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243 articles for “Phytochemical activity.”
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Phenolic Compound Extraction from Leaves of Nyctanthesarbor-tristis
Abstract: Nyctanthes arbortristis is known as night-flowering jasmine and belongs to Oleaceae family. It is a fragrant white flowering shrub that is medicinally useful, sacred, and ornamental plant species. It is commonly grown in garden areas due to its pleasant fragrance and unique. The plant also growing on rocky areas in dry hillshades and is tolerant of moderate shade. It contains several phytochemicals like phenolic compound, flavonoids, tannins, alkaloids, saponins and …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 12, Issue 2, 2021 · pp. 72–76 Read article
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Punarnava (Boerhavia diffusa): A Promising Indigenous Herbal Drug and Its Effect on Different Disease Conditions
Abstract: Boerhavia diffusa is one of the famous medicinal plant uses to treat large number of human ailments as mentioned in Ayurveda. The plant in whole or its part have a numerous medicinal properties and are used by endemic and tribal people in India to show anti-bacterial, hepato-protective, hypo-glycemic, anti-proliferative, anti-estrogenic, anti-inflammatory, anti-convulsant, anti-stress and anti-metastatic activities and also in treatment of stress, dyspepsia, abdominal pain, inflammation, jaundice. Various phytochemical, pharmacological, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 4, Issue 2, 2015 · pp. 21–24 Read article
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Isolation, Characterization of Rhinacanthus Nasutus L. Kurz and Its Biological Evaluation
Abstract: The present paper deals with isolation, characterization and evaluation of anti-inflammatory, analgesic and anti-bacterial activities of n-hexane extract of Rhinacanthus nasutus L. Kurz. Extraction was carried out with soxhlet apparatus using solvents of increasing polarity. The anti-inflammatory activity was done by Carrageenan-Induced Paw Edema in rats. Analgesic activity was done by hot plate method and anti-bacterial activity by plate hole diffusion method. n-Hexane extract exhibited significant change in anti-inflammatory, analgesic …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 3, Issue 1, 2013 · pp. 9–15 Read article
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Targeting PTPN22 in Arthritis: Molecular Docking and Pharmacokinetic Evaluation of Artemisia vestita Compounds
Abstract: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by inflammation of the synovial membrane, commonly resulting in swelling, pain, stiffness, and overall fatigue. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been identified as a risk factor linked to various autoimmune diseases, including RA. In the PTPN22 gene, two missense Single nucleotide polymorphisms (SNPs) are associated with autoimmune conditions. The R620W (C1858T, rs247660) variant in exon 14 has been …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 20–31 Read article
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Therapeutic Potential of Cocculus hirsutus against COVID-19 Infection
Abstract: The complicated epidemiological situation of COVID-19 caused by continuous emergence of new variants with failure of eradication, monitoring and vaccination strategies opens the door to alternative solutions to save the current situation and prevent new disasters. One of the foremost promising alternatives is herbal products and botanicals. Herbal treatments are mainly dependent on the sign and symptoms of the patients. Cocculus Hirsutus is a rich source of phytochemical constituents which …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 12, Issue 1, 2022 · pp. 1–14 Read article
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Pylorus Ligation Induced Gastric Ulcer Protection by Sesamum Indicum Ethanolic Seed Extract
Abstract: The present study was performed in pylorus ligation induced ulcer model in Wister rats, in which ability to provide gastric protection was studied at two different doses 200 and 400 mg/kg calculated based on the acute toxicity study. Gastric protection was evaluated by assessing various parameters like gastric volume, pH, total acidity, free acidity, ulcer index and percentage inhibition of ulceration. Ranitidine at 50 mg/kg was used as the standard …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 3, 2015 · pp. 42–49 Read article
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Anti-Inflammatory Activity of Stem Bark of Homalium Zeylanicum Benth On Wistar Rats
