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284 articles for “acetate”
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Anthelmintic, Neuropharmacological and Analgesic Activities of Extracts from the Aerial Part of Eclipta alba L.
Abstract: The current study was aimed to investigate the anthelmintic, neuropharmacological and analgesic activities of extracts from the aerial part of the plant Eclipta alba L. (Family: Asteraceae). The anthelmintic activity was performed by observing the time of paralysis and the time of death of earthworms Pheretima posthuma compared with the standard drug, albendazole. The range of minimum to maximum time of paralysis and death of albendazole at the conc. 100 …
Published in Research & Reviews : Journal of Herbal Science · Vol. 5, Issue 1, 2016 · pp. 1–5 Read article
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A Review of Phytochemistry and Biological Activities of Anisomeles malabarica
Abstract: ABSTRACTThe oldest remedies known to mankind are herbal medicines. India is known worldwide for its Ayurvedic treatment. Ethno botanically, the leaves of the plant Anisomeles malabarica are used against convulsions, for dyspepsia in intermittent fevers, colic, boils, tetanus, inflammation, cough, cold, stomachache, itches and in uterine affections. Citral, betulinic acid, β-sitosterol, ovatodiolide, anisomelic acid, anisomelolide, malabaric acid, 2-acetoxymalabaric acid, anisomelyl acetate, anisomelol and anisomelin were present in the leaves of …
Published in Research & Reviews : Journal of Herbal Science · Vol. 1, Issue 1, 2012 · pp. 1–9 Read article
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Antibacterial Property of Crocus Sativus L.
Abstract: ABSTRACTCrocus sativus commonly called saffron has been used widely in Middle East and South East Asia as a drug to promote health and to fight diseases. Saffron though cultivated in different parts of the world, is mainly cultivated in Iran. It has wide range of medical uses such as antitumor, antifungal and antiinflammatory activities. Characteristic components of saffron are crocetin, picrocrocin and safranal that are responsible for color, bitter taste, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 1, Issue 1, 2012 · pp. 17–23 Read article
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Study of Calcium Oxide Nanoparticles Synthesized by Solvothermal Method
Abstract: Calcium oxide (CaO) nanoparticles have been synthesized by simple solvothermal method using a domestic microwave oven. The reaction of calcium acetate with urea in ethylene glycol and by adding different mole% of manganese acetate as dopant was studied. The structural and optical properties of the proposed nanoparticles were investigated. The structural properties were characterized by powder X-ray diffraction (PXRD) and scanning electron microscopy (SEM) analysis. The average particle size of …
Published in Research & Reviews : Journal of Physics · Vol. 8, Issue 3, 2019 · pp. 14–19 Read article
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Antibacterial Activity and Preliminary Phytochemical Screening of the Extracts of the Bark of Moringa oleifera
Abstract: Ethyl acetate, acetone, methanol and aqueous extracts of the bark Moringa oleifera were screened against the enteric pathogens isolates namely, Esherichia coli, Shigella sonnei and Salmonella enteritis. All the extracts other than aqueous extract showed antimicrobial activity with the methanol extract having the percentage of activity. Preliminary phytochemical screening revealed the presence of and tannins in the methanol extract. Keywords: Moringa oleifera, bark, antimicrobial activity, flavones, tannins
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 1, Issue 2, 2014 · pp. 1–4 Read article
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Phytochemical Screening and In Vitro Antibacterial, Antiarthritic Activity of Leaves of Azima tetracantha
Abstract: The leaves of Azima tetracantha belongs to (salvadoraceae) commonly known as “mulluchangu” in Tamil, it is a best known medicinal plant from ancient period. The plant has reported for many pharmacological actions such as antifungal, antibacterial, hepatoprotective, anti-inflammatory, antiulcer, antiarthritic, hypolipidemia, etc. The aim of the present study was to investigate Phytochemical screening and in vitro antibacterial and anti-arthritic activity of Azima tetracantha leaves in different solvents extract (hexane, chloroform, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 4, Issue 3, 2017 · pp. 6–12 Read article
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Synthesis and Biological Evaluation of Mannose Thiazolidinones
Abstract: In a one pot procedure, a series of novel mannose thiazolidinone derivatives 4a–g and 5a–g were prepared by condensation of (3aS, 4S, 6S, 6aS)-6-methoxy-2,2-dimethyltetrahydrofuro [3,4-d][1,3]dioxole-4-carbaldehyde-3 with mercapto acids and primary amines in presence of ZnCl2 under both micro wave irradiation and conventional heating conditions. Compound-3 was prepared from Methyl di acetone D-Mannose with primary acetonide deprotection and with oxidative cleavage. Characterization of new compounds has been done by means of …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 5, Issue 2, 2018 · pp. 38–46 Read article
