Search
237 articles for “hype”
-
Overview of Virulence Factor of Staphylococcus sp.
Abstract: Staphylococcus is a highly virulent genus of bacteria that can cause a range of infections in humans and animals. The production of toxins, enzymes, and biofilms contributes to its ability to establish infections and evade host defenses. Understanding the characteristics and virulence factors of Staphylococcus is crucial for the development of effective prevention strategies and treatment options. Staphylococcus aureus is a significant etiological agent of nosocomial infections on a global …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 1, 2024 · pp. 25–31 Read article
-
Molecular Docking studies of Benzodiazepine Derivatives With GABA(B) Receptor
Abstract: Benzodiazepines (BZDs) are pharmacologically significant compounds that act by binding to GABA A neurotransmitter receptors, subsequently augmenting GABA-induced chloride ion flux, consequently inducing neuronal hyperpolarization. Benzodiazepines are commonly used in the treatment of sleep disorders, anxiety, muscle spasms, seizure disorders, and some forms of depression. The primary inhibitory neurotransmitter, GABA, functions on two types of receptors: the ligand-gated GABA A/C receptors and the G protein-coupled GABA B receptors. These neurotransmitters …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 1–14 Read article
-
Innovative Use of Pressure Relieving Foam Based Garment for Lumbar Pressure Sore
Abstract: Pressure ulcers, stemming mainly from friction and shear forces, manifest as chronic wounds that worsen over time. They commonly afflict individuals who are bedridden or have limited mobility. Our investigation involved a 62-year-old male with a hypertrophic scar on his back resulting from the excision of a carbuncle. Subsequently, he developed a lumbar pressure sore at the scar site. To address this issue, adjustments were made to his pressure garment, …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 52–56 Read article
-
Breaking Barriers: How Telemedicine is Reshaping Access and Quality in Healthcare
Abstract: Thanks to advancements in telecommunications technology, telemedicine has become a disruptive force in the delivery of healthcare, bridging geographical and accessibility gaps. This article offers a thorough examination of the advantages, difficulties, and potential applications of telemedicine in healthcare. Telemedicine has a number of benefits, one of which is that it makes healthcare more accessible, especially for underprivileged groups living in rural or isolated places. Telemedicine makes it possible for …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 1–4 Read article
-
Predictive Modeling and Optimization of Tensile and Flexural Strength in FDM 3D Printing Using Decision Trees and Bayesian Optimization.
Abstract: This research investigates predictive modelling and optimization technique for the tensile and flexural strength of PlA (Poly Lactic Acid) in Fused Deposition Modelling (FDM) 3D printing. Employing Decision Trees and Bayesian Optimization enhances comprehension and control of 3D printing process. Precise model predicts PLA material properties based on input parameters. Methodology involves rigorous data preprocessing, encompassing, cleaning, transformation, and normalization. Hyperparameter optimization via grid search systematically explores configurations, optimizing model …
Published in Journal of Polymer & Composites · Vol. 11, Issue 12, 2023 · pp. 203–214 Read article
-
Classifying Abnormalities in Heartbeat Sound
Abstract: Heartbeat sounds play a major role in the detection of various diseases such as heart disease, hyperthyroidism, and high blood pressure in their early stages. In the proposed method, various abnormal and healthy heartbeat audio signals are given as input and the features are extracted using MFCC (mel-frequency cepstral coefficients). Then, a deep learning approach is applied in which the MFCC audio signals are sent to the CNN (convolutional neural …
Published in Research & Reviews: A Journal of Embedded System & Applications · Vol. 12, Issue 1, 2024 · pp. 24–31 Read article
-
Evolution of War Technology
Abstract: The continued evolution of combat technology is examined in this research study, which also discusses recent trends, historical developments, and possible future developments in this important area. Throughout history, the quest for military superiority has propelled considerable advancements in warfare technology. This study provides a succinct examination of this evolutionary process, shedding light on historical turning points, modern cutting-edge technologies, and expected future developments in combat. Important advances in the …
Published in Journal of Advancements in Robotics · Vol. 11, Issue 1, 2024 · pp. 25–32 Read article
-
Formulation and Analyzation of Murraya Koenigii Herbal Antimicrobial Cream
Abstract: A person's skin is a crucial indicator of their overall health. Everyone experiences skin issues from time to time in their lives. Wrinkles, acne, pimples, dark spots, hypersensitivity, and atopic dermatitis are some of the ways they might manifest. The aim of this project was to formulate the herbal cream for the purpose of the moisturising, cooling, cure inflammation, itching, skin eruptions, persistent boils, wound healing, antimicrobial, and treatment of …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 8–14 Read article
-
Simultaneous Determination And Stability Indicating Method For Telmisartan, Metoprolol Succinate And Cilnidipine In Tablet Dosage Form.
