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441 articles for “functionalization”
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In Silico Drug Design for Mycobacterium tuberculosis and Development of Host–Pathogen Interaction Network and Molecular Docking Procedures
Abstract: Objective: A leading cause of illness is the contagious disease tuberculosis (TB), this infection with Mycobacterium tuberculosis complex (MTBC) particularly M. tuberculosis and M. africanum, is what causes tuberculosis. Diverse receptor proteins (mycobacterial proteins) with various 3D structures and functions were evaluated to access the multi-domain antimycobacterial action of ligands. The specific receptor proteins PDB ID: 3PTY, PDB ID: 4OW8, PDB ID: 5KWA, and PDB ID: 3ZXR, were opted for …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 1–19 Read article
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In Silico Prediction of Multitarget Mechanism of Quinoline and Its Analogs on Phosphoinositide-3-Kinase Pathway Proteins
Abstract: Objective: Phosphoinositide 3-kinases (PI3Ks), the target of rapamycin (PI3K/Akt/mTOR, PAM), are a family of enzymes that play a role in the growth, proliferation, differentiation, motility, survival, and intracellular trafficking of cells, all of which are essential for healthy cellular function and are also connected to cancer. In this study, quinoline and its derivatives were employed to analyze its inhibition activity on the phosphoinositide-3-kinase pathway. Methods: In this work, eight phytocompounds …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 57–76 Read article
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"Achieving Sustainability Through Building Adaptationt"
Abstract: Building adaptation has a significant impact on sustainable development. There are various aspects of building obsolescence that affect the quality and performance of the building after its useful lifecycle, which include reduced environmental, economic, functional and social performance. Timely and effective building adaptation of the buildings which are facing obsolescence can extend its effective lifespan and this can provide considerable economic, environmental and social benefits, making it a sustainable alternative …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 1, 2023 · pp. 27–32 Read article
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Impacts of Green Facades in Modern Era
Abstract: Modern architecture was an architectural movement or style centred on cutting-edge construction technologies, particularly the use of reinforced concrete, glass, and steel. The foundational goal of 21st century architecture is to create better structures that are inherently sustainable by utilising better materials and technologies. Facades are the outermost covering of a building which have the maximum interaction with the environment. A wall that is completely or partially covered with vegetation …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 1, 2023 · pp. 44–57 Read article
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Analysis of critical constraint factors affecting the performance of Transportation projects
Abstract: Infrastructure is a country's biggest source of economic growth, which is made up of a variety of facilities and processes. It includes all the amenities and services required for urbanization, economic expansion, improved quality of life, and thriving companies. Transportation is one of the most important industries for any nation's economy, but constraints exist in all working environments. A construction constraint is a condition that makes it difficult to achieve …
Published in International Journal of Urban Design and Development · Vol. 1, Issue 1, 2023 · pp. 54–78 Read article
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The Nursing Perspective: Emerging Competencies in Midwifery and Neonatal Care
Abstract: A skilled attendant is a qualified healthcare practitioner, such as a midwife, doctor, or nurse, who has received appropriate education and training to effectively handle uncomplicated pregnancies, childbirth, and the immediate postnatal period. They are equipped to identify, manage, and refer any complications that may arise in women and newborns. Skilled attendants have the necessary knowledge and skills to manage normal pregnancies and childbirth, and their presence during delivery is …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 21–26 Read article
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Production of Disinfectant Using Aloe Vera (Aloe barbadensis miller) Plant Extracts
Abstract: This research work demonstrates the production of a disinfectant using aloe vera (Aloe barbadensis Miller) as main source of the raw material. The liquid content of the aloe vera was extracted using mechanical and unit operation mechanisms and the obtained raw material was subjected to heating to evaluate the effect of temperature on the characteristics of the physiochemical properties of pH, total ash, crude fat, fibre and protein, total carbohydrate, …
Published in International Journal of Pollution: Prevention & Control · Vol. 1, Issue 1, 2023 · pp. 17–30 Read article
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Instant Response Garbage Disposal Using Android Application
Abstract: Solid waste is a major concern for government bodies and is a consequence of development, modernization, and urbanization. It refers to anything that is not a gas or liquid and poses a serious threat to the natural environment. Solid waste is a type of refuse that can accumulate in a certain area for an extended period of time if not properly managed. The waste can persist in the environment until …
Published in International Journal of Mobile Computing Technology · Vol. 1, Issue 1, 2023 · pp. 18–24 Read article
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Management of Rotator Cuff Injury with Physiotherapy in Pre- and Post-surgery: An Overview
Abstract: The likelihood of rotator cuff tears increases with age, with total width tears occurring in roughly 25% of people in their 60s and an extra 50% of people in their 80s. Despite the fact that surgery is considered an active therapy, repeated rips at the inset place are common, particularly during progressive tears, which are common in the elderly population. Physical therapy and exercise therapy are currently receiving more attention …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 6–12 Read article
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Bone Fracture: Understanding, Therapies, and Rehabilitation
Abstract: Bone fractures are common injuries that can significantly impact an individual's quality of life. This article presents a comprehensive examination of bone fractures, encompassing their origins, categorization, and potential ramifications. This review of literature explores various therapeutic approaches and rehabilitation strategies employed in the management of bone fractures. Surgical interventions, non-surgical treatments, and rehabilitation techniques are discussed, highlighting their effectiveness in promoting healing, restoring function, and preventing complications. The article …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 24–28 Read article
