressed, braking pads are forced mechanically against the rotor or disc on both surfaces. The friction generated between the rotor and brake pads slows down the vehicle. The design and materials of disc brakes play a significant role in their performance. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 532–544 Read article
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Effect of Pad and Disc Materials on the Behaviour of Disc Brake against Fluctuating Loading Conditions
Abstract: Disc brake in an automobile plays an important role to control the vehicle during running condition. Recently, asbestos, which is widely used disc brake material is recognised as a carcinogenic material by world health organisation and has been banned throughout the world to eliminate the diseases caused by asbestos material. Therefore, people are looking towards suitable alternatives to replace asbestos with other alternative materials. In this work, an attempt is …
Published in Journal of Automobile Engineering and Applications · Vol. 4, Issue 2, 2017 · pp. 22–34 Read article
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An Approach for Discrete-Time Systems Design Using MPSM Continued Fraction Expansion Technique
Abstract: AbstractThis paper presents a new method for the design of the high-order discrete-time systems to overcome the limitations and drawbacks of some of the existing methods. It uses the Multi Point Squared-Magnitude Continued Fraction Expansion (MPSMCFE) and factorization technique for obtaining both denominator and numerator of the reduced order models. The method is extended for the design of high order systems using the reduced order model in place of original …
Published in Journal of Instrumentation Technology & Innovations · Vol. 7, Issue 3, 2017 · pp. 11–15 Read article
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Direct Torque Control Based on Discrete-Time PI Controller of an SVPWM Inverter Fed Induction Motor Using Energy Model
Abstract: A direct torque control (DTC) of an induction motor (IM) with constant switching frequency has been presented in this work which is performed using space-vector modulation (SVM). The developed DTC scheme is based on the discrete-time PI controller strategy and this has been used to achieve direct control of torque of IM. To design the discrete-time PI (DTPI) controller the energy model of induction motor is simplified at the beginning …
Published in Journal of Power Electronics and Power Systems · Vol. 2, Issue 2, 2012 · pp. 45–55 Read article
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A Review on Thermal and Structural Analysis of Disc Brakes in Motor Vehicles
Abstract: Braking is a technique that turns kinetic energy in a vehicle into mechanical energy that must be dissipated as heat. The frictional heat created at the disc-pad interface can cause high temperatures during the braking period. Thermal elastic instability (TEI), early wear, brake fluid vaporisation (BFV), and thermally stimulated vibrations can all be caused by frictional heat created on the rotor surface (TEV). In this research, a vehicle's solid type …
Published in Journal of Automobile Engineering and Applications · Vol. 9, Issue 2, 2022 · pp. 1–7 Read article
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A Review Drug and Biochemical Pharmacology Discovery
Abstract: The development of new therapeutic approaches and our understanding of disease mechanisms have both benefited ground-breaking medications as they are advanced and show the value of contemporary technologies, methodologies, and genetics in drug discovery. The synthesis, design, and application of these molecules have become a focal point in drug discovery efforts. The present research paper provided a comprehensive study of the recent developments in the field of biochemical pharmacology and …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 3, 2024 · pp. 27–31 Read article
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Intervertebral Disc Bulge in Young Individuals: Causes, Symptoms, and Remedies
Abstract: The prevalence of intervertebral disc bulge among younger individuals has raised concerns regarding its causes, symptoms, and potential remedies. This condition, typically associated with older age, has increasingly affected younger demographics. Understanding the causes behind this phenomenon is critical in addressing its impact on the younger population. The study delves into the key aspects related to intervertebral disc bulge among young individuals. The causes of intervertebral disc bulge in young …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 13–18 Read article
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Cytogenotoxicity Assessment of Asphalt Plant Discharge Water using Plant Assay
Abstract: The Allium cepa assay test was used to evaluate cytogenotoxic effects of asphalt plant discharge water at the concentrations of 10, 20, 30, 40, 50, 60, 70, 80, 90 and 100% (v/v) asphalt plant discharge water/distilled water. The distilled water served as the negative control. The analysis of the physicochemical properties and heavy metals concentrations showed that most parameters were higher than the established standards of WHO and FMENV. The …
Published in Journal of Water Pollution & Purification Research · Vol. 12, Issue 3, 2025 · pp. 100–110 Read article
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Theoretaical Analysis of Self-discharge behavior of Supercapacitor using physical parameter variation in Simulink/ MATLAB
Abstract: Understanding the self-discharge behavior of a supercapacitor is very important regarding make it more efficient for its applications. Different types of RC circuit models have been developed. We have studied the different RC circuit models and took the classical RC circuit model to study self-discharge behavior. This model requires three parameters: a capacitor (Cs), parallel resistance (R), and equivalent series resistance (Resr), and very easy to implement in simulation. The …
