Search
1198 articles for “Computers”
-
Quantitative Structure-activity Relationship in Computer-aided Drug Design: A Review
Abstract: Quantitative Structure-Activity Relationship stands at the forefront of Computer-Aided Drug Design, providing a systematic framework for understanding the relationship between the chemical structure of molecules and their biological activity. The present review delves into the multifaceted realm of quantitative structure-activity relationship methodologies within the landscape of drug discovery. Through an exploration of diverse quantitative structure-activity relationship models, molecular descriptors, validation techniques, and recent advancements, the present article aims to elucidate …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 55–63 Read article
-
Analysis of Bioinformatics Software Applied in Computer-Aided Drug Design
Abstract: The integration of bioinformatic tools with computational methods has revolutionized the field of Computer-aided Drug Design (CADD), enabling researchers to expedite the discovery and optimization of new therapeutics. This review provides an in-depth analysis of the bioinformatic tools utilized in CADD, encompassing molecular docking, molecular dynamics simulation, virtual screening, homology modelling, and molecular visualization. We go over the tenets, approaches, and uses of these instruments, emphasizing their value in expediting …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 1–10 Read article
-
An Extensive Analysis of Computer-Aided Drug Design for Novel Psychotropic and Neurological Substances
Abstract: A comprehensive review of the use of computer-aided drug design (CADD) in the creation of innovative neurologic and neuropsychiatric medications is given in this article. It discusses the challenges in traditional drug discovery approaches and highlights the role of computational methods in accelerating the identification and optimization of drug candidates targeting psychiatric and neurological disorders. The method of finding new drugs has been completely transformed by Computer-Aided Drug Design (CADD), …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 19–27 Read article
-
A Study to Evaluate the Effectiveness of a Computer-assisted Teaching Program on Knowledge About the Distribution and Use of Iron and Folic Acid Tablets During the Antenatal Period Among Primigravida Mothers in Selected Villages of Holenarasipura Taluk, Karnataka
Abstract: Pregnancy is a critical period in a mother’s life, and proper knowledge about managing pregnancy is essential for maternal and fetal health. This study aimed to evaluate the effectiveness of a computer-assisted teaching program in improving knowledge about the distribution and use of iron and folic acid tablets among primigravida mothers in selected villages of Holenarasipura taluk. A one-group pre-test and post-test pre-experimental design was employed, using non-probability convenience sampling …
Published in International Journal of Midwifery Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 28–40 Read article
-
Review on Computer-Aided Drug Design in RAS Inhibitor Discovery
Abstract: This review explores the utilization of computer-aided drug design (CADD) methodologies in the discovery of inhibitors targeting the RAS pathway, a pivotal signaling cascade implicated in various cancers. Through an extensive examination of computational tools, methodologies, challenges, and recent advancements, this review aims to provide insights into the role of CADD in accelerating RAS inhibitor discovery. The discovery of effective inhibitors targeting the RAS pathway is of paramount importance in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 7–14 Read article
-
Implementation of STATIC-RANDOM-ACCESS-MEMORY-Based In-Memory Computing-architecture for improving Energy Efficiency
Abstract: The in-memory-computing architecture the improvement of big data and high-performance computing. In memory-computing (IMC) as reduces the latency and power consumption of data processing. Proposed research paper static random-access memory-based IMC architecture. By completing internal write-back, NMOS transistors increase computational efficiency and eliminate the need to read the computational output right away. A 128×128 STATIC-RANDOM-ACCESS-MEMORY-IMC macro chip is designed using the 78-nm technology. The energy efficiency of 55.3TOPS/W with supply …
Published in Journal of VLSI Design Tools and Technology · Vol. 15, Issue 1, 2025 · pp. 25–35 Read article
-
Effects of Cluster Computing on Big Data Analysis and Network Topology
