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784 articles for “Reaction”
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Modulation of Receptor Proteins: A Recent Paradigm in Drug Discovery and Target
Abstract: The main aim in drug discovery is to design different ligands those work on specific drug targets. However, various effective drugs work through the modulation of many proteins than single target. Advancement in system biology are establishing a phenotypic strength and a network structure, which suggests that, the excellent selective compounds may be performed less than desired clinical efficacy in comparison to multi-target drugs. In this new appreciation of the …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 1, 2018 · pp. 14–24 Read article
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ORIGINAL RESEARCH PAPER ON PROSPECTIVE OBSERVATIONAL STUDY FOR RISK OFPOLYPHARMACY PRESCRIPTION PATTERNS AT TERTIARY CARE HOSPITAl
Abstract: Background: Polypharmacy, the concurrent use of multiple medications, has become a prevalent concern in healthcare systems worldwide. This prospective observational study aimed to assess the relative risk and incidence of polypharmacy while investigating its impact on patient outcomes and exploring strategies for minimizing its irrational use. Forms for complete case reports and informed permission were used in the data gathering procedure. The study had 68 individuals in all, including both …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 13, Issue 2, 2023 · pp. 34–45 Read article
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Review On Natural And Synthetic Hair Dyes Available In International Market
Abstract: Natural and synthetic hair dyes are both available in the international market, and each type has its own advantages and disadvantages. Natural hair dyes are typically less harsh and safer for people with sensitive skin or allergies, but they can be less vibrant and long-lasting than synthetic hair dyes. Synthetic hair dyes are typically more vibrant and long-lasting, but they can be more damaging to the hair and scalp and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 14, Issue 2, 2023 · pp. 10–26 Read article
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SiRNA-Based Multivalent Vaccines: A Systematic Review of Potential Risks, Benefits, and Future Applications
Abstract: Background: Small interfering RNA (SiRNA) technology represents a promising innovation in vaccine development, especially for multivalent vaccines that can target multiple pathogens or antigenic variants simultaneously. siRNA-based vaccines offer a unique mechanism to induce specific immune responses, presenting an adaptable and potentially powerful tool for tackling infectious diseases and cancer. Methods: This systematic review synthesizes recent studies on siRNA multivalent vaccines, focusing on their immunogenicity, safety, and effectiveness. We reviewed …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 43–49 Read article
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Cow’s Milk Allergy: Prevalence, Diagnosis, and Alternative Formulations
Abstract: Cow’s Milk Allergy (CMA) occurs when the immune system reacts to proteins in cow’s milk, like casein and whey. In individuals with CMA, the immune system wrongly perceives these proteins as threats, causing allergic reactions when cow’s milk is consumed. Unlike lactose intolerance, which results from the body’s inability to digest lactose – a sugar in milk – due to a deficiency of the enzyme lactase, CMA is an immune …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 3, 2024 · pp. 22–26 Read article
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Tribological Assessment of Chemically Modified Jatropha Curcas Oil Developed by Addition of Graphite Nanoparticles for Biolubricant Applications
Abstract: As an alternative to petroleum-based lubricants, environmentally friendly bio-based lubricants are gaining popularity in the lubrication industry. A sustainable bio-based lubricant, Jatropha Curcas Oil (JCO) incorporates nanoparticles as additives. Nevertheless, this oil cannot be used directly as a biolubricant due to its low oxidative stability. By redesigning the oil's molecular structure through chemical modification, this restriction can be overcome. Epoxidation and oxirane ringopening were the two steps used in this …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 47–58 Read article
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Preparation of Organic Compounds by Microwave Technique with Applications
