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622 articles for “potential treatments”
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Unveiling Nature’s Potential: In Silico Exploration and Identification of Herbal Remedies for Major Depressive Disorder Through Molecular Interaction Studies
Abstract: Major depressive disorder (MDD), a globally discussed mental health condition, has drawn significant attention because of its unique and intricate nature. This is marked by the enduring presence of negative emotions stemming from a lack of interest, diminished self-esteem, and excessive rumination. Despite the widespread availability of various antidepressant medications, their effectiveness is hindered by low response rates, prolonged treatment durations, and the prevalence of side effects, such as headaches, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 54–62 Read article
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Innovations in Tuberculosis Management: Advancements in Drug-Resistant TB Treatment and Rapid Diagnostics
Abstract: Tuberculosis (TB) remains one of the deadliest infectious diseases worldwide, exacerbated by the increasing prevalence of drug-resistant strains, such as multidrug-resistant (MDR-TB) and extensively drug-resistant TB (XDR-TB). Despite advancements in first-line and second-line treatments, resistance to conventional antibiotics has complicated therapeutic strategies, necessitating novel approaches. This mini review explores emerging advancements in TB treatment, including gene editing technologies, such as CRISPR, which offer potential for precise targeting of drug-resistant bacterial …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–7 Read article
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An Overview on the Management cum Treatment of Nephropathy in Type-1 Diabetes Mellitus
Abstract: The motive of this review is to keep updated with the medical nonfictions, the projected early natural arrangement of diabetic nephropathy, the theories behind the root of its pathogenesis pathophysiology, diagnosis and its supervision. Type 1 diabetes is an autoimmune disease characterized by advanced destruction of pancreatic beta cells by genetic and environmental factors which primes to an absolute necessity of insulin for survival and conservation of health; while Diabetic …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 3, 2020 · pp. 19–38 Read article
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Neuropharmacological Mechanisms of Psychedelics: Advancing Treatment Strategies for Mental Health Disorder
Abstract: The resurgence of interest in the therapeutic potential of psychedelic drugs has caused a major upheaval in the field of psychiatry in recent years. This review's main goal is to thoroughly examine the possible benefits of psychedelic drugs in the field of psychiatry, with a focus on how they might be used as psychotherapy aids. Given their widespread use in therapeutic settings, clinical trials involving MDMA, psilocybin, ketamine, and LSD …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 67–79 Read article
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Striking A Balance: Ethical Guidelines for A.I. Integration in Mental Health Services
Abstract: Introduction: Artificial Intelligence (AI) integration in mental health services presents opportunities and challenges. This study examines ethical considerations and proposes guidelines for responsible AI implementation in mental healthcare. The rapid advancement of AI technologies has sparked both excitement and concern within the mental health community, necessitating a thorough examination of their potential benefits and risks. By addressing these ethical considerations, this research aims to contribute to the development of a …
Published in International Journal of Behavioral Sciences · Vol. 2, Issue 1, 2025 · pp. 8–15 Read article
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Sustainable Membrane Technologies for Environmental and Industrial Applications: A Review
Abstract: Membrane-based technologies have become indispensable in addressing global environmental and industrial challenges, including water scarcity, pollution control, and energy efficiency. While conventional membranes provide high selectivity and process efficiency, their sustainability is limited by factors such as fouling, high energy consumption, and end-of-life waste management. Recent advances in material science, nanotechnology, and bio-inspired design have led to the emergence of sustainable membranes with improved durability, lower environmental footprint, and broader …
Published in International Journal of Membranes · Vol. 2, Issue 2, 2025 · pp. 7–12 Read article
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Exploring Recent Advancements in Nanomedicine for Tumor Microenvironmental Tissue Engineering
