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575 articles for “Novel methods”
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Design, Synthesis and Pharmacological Evaluation of Pyrazoline Substituted Benzimidazole Derivatives as Antibacterial and Antifungal Agents
Abstract: Background: Benzimidazoles are important heterocyclic compounds possessing a variety of biological activities such as anticancer, antioxidant, antiinflammatory, analgesic, anti-viral, anti-bacterial, anti-fungal and hypoglycemic activities. Pyrazolines are used as antitumor, immunosuppressive, antibacterial and anti tubercular agents. Aim : The present research focused on incorporating pyrazoline nucleus into benzimidazole nucleus to form a potent antibacterial and antifungal agent. Method: The in silico design of novel pyrazoline substituted benzimidazole derivatives was done using …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 3, 2020 · pp. 29–41 Read article
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Novel Probe Designs for the Scanning Kelvin Probe System
Abstract: The Scanning Kelvin Probe (SKP) Method is an indirect method to measure the electrochemical potential of a metal. Thus, in order to determine the potential of a given metal it is necessary to measure the Volta potential between it and an electrochemical reference electrode. Various designs of probes were developed to further improve the overall performance of the SKP system. Five novel probes were designed and tested with the SKP …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 1, Issue 1, 2014 · pp. 34–50 Read article
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A Cost-Effective Fast Cell Balancing Technique for Lithium- Ion Batteries using a Single DC–DC Converter with Direct Energy Transfer
Abstract: A novel quick lithium-ion battery balancing method with a single DC-DC converter for facilitating the direct energy transfer process in low and high voltage cells is introduced in this research work. Cost effectiveness in the design of the switch network is achieved by the use of relays in switching the cells. A control circuit including an MCU and a battery management IC is used for the sensing of cell voltages …
Published in Journal of Power Electronics and Power Systems · Vol. 16, Issue 2, 2026 · pp. 1–13 Read article
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Heuristic Application on Energy Storage System Allocation in Wind Integrated Power System
Abstract: Increasing penetration of renewable energy significantly alters the network power flow in terms of direction as well as magnitude. The intermittent and uncertain nature of renewable inputs is a major concern since the power flow in the system is affected considerably. Hence to support bulk integration of renewable energy in the power system, bulk or distributed energy storage systems can be implemented. The energy storage system is utilized to absorb …
Published in Journal of Power Electronics and Power Systems · Vol. 12, Issue 2, 2022 · pp. 21–31 Read article
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Anxiety Due to Predator Odour as a Novel Tool for Evaluating Anxiolytic Drugs
Abstract: Development of anxiolytic drugs is impaired due to the absence of a proper and reliable method. We have used the ethological aspects of animals such as intent to mate and food avoidance to research an anxiolytic drug called Aforte. Our findings have clearly shown that the ethological parameters are more reliable than the conventional pharmacological test such as elevated plus maze test, rota rod test, forced swim test. The ethological …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 1, 2019 · pp. 12–15 Read article
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A Novel Decomposable Pixel Component Analysis Algorithm for Automating Multispectral Satellite Image Denoising
Abstract: In comparison with the standard RGB or gray-scale images the usual multispectral images (MSI) is intended to convey high definition and an authentic representation for real world scenes to significantly enhance the performance measures of several other tasks involving with computer vision, segmentation of image, object extraction and object tagging operations. However, in practices a MSI image is always prone to corruption by various sources of noises while procuring the …
Published in Research & Reviews: A Journal of Embedded System & Applications · Vol. 2, Issue 3, 2014 · pp. 18–25 Read article
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A New Computational Method for Dust and Gas Dynamics in Protoplanetary Discs
Abstract: The simultaneous evolution of dust and gas in protoplanetary discs regulates essential events in planet formation, such as dust accumulation, migration, and the initiation of gravitational instabilities. Nevertheless, precisely modelling this interaction continues to provide a significant computing problem owing to the extensive variety of spatial and temporal scales involved. In this study, we introduce an innovative computational framework for simulating dust-gas dynamics in protoplanetary discs, integrating a two-fluid hydrodynamical …
