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135 articles for “genetic improvement”
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Role of Crispr-Cas9 in Plants
Abstract: The innovative CRISPR Cas9 system has emerged as a game changing genetic engineering tool in years offering levels of precision, efficiency and flexibility in editing the genomes of various organisms, including plants. This summary aims to provide an examination of the role of CRISPR Cas9, in modifying plant genomes highlighting its benefits, drawbacks and possible uses. Thanks to its versatility and user-friendly nature CRISPR Cas9 technology has expedited studies in …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 3, 2024 · pp. 1–10 Read article
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A Comprehensive Review On Panic Disorders
Abstract: Panic disorder is a prevalent mental health condition characterized by sudden, recurring episodes of intense fear accompanied by physical symptoms. It is twice as likely to affect women and may have a genetic predisposition. This disorder stems from an exaggerated response of the body's survival mechanisms and hormones, impacting manifestations like agoraphobia. Additionally, it is associated with significant psychiatric comorbidity and impaired functioning in various roles. Recent research has delved …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 1, 2024 · pp. 53–59 Read article
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Factors Affecting Coffee Market Supply of Smallholder Farm Household: The Case of Gimbo District Kaffa Zone, Southwest Ethiopia.
Abstract: Abstract This study analyzes the factors influencing the market supply of coffee in selected districts of Gimbo District, Kaffa Zone, and Southwest Ethiopia. Coffee is Ethiopia’s most significant export crop, contributing substantially to the country’s GDP and exhibiting broad genetic diversity. Despite the high production potential of the district, the marketing system remains predominantly conventional, forcing producers to sell through traditional transaction routes that do not offer premium prices, thereby …
Published in Research & Reviews : Journal of Agricultural Science and Technology Read article
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AI-Accelerated Development of Gradient Polymer Nanocomposite Thin Films
Abstract: Gradient polymer nanocomposite thin films are an active field of materials research due to the fact that it enables scientists to de-facto regulate the optical, electrical, and mechanical properties of a film by merely altering its composition on a layer-by-layer basis. This type of control opens the gate to the improved flexible electronics, long lasting protective coats, and the new smart gadgets. The problem is, though, that it is a …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 456–469 Read article
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An Evaluative Comparison of CD123 and CD66c as Biomarkers to Detect Minimal Residual Disease in B-Cell Acute Lymphoblastic Leukemia
Abstract: Background: B-cell Acute Lymphoblastic Leukemia (B-ALL) often shows lineage heterogeneity with lymphoid cells expressing myeloid markers. Minimal Residual Disease (MRD) refers to the small number of cancer cells that may remain in a patient's body after treatment and that are undetectable by standard diagnostic methods. In diseases like B-cell Acute Lymphoblastic Leukemia (B-ALL), MRD is a critical prognostic indicator, as its presence can signal a higher risk of relapse. In …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 7–12 Read article
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Drug-Induced Liver Injury: Hepatotoxicity and Treatment - A Literature Review
Abstract: Drug-induced liver injury (DILI) is a major clinical and regulatory challenge, posing risks to patient safety and drug development worldwide. As the primary organ responsible for xenobiotic metabolism, the liver is particularly susceptible to toxic injury from prescription drugs, over-the-counter medications, herbal products, and dietary supplements. Drug-induced liver injury (DILI) accounts for a substantial proportion of acute liver failure cases and remains a leading cause of post-marketing drug withdrawal. Its …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 1, 2026 · pp. 1–17 Read article
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Milk Allergy: Significance, Detection and Management
Abstract: Milk allergy is a significant public health issue, particularly among infants and young children, with prevalence rates between 2 and 6% in early childhood, declining to 0.1–0.5% in adulthood. It is an immune-mediated adverse reaction to milk proteins, primarily involving immunoglobulin E (IgE)-mediated responses. Symptoms range from gastrointestinal distress and respiratory complications to severe anaphylaxis. The etiology of milk allergy involves genetic predisposition, environmental factors, an immature immune system, and …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 14, Issue 1, 2025 · pp. 15–19 Read article
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Determinants of Smallholder Farmers Quantity of Coffea arabica L., Supply to Market: A Case of Gimbo District, Kaffa Zone, Ethiopia
