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28 articles for “Cardiac therapeutics”
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Application of Bio-Nano Composite Photoelectric Material for the Therapeutic of Cardiac Disorder: An Integration of Bio-hybrid System
Abstract: For the treatment of fibrillation i.e. a cardiac disorder, wherein electrical currents are used as therapy. This disorder manifests chaotic and accelerated heart rhythm, preventing the pumping of blood to the rest the organism. In considering the remedy of this heart disease, in this study we devised therapeutics for the same through bio-nanocomposite photoelectric patches; by the application of direct immobilization of bacterial photosynthetic reaction center (RC) proteins on nanocrystalline …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 3, Issue 2, 2013 · pp. 1–7 Read article
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Standardization and Quantitative Estimation of Chemical Constituents of Lipotab Unani Herbal Tablets
Abstract: The Unani poly-herbal drug Lipotab tablet is therapeutically used for cardiac health. There are no standard procedures available for evaluation of the constituents present in any herbal products. Standardization and quality control of indigenous medicines will not only increase the benefit of the drugs but also translate into higher profits for the industry. In the present study, the constituents of Lipotab tablet, i.e., turmeric (Curcumin) and garlic (thiosulphinate allicin) has …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 1, Issue 2, 2014 · pp. 23–31 Read article
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Cardiotoxicity Associated with Tyrosine Kinase Inhibitors in Philadelphia Chromosome-Positive Leukemias: An Overview of Mechanisms, Clinical Implications, and Management Strategies
Abstract: Tyrosine kinase inhibitors have greatly enhanced the outlook for individuals diagnosed with Philadelphia chromosome-positive leukemias, including chronic myeloid leukemia and acute lymphoblastic leukemia. However, these therapeutic agents are associated with Cardiotoxicities and can manifest as left ventricular dysfunction, which may progress to heart failure, along with electrocardiographic abnormalities, dysrhythmias, hypertension, myocardial ischemia, and thromboembolic events. The unclear frequency of drug-induced cardiovascular complications, coupled with uncertainties regarding their reversibility and long-term …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 18–24 Read article
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Pharmaceutical Standardization of Rakta Akika Bhasma and Pishti
Abstract: Background: Akika Pishti is widely used in therapeutics to treat various disease conditions like Hridaroga (Cardiac disease) Manoroga (psychic disorders) and Raktaja Vikara (bleeding disorders). Some references found in classics also emphasized the use of Akika Bhasma. However, no work has been done to date to standardise Rakta Akika Bhasma and Pishti's pharmaceuticals. Aim: The present research work is aimed to establish the pharmaceutical standardization of Rakta Akika Bhasma and …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 9, Issue 2, 2022 · pp. 20–29 Read article
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Differential Gene Expression Analysis of Human Atrial Fibroblasts Reveals Dysregulation of RNA Metabolism and Translational Machinery in Atrial Fibrillation
Abstract: Atrial fibrillation (AF) is a complex cardiac arrhythmia characterized by extensive structural remodeling and the activation of atrial fibroblasts, which drive the progression of fibrosis. To identify the underlying transcriptomic alterations, we analyzed six human atrial fibroblast RNA-Seq datasets (three control and three AF) retrieved from the Sequence Read Archive. After performing rigorous quality control and adapter trimming, we aligned the reads to the GRCh38 human reference genome using a …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 2, 2026 · pp. 15–25 Read article
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Genomic Medicine Revolutionizes Heart Care: A New Standard of Practice
Abstract: The integration of genomic and precision medicine into cardiovascular healthcare represents a transformative advancement in addressing the global burden of cardiovascular diseases (CVDs). Precision medicine leverages genomic, proteomic, and metabolomic data to provide personalized care, optimizing treatment outcomes while minimizing adverse effects. Over the past decade, extensive research has highlighted its potential to revolutionize the management of major CVDs, including myocardial infarction, hypertension, and heart failure, which significantly contribute to …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 30–37 Read article
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Impact of Hypoxia on Cardiopulmonary Adaptation in Canines: A Comprehensive Review
