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20 articles for “Anti-hypertensive drugs”
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Comparison of Prescribing Pattern of Anti-hypertensive Drugs and the Level of Control Achieved in Type 2 Diabetes Patients between Primary and Tertiary Care Hospitals
Abstract: Hypertension is a common co-morbidity of diabetes affecting majority of people with diabetes, also a major risk factor for coronary vascular disease and microvascular complications such as retinopathy and nephropathy. To compare prescribing pattern of anti-hypertensive drugs and the level of control of hypertension achieved in type 2 diabetes patients in primary and tertiary care hospitals. Fifty patients each with type 2 diabetes and hypertension (fulfilling JNC 7 criteria for …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 4, Issue 2, 2014 · pp. 1–4 Read article
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The Reaction About Anti-Hypertensive Drugs According to Plasma Renin-Aldosterone States
Abstract: With recent studies, hypertension has not only a simple pathophysiology, thus it can classify details more about and establishing drug therapy strategies compatible with it is a very important method to improve the organ predictive of patients. The purpose of this study is to compare the responsibility of some anti-hypertensive drugs in hypertensive patients according to plasma renin-aldosterone levels, which becomes the background factor of hypertension. We investigated 71 hypertensive …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 14–23 Read article
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Impact of Various Front-line Hypertensive medication on Blood Pressure Control During Maximum Exercise Testing in Coronary Artery Disease Patients
Abstract: It has long been known that blood pressure (BP) and cardiovascular morbidity are related. It is acknowledged that blood pressure during activity may serve as a more reliable indicator than resting blood pressure, which might not accurately reflect blood pressure at other times. Goals: 1) To assess how blood pressure behaves during physical activity in individuals with coronary artery disease (CAD) whose hypertension is managed with first-line antihypertensive medications. 2) …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 37–41 Read article
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Carica papaya Linn.: A review on Nutritional and Medicinal Value of Papaya
Abstract: Papaya (Carica papaya Linn.) is a popular fruit tree in the tropical part of the world. It is a delicious, sweet fruit with a pleasant aroma. The papaya is consumed worldwide as a fresh fruit and vegetable. which is healthy for humans because all parts of the plant, including fruit, stem, bark, peel, fruit, seeds, and pulp, have medicinal properties. Papaya also has nutritional value and is also used as …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 67–75 Read article
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Formulation Development and Evaluation of Sublingual Tablets of Enalapril Maleate Using Co-processed Superdisintegrants
Abstract: Enalapril Maleate is anti-hypertensive drug and its oral bioavailability is 40%. Sublingual tablets of Enalapril Maleate were prepared to improve its bioavailability, to avoid pre-systemic metabolism and hepatic first pass elimination. Tablets were prepared by wet granulation technique using two different superdisintegrants KYRON-T-314 and INDION-414 in the different ratio (1:1, 1:2 and 2:1) by co-processing and physical mixing. FTIR (Fourier transform infrared spectroscopy) and DSC (differential scanning calorimetry) spectroscopic studies …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 5, Issue 3, 2014 · pp. 24–39 Read article
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Knowledge, Practice and Attitudes Towards Lifestyle Modifications Regarding Hypertension in Women
Abstract: Hypertension (HTN) is a major precipitating factor for cardiovascular diseases, kidney disease and stroke. Despite the intensive use of pharmacological agents, a rise in poorly controlled hypertensive cases has been observed due to the underutilization of therapeutic lifestyle changes (TLC) treatment approach. Objective of the study is to assess the knowledge, practice and attitudes of women towards lifestyle therapeutic modifications regarding hypertension among women in a third world country in …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 12, Issue 2, 2022 · pp. 11–21 Read article
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Patterns of Antihypertensive Drug Utilization in a West Indies University Teaching Hospital
Abstract: Objective of this study was to determine the prescribing patterns of antihypertensive medications in specialty outpatient clinics in a tertiary care hospital of a Caribbean developing country. A retrospective prescription-based survey was conducted in the renal and cardiac outpatient clinics during the period September to December 2006. Data recorded included demographic data, antihypertensive and other drugs prescribed, duration of prescription, adverse drug reactions and side effects. A total of 285 …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 5, Issue 1, 2014 · pp. 26–34 Read article