Abstract: The combination of tissue engineering and nanomedicine is transforming cancer treatment by offering creative ways to get around problems with conventional therapies. Recent developments in nanomedicine are examined in this review, with an emphasis on how they might be used to comprehend and control the tumor microenvironment (TME), a dynamic and complex environment that has a major impact on the course of cancer and the effectiveness of treatment. Targeted interactions …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 122–136 Read article
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Hematopoietic Stem Cells: Sources and Therapeutic Potential for Autoimmune Diseases and Cancer
Abstract: Hematopoietic stem cells (HSCs) are a group of multipotent adult stem cells that are responsible for lifelong production of all types of functional blood cells comprising myeloid (monocytes, macrophages, granulocytes), megakaryocytes/platelets, red blood cells (erythrocyte), T-cells, B-cells, natural killer (NK) cells, mast cells and dendritic cells (DCs). HSCs have the capacity for self-renewal and differentiation into various tissues. These remarkable properties of HSCs make them an ideal tool for tissue …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 1, Issue 3, 2012 · pp. 6–14 Read article
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Magnetic and Radioactive Nanoparticles for Improved Theranostics and AI Assisted Radiation Therapy
Abstract: Nanoparticles based therapeutic and theranostics technique is becoming an active area of research in nanomedicine. The sensitivity, biocompatibility, and stability of magnetic and radioactive nanoparticles determine their functionality. This research highlights the impacts of magnetic and radioactive nanoparticles on therapeutic techniques namely, cell therapy, gene therapy, and tissue regeneration. Then, it is intended to brief a principal role of these therapeutic techniques to envisage theranostics medicine and radiation therapy using …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 2, 2025 · pp. 10–21 Read article
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Drugs for Alzheimer’s Disease from Salix Alba Discovered Computationally Utilizing Virtual Screening and Docking against 1b41 Protein
Abstract: Objective : The of this research is to evaluate the feasibility of using molecular docking techniques to identify novel acetylcholinesterase, a key enzyme implicated in the pathogenesis of Alzheimer’s disease, a neurodegenerative disorder with a gradual but steady progression to death, due to the gradual accumulation of beta-plaques and neurofibrillary tangles, as well as a decline in acetylcholine levels. Due to its function in converting acetylcholine into acyl and choline …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 07–19 Read article
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The Current State of Huntington's Disease Treatment: An Overview of Palliative Care and Symptom Management
Abstract: Huntington's disease (HD) is a neurodegenerative ailment that adversely affects the basal ganglia and the cortex of the brain. Although there is no recognized cure for HD, symptomatic relief and therapeutic management of the condition have improved over the course of time. This review paper provides an up-to-date overview of the current treatment options and symptom management strategies utilized in the care of HD patients. Additionally, it highlights the existing …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 Read article
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Exploring the Role of MAPK3 in Major Depressive Disorder: Molecular Docking, Dynamics, and Binding Free Energy Analysis of Natural Compounds as Alternatives to Conventional Drugs
Abstract: Major Depressive Disorder (MDD) is a prevalent neuropsychiatric disorder with limited treatment efficacy and significant side effects associated with conventional antidepressants. Recent studies have highlighted the role of mitogen-activated protein kinase 3 (MAPK3) in the mechanisms underlying MDD, positioning it as a potential target for the development of novel therapeutic drugs. In this study, we employed various computational approaches to explore natural compounds as viable alternatives to synthetic antidepressants. Researchers …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 53–68 Read article
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The Role of Surface Treatments on Mechanical and Interfacial Shear Strength of Pineapple Leaf Fibers
Abstract: Natural fibers are seen as having potential application as reinforcing agents in polymer composite materials due to their main advantages, which include moderate strength and stiffness, low cost, and being an environmentally beneficial, degradable, and renewable material. They are susceptible to absorbing moisture because of their innate hydrophilicity, which can weaken or plasticize the adherence of the fibers to the surrounding matrix and impact the performance of composite materials employed …
Published in Journal of Materials & Metallurgical Engineering · Vol. 12, Issue 3, 2022 · pp. 18–28 Read article
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Pharmacoinformatic Based Screening Of Phytocompound Epigallocatechin Gallate To Identify As A Potential Bcl-2 Inhibitor