Abstract: Hypoxia triggers a series of cardiopulmonary responses that play an important role in oxygen delivery and the continuation of physiological activity in mammals. Canines are also a useful translational model of study to examine these adaptive responses because of their anatomical, physiological, and cardiopulmonary differences with humans. This review summarizes the experimental data of acute, subacute and chronic hypoxia in dogs with particular focus on the variations in cardiac functioning, …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 1, 2026 · pp. 13–24 Read article
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Renin-Angiotensin System as a Therapeutic Target for Colorectal Cancer Liver Metastasis
Abstract: Classically, renin-angiotensin system (RAS), for a long time, has been perceived as the main regulator of cardiovascular homeostasis, due to its effect on blood vessels contraction or cardiac hypertrophy and is known to maintain blood pressure and body fluids. Hence, its pharmacological regulation is mainly associated with the management of hypertension. Currently, it was found that the RAS is involved in a broad range of physiological processes and diseases. RAS …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 2, 2018 · pp. 1–14 Read article
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A Comprehensive Review of Analytical Method – Development and Method Validation of Digoxin Tablets
Abstract: The main objective of this review is to give an outline of the method development and validation process of digoxin, and this review covers the different types of spectroscopic and chromatographic techniques, such as HPLC, UHPLC-Tandem mass spectroscopy, TLC, and LC-MS. A novel method for the determination of digoxin in biological samples has been developed and validated, focusing on improving sensitivity, specificity, and reproducibility. The method was validated in terms …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 47–58 Read article
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Phytochemical and In vitro Regeneration Study of Vitex Nirgundo and Piper Betel
Abstract: Medicinal plants have been a major source of therapeutic agents since ancient times to cure human disease. Interest in the revival of natural drugs started in last decade mainly because of the wide spread belief that green medicine is healthier than synthetic products. Despite the major advances in the modern medicine, the development of new drugs from natural products is still considered important. In recent times, interest in plant research …
Published in Research & Reviews : Journal of Herbal Science · Vol. 8, Issue 1, 2019 · pp. 32–38 Read article
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Investigating the Therapeutic Potential of Badranjboya in Unani Systemic Medicine
Abstract: Badranjboya, a potent medicinal plant derived from Nepeta hindostana, stands as a flowering plant or perennial herb belonging to the illustrious Lamiaceae family, known to thrive in the bountiful lands of India and Pakistan. Its profound importance within Unani literature is evident, for it has been hailed as “Mufarreh_al_Quloob,” denoting its esteemed status as a heart tonic. This venerable recognition can be traced back to the enlightening works of the …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 10, Issue 2, 2023 · pp. 11–15 Read article
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Menstrual Blood Banking: A Future Need and Scope
Abstract: Stem cells abundant in menstrual blood possess the capacity to develop and differentiate into various cell types. The regenerative capacity of these stem cells derived from menstrual blood is comparable to that observed in stem cells present in umbilical cord blood and bone marrow. Every healthy woman experiences menstruation on average once every 28 to 30 days from the time of menstruation till menopausal. Menstrual blood banking involves storing menstrual …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 2, 2024 · pp. 35–39 Read article
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The Therapeutic vade mecum of Green Tea
Abstract: Green tea has achieved a remarkably impressive healing, or curative reputation in the West —more so, in recent times. The herb is replete with a historical legacy as a safe, effective anti-inflammatory, analgesic, and antioxidant agent. Research has shown that green tea has the ability to reduce arthritic pain, including the risk of certain forms of cancer. Other studies suggest that green tea has the ability to stabilise blood lipids—this …
Published in Trends in Drug Delivery · Vol. 5, Issue 3, 2018 · pp. 22–30 Read article
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Preliminary Evaluation for Phytochemicals in Tribulus Terrestris and Its Antibacterial Activity
Abstract: Medicinal herbs have a long history in improving human health and curing various diseases. A wide interest has been made for researchers using herbal material in identification of the active components and verification of their efficiency. We evaluated the aqueous and methanol extracts of Tribulus terrestris (T. terrestris) for the phytochemical content and its antimicrobial activity. Phytochemical screening of the extracts revealed the presence of alkaloids flavonoids, saponins, anthraquinone, terpenoids, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 4, Issue 3, 2014 · pp. 1–6 Read article
