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37 articles for “Catalase”
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Biochemical Biomarkers as a Tool in Chromium Induced Toxicity to Green Tiger Prawn, Penaeus semisulcatus (De-Haan, 1844)
Abstract: Estuarine ecosystem and its biodiversity are at higher risk due to coastal contamination by heavy metals and conservation of biodiversity can be accomplished by utilizing biomarkers of pollutant at different exposure levels. In the present study, chronic toxicity test was conducted to evaluate the antioxidants and enzymes as the possible biomarkers in Green Tiger Prawn, Penaeus semisulcatus. The chronic endpoint value (MATC), no-observed effect concentration (NOEC), and low-observed effective concentration …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 4, Issue 2, 2014 · pp. 1–12 Read article
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Anti-Ulcer Activity of Ethanolic Extract of Sesamum indicum Seed on Indomethacin-Induced Ulcer Model and Its Antioxidant Property in Gastro-Protection
Abstract: The present study was intended to investigate and evaluate the antiulcer activity of the ethanol seed extract of Sesamum indicum Linn. using Indomethacin Induced Ulcer in Albino rats and to determine its link between oxidant or antioxidant parameter. The extract of Seamum indicum Linn. was tested on indomethacin induced gastric ulcer in Albino rats. The antiulcer activity of high dose (400 mg/kg) and low dose (200 mg/kg) of ethanolic extract …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 2, 2015 · pp. 18–25 Read article
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Antioxidant activity of Passiflora foetida leaf extracts and silver nanoparticles in diabetic induced rats
Abstract: The anti-oxidant system present in our body prevents against the free radicals. Anti-oxidants were glutathione peroxidise,serum catalase,vitamin E, ascorbic acid and superoxide. In our study the plant extract of Passiflora foetidae were used to estimate the antioxidant levels in diet-induced diabetic rats. The mean of glutathione peroxide of normal rats was 92.98±1.65. "The mean of diet-induced diabetic rats was 152.50 ± 1.92*. Diabetic rats treated with sitagliptin and vildagliptin had …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 10–16 Read article
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Effects of Intraperitoneal Administration of ATRA on the Testis of Elastase Induced Emphysematous Rats
Abstract: Emphysema is the pathological manifestation primarily associated with lungs. However, there are evidences of extra-pulmonary manifestations related to emphysema. The inflammation developed during emphysema triggers the release of several inflammatory mediators, which affects the proximal as well as distal organs. The present study was designed to determine the effect of inflammatory spillage on testicular tissue of male Sprague dawley rats; moreover, the main focus was to assess the potential role …
Published in Research and Reviews: A Journal of Toxicology · Vol. 6, Issue 3, 2016 · pp. 1–12 Read article
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Anti-Ulcer Activity of Methanolic Extract of Mucuna Pruriens Seed on Indomethacin Induced Ulcers in Albino Rats
Abstract: The present study was intended to investigate and evaluate the antiulcer activity of the methanol seed extract of Mucuna pruriens using indomethacin induced ulcer in albino rats and to determine its link between oxidant or antioxidant parameter. The extract of Mucuna pruriens was tested on indomethacin induced gastric ulcer in albino rats. The antiulcer activity of high dose (400 mg/kg) and low dose (200 mg/kg) of ethanolic extract of Mucuna …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 5, Issue 2, 2015 · pp. 1–8 Read article
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Antibacterial Action of Bacillus coagulans Against Diverse Pathogens and its Relevance as Probiotics
Abstract: Probiotics are living organisms that give benefits to the host organism by improving the intestinal microbial balance. Probiotics have various beneficial effects as it maintains a healthy gut, healthy vaginal flora and boost the immune system. There are different strains of lactic acid bacteria that are used as probiotics but Bacillus coagulans is a good bacterium that is used in the form of probiotic supplements. In the present study, B. …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 13, Issue 2, 2023 · pp. 21–25 Read article
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Pyrethroid Mediated Some Macromolecular and Biochemical Changes in Freshwater Teleost