Abstract: The rapid expansion of big data has posed substantial difficulties for conventional computing systems. As a result, cluster computing has grown to be a potent method for effective large data processing. Cluster computing involves multiple interconnected nodes functioning as a unified system, pooling together their processing, storage, and memory resources. These nodes are typically connected through high-speed networks such as ethernet or InfiniBand, facilitating efficient data sharing and communication among …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 1, Issue 1, 2023 · pp. 31–39 Read article
-
Computers: Evolution, Breakthroughs, and Future Innovations
Abstract: The computer, a cornerstone of modern technology, has evolved through significant inventions and innovations that have transformed societies and industries worldwide. From the early mechanical calculating machines, such as Charles Babbage’s Analytical Engine, to the advent of electronic computers like the ENIAC, the journey of computing is marked by breakthroughs that have enabled rapid advancements in data processing, communication, and automation. The introduction of integrated circuits, microprocessors, and the development …
Published in Trends in Opto-electro & Optical Communication · Vol. 15, Issue 2, 2025 · pp. 11–23 Read article
-
Future-proofing the Mind: Fostering Robust Innovation in Soft Computing and Computational Intelligence
Abstract: This study examines the impact of Computer Science (CS) and Soft Computing (SC) on a few scholarly disciplines and way of life. The study considers points to improve calculation execution by utilizing computational intelligence (CI) techniques, progressing the steadiness of statistical classification (SC) models, and optimizing them through algorithmic upgrades. These adjustments encourage the method of altering, selecting, and creating oneself, indeed in challenging circumstances. The effect on work, protection, …
Published in Journal of Mobile Computing, Communications & Mobile Networks · Vol. 11, Issue 1, 2024 · pp. 1–6 Read article
-
Modern Computer-aided Drug Design Methods: A Review
Abstract: Computer-aided drug design (CADD) has emerged as a crucial tool in the drug discovery process, offering a time-efficient and cost-effective approach to identifying potential drug candidates. This review aims to provide an overview of modern CADD methods, including high-throughput screening (HTS), structure-based drug design (SBDD), ligand-based drug design (LBDD), structure-based virtual screening (SBVS), and ligand-based virtual screening (LBVS). We discuss the basic principles, applicability, and limitations of each method, highlighting …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 2, 2024 · pp. 14–20 Read article
-
Use of the Computer Statistics in Oncology
Abstract: Currently, the use of computer statistics and computer statistical modeling in oncology for obtaining an accurate diagnosis, determination of the choice of treatment method and its correction in the process of ongoing treatment, prediction of the outcome of the disease, and evaluation of the effectiveness of the chosen treatment tactics is a decisive factor. The use of computer statistics, based on an adapted scientific and statistical package of the SSP …
Published in Research & Reviews : Journal of Statistics Read article
-
The Significance and Applications of Parallel Computing in the Modern Era
Abstract: This article explores the advancements in parallel computing, focusing on its applications in various domains such as scientific simulations, big data analytics, artificial intelligence, and real-time processing. We discuss the architectural shifts from traditional single-core processors to multi-core and many-core systems, along with the role of graphics processing unit (GPU)-based computing and specialized hardware like tensor processing units (TPUs) and field programmable gate arrays (FPGAs). Furthermore, the article examines contemporary …
Published in Recent Trends in Parallel Computing · Vol. 12, Issue 1, 2025 · pp. 24–38 Read article
-
Study on Cloud Computing’s Deployment Models
Abstract: Cloud computing represents a significant technological advancement in the information technology industry. It is one of the fastest-growing technologies, where computing resources are managed and allocated across the globe via the internet. Today, cloud computing is a key topic in many computer science curricula due to its extensive impact on various computing domains, particularly big data, which would be impossible without cloud computing. Cloud computing is an internet-based technology that …
Published in Current Trends in Information Technology · Vol. 14, Issue 3, 2024 · pp. 26–33 Read article
-
Offloading Computation to the Cloud