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Therepi: A Replenishable Implanted Epicardial Reservoir
Abstract: The healthcare technology has been advancing at such a high pace which was not expected some years back. This paper is an attempt to introduce not so known, still existing and in-development phase, techniques which can revolutionize the healthcare industry in different domains. The recent technological development in coronary therapies have shown a great promise in restoring the abnormalities present in the heart after the patient experiences heart attack; certain …
Published in Research and Reviews: A Journal of Health Professions · Vol. 9, Issue 2, 2019 · pp. 12–16 Read article
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A Case Report of Diabetic Microalbuminuria Managed with Shatavari Gokshru Rasayana
Abstract: Diabetes mellitus reduces life expectancy of patient up to 10 years. Diabetes mellitus has risk of fatal target organ damage leading to complication like diabetic renal disease, retinopathy, cardiac disease, neuropathy, etc. that is believed to be occurring due to vascular changes or endothelial dysfunction. Longevity of the diabetic patients may be increased if these changes are arrested. This change leads to microalbuminuria and therapeutic measures if used well in …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 8, Issue 1, 2023 · pp. 14–17 Read article
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Exploring the Bioactive Potential of Himalayan Lichens: Phytochemical and Antimicrobial Profiling of Xanthoparmelia tinctina and Pyxine subcinerea Extracts
Abstract: The symbiotic association that develops between cyanobacteria, algae, and fungi results in the composite organism known as lichens, which has traits similar to those of plants but differs in its separate parent organisms. Lichens can have a variety of morphological characteristics, including foliose structures that resemble flat leaves, crustose structures that resemble flake crystals, fruticose branches that have short, leafless branches, and leprose-powder-like appearances. Due to their therapeutic potential, lichens …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 2, 2024 · pp. 21–28 Read article
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Comprehensive Review of Moebius Syndrome: Clinical Landscape, Etiology, and Therapeutic Challenges
Abstract: Moebius syndrome, a rare congenital neuromuscular disorder, presents with non-progressive facial weakness, limited eye abduction, and diverse manifestations affecting cranial nerves. This comprehensive review explores its clinical landscape, emphasizing the need for extensive investigations into its elusive etiology and genetic underpinnings. The estimated prevalence is 1 in 250,000 live births, with sporadic cases prevailing. Initial symptoms, evident from birth, encompass difficulties in sucking, and feeding, and absent facial expressiveness. Beyond …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 27–38 Read article
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Role of Clinical Pharmacists During Cardiopulmonary Resuscitation in Intensive Care Units and Emergency Departments: A Narrative Review
Abstract: Cardiopulmonary resuscitation (CPR) represents an essential emergency procedure designed to reestablish spontaneous circulation and enhance survival rates among individuals suffering cardiac arrest. Successful resuscitation necessitates prompt clinical judgment, expeditious pharmaceutical interventions, compliance with advanced cardiovascular life support (ACLS) guidelines, and synchronized interprofessional collaboration. During recent decades, clinical pharmacists have gained greater incorporation within emergency response and resuscitation units owing to their specialized knowledge in medication oversight, pharmacotherapeutic enhancement, and patient …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 4, Issue 1, 2026 · pp. 12–25 Read article
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Grape Seed Extract: Potent Chemoprotective Agent: Phytochemical Analysis and GC-MS Study
Abstract: Plant extracts or secondary metabolites have served as antioxidants in phytotherapeutic medicines to protect against various diseases for centuries. Phytochemicals are naturally occurring in the medicinal plants, leaves, vegetables and roots that have defence mechanism and protect from various diseases. Phytochemicals are primary and secondary compounds. Chlorophyll, proteins and common sugars are included in primary constituents and secondary compounds include terpenoids, alkaloids, quinines, flavonoids, sterols, saponins, tannins and phenolic compounds. …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 5, Issue 3, 2016 · pp. 30–39 Read article