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Review Article– An Overview on The Different Management Techniques of Hypertension Condition
Abstract: Abstract This article provides an overview on the tablet dosage forms and its benefits as well as disadvantages, the main changes that have taken place in the diagnosis and management of hypertension over the past decade. The approach to the management of hypertension includes necessary life style modifications and step wise escalation process in the pharmaco-therapeutic management thereof. Thiazide diuretics are still being promoted by most guidelines to be the …
Published in Trends in Drug Delivery · Vol. 7, Issue 2, 2020 · pp. 20–25 Read article
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Treatment and management of Hypertension using Combinatorial therapy: A recent Approach
Abstract: One of the most frequent and widespread illnesses is hypertension. Nowadays, several medications are used to treat hypertension but are implicated in having some severe side effects. So, to overcome these side effects, there is the usage of a combination of drugs based on lesser side effects and an increase in efficacy or therapeutic goals. Although the first pharmacological therapy impacts long-term results, lowering blood pressure is the most critical …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 12, Issue 3, 2022 · pp. 1–7 Read article
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An Overview on Resistant Hypertension: Pathophysiology, Diagnosis, and Management
Abstract: Hypertension is a universal health issue, which is an utmost attributor for the weight of cardiovascular diseases when BP leftovers resistant or stubborn to therapeutic events. Notwithstanding the progressive growth in the antihypertensive therapy, the incidence of resistant hypertension is assessed to be less than 5% of the hypertensive inhabitants. Resistant hypertension is well-defined as blood pressure that leftovers over head the goal line in meanness of the simultaneous usage …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 10, Issue 1, 2021 · pp. 16–30 Read article
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Needle Choice in Spinal Anaesthesia: Is the 25-Gauge Whitacre Superior to the Quincke in Reducing Post-Dural Puncture Headache
Abstract: The process known as endotracheal intubation involves inserting a synthetic tube into the trachea and inflating the former's cuff to create an airtight seal. Of all the specialised masks in the LMA family, the PLMA is the most intricate. The cuff, the airway tube, the drain (gastric access) tube, and the inflation line with pilot balloon are its four primary components. This drain tube aids in identifying mask malposition and …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 Read article
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Needle Choice in Spinal Anesthesia: Is the 25-Gauge Whitacre Superior to the Quincke in Reducing Post-Dural Puncture Headache
Abstract: The process known as endotracheal intubation involves inserting a synthetic tube into the trachea and inflating the former’s cuff to create an airtight seal. Of all the specialized masks in the LMA family, the PLMA is the most intricate. The cuff, the airway tube, the drain (gastric access) tube, and the inflation line with pilot balloon are their four primary components. This drain tube aids in identifying mask malposition and …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 · pp. 22–30 Read article
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Docking Studies on Some Benzimidazole and Triazole Analogues as Antihypertensive Agents
Abstract: The incidence rate of hypertension continues a phenomenal rise and so, there is a growing need to identify novel therapeutic agents with improved efficacy and reduced side effects. In these circumstances, drugs acting on multiple targets could offer superior efficacy profiles compared with single target drugs. Some molecules have been designed using rational drug design approach and evaluated by performing docking studies. Targets used were an angiotensin-converting enzyme, angiotensin receptor, …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 5, Issue 2, 2018 · pp. 37–39 Read article
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Multifarious Pharmacotherapeutic Perspectives of Some Natural Bromophenol Compounds: In silico Enzyme Inhibitory Potentials