Abstract: This study investigates the factors influencing the market supply of coffee in various districts of the Gimbo District, Kaffa Zone, in Southwest Ethiopia. Coffee is Ethiopia's most significant export crop, recognized for its extensive genetic diversity and its substantial contribution to the country's GDP. Despite the district's strong production capacity, the marketing structure remains predominantly traditional, compelling producers to sell through conventional channels that do not offer premium prices, thereby …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 14, Issue 3, 2025 · pp. 107–120 Read article
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Global Burden of Major Depressive Disorder: Prevalence, Diagnosis, and Impact: A Comprehensive review
Abstract: In this review, we will discuss about the major depressive disorders on the basis of neurobiological changes. MDD, a prevalent psychiatric condition, manifests as a complex interplay of genetic, environmental, and physiological factors with a substantial impact on individuals and societies globally. Here the clinical assessment is fully based on diagnosis and the statistical manual for mental disorder, 5th edition (DSM-5). The pathophysiology involves Diagnosis alterations in neurotransmitter systems, dysregulation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 54–62 Read article
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Tools, Modern Drugs, and Latest Investigations for the Diagnosis and Treatment of Heart Failure: A Systematic Review of the General Causes
Abstract: Heart failure (HF) diagnosis and treatment present formidable challenges, given the absence of a definitive single test. This systematic literature review aims to comprehensively analyze the current landscape of diagnostic tools, modern drugs, and latest investigative approaches in HF management. Recognizing the complexity of HF etiology, this systematic review emphasizes the importance of advanced diagnostic methods, such as genetic testing and artificial intelligence applications. The systematic review was conducted to …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 1–10 Read article
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Skin Cancer Detection System Based on Machine Learning for Recognition of Cancerous Images
Abstract: Skin cancer ranks among the most prevalent types of cancer globally and poses significant risks when left untreated. Skin cancer arises when abnormal cells proliferate uncontrollably in the skin. This uncontrolled growth can be triggered by genetic mutations, exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds, or various other factors. In this, the early detection of cancer plays a crucial role in treatment and …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 2, 2024 · pp. 1–8 Read article
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Evolution and Impact of Forensic DNA Typing in Modern Investigation
Abstract: Forensic DNA typing is sometimes called DNA fingerprinting. Immigration, paternity, and criminal investigations use forensic DNA typing. Forensic genetics today includes bodily fluid identification, fast DNA analysis, forensic microbiology, and phenotypic profiling. Human cells contain DNA, a molecular code. Human DNA sequences are 99.9% the same in everyone. Every person has almost 0.1% unique DNA. Forensic experts also worry about this 0.1 percent of DNA that is unique. There are …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 62–66 Read article
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Managing Carpal Tunnel Syndrome: Insights into Symptoms and Relief
Abstract: Carpal tunnel syndrome (CTS) is a prevalent and concerning issue affecting the wrist and hand, arising from the compression of the median nerve within the carpal tunnel. This compression results in a spectrum of distressing symptoms, including numbness, tingling, weakness, and discomfort, particularly in the thumb, index, and middle fingers. Despite its frequent association with repetitive hand movements and prolonged use of computers or handheld devices, CTS can stem from …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 6–12 Read article
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A Comprehensive Review on Male Infertility
Abstract: The failure to attain a clinical pregnancy naturally after one year of unprotected intercourse is termed as infertility. Some of the factors that contribute to Infertility are late marriages, advanced age, genetics and lifestyle to name a few. To tackle this scenario, infertile and sub fertile couples take the aid of assisted reproductive technology. Intra uterine insemination (IUI), In vitro fertilization (IVF), Intra cytoplasmic sperm injection (ICSI), surgical sperm retrieval …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 95–103 Read article
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AI-Driven Precision Nutrition: Advancing Personalized Dietary Systems for Public Health Equity in Resource-Constrained Environments
Abstract: The dual burden of malnutrition and diet-related non-communicable diseases (NCDs) represents a growing global public health challenge, particularly in low- and middle-income countries. Traditional dietary guidelines are largely population-based and fail to account for individual variability in genetics, metabolism, lifestyle, and environmental exposure. This limitation has led to the emergence of precision nutrition, an evolving field that integrates biological data and computational intelligence to deliver personalized dietary recommendations. This paper …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 15, Issue 1, 2026 Read article