Abstract: Due to the adverse effects of anti-inflammatory and anti-arthritic drugs, which are currently in clinical use, a need arises to develop newer anti-inflammatory and anti-arthritic agents with less side effects. The investigations of the efficacy of plant-based drugs used in the traditional medicine have evidenced great interest owing to their lesser side effects. In this context the present study was conceptualized to evaluate antioxidant and anti-inflammatory activity of Homalium zeylanicum …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 4, Issue 1, 2017 · pp. 39–50 Read article
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A Comprehensive Review on Biological Activities of Caesalpinia crista L. (Caesalpinaceae)
Abstract: Caesalpinia crista L., a member of the Caesalpinaceae family, is used for medicinal purposes. It's a thorny bush that grows in the tropics of India, Sri Lanka and the Andaman and Nicobar Islands, but can be found all over the world. It has a long history of importance as a therapeutic agent in the traditional plant system of India. This is a highly valued medicinal plant used in the ancient …
Published in Research & Reviews : Journal of Botany · Vol. 11, Issue 3, 2022 · pp. 12–26 Read article
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A Review on Ocimum Sanctum (Tulsi) and its Medicinal Properties
Abstract: Ocimum sanctum (Tulsi) is one of the most important plants mentioned in Ayurveda due to its religious values and enormous medicinal properties. It belongs to Lamiaceae family. Tulsi is an inexpensive, safe and easily available plant commonly found in all the Indian Hindu households. It is a sacred plant in Hindu belief and the offering of its leaves is mandatory in ritualistic worship. Plant parts like leaves, seeds and roots …
Published in Research & Reviews : Journal of Herbal Science · Vol. 10, Issue 3, 2021 · pp. 4–7 Read article
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Molecular Docking Studies of Nyctanthes arbor-tristis Phytochemicals for Targeting TNF Receptor in Arthritis
Abstract: Rheumatoid Arthritis is an autoimmune disorder which results in inflammation. Tumor necrosis factor-alpha (TNF-α) is responsible for the progression of inflammatory arthritis by promoting immune cell activation and cytokine release. The present study explores the potential of bioactive compounds derived from Nyctanthes arbor-tristis (Parijat) in modulating TNF receptor activity through molecular docking. Computational methods were employed to evaluate the binding affinity of selected phytocompounds from N. arbor-tristis against the extracellular …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 11–21 Read article
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Nutraceuticals as Adjunctive Treatment in Cancer Exploring Efficacy and Mechanism of Action
Abstract: Dietary habits are a critical factor in cancer prevention, with plant-based diets rich in vegetables and fruits associated with reduced cancer risk. Nutraceuticals—bioactive compounds derived from food and supplements—have gained attention for their potential in cancer prevention and therapy. Phytochemicals such as flavonoids, polyphenols, and alkaloids exhibit anti-cancer properties through mechanisms including antioxidant activity, anti-inflammatory effects, inhibition of tumor growth, and induction of apoptosis. Key nutraceuticals include alkaloids (e.g., caffeine, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 35–45 Read article
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Preparation, Phytochemical Screening and Pharmacological Evaluation of Poly-herbal Formulation
Abstract: AbstractThe current investigation was endeavored at formulating and evaluating a poly-herbal formulation. The poly-herbal formulation was a combination of 10 herbal ingredients which was phyto-chemically screened for the detection of various phyto-constituents. The formulation was subjected to in vitro Anti-Arthritic and Anthelmintic activity studies. Anti-Arthritic activity was evaluated using various concentrations of the formulation (100 μg/ml, 250 μg/ml, and 500 μg/ml) and Diclofenac sodium (100 μg/ml, 250 μg/ml, and 500 …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 10, Issue 2, 2020 · pp. 9–14 Read article
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A Review on Manihot Esculenta Species
Abstract: Manihot esculenta, which is commonly known as Cassava, is a woody shrub that provides a high source of carbohydrate. It is an annual crop native to tropical and subtropical regions of the world. Nigeria is the largest producer of the cassava plant. The parts of the plant like leaves, roots, stems, etc are consumed in a variety of ways as they have been shown to possess activities like analgesic, anti-inflammatory …
Published in Research & Reviews : Journal of Botany · Vol. 10, Issue 4, 2021 · pp. 6–10 Read article
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Green Synthesis of Selenium Nano-metalloid from the extract of Cabbage (Brassica oleracea var. capitata) leaf and its Antimicrobial Activities
