Search
539 articles for “compounding”
-
Nutraceuticals as Adjunctive Treatment in Cancer Exploring Efficacy and Mechanism of Action
Abstract: Dietary habits are a critical factor in cancer prevention, with plant-based diets rich in vegetables and fruits associated with reduced cancer risk. Nutraceuticals—bioactive compounds derived from food and supplements—have gained attention for their potential in cancer prevention and therapy. Phytochemicals such as flavonoids, polyphenols, and alkaloids exhibit anti-cancer properties through mechanisms including antioxidant activity, anti-inflammatory effects, inhibition of tumor growth, and induction of apoptosis. Key nutraceuticals include alkaloids (e.g., caffeine, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 35–45 Read article
-
Corrosion and Corrosion Protection of Unio in Carbonic Acid Medium
Abstract: Unio is a calciferous animal, and its outer surface is made of calcium carbonate. It usually happens in sources of sweet water. They create carbonic acid by absorbing carbon dioxide. It changes the pH of sweet water sources thus water becomes acidic. It develops corrosive environment for Unio. Carbonic acid interacts with Unio to form corrosion cells on the interface of Unio. This acid oxidizes calcium carbonate into calcium ions …
Published in Journal of Water Pollution & Purification Research · Vol. 12, Issue 1, 2025 · pp. 22–31 Read article
-
Study the Impact of Corrosive Pollutants on Building Materials Corrosion
Abstract: Reinforced concrete structures (RCS) may be made more resistant to corrosion by using fiber reinforced polymers (FRP). One of the primary concerns with reinforced concrete constructions is corrosion. It causes disintegration in building material components by interactions with salts, acids, and alkalis. Both within and outside of reinforced properties, pollutants and effluents accelerate disbanding. When bio-waste and building materials come into contact, microorganisms and macro organisms, grow and emit acid …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 2, Issue 2, 2024 · pp. 20–29 Read article
-
Exploring Phytochemicals from Ricinus Communis for Potential Therapeutic Applications in Rheumatoid Arthritis: An in-Silico Approach
Abstract: Aim: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by the immune system mistakenly attacking the joints, leading to swelling, discomfort, and joint deformities. Current management strategies include anti-rheumatic drugs and biologics, which have limitations. This study aims to explore the therapeutic potential of Ricinus communis (castor bean plant) phytochemicals as plant-based therapies for autoimmune conditions, like RA. Methods: Phytochemicals from Ricinus communis were retrieved using the IMPPAT database, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 32–41 Read article
-
Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
-
The Future is Smelling: Exploring the Potential of e-Nose
Abstract: The human sense of smell, a complex and often underestimated faculty, allows us to perceive the world through volatile organic compounds (VOCs). This ability to detect and differentiate between aromas, flavors, and even potential hazards has inspired the development of the electronic nose, or e-nose. More than just a novelty, e-noses are rapidly becoming sophisticated analytical tools with applications that span across numerous industries. By mimicking the biological processes of …
Published in Journal of Semiconductor Devices and Circuits · Vol. 12, Issue 1, 2025 · pp. 15–25 Read article
-
Degradation of Building Materials by Corrosive Pollutants
Abstract: Fiber reinforced polymers (FRP) is used for the corrosion suppression of reinforced concrete structures (RCS). One of the main issues with reinforced concrete constructions is corrosion. It interacts with acids, alkalis and salts to produce disintegration in building materials components. Pollutants and effluents speed up disbanding inside and outside reinforced structures. Bio-wastes come in contact of building materials to develop miro and macro-organism and these organisms release acid substances to …
Published in International Journal of Minerals · Vol. 2, Issue 1, 2025 · pp. 15–24 Read article
-
Molecular Pharmacokinetics and Structural Docking of Phenolic Acids for Targeting NF-κB Pathway Components in Inflammation and Fibrosis: A Computational Approach Toward Therapeutic Discovery