Abstract: Abstract In present investigation, a freshwater fish Channa punctatus was exposed for 21 days to synthetic pyrethroid malathion at sublethal concentrations of 0.007mg L−1 and 0.093 mg L−1 that represented 10% of the 96 h LC50 of the pesticide for this fish. Tissue samples were collected at the end of the experiment and analyzed to determine oxidant/antioxidants status (catalase, LDH, DNA content, protein content, cortisol, etc.) of the fish. Enzyme …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 2, 2020 · pp. 14–21 Read article
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Foliar Application of Zinc Nanoparticles Improves Photosynthetic Performance in Wheat Plants
Abstract: The present study investigated the impact of foliar spray of zinc oxide nanoparticles on physiological and biochemical reactions in wheat (Triticum aestivum L.) Foliar spray with zinc oxide nanoparticles at 10 mg/l positively increased pigment content and biomass in comparison to control while a significant reduction in chlorophyll content and biomass accumulation was observed at higher concentration of 1000 mg/l. A study of Chlorophyll a fluorescence parameters at 10 mg/l …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 11, Issue 2, 2021 · pp. 12–23 Read article
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A research study into the interactions between the monoherbal formulations of arjuna and Aloe vera in a rat model of isoproterenol-induced cardiotoxicity
Abstract: Aloe vera is a herbal dietary supplement, and arjuna is used for its cardioprotective properties. Rats were given isoproterenol hydrochloride subcutaneously to cause myocardial infarction. The purpose of the study was to identify any potential pharmacodynamic interactions between the commercially available formulations of Aloe vera and arjuna. Materials and Procedures: The electrocardiogram (heart rate, ST segment elevation time, QRS complex amplitude), serum cardiac markers (creatine kinase, isoform of creatine kinase, …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 2, 2025 · pp. 1–10 Read article
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Study Review: Molecular Mechanisms of Nanoparticle-Cell Interaction – Implications for Drug Delivery and Toxicity
Abstract: The application of nanoparticles in drug delivery and biomedical therapies holds great promise, yet their interaction with cells and the underlying molecular mechanisms remains areas of active research. This study explores the molecular mechanisms of nanoparticle-cell interactions, focusing on the effects of gold nanoparticles (AuNPs) and silica nanoparticles (SiNPs) in human cancer cell lines (HeLa and MCF-7). The study examines how nanoparticles are internalized by cells, their impact on cellular …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 · pp. 31–40 Read article
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Review on Dioscorea alata and its Pharmacological application
Abstract: Dioscorea alata, also known as water yam, is an important crop found worldwide. About 600 different species have been reported worldwide. Many nations, including South America, Africa, Australia, and the southern United States, cultivate D. alata. D. Alata is a member of the Discordance family and has been demonstrated to possess anti-inflammatory, anti-apoptotic, and antioxidant qualities. Dioscorea's metabolites include phenolic chemicals, which reduce sugars, flavonoids, glycosides, saponins, alkaloids, anthraquinones, proteins, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 80–86 Read article
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Review on Histological and Functional Effect of Alcohol on Liver and Kidney
Abstract: Alcohol consumption represents the third largest risk factor for disease burden in most countries of the world. The purpose of this review is to give a comprehensive report of the existing data on the potential adverse effects of alcohol on liver and kidney toxicity. We used 82 different published materials for the compilation of this review article. The Google search engine was used for accessing published materials from databases like …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 7, Issue 2, 2018 · pp. 49–62 Read article
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Effects of Chlorpyrifos as Inducer for Oxidative Stress in Liver, Kidney and Spleen of Freshwater Fish, Pseudetroplus maculatus (Bloch, 1795)
Abstract: Chlorpyrifos is one of the most common organophosphate insecticides found abundantly in freshwater ecosystems and has been detected in agricultural and fishery products worldwide. The study focused to determine the effect of chlorpyrifos on the induction of oxidative stress in freshwater fish Pseudetroplus maculatus. Fish were exposed to sublethal concentrations (0.661 and 1.32 μg/l) of chlorpyrifos for 15 and 30 days. Activities of antioxidant enzymes and the levels of hydrogen …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 1, 2018 · pp. 20–29 Read article
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Hepatoprotective Efficiency of Nigella sativa L. Extract on D-Galactosamine Induced Toxicity