Abstract: There are several medicinal agents available for antihypertensive activity. Telmisartan, metoprolol and cilnidipine are among them. Quantitative and qualitative analysis plays a pivotal role in safeguarding patients. Here, the estimation of these drugs was performed by using the chromatographic technique RP-HPLC. It was conducted with Phosphate buffer (pH 3.5 ± 0.01): Methanol (50:50 v/v) mobile phase. The system was operated at 1 ml/min. Drug volume to the system was 20μl. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 32–38 Read article
-
Interplay of Thyroid Dynamics in Type 2 Diabetes: A Comprehensive Analytical Study at Government Medical College, Kota, and Affiliated Hospitals
Abstract: Diabetes mellitus is a prevalent endocrine metabolic condition that causes significant morbidity and mortality globally. Innumerable metabolic processes within our bodies depend on thyroid hormones. Excess or deficiency in insulin or thyroid hormones might cause functional problems. The intricate relationship between thyroid disorders and diabetes has been recognized for a considerable period. Patients with diabetes have been known to experience thyroid malfunction, the most prevalent kind of which is hypothyroidism. …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 6–11 Read article
-
In Silico Investigation of 2,3-Dihydrobenzofuran from Centella asiatica: A Possible Pioneer in the Management of Tetanus
Abstract: Objective: Tetanus toxin (TeNT) is a neuroprotein toxin, the most toxic known. They have three functional domains and are structurally similar. They possess an N-terminal catalytic section (light chain), an internal domain for heavy-chain translocation (HN domain), and a C-terminal receptor binding domain for the heavy chain (Hc domain or RBD). Tetanus, an acute nerve-affecting disease, is provoked by a toxin-producing bacterium called Clostridium tetani. This bacterium is environmental, Gram-positive, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 19–30 Read article
-
Global Burden of Major Depressive Disorder: Prevalence, Diagnosis, and Impact: A Comprehensive review
Abstract: In this review, we will discuss about the major depressive disorders on the basis of neurobiological changes. MDD, a prevalent psychiatric condition, manifests as a complex interplay of genetic, environmental, and physiological factors with a substantial impact on individuals and societies globally. Here the clinical assessment is fully based on diagnosis and the statistical manual for mental disorder, 5th edition (DSM-5). The pathophysiology involves Diagnosis alterations in neurotransmitter systems, dysregulation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 54–62 Read article
-
Role of Gastric Receptors in Gastrointestinal Disorder
Abstract: The established and potential roles of cholecystokinin1 and cholecystokinin2 receptors in gastrointestinal and metabolic diseases are analyzed, along with findings from human studies involving agonists and antagonists. While there is considerable evidence implicating cholecystokinin1R in various diseases such as pancreatic disorders, motility disorders, tumor growth, satiety regulation, and cholecystokinin-deficient states, its specific role in these conditions remains ambiguous. Conversely, the role of cholecystokinin2R in physiological (e.g., atrophic gastritis) and pathological …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 37–49 Read article
-
Therapeutic Potential of Composite Flour Prepared from EleusineCoracana and Cicer Arietinum
Abstract: Composite flour is a mixture of wheat and non - wheat flours used for the preparation of bakery products such as, breads, tarts, muffins, biscuits etc that is rich in protein and starch. Finger millet is considered as a special food supplement because of its unique nutritional properties when compared with other cereals. It is also known as poor man’s food. Many dishes, both in their natural and malted forms, …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 13, Issue 1, 2024 · pp. 31–41 Read article