Abstract: Inflammation and Fibrosis are critical pathological processes associated with various chronic diseases, often mediated by the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway. This study investigates the therapeutic potential of phenolic acids as modulators of the NF-κB pathway, aiming to identify novel ligands that can effectively interact with key components of this signaling cascade. A comprehensive computational approach was employed, utilizing molecular docking, pharmacological screening, and post-docking …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 14–31 Read article
-
Phytochemical, Pharmacological and Toxicological Studies of Solanum americanum: A Systemic Review
Abstract: Solanum americanum, a plant widely used in folk medicine, has recently gained attention in the scientific community due to its diverse therapeutic potential. The bioactive compounds found in different plant parts, such as alkaloids, flavonoids, and tannins, have significant medicinal effects. These compounds exhibit several pharmacological properties, such as antimicrobial, anti-inflammatory, anticancer, and antioxidant effects. However, despite these medicinal benefits, some compounds show significant toxicity to the human body if …
Published in Research & Reviews : Journal of Herbal Science · Vol. 14, Issue 2, 2025 · pp. 52–62 Read article
-
Synthesis, Characterization, Biological evaluation, and in silico study of aniline derivatives
Abstract: In many hospitals worldwide, bacterial infections brought on by resistant strains are wreaking havoc, particularly in patients who are already impaired by age, disease, and other conditions. Due to the bacterial resistance, it is required to search for newer antibacterial drugs or molecules. In the current study, we aimed to develop aniline derivatives, followed by their anti-bacterial and in silico studies. Out of all the synthesized derivatives, compound 4d was …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 25–32 Read article
-
Synthesis, Characterization, Antibacterial Evaluation and Study of Organic Separation Behavior for Five Membered Ring for Pyridine Derivatives
Abstract: Imidazoles can be prepared by condensation between amines and various aldehydes and ketones. Imidazole derivatives are important compounds due to their broad biological activity and pharmacological properties, such as antifungal, antioxidant, cytotoxic, anti-inflammatory, analgesic, anti-YFV (yellow fever virus), anti-tuberculosis, and antimicrobial activity. In recent years, many studies have been conducted on the preparation of biological imidazole derivatives, especially derivatives linked to heterogeneous rings containing nitrogen or any other donor atom. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 106–121 Read article
-
Flavonoid Contents and Antioxidant Activity of an Endophytic Bacteria Associated with Medicinal Plant Humulus lupulus
Abstract: Endophytes are symbiotic microorganisms, most often bacteria or fungi, that reside and multiply within plant tissues without inducing visible signs of disease or negatively affecting the host plant. Endophytic bacteria contribute to plant development by stimulating growth, strengthening defence mechanisms, enhancing tolerance to both abiotic and biotic stresses, and facilitating improved nutrient uptake. Endophytic bacteria serve as an important reservoir of bioactive compounds, notably antioxidant molecules, that play a crucial …
Published in Research & Reviews : Journal of Herbal Science · Vol. 14, Issue 3, 2025 · pp. 1–6 Read article
-
Comparative Study of Bioactive Phytochemicals from Hexane Extract of Two Amaranthaceae Leafy Vegetables by GC-MS Method
Abstract: Amaranthus tricolor Linn and Amaranthus viridis Linn, belonging to the Amaranthaceae family, are popularly consumed leafy vegetables in India and many other countries globally. The bioactive components of Hexane extract from these two plants have been analysed using gas chromatography-mass spectrometry (GC–MS) technique. According to analysis, both species contain a total of nineteen important chemicals. Of these, ten were found in A. tricolour L. and nine in A. viridis L. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 7–17 Read article
-
Comparative Assessment of Methylparaben concentration in Cosmetic product, analyzed using Enzyme Biosensor and ultra-high-pressure liquid chromatography (UPLC): An approach towards detection of the environmental toxicant with higher accuracy and sensitivity.