Published in International Journal of Universe · Vol. 1, Issue 2, 2025 · pp. 35–46 Read article
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Integrating Network Pharmacology and Molecular Docking to Investigate Boerhavia diffusa for Pancreatic Cancer Treatment
Abstract: Objective: In this study, network pharmacology was applied to determine the therapeutic effects of the bioactive compounds of Boerhavia diffusa. Network pharmacology can unearth the underlying mechanisms between drugs and the disease targets and aids in the discovery of novel medications for complex conditions such as cancer. Methods: To predict the molecular mechanisms of action of Boerhavia diffusa in the treatment of was screened using the GeneCards database. The Venn …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 29–49 Read article
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Direct Synthetic Routes of MXenes and Their Application in Carbon Fiber Reinforced Plastics (CFRPs) As Supplementary Sizing Layer†
Abstract: Sized carbon fibers with a supplementary sizing layer of MXenes (synthesized via traditional MAX phases), bonded to carbon fibers (CFs) as well as the resin matrix via different kinds of physicochemical (van der Waals force, hydrogen bonding, covalent bonding) interactions enhanced the performance of the resulting carbon fiber reinforced plastic (CFRP) materials. This is because of the strong interface generated due to the appearance of MXene at the interface of …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 1, 2024 · pp. 07–13 Read article
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Microwave-Assisted Synthesis of Li₃Ba₂Gd₃(MoO₄)₈ Phosphors Doped with Pr³⁺ and Sm³⁺ for High-Performance Red Emission in LED Applications
Abstract: In this study, we report the successful synthesis of Li₃Ba₂Gd₃(MoO₄)₈ (RE³⁺ = Pr³⁺, Sm³⁺) phosphors using a novel, microwave-assisted solid-state reaction method at ambient temperature. The synthesis involved the use of analytical grade reagents including Lithium Nitrate (LiNO₃), Barium Nitrate, Gadolinium Nitrate (Gd(NO₃)₃·6H₂O), Ammonium Molybdate ((NH₄)₆Mo₇O₂₄·24H₂O), and high-purity oxides of Praseodymium (Pr₂O₃) and Samarium (Sm₂O₃). The reagents were mixed in stoichiometric ratios, ground thoroughly in a pestle and mortar, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 18–32 Read article
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Looking into new ideas in green chemistry
Abstract: Green chemistry has become a revolutionary way to change chemical processes such that they have less of an effect on the environment while still being efficient and cost-effective. This article looks at new developments in green chemistry that go beyond small changes and offer completely new ways to build chemicals that are good for the environment. There is a lot of focus on innovative catalytic systems, sustainable feedstocks, reaction pathways …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 1, 2026 · pp. 10–18 Read article
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Drug Discovery and Design: Focus on computational approaches used in the discovery and design of new drugs
Abstract: Computational approaches have revolutionized the field of drug discovery and design, offering efficient and cost-effective strategies for identifying and developing new therapeutics. This review article explores the application of computational methods in drug discovery, with a focus on virtual screening techniques, molecular docking, molecular dynamics simulations, and quantitative structure-activity relationship (QSAR) models. Virtual screening plays a crucial role in narrowing down large chemical libraries by utilizing ligand-based and structure-based approaches. …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 1, 2023 · pp. 26–30 Read article
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Enhancing Secure Communication Through Hybrid Steganography and Public Key Cryptography
Abstract: This research pioneers an innovative paradigm in secure data communication by seamlessly merging Public Key Digital Image Steganography with public key cryptography. The proposed method leverages the formidable strength of the RSA algorithm, employing a robust 1024-bit key size for secure data encryption. In parallel, the imperceptibility of the F5 steganographic technique is harnessed to clandestinely embed the encrypted message within a cover image. Unlike conventional methods, our scheme introduces …
Published in Journal of Mobile Computing, Communications & Mobile Networks · Vol. 10, Issue 3, 2023 · pp. 38–46 Read article