Abstract: Green synthesis specifies the creation of nano-size particles (NPs) by a biological process using the reducing properties of metabolites in the plant extracts. The present work reports the use of cabbage (Brassica oleracea var. capitata.) leaf extract as a reducing and stabilizing agent to synthesize selenium nanoparticles (SeNPs) via the green route of synthesis. The as-prepared SeNPs were analyzed by UV–vis spectroscopy, FTIR, DLS, SEM, and EDX. Nano-crystalline SeNPs has …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 9, Issue 1, 2019 · pp. 12–20 Read article
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Review on Phytochemicals as Novel Therapeutic Strategies for the Treatment of Diabetes
Abstract: Diabetes is a worldwide concern. People are suffering from different variants of diabetes in the world, of which Type-1 and Type-2 diabetes are very common in the globe. In labor, gestational diabetes affects many ladies. Some other types of diabetes occur due to genetic changes and problems in pancreatic activity. Numerous Indians suffer from type-2 diabetes. Three diagnosis methods are employed for the detection of diabetes. The alteration in activity …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 9, Issue 2, 2022 · pp. 1–8 Read article
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Ant-deterrent Activity in Leaves of Cipadessabaccifera (Roth) Miq. and Aglaia roxburghiana (Wight & Arn.) Miq
Abstract: In view of the rich diversity of Indian medicinal plants, it is expected that screening and scientific evaluation of plant extract for their ant deterrent substance may prove beneficial for the mankind. As the Meliaceae members are not only ethnomedicinally important ones but also agriculturally important biopesticides, due to the presence of variety of bioactive compounds, several members have been phytochemically analyzed. The present work deals with ant-deterrent analysis of …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 7, Issue 1, 2017 · pp. 11–13 Read article
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Application of Fruit and Vegetables Peels as Functional Ingredients in Baked Cookies: A review
Abstract: About half of the waste produced by industrial fruit and vegetable manufacture is in the form of peels, cores, pomace, and unripe or damaged fruits and vegetables. Many fruits and vegetables, including citrus, apples, peaches, pears, bananas, pomegranates, berries, mangoes, and sugar beet, have peels, pulp/pomace, and seeds that contain concentrations of phenolics and other phytochemicals that are typically much higher than in the edible tissues of those fruits and …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 13, Issue 2, 2024 · pp. 11–19 Read article
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Exploring Potential Phytochemicals for Myasthenia Gravis Treatment: A Molecular Docking and ADME Analysis Approach
Abstract: Objective: Muscle feebleness and exhaustion derived from a disruption in neuromuscular transference are hallmarks of the crippling autoimmune disease myasthenia gravis (MG). The drawbacks of the current MG therapy options are frequently partial efficacy and adverse effects. To investigate the potential of phytochemicals in MG control, in this work we integrated molecular docking with ADME (absorption, distribution, metabolism, and excretion) analysis using a computer method. We identified molecules exhibiting favorable …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 1–13 Read article
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A Review on Seeds of Carica papaya
Abstract: Carica papaya is a nutritional fruit and belongs to Caricaceae family. It is in green and yellow color and highly content of antioxidants. Fresh seeds are stronger taste than dried seeds. Mainly these seeds contain a variety of micronutrients and good source of fiber. Copper, magnesium and potassium elements are very high. The seeds are improving our digestive health and protects the kidney function. It shows so many pharmacological properties …
Published in Research & Reviews : Journal of Botany · Vol. 9, Issue 2, 2020 · pp. 14–16 Read article
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Anticancer Activity of Calotropis procera by Molecular Docking Analysis
Abstract: Cyclin-dependent kinase 2 (CDK2) is a protein synthesized by Calotropis procera. It is known to be responsible for causing cancer in the human body. Studies have presented the significance of the phytochemicals to inhibit the CDK2 protein. Adsorption, distribution, metabolism, and excretion (Swiss ADME) and PubChem were the pharmacological tools which were used to check molecular weight, which should be less than 500D, acceptors less than 10, and donors less …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 01–07 Read article