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A Study to Evaluate the Effectiveness of a Structured Teaching Program on the Knowledge and Practice of Road Traffic Accident Prevention Measures Among Teenagers
Abstract: An investigation to evaluate the impact of a structured educational program on the understanding and implementation of strategies for preventing road traffic accidents among teenagers. Introduction: Accident is an accidental injury, passing or property harm happening in a grouping of occasions. Accidents don't simply occur; they are neglectfulness, indiscretion, carelessness, and flashing absence of focus. Accidents have turned into a significant reason for dismalness and mortality, particularly among the grown-ups …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 29–40 Read article
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Effects of Cluster Computing on Big Data Analysis and Network Topology
Abstract: The rapid expansion of big data has posed substantial difficulties for conventional computing systems. As a result, cluster computing has grown to be a potent method for effective large data processing. Cluster computing involves multiple interconnected nodes functioning as a unified system, pooling together their processing, storage, and memory resources. These nodes are typically connected through high-speed networks such as ethernet or InfiniBand, facilitating efficient data sharing and communication among …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 1, Issue 1, 2023 · pp. 31–39 Read article
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Study of Finite State Machines as Language Recognizer
Abstract: Finite State Machines (FSMs) play a fundamental role in computer science and linguistics as language recognizers. This study presents an exploration of the principles and applications of FSMs as efficient tools for recognizing formal languages. The study delves into the theoretical foundations of FSMs and their practical implementation in various language recognition tasks. The fundamental ideas of FSMs, including as states, transitions, and input symbols, are introduced in this study. …
Published in International Journal of Data Structure Studies · Vol. 1, Issue 1, 2023 · pp. 18–24 Read article
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Designing of a Rooftop Penthouse for Indoor and Outdoor Living
Abstract: Rooftop penthouses offer an exclusive and luxurious living experience with their stunning views and outdoor spaces. The concept of rooftop living is becoming increasingly popular, especially in urban areas where space is limited. Designing a rooftop penthouse for indoor and outdoor living refers to creating a living space on the top floor of a building that provides both indoor and outdoor living areas. The design aims to maximize the use …
Published in International Journal of Urban Design and Development · Vol. 1, Issue 2, 2023 · pp. 13–24 Read article
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Knowledge and attitude of postnatal mothers towards Human Breast Milk Banking in a selected Hospital
Abstract: Background: Breast milk is universally endorsed as unique, innate and vital feed, gifted by nature for neonates. Human Breast milk banks function as stockpile for women who are incapable to provide their own breast milk to their unwell or confined infants. In Indian scenario, donation of breast milk is an emerging notion and has been introduced among few metropolises across the nation. Unavailability to breastmilk foster infants more susceptible to …
Published in International Journal of Midwifery Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 10–18 Read article
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Brain Machine Interface: A Review of Current Technologies and Future Directions
Abstract: Brain Machine Interface (BMI) is a rapidly growing field that aims to establish direct communication between the brain and an external device. This technology has the potential to restore lost motor and sensory functions in people with neurological disorders or injuries. A brain-computer interface (BCI) is a technology that converts signals from the brain into instructions for computers or other gadgets. This innovation allows individuals to engage with their surroundings …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 1, Issue 1, 2023 · pp. 14–24 Read article
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Cross-layer Solutions in WSN Routing: A Review
Abstract: WSN is a less infrastructure wireless network which is embedded with large number of Sensor Nodes (SN). Its ad-hoc manner of device distribution allows it to monitor conditions under physical and environmental scenarios. Typically, SNs in WSN are installed in a specified geographical location to monitor required information. Due to SNs’ self-configuring ability, the exploitation of target is simpler. Though, its functioning is limited with factors such as energy efficiency, …
Published in International Journal of Wireless Security and Networks · Vol. 1, Issue 2, 2023 · pp. 26–36 Read article
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Drugs for Alzheimer’s Disease from Salix Alba Discovered Computationally Utilizing Virtual Screening and Docking against 1b41 Protein
Abstract: Objective : The of this research is to evaluate the feasibility of using molecular docking techniques to identify novel acetylcholinesterase, a key enzyme implicated in the pathogenesis of Alzheimer’s disease, a neurodegenerative disorder with a gradual but steady progression to death, due to the gradual accumulation of beta-plaques and neurofibrillary tangles, as well as a decline in acetylcholine levels. Due to its function in converting acetylcholine into acyl and choline …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 07–19 Read article
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WSN with IoT Using Raspberry Pi as a Tool for Communication
Abstract: Wireless systems based on IoT have developed exponentially in various aspects. The Internet of Things (IoT) is a network in which physical devices, sensors, and other objects communicate among themselves without the involvement of humans. The WSN (Wireless sensor network) is a central component of IoT that has escalated into various applications in the real world. Many industries are turning towards industrial automation as it provides increased efficiency, reduced costs, …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 1, Issue 1, 2023 · pp. 34–42 Read article
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Detection of Pneumonia in COVID-19 Patients Using X-ray Images
Abstract: This study explores the use of chest X-ray image analysis and deep learning methods to identify pneumonia in COVID-19 patients. Due to the pandemic, Proper as well as immediate examination of COVID-19 is now essential for patient care and disease control. This study proposes a novel approach that uses convolutional neural networks (CNNs) to automatically predict pneumonia in COVID-19 patients using chest X-ray images. In this study, an X-ray of …
Published in International Journal of Radio Frequency Innovations · Vol. 1, Issue 1, 2023 · pp. 13–23 Read article