Abstract: Microwaves are an influential, reliable energy basis that may be adapted to several functions. Recognizing the fundamental technique following for microwaves will supply the chemical researchers with the right equipment and knowledge to be skilled to effectively apply microwave energy to any synthetic path. For chemical reactions and processes, microwaves offer an alternate energy source. Reaction mixtures are heated uniformly without coming into touch with walls using dielectric heating. While …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 2, 2025 · pp. 17–25 Read article
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Enhancing Mechanical and Durability Properties of Coconut Shell Concrete Using Fly Ash
Abstract: The increasing demand for sustainable and lightweight construction materials has driven research into alternative aggregates for concrete production. This study investigates the mechanical and durability properties of coconut shell (CS) concrete with varying percentages of fly ash replacement. The research evaluates compressive strength, split tensile strength, water absorption, and workability to determine the feasibility of CS concrete as a structural material. Experimental findings indicate that incorporating 10% fly ash (CSF10 …
Published in Recent Trends in Civil Engineering & Technology · Vol. 15, Issue 2, 2025 · pp. 19–24 Read article
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Red Earth Development of a Soil-Based Composite Using Bagasse Ash and Lime: Effects on Plasticity and Compaction Characteristics of Red Earth
Abstract: The concept of sustainable soil composites (SSC) emerges through blending red earth with bagasse ash (BA) and hydrated lime to enhance geotechnical properties and enable productive reuse of agro-industrial waste. Red earth functions as the matrix, BA acts as a fine pozzolanic microfiller, and lime serves as the chemical binder. BA content ranges from 0% to 60%, with 10% identified as optimal; subsequent lime additions from 1% to 5% evaluate …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 1147–1158 Read article
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DRUG INDUCED IMMUNE MEDIATED NEPHRITIS: MOLECULAR MECHANISM , PATHWAYS AND CLINICAL IMPLICATIONS
Abstract: Drug-induced immune-mediated nephritis (DI-IMN) has become a more widely known cause of acute kidney injury (AKI), with the potential for development to chronic kidney disease if not detected and treated promptly. T-cell hypersensitivity to pharmaceuticals, such as antibiotics, proton pump inhibitors, nonsteroidal anti-inflammatory drugs, and immunological drugs, are the major causes for it. Beyond clinical burden, DI-IMN reflectsintricate molecular interactions that sustain interstitial inflammation and tubular injury. These interactions include …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 13–29 Read article
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Growth of Cu2O on TCO by SILAR method acts as an alternative buffer electrode layer towards the development of organic solar cell
Abstract: In many types of optoelectronic devices, layer of PEDOT: PSS is sandwiched between the indium-tin oxide (ITO) electrode and the active layer. Buffer PEDOT: PSS provides a well- defined work function which is higher than that of ITO (4.2eV), it smooths the ITO surface and so avoids shorts, and it also protects the active layer from ingress of indium or oxygen, leading to longer device lifetimes. The role of PEDOT: …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 13, Issue 2, 2026 · pp. 20–27 Read article
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Synthesis of new heterocyclic compounds containing nitrogen, sulphur and study their biological activity
Abstract: Several substituted pyridines with brominated coumarin and with other substituents were achieved by condensing brominated coumarin IV with 4-methoxybenzaldehyde in basic solution forming α,β-unsaturated ketone II. Hantzsch reaction of this ketone with β-ketoester to provide precursor substituted pyridines. The Hantzsch reaction product was subjected to different reactions. The other targeted heterocyclic compound was obtained by reaction of α,β-unsaturated ketone II with hydrazine carbothioamide to give substituted pyrazole with brominated coumarin, …
Published in Emerging Trends in Chemical Engineering · Vol. 8, Issue 3, 2021 · pp. 8–16 Read article
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A New Protocol for The Synthesis of 5-(azidomethyl)-4-phenyl-1H- 1,2,3-triazole From Baylis-Hillman Adducts Derived from Nitro Olefins.