Abstract: Mobile devices are increasingly relied upon for complex and resource-intensive applications such as real-time video processing, augmented reality, and machine learning. However, their limited computational power, storage capacity, and battery life pose significant challenges. Computation offloading to the cloud has emerged as a promising solution to overcome these limitations by transferring demanding tasks from mobile devices to remote cloud servers. This approach enables improved performance, reduced energy consumption, and enhanced …
Published in International Journal of Mobile Computing Technology · Vol. 3, Issue 2, 2025 · pp. 27–37 Read article
-
A Critical Review of Generative Design Methods in Computer-Aided Drafting
Abstract: In the realm of Computer-Aided Drafting (CAD), generative design methods have become a potential strategy for automating and enhancing the design process. These methods generate a wide range of design possibilities based on given characteristics and limitations by using algorithms and computational tools. The objective of this critical study is to assess the benefits, drawbacks, and implications of generative design techniques in CAD. A notable result of this merger is …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 1, Issue 1, 2023 · pp. 1–6 Read article
-
Self-Driving Cars and Computer Vision: Enhancing Computer Vision for Autonomous Vehicle Navigation
Abstract: Autonomous vehicles, commonly known as self-driving cars, are transforming the transportation sector by aiming to enhance road safety, ease traffic congestion, and boost overall efficiency. Central to the operation of these vehicles is computer vision, which enables them to perceive and understand their environment. This paper examines how computer vision contributes to the navigation of autonomous vehicles and highlights its continuous developments. Specifically, it examines key challenges such as real-time …
Published in Research & Reviews: A Journal of Embedded System & Applications · Vol. 13, Issue 2, 2025 · pp. 1–10 Read article
-
Quantum Computing: A Review
Abstract: The field of quantum computing is rapidly evolving and holds the potential to fundamentally change our approach of tackling complex problems. In this research, the fundamentals of quantum computing and some possible uses for it are examined. Also, a general review of classical computing and its shortcomings in several specific problem-solving scenarios is outlined. Qubits serve as the foundational elements of quantum computing. The different kinds of quantum bits, or …
Published in Journal of Software Engineering Tools & Technology Trends · Vol. 11, Issue 1, 2024 · pp. 30–42 Read article
-
Implementing and Analyzing Network Commands in Cloud and Edge Computing Environments with Cisco Simulators
Abstract: The present review examines edge and cloud topologies and compares them according to latency. Instead of using distant data centers like cloud computing platforms, edge computing designs process data physically close to the source. Increased demand for Internet of Things (IoT) devices, which are growing more concerned with real-time data processing and analysis, has fueled the expansion of edge computing and cloud computing. In essence, each of these designs offers …
Published in International Journal of Satellite Remote Sensing · Vol. 2, Issue 2, 2024 · pp. 62–69 Read article
-
Hierarchical Computational Modeling of Physical Structure Across Quark, Nuclear, and Atomic Scales
Abstract: We present a modular, multi-scale computational framework that integrates physical modeling and visualization across quark, nuclear, and atomic scales within a unified pipeline. Developed to address the traditional fragmentation between sub-nucleonic, nuclear, and electronic representations, the system provides a continuous data flow and visualization bridge spanning from femtometers to ångströms. The framework consists of three primary modules: a particle-level module illustrating nucleons as confined quark-triplets with effective flux-tube geometries; a …
Published in Research & Reviews : Journal of Physics · Vol. 15, Issue 1, 2026 Read article
-
Harnessing the Growth Potential of Cloud Computing in Agriculture
Abstract: Unlocking the Green Revolution: A Comprehensive Exploration of Cloud Computing Integration in India's Agricultural Landscape. The integration of cloud computing technology in the agricultural sectors of India is poised to play a pivotal role in propelling the nation's holistic development. This paper delves into the dynamic realm of cloud computing, serving as a catalyst for innovation and efficiency in agriculture. By eliminating the need for maintaining expensive computing infrastructure, cloud …
Published in International Journal of Cheminformatics · Vol. 1, Issue 1, 2023 · pp. 32–37 Read article