Abstract: Objectives: The B-cell lymphoma-2 (Bcl-2) is a protein that is particularly though to be involved in preventing apoptosis. Bcl-2 family members also essential for cancer survival, and its over expression has been linked to tumor genesis, development and resistance to anticancer treatments. The Bcl-2 family of members that inhibit apoptosis is a promising target for the creation of anticancer drugs. Methods: The study was based on computational approach using different …
Published in International Journal of Bioinformatics and Computational Biology Read article
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Innovative 3D Printed Cell Scaffolds with Magnetized Nanocomposites for Targeted Cancer Therapy Drug Delivery
Abstract: In recent years, scaffolds have gained increasing attention in the field of tissue engineering, especially in cancer treatment. Nanocomposite scaffolds have emerged as promising candidates for delivering drugs to cancer cells. 3D printing technology has enabled the fabrication of customized scaffolds with precise pore size and complex geometries. This study explores the development of 3D printed scaffolds of nanostructured made of graphene oxide and Poly-Caprolactone (PCL) nanocomposites, which can be …
Published in Journal of Polymer & Composites · Vol. 11, Issue 3, 2023 · pp. 48–55 Read article
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Grey Water Recycling
Abstract: Domestic grey water recycling and reuse in residential buildings have been comprehensively examined. It is estimated that recoverable grey water can account for approximately 35% to 40% of total household water demand, highlighting its substantial potential to reduce freshwater consumption in domestic settings. A comprehensive worldwide review of grey water recycling and reuse practices has been reported, highlighting the increasing importance of sustainable water management in both developed and developing …
Published in Journal of Water Pollution & Purification Research · Vol. 13, Issue 1, 2026 · pp. 69–77 Read article
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Targeting TNFSF4 in the Management of Systemic Lupus Erythematosus
Abstract: Systemic lupus erythematosus (SLE) is a multifaceted autoimmune disorder that remains a significant challenge for both healthcare providers and researchers. Despite advances in understanding its mechanisms, finding effective therapies is still difficult. This review highlights a potential therapeutic target in SLE research: tumor necrosis factor superfamily member 4 (TNFSF4), also referred to as OX40L. We explore how TNFSF4 contributes to SLE development, looking at its role in immune system regulation …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 6–14 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Sustainable Biomedical Applications
Abstract: Liposomal drug delivery has evolved into a viable approach in modern pharmacology thanks to its enhanced bioavailability, reduced systemic toxicity, and targeted drug release. Conventional liposomes have limited stability, medicine leakage, and short circulation times among other problems. Overcoming these limits, the inclusion of nano-polymers into liposomal formulations has transformed medication delivery. Thorough research has been done on the potential of nano-polymers including chitosan, hyaluronic acid, polyethylene glycol (PEG), and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 420–432 Read article
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Utilization of Banana Peel Biopolymer as a Natural Coagulant for Wastewater Treatment: A Sustainable Approach to Bio-Composite Applications
Abstract: This study explores an eco-innovative approach to wastewater treatment by utilizing banana peel powder (BPP) as a sustainable, low-cost bio-coagulant. Although effective, conventional chemical coagulants like aluminum sulfate and synthetic polymers are often non-biodegradable, toxic, and economically burdensome, particularly in decentralized or low-resource settings. In contrast, BPP—an agro-waste material rich in bioactive functional groups such as hydroxyl, carboxyl, and phenolic compounds—provides a renewable and environmentally friendly alternative. To enhance its …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 106–115 Read article
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Metal corrosion prevention control with uses of sol-gel coatings
Abstract: The potential for sol-gel generated films to replace methods for pre-treating metal surfaces with chromate is very high. Metallic and organic paint can be painted on with good adherence thanks to inorganic sol-gel generated coatings. Their significant crack-forming propensity prevents them from offering appropriate corrosion protection. A thicker, more flexible, functionalized film is produced with improved compatibility to various organic top coatings when an organic component is added to an …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 9, Issue 2, 2022 · pp. 22–26 Read article