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46 articles for “Antifungal Infection”
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Synthesis, Antibacterial Evaluation and Antifungal Study of New Biochemical Derivatives
Abstract: Bacterial and fungal infections have become widespread recently due to the spread of epidemics, diseases, and bacterial infections. As a result, infection rates have increased, prompting many researchers to develop new antibiotics to reduce the spread of these prevalent diseases. Researchers have prepared biochemical compounds similar in structure to drugs that eliminate infections and reduce their spread. One such derivative is imidazole; a well-known compound used in many medications for …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 1, 2026 · pp. 19–28 Read article
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Ocular Films as a Drug Delivery System Against Fungal Infections: Current Insights and Future Directions
Abstract: Fungal infections of the eye, including keratitis, endophthalmitis, and blepharitis, represent a challenging class of ocular diseases due to their potential for vision loss and the limited efficacy of existing treatments. These infections are caused by a range of pathogenic fungi, such as Aspergillus, Candida, and Fusarium species, and often require long-term therapeutic intervention. Conventional topical antifungal therapies, such as eye drops and ointments, suffer from poor ocular bioavailability due …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 101–109 Read article
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The Development and Assessment of a Polyherbal Powder Formulation for the Treatment of Fungal Infections
Abstract: A poly-herbal powder drink was made in the current investigation utilizing a variety of conventional herbs that have been shown to have nutritional benefits. Tinosopra cordifolia, Cinnamomum verum, Zingiber officinale, Thymus sperpyllum, and menthe were chosen as the main components because they are commonly used in summer home routines and have a long history of providing a refreshing, cooling, and energizing effect. Following several tests, the final formulation's composition was …
Published in Research & Reviews : Journal of Herbal Science · Vol. 11, Issue 3, 2022 · pp. 1–21 Read article
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Topical Luliconazole for the Management of Fungal Infections: A Review
Abstract: Luliconazole, an antifungal agent of the imidazole class, possesses a distinctive structure where the imidazole component is fused with the ketene dithioacetate configuration. It exists in its R-enantiomer form, which exhibits greater antifungal efficacy compared to lanoconazole, a compound comprising a racemic blend. Strong action is shown by luliconazole against filamentous fungi, such as dermatophytes. The pharmacokinetic characteristics of dermatophytes, such as Trichophyton rubrum and Microsporum gypseum, help explain why …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 1–6 Read article
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Review of the Antifungal Drug Luconazole for the Treatment of Skin Infections
Abstract: Many U.S. researchers are still working on a broad-spectrum imidazole antifungal called Luliconazole to treat dermatophytic skin and nail infections. The in vitro activity of luliconazole against filamentous fungi, including dermatophytes, is among the highest of any antifungal drug tested to date. The unique molecular characteristics of a 10% solution of Luliconazole make it possible for the drug to quickly reach fungicidal concentrations in the nail unit, allowing it to …
Published in Journal of Catalyst & Catalysis · Vol. 9, Issue 2, 2022 · pp. 13–19 Read article
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Clinical Fusariosis in India: Taxonomy, Pathogenesis, and Therapeutic Challenges
Abstract: Fusarium species are emerging opportunistic pathogens in humans, responsible for a wide spectrum of infections ranging from superficial keratitis and onychomycosis to life-threatening disseminated disease in immunocompromised hosts. Historically regarded as plant pathogens and environmental saprophytes, these hyaline moulds have become clinically relevant with the increasing use of intensive chemotherapy, haematopoietic stemcell and solidorgan transplantation, and widespread use of broadspectrum antibiotics and corticosteroids. In India, Fusarium assumes particular importance due …
Published in International Journal of Pathogens · Vol. 3, Issue 2, 2026 Read article
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Formulation And Evaluation Of Itraconazole Loaded Solid Lipid Nanoparticles For Tinea Cruris:A Promising Approach To Combat Antifungal Drug Resistance
Abstract: A fungal infection of the skin is among the most prevalent dermatological conditions worldwide. When used topically, gel formulations are among the best dose forms for treating skin infections. A promising method to reach the deeper layers of the skin and improve itraconazole (ITZ) permeability through the stratum corneum is nanotechnology. The production of ITZ-loaded nanoparticles (ITZ NPs) was accomplished through the evaporation emulsion method, and subsequently, these nanoparticles were …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 10, Issue 3, 2023 · pp. 22–28 Read article
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Clinicians’ role in the prevention and management of neonatal candidiasis in Punjab: challenges and opportunities.