Abstract: The Baylis-Hillman adducts derived from nitroolefins have been convenientlytransformed into 5-(azidomethyl)-4-phenyl-1h-1,2,3-triazole via simple reaction condition. These compounds have been demonstrated for the synthesis of azidomethyl is highly biological reactive compounds. This novel bromo derivative of the BH adduct was simply treated with mole percentage of sodium azide in reactive condition. As a result, these novel azidomethylcompounds were extremely encouraging and provided fresh chances for building libraries of several new molecules. …
Published in Emerging Trends in Chemical Engineering · Vol. 9, Issue 2, 2022 · pp. 42–46 Read article
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Use of Modified and Unmodified Calcium Oxide from Bio-resources as Heterogeneous Transesterification Catalyst for Biodiesel Synthesis: A Review
Abstract: Metal oxides have been widely used to catalyze various types of organic reaction, whatever supported or nonsupport metal oxide catalysts (supported with metal, mixed oxides and acids such as sulphoric acid). Calcium oxide is one of the most metal oxides used as heterogeneous catalysts; due to its favorable properties such as high activity, availability, low cost, and easily separated, as well as environmental friendly. Calcium oxide whether laboratory, prepared from …
Published in Emerging Trends in Chemical Engineering · Vol. 9, Issue 3, 2022 · pp. 30–34 Read article
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Thermal Behavior of Biomass Ashes with the Influence of Additives: A Critical Review
Abstract: The gasification of biomass is undoubtedly one of the most promising processes for sustainable energy and heat production. The formation of low-melting ashes can compromise the proper functioning of plants. To address potential risks of ash fusion and agglomerate formation in high-temperature zones that may occur in downdraft reactor configurations, a detailed literature review on the use of additives to counteract the risk of ash formation and deposition has been …
Published in Journal of Alternate Energy Sources & Technologies · Vol. 14, Issue 3, 2024 · pp. 1–11 Read article
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Synthesis of Isoamyl Acetate (Banana oil) Using Fly Ash Supported Nano Crystalline Solid Acid Catalyst
Abstract: A novel fly ash supported solid acid catalyst (HClO4/FA) has been synthesized by using F-type fly ash and HClO4 as precursor. The variation of surface and physicochemical properties of the fly ash by activation methods resulted in improved acidity and therefore, catalytic activity for acid catalyzed esterification reactions. The HClO4/FA catalyst was characterized by XRF, XRD, FT-IR, SEM and BET surface area. The catalytic performance of HClO4/FA catalyst was evaluated …
Published in Journal of Catalyst & Catalysis · Vol. 4, Issue 2, 2017 · pp. 1–8 Read article
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Synthesis of Biodiesel from Biowaste/Vegetable Oil by Using Heterogeneous Nano-Catalyst
Abstract: This paper presents preparation of heterogeneous nanocatalyst (NaOH/ZnO-Li2CO3) for biodiesel synthesis from biowaste/vegetable oil by transesterification. Transesterification is an important reaction that produces fatty acid methyl esters which are excellent substitutes for diesel fuel. Biodiesel production by using nanocatalyst is one of important approaches in the biofuel research. The optimization of transesterification reaction is affected by the catalyst type, reaction temperature, reaction time, methanol to biowaste/oil ratio. The analysis of …
Published in Journal of Catalyst & Catalysis · Vol. 4, Issue 1, 2017 · pp. 11–23 Read article
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Thermodynamic, Kinetic and Mechanistic Investigations of Ruthenium(III) Catalyzed Methylparaben Oxidation by Diperiodatocuprate(III) in Aqueous Alkaline Medium
Abstract: The kinetics of ruthenium(III) catalyzed degradative oxidation of methylparaben by the copper complex, diperiodatocuprate(III) in alkaline medium is studied at 25ºC and at a ionic strength of 8.0 × 10−2 mol dm−3. In the presence of catalyst ruthenium(III), the reaction between methylparaben and diperiodatocuprate(III) in aqueous alkaline medium exhibits 1:1 stoichiometry. The oxidation products were identified by UV-visible, GC-MS and IR spectroscopy. The reaction exhibited unit order in case of …
Published in Journal of Catalyst & Catalysis · Vol. 2, Issue 1, 2015 · pp. 4–17 Read article
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Ru(III)-Catalyzed Oxidative Cleavage of Ritodrine Hydrochloride: A Kinetic and Mechanistic Study
Abstract: A systematic kinetic and mechanistic study of the oxidation of ritodrine hydrochloride (RTH) with chloramine-T (CAT) in both HClO4 and NaOH media has been carried out at 303 K. In acid medium, the reaction rate is very sluggish to be measured kinetically. Ruthenium (III) chloride ([Ru(III)]) was found to be an efficient catalyst. The reaction rate exhibits a first-order dependence on [CAT]0 in both media. It shows a fractional-order on …
Published in Journal of Catalyst & Catalysis · Vol. 1, Issue 1, 2014 · pp. 29–40 Read article
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Synthesis of Biodiesel fuel additive from Glycerol using Cationic ion exchange resin- A review
Abstract: With the alarming increasing of oil consumption and the number of automotives being instilled, there has been immense research taking place to find a sustainable fuel to replace the current fossil fuels and also not render the current automotives obsolete. The current favorable solution to this is Biodiesel which can be generated either from oil seeds or waste vegetable oils. The selectivity of this process is 90% and the byproduct …
Published in Journal of Catalyst & Catalysis · Vol. 6, Issue 3, 2019 · pp. 1–8 Read article