Abstract: Methylparaben (MP) is one of the most widely used preservatives and is associated with a catalog of recently identified health hazards. Existing studies have also highlighted these compounds as environmental contaminants and toxicants that affect water quality and the associated microbial diversity of the habitat. The conventional methods for parabens detection is performed using chromatographic techniques, which assist in quantitative analysis of the group of compounds. However, the biggest challenge …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 2, 2025 Read article
-
Dual Nozzle 3D Printing of Basalt Fiber–Reinforced Polymer Composites
Abstract: Additive manufacturing or 3Dprinting involves building a three-dimensional object by layering materials based on a computer-created design. Generally, 3D printing using single nozzle process where as strength, quality, wastage, and post reinforcement are drawback of this system. To eliminate and to enhance strength, precise control of fiber reinforcement, good bonding, no need of secondary reinforcement the dual nozzle 3D printing is an emerging additive manufacturing technique. In this process the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 620–630 Read article
-
Molecular Docking Analysis of Phytocompounds from Ficus hispida Aagainst Epidermal Growth Factor Receptor Kinase Domain
Abstract: The Epidermal Growth Factor Receptor (EGFR) kinase domain plays a key role in cancer, as it promotes tumour growth and helps cancer cells survive, making it an important focus for developing treatments. Through comprehensive computational analysis, this study investigates the anticancer potential of phytocompounds from Ficus hispida, a medicinal plant renowned for its diverse bioactive compounds, as novel EGFR inhibitors. Molecular docking techniques using Py Rx software were employed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 Read article
-
Molecular Docking Analysis of Phytocompounds from Ficus hispida Against Epidermal Growth Factor Receptor Kinase Domain
Abstract: The Epidermal Growth Factor Receptor (EGFR) kinase domain plays a key role in cancer, as it promotes tumour growth and helps cancer cells survive, making it an important focus for developing treatments. Through comprehensive computational analysis, this study investigates the anticancer potential of phytocompounds from Ficus hispida, a medicinal plant renowned for its diverse bioactive compounds, as novel EGFR inhibitors. Molecular docking techniques using Py Rx software were employed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 48–62 Read article
-
Synthesis of Green Nanoparticles for Degradation of Cellulose
Abstract: Late advances in nano-science and technology have also prompted the advance of novel nanomaterials, which eventually increment potential eudaimonia and ecological perils. Enthusiasm for growing Earth's thoughtful ways for the mix of auriferous nanoparticles has been enlarged. The intention is to limit the negative effects of the designed methodology with artificial compounds and subordinate mixes. The abuse of assorted biomaterials for the mix of nanoparticles is a profitable methodology in …
Published in Journal of Modern Chemistry & Chemical Technology Read article
-
In Silico Pharmacological Evaluation of Certain Commercially Available Terpenoids As Αlpha-Amylase Inhibitors for The Management of Diabetes Mellitus.
Abstract: The objective of this study was to investigate the α-amylase inhibitory activity of certain commercially available terpenoids using in silico docking studies. In this perspective, terpenoids like Abietane, Artemisinin, Carvone, Cucurbitane, Ferruginol, Lupeol, Nerolidol, Retinol, Sabinene, and Zingiberene were selected. Glibenclamide, a well-known antidiabetic drug was used as the standard. In silico docking studies were carried out using AutoDock 4.2, based on the Lamarckian genetic algorithm as the working principle. …
Published in Research and Reviews : Journal of Computational Biology Read article
-
Distinctive Approaches for Improving the Aqueous Solubility of BCS Class II Drugs
Abstract: The most difficult feature of many novel chemical entities is their solubility behaviour, as 60 percent of new promising products suffer solubility limitations. This is the most common reason for novel medicine compounds failing to reach the market or performing to their full potential. The proportion of the aqueous phase when the solution is in equilibrium with the pure substance in its normal phase is referred to as aqueous solubility. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 8, Issue 3, 2023 · pp. 52–56 Read article