-
Novel Nanotherapeutics for the Management of Diabetes
Abstract: Diabetes is a severe chronic disorder with hyperglycemia, either due to dysfunctional pancreas(Type I) or due to malfunctioned glucose utilizing entities like: liver, straight muscle or adipocytes (Type II). Type 1 or Insulin-dependent/Juvenile diabetes and Type 2 Diabetes Mellitus or Non-Insulin dependent/Adult-onset diabetes are the two broad classifications of diabetes. In case of type 1 diabetes injectable insulin is the major form of medication given and in case of Type …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 1, 2024 · pp. 46–67 Read article
-
Theoretical Study of Surface Waves in Hexagonal Boron Nitride (hBN)
Abstract: Hexagonal boron nitride (hBN) is a wide bandgap semiconductor material in which Boron (B) and Nitrogen (N) atoms form hexagonal structure and has number of robust properties of technological importance. Boron nitride nanotubes (BNNTs) are very nice area of research in recent years. Its structure is similar to carbon nanotubes (CNTs) where carbon atoms are arranged in hexagon. hBN is also known as White Graphene. Various methods are employed to …
Published in Research & Reviews : Journal of Physics · Vol. 13, Issue 1, 2024 Read article
-
Health Implications of Electromagnetic Wave Exposure
Abstract: From low-frequency radio waves to high-frequency gamma rays, electromagnetic waves have a wide range of effects on human health. This diverse subject includes an extensive spectrum of waves. The non-thermal effects of low-frequency waves, such as microwaves, are not completely understood despite the fact that they predominantly represent thermal dangers, which could potentially lead to tissue heating and damage similar to those caused by heating. High-frequency radiation, such as gamma …
Published in Research & Reviews : Journal of Physics · Vol. 13, Issue 1, 2024 · pp. 9–13 Read article
-
Harnessing Microbial and Phytoremediation Techniques for Sustainable Remediation of Heavy Metals in Black Cotton Soils
Abstract: Black cotton soils, renowned for their fertility and moisture retention capabilities, face significant challenges due to heavy metal contamination, posing threats to both agricultural productivity and environmental integrity. This review paper presents a comprehensive overview of bioremediation strategies aimed at mitigating heavy metal pollution in black cotton soils. The paper underscores the importance of addressing heavy metal (HM) contamination, emphasizing the need for exploring bioremediation techniques, as it sets the …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 193–201 Read article
-
A Web Application for Predicting Diabetes Using Machine Learning Methods
Abstract: Diabetes is a long-term disease caused by high glucose quantity in the blood. It has the potential to result in serious health complications like heart disease, hypertension, and ocular damage. It is good to identify any health issues as early as possible to get the right medical treatment and make necessary lifestyle adjustments. One makes use of machine learning techniques to predict diabetes and develop treatment options using actual cases. …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 11, Issue 3, 2024 · pp. 92–102 Read article
-
Host Interface of Cystic Fibrosis and P. aeruginosa
Abstract: A clash between microbial infection and host immunity can contribute to multiple diseases. Cystic fibrosis is one of those diseases. It’s an autoimmune disorder and hyperinflammatory disease, caused by pseudomonas aeruginosa, it’s the most predominant pathogen causing this disease. The progression of the lung infection cystic fibrosis is driven by host pathogen interface that focuses on the host and the bacterial factors. The disease has an interplay between the host, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 3, 2024 · pp. 9–31 Read article