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494 articles for “Validation Study”
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Photochemically Assisted LC–MS Method Development and Validation for Stability-Indicating Determination of Glasdegib in Rat Plasma
Abstract: A simple, precise, and cost-effective LC–MS method was successfully developed for the determination of Glasdegib in rat plasma. The method optimization was carried out by systematically varying key chromatographic parameters, including flow rate, injection volume, analyte concentration, and mobile phase composition, to achieve optimal sensitivity and resolution. A C18 Hypersil BDS column (150 mm × 4.6 mm, 3.5 µm particle size) was used for chromatographic separation, offering effective peak shape …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 11–20 Read article
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Effects of Reels and short videos on human mind and Academic Life
Abstract: The rapid rise of short-form video platforms such as Instagram Reels, TikTok, and YouTube Shorts has fundamentally reshaped the way people consume information and entertainment. While these applications offer quick engagement and social connection, their excessive use has raised serious concerns about their psychological and academic impacts. This research investigates the relationship between short-form video addiction, mindfulness, academic anxiety, and academic engagement among university students. Drawing upon the theoretical framework …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 2, 2026 Read article
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Data-Driven Life Prediction of Fiber-Reinforced Polymer Composites Using IoT Sensing and Machine Learning Algorithms
Abstract: The accurate prediction of fatigue life in fiber-reinforced polymer (FRP) composites remains a major challenge due to their nonlinear, multi-mechanism degradation behavior under variable loading conditions. This study presents a data-driven framework, H-LiProNet, which combines real-time IoT sensing with hybrid machine learning to estimate remaining useful life (RUL) in FRP composites. The proposed system integrates embedded Fiber Bragg Grating (FBG) and acoustic emission (AE) sensors to capture strain and damage …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 116–130 Read article
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Development of a Novel Analytical Framework for Investigating Non-Symmetric Deformation Behavior in Strip Rolling
Abstract: In recent years, the asymmetrical rolling process has attracted considerable research attention due to its ability to induce non-uniform deformation characteristics within metallic workpieces. In this context, the present study introduces a novel analytical framework for asymmetrical cold rolling based on an enhanced slab method, specifically designed to overcome the inherent limitations of existing analytical models when applied to a wide range of asymmetric rolling conditions. A newly developed mathematical …
Published in Journal of Experimental & Applied Mechanics · Vol. 17, Issue 1, 2026 · pp. 1–21 Read article
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Optimization of Process Parameters for AISI 304 Using Micro-EDM Drilling Process Through Response Surface Method
Abstract: The increasing demand for micro-parts in high-tech products, such as micro-electromechanical systems (MEMS) applications and micro-electronic devices, has driven significant advancements in micromachining technologies. Among the various micromachining processes, the fabrication of accurate microholes and pins is critical for the performance and reliability of miniature components. Micro-hole drilling plays a vital role by enabling the production of deep holes with excellent straightness, roundness, and surface quality. It is widely used …
Published in International Journal of Manufacturing and Production Engineering · Vol. 3, Issue 1, 2025 · pp. 37–47 Read article
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Black Hole and Accretion Disks:Observational Discoveries and Theoretical Frameworks
Abstract: This review covers the essential elements of black hole accretion disk theory, beginning with the primary objective of understanding the complex nature of black holes. We delve into how key features of strong gravity, such as the event horizon, innermost stable circular orbit, and ergosphere, manifest in accretion disks. This review revisits the physical mechanisms driving accretion disks and presents four main models: thin disks, Shakura-Sunyaev disks, advection-dominated accretion flows …
Published in International Journal of Universe · Vol. 1, Issue 1, 2025 Read article
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Application of Priestia Megaterium in the Bioremediation of Petroleum Hydrocarbon Contaminated Environments
