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152 articles for “Drug utilization”
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Characterization of Cellulose Producing Bacterial Isolates from Rotten Fruits
Abstract: Cellulose, the most abundant natural polymer, is predominantly sourced from plant wood but can also be synthesized by certain bacteria in the form of bio-cellulose. The potential applications of bio-cellulose are extensive, particularly in the biomedical field for tissue engineering, drug delivery, and more. The distinct properties and purity of bacterial cellulose, in contrast to plant-derived cellulose, underscore its importance and drive further research in the area. This study focuses …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 38–45 Read article
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Literature Review On Nanotechnology In Dentistry
Abstract: Nanotechnology is a relatively new field in dentistry that utilizes nanomaterials, nanorobots, and nanotechnology for diagnosing, treating, and preventing dental diseases. Nanotechnology has revolutionized various fields of dentistry, offering innovative solutions that enhance patient care, improve treatment outcomes, and contribute to the overall advancement of dental science. This cutting-edge technology has found applications in several areas, including restorative dentistry, dental implants, early cancer diagnosis, dental hypersensitivity, and pain management, among …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 2, 2025 · pp. 19–23 Read article
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Role of W.A.R. Score in Predicting Wound Infection
Abstract: In clinical practice, chronic wounds are a major difficulty that are frequently made worse by the infection risk. However, the lack of precise standards for evaluating the risk of infection and establishing the need for and length of time for systemic antibiotics leads to the overuse and abuse of these drugs, which increases the risk of side effects and the development of antibiotic resistance. To close this gap, the development …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 33–38 Read article
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A Research on the Additives and Regulatory Requirements for Pediatric Formulation
Abstract: These days, pediatric considerations are incorporated early on in the creation of new medications. The guidelines and policies of European drug regulatory bodies served as the foundation for our investigation. The review comprehensively outlines excipients commonly found in pediatric medicine formulations. It identifies potentially harmful compounds flagged by scientific literature, stressing the necessity of rigorous safety checks, often involving toxicity studies. Excipients included in pediatric databases, like the STEP database, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 28–45 Read article
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Harnessing Nature: Formulations for Colon Cancer Prevention and Treatment
Abstract: Colon cancer, a rapidly advancing disease worldwide, involves the carcinogenesis of the distal part of the intestine. This malignancy progresses through various developmental stages necessitating diverse treatment approaches. Traditional treatments include drug therapy and chemotherapy; however, emerging methods, such as the use of phytochemical compounds offer promising mechanisms for combating this disease. Phytochemical compounds derived from natural food sources, including flavonoids, tannins, resveratrol, and epigallocatechin-3-gallate, exhibit potent anti-cancer properties. They …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 3, 2024 · pp. 11–23 Read article
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UV Method of Development and Validation of Olaparib
Abstract: An analytical method must be developed and validated in the discovery, development, and production of pharmaceuticals to ensure the identification, purity, potency, and performance of drug commodities. Quality control laboratories use official test protocols that emerge from the processes. A simple ultraviolet spectrophotometric approach was designed and validated using various characteristics, including linearity. Precision, reproducibility, accuracy, robustness, ruggedness, limit of detection, and limit of quantification are among the measuring criteria. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 20–27 Read article
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A Systematic Review of Method Development and Validation for Ramipril Analysis Using Hplc in Cardiovascular Research
Abstract: The field of analytical chemistry encompasses a variety of methods that are crucial in determining the chemical composition of different substances. UV-visible spectroscopy and high-performance liquid chromatography (HPLC) are two widely utilized methods that are the subject of this article. UV-visible spectroscopy uses the Beer-Lambert law to quantify light absorption, which can provide information about the concentration of absorbing species. The method is based on how light and matter interact, …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 2, 2024 · pp. 37–44 Read article
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Molecular Pharmacokinetics and Structural Docking of Phenolic Acids for Targeting NF-κB Pathway Components in Inflammation and Fibrosis: A Computational Approach Toward Therapeutic Discovery
Abstract: Inflammation and Fibrosis are critical pathological processes associated with various chronic diseases, often mediated by the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway. This study investigates the therapeutic potential of phenolic acids as modulators of the NF-κB pathway, aiming to identify novel ligands that can effectively interact with key components of this signaling cascade. A comprehensive computational approach was employed, utilizing molecular docking, pharmacological screening, and post-docking …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 14–31 Read article
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The Therapeutic and Biotechnological Potential of : Pogostemon benghalenesis, A Comprehensive Review
Abstract: Pogostemon benghalensis is a fragrant perennial shrub belonging to the family Lamiaceae, widely distributed across tropical and subtropical regions of Asia. It has been extensively utilized in traditional and ethnomedicinal systems for the treatment of wounds, skin infections, fever, digestive disorders, inflammation, and respiratory ailments. The plant is also valued for its antiseptic, aphrodisiac, insect-repellent, and veterinary medicinal properties. Its leaves, roots, and essential oil are incorporated into herbal formulations, …
Published in Research & Reviews : Journal of Botany · Vol. 15, Issue 2, 2026 Read article
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QSAR Modeling of a Novel Series of Methoxylated Chalcones as Antioxidant Agents Against Gram-Positive Bacteria Staphylococcus aureus
Abstract: Background: Chalcones are aromatic ketones belonging to the flavonoid family. They are plant-based compounds and are widely found in nature. For centuries, these bioactive molecules have been utilized in various traditional medicines for the treatment of several ailments. Chalcones have antibacterial, antiviral, antimalarial, antifungal, antioxidant, and antileishmanial properties. They are also used to treat inflammation and cancer. Chalcones act as angiogenesis inhibitors, an important factor in cancer progression and metastasis. …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 28–34 Read article
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The Burden of Empirical Therapy: Analyzing the Predominance of Broad-Spectrum Antibiotic Usage in Lower Respiratory Tract Infections
Abstract: Lower respiratory tract infections (LRTIs) remain one of the leading causes of morbidity and hospitalization worldwide, particularly among older adults, immunocompromised individuals, and patients with chronic respiratory disorders. These infections include conditions such as community-acquired pneumonia, hospital-acquired pneumonia, bronchitis, and acute infective exacerbations of chronic lung disease, all of which often require rapid clinical intervention. Because microbiological confirmation of the causative pathogen frequently takes 48–72 hours, clinicians generally initiate empirical …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article
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Comparative Efficacy and Safety of Safinamide and Rasagiline in the Treatment of Parkinson’s Disease: A Meta-Analysis and Systematic Review
Abstract: Background: Recent studies have suggested Rasagiline and Safinamide monotherapy as potential management options for Parkinson’s disease. Parkinson’s disease, a neurological disorder characterized by tremors and movement difficulties, necessitates treatments aimed at managing clinical symptoms. Levodopa remains the primary effective treatment for Parkinson’s disease symptoms; however, its long-term use often leads to motor complications in many patients. Additional therapeutic drugs, such as dopamine agonists and monoamine oxidase B inhibitors, including Safinamide …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 74–91 Read article