Abstract: The process of drug discovery, design, and development often designated as 3Ds has played enormous role in modern era. The present research investigation includes in silico exploration of possible pharmacological potentials of bromophenol compounds by the aid of Schrodinger Maestro 9.1 software against six pharmacotherapeutic targets; Dipeptidyl peptidase (anti-diabetic), Angiotensin-1-Converting Enzyme (anti-hypertensive), Cyclin-Dependent Kinase-5 (anti-cancer), Protein kinase C (anti-cancer), Lipoxygenase-5 (anti-inflammatory), and Cycloxygenase-2 (anti-inflammatory). The docking scores, referred to as …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 6, Issue 2, 2019 · pp. 24–29 Read article
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A Systematic Review of the Herbal Medicinal Plants With Anti-Obesity Potential
Abstract: Obesity is a chronic, multifactorial metabolic condition characterized by abnormal fat accumulation. It is mainly driven by the intricate influence of genetic, environmental, hormonal, metabolic and lifestyle determinants. The burden of obesity has risen considerably over the past few years, making it one of the major health concerns in both developed and developing countries alike. The rapid increase globally in obesity prevalence is linked with numerous health complications such as …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 · pp. 31–38 Read article
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An Approach to Treat Corvid-19: An Opinion to Use Angiotensin Converting and 4-Dipeptidyl Peptidase Enzymes Inhibitors
Abstract: Abstract Coronavirus (CoV) attach the cell surface and enter the host cell via interaction with angiotensin converting enzyme receptor. Viral replication induces dysregulation of the autophagy process and interferes with the natural function of the lysosomes. Antimalarial drugs, including chloroquine and hydroxychloroquine through their lysosomotropic and autophagy inhibiting effects may be useful in the management of CoV infections. Among the people who at risk of developing CoV infections are hypertensive …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 7, Issue 2, 2020 · pp. 8–12 Read article
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Tulasi (Ocimum sanctum Linn.) – A Drug Review
Abstract: Tulasi (Ocimum sanctum Linn. belonging family Lamiaceae) is described as a sacred and useful medicinal plant in ancient literature. It is derived from ‘Sanskrit,’ which means "the incomparable one. Tulasi leaves have Katu- Kashaya Rasa, as well as Laghu, Ruksha and Tikshna Guna and Ushna Virya. It has proven pharmacological actions such as antioxidant, immune-modulatory, antipyretic, anticancer, chemo-preventive, radio-protective, anti-hypertensive, cardio protective, antimicrobial activity and many more. The present article …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 7, Issue 2, 2020 · pp. 14–22 Read article
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Cardiotoxicity Associated with Tyrosine Kinase Inhibitors in Philadelphia Chromosome-Positive Leukemias: An Overview of Mechanisms, Clinical Implications, and Management Strategies
Abstract: Tyrosine kinase inhibitors have greatly enhanced the outlook for individuals diagnosed with Philadelphia chromosome-positive leukemias, including chronic myeloid leukemia and acute lymphoblastic leukemia. However, these therapeutic agents are associated with Cardiotoxicities and can manifest as left ventricular dysfunction, which may progress to heart failure, along with electrocardiographic abnormalities, dysrhythmias, hypertension, myocardial ischemia, and thromboembolic events. The unclear frequency of drug-induced cardiovascular complications, coupled with uncertainties regarding their reversibility and long-term …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 18–24 Read article
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Decompensated Liver Failure and Acute Renal Failure in a Patient with Chronic HBV,HCV, and HIV Infections
Abstract: This case study focuses on a 30-year-old male patient suffering from decompensated liver failure and acute renal failure, complicated by chronic hepatitis B (HBV), hepatitis C (HCV), and HIV/AIDS. Presenting with severe abdominal pain, nausea, and general weakness, the patient had a history of alcohol and intravenous drug use, leading to chronic liver disease and acute renal failure. Despite aggressive interventions, including intravenous antibiotics and fluid therapy, his condition worsened …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 17–23 Read article
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Over the Counter Drugs Use by Libyan Women before and during Pregnancy
Abstract: Information on the safety of drugs is particularly important during pregnancy because pregnant women may have chronic diseases requiring medical intervention, for example, epilepsy, diabetic mellitus, or asthma. Alternatively, they develop pregnancy-induced problems such as hypertension or diabetes. For both situations, drug use in pregnancy is necessary. To avoid all drugs in pregnancy is unreasonable and may be dangerous. The main aim of this study was to measure the frequency …
Published in Trends in Drug Delivery · Vol. 8, Issue 1, 2023 · pp. 14–21 Read article