Abstract: Background: Neonatal candidiasis is a growing concern in Punjab, particularly among newborns in neonatal intensive care units. The increasing prevalence poses significant risks to neonatal health, highlighting the need for effective management and prevention strategies.Objective: This study aims to explore the role of clinicians in preventing and managing neonatal candidiasis in Punjab while identifying the key challenges they face in clinical practice.Methods: A structured questionnaire was distributed to 350 clinicians, …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 26–33 Read article
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Mucormycosis during Second Wave of COVID-19
Abstract: Adding more burden to such a challenging situation, mucormycosis, an invasive fungal infection, has seen a sudden rise in the number of COVID-19 patients. The second wave affects Indians greatly with a mysterious fungal infection. Here, we are reviewed the clinical pathogenesis, signs and symptoms and treatment. The findings here showed that the use of immunosuppressants to combat COVID-19 also increases the risk of contracting mucormycosis. Patients suffering from hyperglycemia, …
Published in Research and Reviews : A Journal of Immunology · Vol. 12, Issue 1, 2022 · pp. 35–45 Read article
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Formulation, Evaluation, and Stability Studies of a Topical Clotrimazole and Zinc Oxide Suspension with Enhanced Skin Protective Properties
Abstract: Background: Clotrimazole is a well-known antifungal agent frequently used in the treatment of various superficial fungal infections, while Zinc Oxide is a widely accepted skin protectant with soothing, astringent, and antimicrobial properties. Combining these agents in a topical suspension offers a dual therapeutic approach, enhancing both antifungal efficacy and skin protection. Objective: The objective of this study was to formulate, evaluate, and conduct stability studies on topical suspensions containing Clotrimazole …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 3, 2025 · pp. 22–31 Read article
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Innovative Antifungal strategies: Terbinafine hydrochloride in Niosomal carriers
Abstract: Onychomycosis, an infection caused by fungi that affects fingernails or toenails, causes the nails to grow, separate from the nail bed, and become discoloured. While anybody can get, those with weakened immune systems, children and the elderly are especially susceptible. Present study was related to formulate an effective nail lacquer that would treat onychomycosis by utilizing Terbinafine hydrochloride. In this study, niosomes of a medication called terbinafine hydrochloride, an antifungal …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 · pp. 1–16 Read article
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Formulation and Evaluation of Antibacterial, Antifungal Cream of Garlic Oil
Abstract: Plan: The main aim of our research was to develop a novel cream formulation consisting of garlic oil for the treatment of secondary skin infections. Prologue: Topical route is most suitable route for skin infections. The development of topical drug delivery systems designed to have systemic effects appears to be beneficial for a number of drugs on account of the several advantages over conventional routes of drug administration. Methodology: A …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 6, Issue 1, 2019 · pp. 10–13 Read article
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CHARACTERIZATION, VIRULENCE TESTING AND ANTIFUNGAL SUSCEPTIBILITY PATTERN OF VARIOUS CANDIDA SPECIES AT TERTIARY CARE CENTRE, AMRITSAR
Abstract: IntroductionSerious fungal infections particularly Candida infection have increased in recent years as a consequence of increased immunosuppression associated with HIV infection, organ and tissue transplant and aggressive treatment for malignancies and autoimmune diseases. Present study was conducted to Characterize various Candida species isolated from various clinical samples, their virulence testing by biofilm production and antifungal susceptibility pattern.Settings and Design:A prospective observational study was conducted from September 2014 to June 2016 …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 2, 2019 · pp. 1–5 Read article
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Phytol—An Unsaturated Alcohol Acting as Vital Biomarker