Abstract: Petroleum pollutants pose a serious and persistent threat to environmental ecosystems, particularly affecting soil and water quality. Effective and sustainable remediation strategies are crucial to mitigate their impact and safeguard environmental health. In this context, bioremediation—using microorganisms to degrade harmful contaminant —emerges as a promising and eco-friendly approach. The present study explores the biodegradation capabilities of the bacterium Priestia megaterium, a species previously recognized for its ability to break down …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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UV Method of Development and Validation of Olaparib
Abstract: An analytical method must be developed and validated in the discovery, development, and production of pharmaceuticals to ensure the identification, purity, potency, and performance of drug commodities. Quality control laboratories use official test protocols that emerge from the processes. A simple ultraviolet spectrophotometric approach was designed and validated using various characteristics, including linearity. Precision, reproducibility, accuracy, robustness, ruggedness, limit of detection, and limit of quantification are among the measuring criteria. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 20–27 Read article
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Revolutionizing Geopolymer Composites: Unveiling Intelligent Wall Facades and Precision PZT Sensors for Vibration Analysis
Abstract: Evaluating the mechanical performance and environmental benefits of geopolymer composites is imperative for sustainable alternatives in construction. This study presents an innovative circular PZT-based sensor that effectively captures transient vibrations within concrete structures, demonstrating its validity in comparison to standard surface-mounted accelerometers. The research also elucidates the influence of sensor orientation on capturing various vibrational modes of concrete. Furthermore, the embedded PZT sensors provide valuable insights into the evolving mechanical …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 59–73 Read article
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HPTLC Method Development and Validation for Rabeprazole Sodium in Pharmaceutical Formulation
Abstract: Background: The most common medication for acid related disorders stands as Proton pump inhibitor (PPI) Rabeprazole Sodium. The pharmaceutical formulations require essential quality control of Rabeprazole Sodium through reliable analytical methods to maintain reliability. HPTLC provides a cost-effective rapid method for drug quantification compared to conventional HPLC methods so how HPTLC stands as an appropriate method for drug determination. Objective: The emphasis of this research project involves developing and validating …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 18–24 Read article
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Numerical Simulation of Air Flow Field of A Gas Turbine Engine Air blast Atomizer
Abstract: One of the most crucial process that occurs before the fuel is burned in the combustion chamber is atomization. The performance of a engine will be depend mainly on the fuel mixture. Performance of the engine depends on atomization process because it breaks the bulk fuel into small droplets and injects it into the combustion chamber, in order to make this happen consequently the dimensions of most of the fuel …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 169–180 Read article
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Impact of Phosphorus Application Rates on Yield and Yield Components of Common Bean (Phaseolus vulgaris L.) Varieties in Relation to Water Resources at Yabello, Southern Oromia, Ethiopia
Abstract: Common bean is a key legume crop with significant economic importance in Ethiopia, particularly in the southern region of Oromia. One of the primary constraints to common bean productivity in this region is the issue of soil fertility, which is exacerbated by water scarcity. This study was conducted to assess the impact of phosphorus (P) fertilizer rates on common bean growth and yield, as well as to identify sustainable management …
Published in Journal of Water Resource Engineering and Management · Vol. 11, Issue 3, 2024 · pp. 20–31 Read article
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SoloRider: An Autonomous Self-Balancing Electric Bike for Sustainable Urban Mobility
Abstract: Rapid urbanization has intensified challenges such as traffic congestion, parking inefficiency, and environmental degradation. While autonomous vehicle research predominantly focuses on four-wheel platforms, lightweight two-wheelers remain comparatively underexplored. Two-wheelers are a great option for sustainable urban transportation because of their many benefits, including their small size, lower energy consumption, better manoeuvrability, and lesser infrastructure requirements. This paper presents SoloRider, a conceptual autonomous self- balancing electric two-wheeler de- signed for sustainable …
Published in International Journal of Electronics Automation · Vol. 4, Issue 1, 2026 Read article
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Real-Time Deepfake Detection in Video Conferencing Systems