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Synthesis and Chemical Characterization of Benzopyran Derivatives Fused to Pyrimidine Moiety
Abstract: In an attempt to find a new class of antimicrobial agents, a series of fused benzopyran derivatives containing pyrimidine moiety were prepared via the reaction of 2-(1h-benzo[d] imidazol-2-yl acetonitrile with 2-amino-3-(1h-benzo[d] imidazol-2-yl)-4-phenyl-4h-chromen-7-ol in the presence of piperidine and anhydrous zinc chloride. The target molecules were also synthesized using interchange component strategy. These compounds were screened for their antibacterial activity against gram-positive bacteria (Staphylococcus aureus and Streptococcus pyogenes), gram-negative bacteria (Pseudomonas …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 5, Issue 3, 2018 · pp. 11–23 Read article
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A Review on Herbal Drugs as an Analgesic
Abstract: Any group of drugs of diverse chemical structure and physiological effects which are commonly used for the relief of pain is referred to as analgesics. To qualify as an analgesic, a drug must selectively reduce or abolish pain without causing impairment of consciousness, mental confusion, in coordination or paralysis, or other derangements of the nervous system. Opium is the best-known class of narcotic alkaloid analgesics, a drug obtained by extracting …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 3, Issue 2, 2016 · pp. 15–22 Read article
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A New RP-HPLC Method for Simultaneous Estimation of Atorvastatin and Fenofibrate in Its Bulk and Tablet Dosage Form
Abstract: Objective: A New method was established for simultaneous estimation of Atorvastatin and Fenofibrate by RP-HPLC method. Methods: Chromatographic separations were carried using Phenomenex C18 column (4.6 × 250 mm, 5 µm) column with a mobile phase composition of 0.1 M Ammonium acetate:acetonitrile (60:40) have been delivered at a flow rate of 1ml/min and the detection was carried out using waters HPLC auto sampler, separation module 2695 with PDA detector at …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 8, Issue 3, 2023 · pp. 12–18 Read article
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HPTLC Method Development and Validation of Genistein and Daidzein Estimation in Mucuna cochinchinensis Seed Extracts
Abstract: Aim: The current study was designed with the objective to estimate the concentration of Genistein and Daidzein in ethyl acetate extract of Mucuna cochinchinensis by high-performance thin-layer chromatography (HPTLC).Methods: The separation of bioactive compounds was performed using mobile phase, Toluene: n-Butanol: Glacial Acetic Acid: Water (1:4:2:2) and detected at wavelength 254 nm. The method was validated for linearity, accuracy, precision, limit of detection (LOD) and limit of quantification (LOQ) by …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 1, 2020 · pp. 16–25 Read article
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Application of Prodrug to Improve Skin Permeability: A Review
Abstract: Administration of drug via skin has some limitations such as skin barrier, solubility of drug and partition coefficient etc. Stratum corneum which is an outer skin layer, acts as a barrier to the skin. Thus, prodrug has some applications to improve skin permeability. Prodrugs are defined as the compounds which are initially inactive but covert into their active form when reacted with several chemicals or enzymes at particular active site …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 8, Issue 1, 2023 · pp. 1–11 Read article
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A Comprehensive Review on Chitosan Anticancer Property
Abstract: Chitosan, a hydrophilic, natural amino polysaccharide derived from chitin on alkaline de-acetylation. Chitosan is a nontoxic, biocompatible, antibacterial and biodegradable polymer. The biological activities of chitosan are mainly depending on the water solubility nature and also the solubility in other solvents. The primary amino group present in the chitosan is the key functional groups which is mainly responsible for its bioactivities. The biological activities of antimicrobial, antioxidant and anticancer properties …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 2, 2020 · pp. 1–7 Read article
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Zeolite-Y Encapsulated Copper (II) and Cobalt (II) Species as Hybrid Nano-catalysts: Structural and Catalytic Aspects
Abstract: Special properties inherent to zeolites in facilitating the construction of novel upramolecular assemblies by encapsulation of guest molecules (metal complexes) into their large cages can be utilized to use these assembled materials as novel catalysts. These modified solids have the advantages of both behaving as the homogeneous and the heterogeneous catalytic system. In the present work, copper (II) and cobalt (II) complexes of 2-amino ethanoic acid (2-AEA) encapsulated in the …