Published in Journal of Microelectronics and Solid State Devices · Vol. 8, Issue 1, 2021 · pp. 14–22 Read article
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Discovery Tools and Services for Libraries: Transforming Access to Knowledge in the Digital Age
Abstract: The digital transformation of libraries has led to the emergence of discovery services as pivotal tools for enhancing resource accessibility, usability, and research efficiency. This article explores the evolution, functionality, and impact of discovery services in academic and public libraries. Unlike traditional online public access catalogues (OPACs), discovery services consolidate diverse information sources—such as books, journals, databases, institutional repositories, and open-access content—into a single, user-friendly interface. By integrating advanced technologies …
Published in Journal of Advancements in Library Sciences · Vol. 12, Issue 1, 2025 · pp. 51–56 Read article
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Application of Artificial Intelligence in Drug Discovery
Abstract: The application of artificial intelligence (AI) in medicine, especially through machine learning (ML), is revolutionizing new-age drug discovery research. AI is found as an efficient and powerful tool to narrow the gap between disease detection and developing and identifying potential therapeutic agents for a cure. This review provides a summary of the latest developments in AI and its potential application in drug discovery for untreatable diseases. The review also examines …
Published in Emerging Trends in Chemical Engineering · Vol. 12, Issue 3, 2025 · pp. 22–29 Read article
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Simulation of Dual Microstructure Heat Treatment Process and Residual Stresses in Gas Turbine Disc by DeformHT Software
Abstract: Gas turbine disc is one of the most vital components in advanced gas engine. In order to improve the tensile strength and fatigue strength of the disc, finer grain size is to be attained at bore area and coarser grain structure at rim area in order to resist the growth of creep. Attempts have been made by several researchers experimentally on the development of dual microstructure for Inconel-718 by heat …
Published in Journal of Materials & Metallurgical Engineering · Vol. 7, Issue 1, 2017 · pp. 30–42 Read article
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A Study to Evaluate the Impact of a Self-instructional Module on Knowledge Enhancement Regarding the Management of Common Pregnancy Discomforts Among Primigravida Mothers in Selected Hospitals of Mysuru
Abstract: Gestation is a time of physical, emotional and hormonal changes in a woman. It is one of the important phases in a woman’s life from the time of be. It is accompanied by discomforts that are generally known as minor ailments. These common discomforts occur generally among primigravida mothers. Symptoms of discomfort due to gestation vary from woman to woman; they are nausea and vomiting, fatigue, backache, heartburn and indigestion, …
Published in International Journal of Midwifery Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 21–34 Read article
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The Dual Crisis: Antibiotic Resistance and the Discovery Void – A Review of Novel Therapeutic Strategies and Non-Traditional Approaches
Abstract: The global rise of antimicrobial resistance (AMR) has emerged as one of the most critical public health challenges of the 21st century, threatening to undermine decades of therapeutic success and rendering conventional antibiotic regimens increasingly ineffective. Parallel to the escalating resistance rates is a profound “discovery void,” characterised by a steep decline in the development of new antibiotic classes since the late 20th century. Together, these two interconnected crises create …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 47–65 Read article
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Hardware Implementation of Discrete /Inverse Discrete Cosine Transform Using Redundant Number System CORDIC Processors
Abstract: Rapid enhancement in multimedia service running on portable application has forced the development of high quality and low power implementation of complex signal processing algorithms. Image and video processing are typical application of multimedia system. Image compression and decompression using DCT/IDCT are the two algorithms commonly used in MPEG standard of image processing. For an image of N x N size, DCT/IDCT would require N4 multiplications and increases complexity. To …
Published in Journal of VLSI Design Tools and Technology · Vol. 11, Issue 1, 2021 · pp. 35–42 Read article
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Disc Spring Washer: Design and Axisymmetric analysis using ANSYS
Abstract: Disc spring washer has many applications including in wide variety of bolted connections. Disc spring washer consist of a coned disk, which has typical load deflection characteristics. It is especially useful where very large force is desired for small amount of deflection of spring. In this paper, safe design of disc spring washer is obtained using analytical procedure for given value of nominal force. Axisymmetric analysis of disc spring washer …
Published in Trends in Machine design · Vol. 4, Issue 3, 2017 · pp. 21–25 Read article
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Unani Herbal Management of Sayalan-al-Rahim (Vaginal Discharge)—A Literary Revie
Abstract: Sayalan-al-Rahim (Vaginal Discharge) is one of the most common manifestations among all gynecological disorders and is an important psychosomatic disorder affecting the psychology of women irrespective of socioeconomical status and occupation. It creates irritation in women’s freedom and decreases quality of life (QoL). The discharge may be thick or thin in consistency and whitish or yellowish in colour. Prevalence of vaginal discharge in India is about 30%. The symptoms include …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 4, Issue 3, 2017 · pp. 5–12 Read article