Abstract: The Protective role of Nigella Sativa L. alcoholic extract (NSE) was investigated on D-Galactosamine (DGalN) induced hepatotoxicity in rats. Twenty four adult wistar albino rats were divided into four groups viz Control, D-Galatosamine induced hepatotoxicity, Nigella sativa alcoholic extract and Nigella Sativa alcoholic extract pretreatment prior to the administration of D-Galactosamine. After treatment, the rats were sacrificed, blood and liver samples were collected for determination of Serum Aspartate transaminase (AST), …
Published in Research and Reviews: A Journal of Toxicology · Vol. 1, Issue 1-3, 2011 · pp. 39–44 Read article
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Arsenic Induced Oxidative Stress and Its Possible Reversal by Chelation Therapy
Abstract: Arsenic (As) is a metalloid listed in group Va of the periodic chart. It exists in nature in the oxidation states +V (arsenate), +III (arsenite), 0 (arsenic) and −III (arsine). In the aqueous environment inorganic arsenic appears commonly in the oxidation states +V and +III as arsenous acid (As (III)), arsenic acid (As (V)), and their salts. Chronic and acute exposures of arsenic leads to cancer, cardiovascular disease (hypertension and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 2, 2012 · pp. 16–37 Read article
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Mercury-induced Biochemical Changes in Perna viridis Exposed in Chronic Toxicity Test
Abstract: In the present study, the Asian green mussel, Perna viridis, was exposed to 50, 75, 113, 160 and 253 µg/L Hg concentrations under chronic toxicity for the assessment of biochemical biomarkers. Higher levels of glutathione S-transferase (GST), reduced glutathione (GSH), lipid peroxidation (LPO) and lower levels of protein, catalase (CAT) and acetylcholinesterase (AchE) were found. The values were found to be significant at P < 0.01. This study suggests that …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 1, 2012 · pp. 15–22 Read article
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Effect of Ethylene Glycol Monomethyl Ether on Testicular Antioxidant System in Adult Rats
Abstract: Ethylene glycol monomethyl ether (EGME), an environmental contaminant, which is widely used as a solvent especially in lacquers, paints, dyes, pesticides, liquid soap, cleaning solution & cosmetic, chemical intermediates, as a diluent for hydraulic brake fluid etc on industrial scale, has been shown to induce reproductive abnormalities in male rats. The precise nature and mechanism of action of EGME on the male reproductive system is not clear. In the present …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 2, 2013 · pp. 1–6 Read article
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Attenuation of Doxorubicin-induced Hepato- and Nephrotoxicity by Proanthocyanidins from Myrica nagi Bark in Wistar Rats
Abstract: Due to dose-related toxic effects, doxorubicin, a very potent and often used anti-cancer medication, is largely limited. The current research investigated the protective impact of Myrica nagi bark (PMN)-isolated proanthocyanidins on hepato-induced doxorubicin and nephrotoxicity in Wistar rats. The animals were subdivided into six classes of five rats each. Group I got PMN (200 mg/kg, p.o.) for 21 days, Group II received Doxorubicin (DXR) (60 mg/kg, i.p.) once, 48 h …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 3, 2020 · pp. 19–28 Read article
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Biochemical Assessment of Fish Channa punctatus Exposed to Heavy Metal Loaded Waste Water with Serum Biochemistry and Oxidative Stress as Biomarker Responses
Abstract: Due to Rapid industrialization from past two decades, there has been increase in industrial wastes which has been discharged into the nearby water bodies, leading to the damage of the whole ecosystems and marine habitat. These industries possess a potential threat to the aquatic ecosystem besides, its flora and fauna. One such condition has been witnessed in the present study in MIDC Area of Amravati region of Maharashtra India. In …
Published in Research and Reviews: A Journal of Toxicology · Vol. 12, Issue 3, 2022 · pp. 33–42 Read article
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Pharmacokinetic Study of Iron Absorption from Unani Compound Formulation in Animals
Abstract: Background: Iron is an indispensable element for survival and normal functioning of the human cells. It is required for a large number of biochemical reactions in the cells. It is a vital component of haemoglobin, myoglobin, cytochromes, catalases and many other enzyme systems like Krebs cycle. It is essential for oxygen transport and oxidation reactions in cells. Iron deficiency is the most prevalent deficiency disorders of human beings in the …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 10, Issue 1, 2023 · pp. 1–5 Read article