Abstract: Deepfake technology presents non-exemplary threats to video conferencing platforms, enabling advanced fraud, impression and misinformation campaigns worth billions annually. Current detection methods either exhibit latencies exceeding 100ms or rely on server-side cloud processing, raising privacy concerns. This paper presents DeepConfGuard, a lightweight hybrid architecture combining MobileNetV2 for spatial feature extraction, a bidirectional LSTM with attention for temporal modelling, and EfficientNetV2 for refinement. It reaches 94.8% accuracy with 85 ms end‑to‑end …
Published in International Journal of Electronics Automation · Vol. 4, Issue 2, 2026 Read article
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A Community-Based Interventional Study on Knowledge, Attitude, and Practice on Usage and Management of Menstrual Products Among College Students
Abstract: Background and Aim: Menstruation is a fundamental physiological process affecting women’s health and well-being. Despite advancements, many women still face challenges in menstrual hygiene management due to lack of awareness, cultural taboos, and limited access to proper menstrual products and disposal methods. This study aimed to assess the knowledge, attitudes, and practices (KAP) regarding menstrual product usage and management among college students in Dakshina Kannada, India, and evaluate the impact …
Published in Trends in Drug Delivery · Vol. 11, Issue 3, 2024 · pp. 68–74 Read article
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Assessing the impact of E-business Technology on Supply Chain Management-in Context of Indian Industries
Abstract: E-business processes and internet technologies offer powerful competitive tools for higher revenues and profits in the industry. Creating an efficient supply chain network is crucial for providing affordable products with high quality, which is essential for gaining a competitive edge. Implementing e-business processes in the supply chain aims to improve overall performance by leveraging information technology advancements for easier coordination and reduced information costs. The research focuses on assessing the …
Published in International Journal of Manufacturing and Production Engineering · Vol. 2, Issue 1, 2024 · pp. 9–16 Read article
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Pain Management Through Ayurvedic Tablets and Capsules
Abstract: Triphala Guggulu is a classical formulation widely used in Ayurveda for the management of metabolic and inflammatory disorders. It represents a synergistic combination of Triphala – composed of Emblica officinalis, Terminalia bellirica, and Terminalia chebula – along with the oleo-gum resin of Commiphora mukul. In traditional Ayurvedic practice, this formulation has been prescribed for conditions, such as arthritis, obesity, hyperlipidemia, and chronic constipation, primarily due to its reputed ability to …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 1, 2026 · pp. 23–28 Read article
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Mechanical Characterization of Kevlar 49 and Pina Fiber Hybrid Composites
Abstract: The pursuit of sustainable yet high-performance materials has accelerated research into hybrid composites that combine synthetic and natural fibers. This study investigates the fabrication and characterization of a Kevlar 49/Pina fiber hybrid composite using epoxy resin as the matrix. Kevlar 49, known for its exceptional tensile strength and energy absorption, was employed as the face sheet material, while Pina fiber, a biodegradable reinforcement extracted from pineapple leaves, was incorporated as …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 301–316 Read article
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Effect of Initial Temperature and Diameter of Ethanol Droplet on Evaporation Dynamics in Convective Air Medium
Abstract: Ethanol is a suitable biofuel as it has fewer toxic emissions and higher-octane numbers. For spray combustion applications, the gas phase motion must be considered while numerically investigating the fundamental aspects of droplet evaporation and combustion processes. Hence, we have numerically simulated the evaporation dynamics of an isolated spherically shaped ethanol droplet under a forced convective air environment in the absence of gravity. The momentum transfer between two phases is …
Published in Journal of Polymer & Composites Read article
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Repurposing Approved Immunomodulatory Drugs for Target Proteins in the Pancreas of European eel: A Molecular Docking Approach
Abstract: Leishmaniasis is a disease caused by tiny parasites called Leishmania, which spread to humans through the bite of an infected female sand fly. The disease manifests in three different forms, and the protein calcitonin promotes the disease’s spread. By reducing blood calcium levels, inhibiting osteoclast activity, increasing calcium excretion, and possibly playing a role in neurotransmitter modulation, calcitonin, a hormone released by vertebrates, promotes the progression of pathogenesis and lessens …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 12–19 Read article