Published in Journal of Catalyst & Catalysis · Vol. 10, Issue 4, 2023 Read article
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HPLC and Tandem MS Device for the Recognition of Emtricitabine and Tenofovir Alafenamide in K2EDTA Human Plasma Utilizing Emtricitabine 15ND2 Tenofovir D5 as an IS
Abstract: Developed very impressionable, discriminating, and exact extreme-efficiency liquid chromatographytandem bulk spectrometry form for measurement of Emtricitabine and Tenofovir Alafenamide in human plasma. Emtricitabine15ND2 Tenofovir D5 was used as a within the standard (IS). The samples were divided on Phenomenex Kinetex C18 5 μm 100A, 100*4.6 mm procession utilizing Acetonitrile: 0.2% formic acid, 60:40 V/V as movable state, the retention period of Emtricitabine: 1.36 minutes (±0.5 minutes), Emtricitabine 15ND2: 1.36 minutes …
Published in Research and Reviews: A Journal of Toxicology · Vol. 13, Issue 4, 2023 · pp. 30–38 Read article
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In Silico Molecular Docking of Indigofera tinctoria Phytocompounds to Target EGFR/ERK and FGFR/FGF Pathway Proteins Involved in Prostate Cancer
Abstract: Objective: Prostate cancer being the second major cause of cancer-related deaths in males, affects the small walnut-shaped gland below the bladder called the prostate gland. The epidermal growth factor protein (EGFR), cascade protein (ERK), and fibroblast growth factor proteins (FGFR and FGF) are involved in the different signaling pathways that lead to the formation of different products, that are responsible for the progression of cancer and thus can be considered …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 34–56 Read article
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An Integrated Study to Extrapolate the Interaction of NMDAR with Potential Ligands for the Treatment of Alzheimer’s Disease Symptoms
Abstract: Objective: Alzheimer’s disease (AD) is the most common neurodegenerative disease affecting the health status of older adults especially those above the age of 60 years. As an outcome, two types of medications have been developed for the treatment of its symptoms which are acetylcholinesterase (AChE) and N-methyl-D-aspartate receptor (NMDAR) antagonist. This paper uses the computational approach to understand the interaction of NMDAR with four major phytocompounds (curcumin, L-epicatechin, ginsenosides, and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 15–27 Read article
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Synthesis, Characterization and Antibacterial Activity of Mono- and Binuclear Co(II) and Cr(III) Mixed-Ligand Complexes Derived from α-Amino Acid and 1,10- Phenanthroline with 1,3-Diaminopropan as a Spacer
Abstract: Mixed-ligand complexes of Co(II) and Cr(III) ions were synthesized from the reaction of metals chloride salts with α-amino acid (H2L1) as a primary ligand and 1,10-phenanthroline (L2) as secondary ligand. The ligand 2-(benzo[d]thiazol-2-ylamino)-2-(2-hydroxynaphthalen-1-yl) acetic acid (H2L1) has been synthesized from the condensation reaction of inobenzothiazol with 2-hydroxy-1-naphthaldehyde in the presence of HCN as three components–one pot reaction. H2L1 considered as a tridentate chelater of ONO-coordination binding type toward the metals, …
Published in Journal of Polymer & Composites · Vol. 11, Issue 2, 2023 · pp. 107–120 Read article
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A Concurrent Estimation of Phytoconstituents Piperine, Quercetin and Kaempferol Present in Siddha Polyherbal Formulation Kabasara Kudineer by Rp-Hplc
Abstract: A straightforward, accurate, and precise technique was developed and validated for the simultaneous determination of Quercetin, Kaempferol, and Piperine in the polyherbal formulation Kabasura Kudineer. The sample was chromatographed using a C18 column (150x4.6mm, 5u) with a mobile phase composed of Acetonitrile and Ortho phosphoric acid in a 45:55 ratio, flowing through the column at a rate of 1ml/min. The detection wavelength for Quercetin, Kaempferol, and Piperine was set at …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 1–9 Read article
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A review on antibacterial properties of eucalyptus oil and different eucalyptus species used in pharmaceuticals
Abstract: Medicinal plants with antimicrobial compounds play a crucial role in combating various pathogens. Eucalyptus, belonging to the myrtle family, is notable for its diverse antimicrobial compounds. This fast-growing plant thrives in many countries and its various parts offer significant medicinal value, including timber, pulpwood, and essential oils. The leaves, often considered forest harvesting waste, contain essential oils with potential medicinal benefits. Members of the genus Eucalyptus are highly valued for …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 10–19 Read article