Abstract: Phytol is a home-grown, phytochemical phytoconstituent which is generally spread in the nature. Phytol is a spread-chain, unsaturated liquor which is available in all plants as a constituent of chlorophyll. Phytol is discovered to be confined from the plant Alternanthera philoxeroides. Phytol is an acyclic alcohol of diterpene regularly accessible in fundamental oils of certain fragrant plants, such as Lantana radula and Cleome serrate. Properties such as cytotoxic, mitigating, against …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 10, Issue 3, 2020 · pp. 6–11 Read article
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Antibacterial and Antifungal Activities of Mirabilis jalapa of Indian Origin
Abstract: The in vitro antimicrobial activity of Mirabilis jalapa leaf extract was studied against selected pathogenic and non-pathogenic microorganisms Escherichia coli, Bacillus subtilis, Klebsiella pneumoniae, Penicillium chrysogenum, Auriparus flaviceps and Trichoderma viridae by using agar diffusion and broth dilution methods. Leaves were extracted using solvents petroleum ether, chloroform and methanol. Among the solvents tested, petroleum ether and chloroform extracts showed good antimicrobial activity against the selected pathogens. The growth inhibitors were …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 2, Issue 2, 2012 · pp. 1–10 Read article
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NEWEST RESEARCH ON FUNGAL MEDICATIONS
Abstract: Mycosis is a disorder brought on by mould or yeast, commonly known as a fungal infection. Although fungi (plural of fungus) can spread diseases to the mouth, throat, lungs, urinary tract, and many other regions of the body, skin and nails are the most common sites for fungal infections. You will experience various symptoms depending on the kind of fungus infection you have and where it is on your body. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 13, Issue 2, 2023 · pp. 18–26 Read article
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Dermatophytoses: Taxonomy, Pathogenesis, Diagnosis, Resistance, and Management.
Abstract: Dermatophytes, belonging to the family Arthrodermataceae, are keratinophilic fungi responsible for superficial mycoses. Dermatophytoses affect the skin, hair, and nails globally. Over the last few years, dermatophytic infections have seen a sharp rise in India, with the main causative agent being antifungal-resistant Trichophyton mentagrophytes genotype VIII. This review provides a detailed overview of dermatophytoses, including taxonomy, pathogenesis, epidemiology, diagnosis, and treatment. Dermatophytes belong to the kingdom Fungi, family Arthrodermataceae, with …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 28–37 Read article
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Antifungal Susceptibility Pattern of Candida Species Isolates from Dehradun City Hospitals
Abstract: The present investigation on the topic entitled “Antifungal susceptibility analysis of Candida species isolates from Dehradun City hospital.” was accomplished in the Doon University Microbiology laboratory (P.G.) and Hospital, Dehradun, Uttarakhand, during the period of February 2021 to July 2021. A total of 42 clinical samples were collected from patients, suspected of candidiasis from Dehradun city hospitals. Clinical samples were collected from oral cavity, blood, vaginal fluid and urine of …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 1, 2024 · pp. 12–29 Read article
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Antifungal Susceptibility Pattern of Candida Species Isolates from Dehradun City Hospitals
Abstract: The present investigation on the topic entitled “Antifungal susceptibility analysis of Candida species isolates from Dehradun City hospital.” was accomplished in the Doon University Microbiology laboratory (P.G.) and Hospital, Dehradun, Uttarakhand, during the period of February 2021 to July 2021. A total of 42 clinical samples were collected from patients, suspected of candidiasis from Dehradun city hospitals. Clinical samples were collected from oral cavity, blood, vaginal fluid and urine of …
Published in Research and Reviews : A Journal of Immunology · Vol. 12, Issue 2, 2022 · pp. 12–28 Read article
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Advanced Ointment Formulation: An Insightful Review of Innovation and Efficacy
Abstract: This review provides an in-depth exploration of the evolution of ointment formulations, particularly considering the increasing prevalence of fungal infections and the growing demand for effective antifungal treatments. Traditional ointment formulations, while useful, often face significant challenges, such as inadequate penetration into the skin, poor bioavailability, and undesirable textures that limit their efficacy. As a result, there has been a shift toward more advanced, innovative formulations that aim to address …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 1, 2025 · pp. 14–23 Read article