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In- silico Design of Novel Inhibitors for 5-HT2A Receptor to Recuperate Schizophrenia
Abstract: Schizophrenia is a mental disorder characterized by positive symptoms such as disorganized speech, delusions and hallucinations and negative symptoms such as deficits of attention, affective flattening and social withdrawal in nature. There are several receptor involve in schizophrenia, one of these 5-HT2A receptor i.e. serotonin receptor. The serotonin receptor 5-HT2A has been involved in several neurological conditions and potent 5-HT2A inhibitors have therapeutic effects that use for the treatment of …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 2, Issue 2, 2015 · pp. 11–17 Read article
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A Novel Technique for Stability Testing of Alliin and Sennosides in Unani Formulations
Abstract: Unani system of medicines is a science which deals with the preventive and promotive aspects of health of human beings and health problems that arise due to factors like ecological and/or environmental, which include humours categorized as blood, phlegm, yellow bile and black bile, and different biological fluids circulating in various vessels of the body. There is significant mandate in drug testing for a specific and precise analytical method for …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 1, Issue 1, 2014 · pp. 1–5 Read article
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A Common Mode Scan Based BIST for Stuck-at-Fault and Path Delay Fault
Abstract: Testing for delay and stuck-at faults requires two pattern tests and test sets are usually large. Built-in self-test (BIST) scheme is attractive for comprehensive testing. The BIST test pattern generators (TPGs) for such testing should be designed to ensure high pattern-pair coverage. In the proposed work, necessary and sufficient conditions to ensure complete/maximal pattern-pair coverage for sequential circuit have been derived. A new test data-compression scheme is an effective approach …
Published in Journal of VLSI Design Tools and Technology · Vol. 8, Issue 2, 2018 · pp. 72–78 Read article
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Modulation of Receptor Proteins: A Recent Paradigm in Drug Discovery and Target
Abstract: The main aim in drug discovery is to design different ligands those work on specific drug targets. However, various effective drugs work through the modulation of many proteins than single target. Advancement in system biology are establishing a phenotypic strength and a network structure, which suggests that, the excellent selective compounds may be performed less than desired clinical efficacy in comparison to multi-target drugs. In this new appreciation of the …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 1, 2018 · pp. 14–24 Read article
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Synthesis of Iron Oxide Nanoparticle by Self Assembly Method and Catalytic Application
Abstract: Normal 0 false false false EN-US X-NONE X-NONE Iron oxide nanoparticle is a kind of novel functional material, which has been used in biotechnology and catalysis. In this study, the iron oxide nanoparticle was synthesized by self-assembly method and characterized by XRD, FT-IR, SEM and AFM analyses. The synthesized iron oxide nanoparticles were used for the catalytic degradation of a synthetic dye, Direct Red 7 (DR7). Iron oxide nanoparticles with …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 2, Issue 1, 2011 · pp. 16–23 Read article
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Vacant Parking Lot Detection
Abstract: AbstractAn issue looked in significant metropolitan regions, is the scan for parking spot. This study proposes a novel path for programmed parking garages’ location. In this methodology, first separate highlights by creating location patches and building Gaussian ground model from info video outlines. At that point, this model is utilized to prepare an eight-class multi-SVM classier. At last, the classification is upgraded internationally by means of Markov Random Field. This …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 6, Issue 2, 2019 · pp. 11–21 Read article
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Evaluation of Solar Heat Gains and Environmental Influence of the Phase Change Material (PCM) Wall
Abstract: Solar powered warm vitality can be viably put away in dividers of a working by joining stage change materials (PCMs) inside them. Plasterboards containing PCM can be utilized to assimilate and store solar based warmth picked up amid daytime and discharge or put away warmth amid evening time. A divider fitted with plasterboards containing PCM is typically called a PCM divider. In this review, south façade of a test room …
Published in Journal of Thermal Engineering and Applications · Vol. 4, Issue 2, 2017 · pp. 8–17 Read article