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395 articles for “Promising approach”
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Kisunla (Donanemab): A Novel Breakthrough Illuminating a Path to Better Alzheimer’s Outcomes
Abstract: Background: Alzheimer’s disease (AD) is a progressive neurodegenerative condition marked by cognitive decline, memory loss, and loss of independence. Despite decades of extensive research, disease-modifying treatments have been limited in success. Recent therapeutic advancements have led to the development of monoclonal antibodies targeting amyloid-beta (Aβ) plaques, particularly the pyroglutamate-modified variant, a key pathological hallmark of AD. Objectives: This review aims to explore the therapeutic potential of Donanemab (Kisunla), a novel …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 3, 2025 · pp. 37–45 Read article
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Host Invasion to Immune Evasion: Emerging Concepts in Pathogen Virulence Strategies
Abstract: The interaction between hosts and pathogens represents a continuous evolutionary struggle, shaping both microbial virulence and host immunity. Pathogens employ diverse strategies to evade immune surveillance, ranging from antigenic variation and molecular mimicry to hijacking of host immune checkpoints. Simultaneously, hosts refine innate and adaptive immune mechanisms to counteract infection and limit damage. This reciprocal adaptation, known as host–pathogen coevolution, influences pathogen persistence, transmission, and fitness, while also sculpting immune …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 Read article
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Nanotechnology in Medical Applications: A Study
Abstract: In the field of medicine, nanotechnology has a wide range of applications that are both transformational and expansive. These apps provide solutions which have an opportunity to significantly enhance the outcomes of treatment and to provide better care for patients. The potential benefits are enormous, ranging from the delivery of drugs in a targeted manner to the development of sophisticated diagnostics and regenerative medicine. The incorporation of nanotechnology into clinical …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 2, 2024 · pp. 1–11 Read article
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AI-Assisted Defect Detection in Polymer Composite Insulators Using an Optimised Ensemble Deep Learning Framework for Structural Health Monitoring
Abstract: Polymer composite insulators, particularly those made from silicone rubber and epoxy resins, are increasingly adopted in high-voltage transmission systems due to their superior electrical insulation, lightweight design, hydrophobicity, and environmental durability. Despite their advantages, these materials are susceptible to surface degradation, mechanical cracking, and flashover under prolonged exposure to environmental pollutants, thermal stress, and electrical aging. Accurate, real-time condition assessment of these composite insulators is critical for ensuring operational safety, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 253–261 Read article
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Enhancing the User Experience of Asthma Inhalers: A Redesign Approach
Abstract: Asthma is a widespread chronic respiratory condition impacting millions globally, presenting significant challenges in its management and treatment. While conventional inhalers effectively administer medication, they often encounter usability issues, hindering patient adherence and treatment outcomes. This abstract delineates the development and potential impact of a redesigned asthma inhaler aimed at addressing these challenges. Incorporating human-centered design principles, the revamped inhaler prioritizes usability, portability, and effectiveness to enhance the overall management …
Published in International Journal of Solid State Innovations & Research · Vol. 1, Issue 2, 2023 · pp. 32–36 Read article
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Role of Low Level Laser Therapy (LLLT) in Healing of Electric Burns
Abstract: The objective of this case study is to evaluate the effectiveness of low-level laser therapy (LLLT) in treating scalp wounds caused by electric burns. A thorough examination of the scalp wound was conducted both before and after administering LLLT. The findings suggest that LLLT plays a beneficial role in the healing process of superficial ulcers. Specifically, the application of LLLT (as depicted in Figure 1) demonstrated promising results in facilitating …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 2, 2024 · pp. 39–44 Read article
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Deep Learning Enhanced Compressive Sensing for Wireless IoT Data Optimization and Weather Monitoring.
Abstract: This research explores the application of deep learning and compressive sensing in order to optimize data traffic in non-orthogonal multiple access (NOMA)-based wireless internet of things (IoT) networks and weather monitoring. Such a framework would be very effective and overcome pilot attacks and reconstruction losses for secure data transmission. In this regard, a strong communication model has been adopted based on power-domain NOMA for simultaneous wireless transmission by multiple IoT …
Published in International Journal of Satellite Remote Sensing · Vol. 2, Issue 2, 2024 · pp. 20–36 Read article
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Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
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Offloading Computation to the Cloud
Abstract: Mobile devices are increasingly relied upon for complex and resource-intensive applications such as real-time video processing, augmented reality, and machine learning. However, their limited computational power, storage capacity, and battery life pose significant challenges. Computation offloading to the cloud has emerged as a promising solution to overcome these limitations by transferring demanding tasks from mobile devices to remote cloud servers. This approach enables improved performance, reduced energy consumption, and enhanced …
Published in International Journal of Mobile Computing Technology · Vol. 3, Issue 2, 2025 · pp. 27–37 Read article
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Internet of Battlefield Things (IoBT): An IoBT-inspired Battlefield of Tomorrow
Abstract: The battlefield of tomorrow will be radically different from the ones we know today. The internet of battlefield things (IoBT) is a game-changer in modern warfare. By providing enhanced situational awareness, improved decision-making, and new capabilities for soldiers, IoBT empowers military forces to operate more effectively and efficiently. However, it is crucial to address challenges related to cybersecurity, interoperability, and implementation to fully harness the potential of this revolutionary technology. …
Published in Journal of Telecommunication, Switching Systems and Networks · Vol. 11, Issue 3, 2024 · pp. 18–25 Read article
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Enhancing Smart Grid Security: Machine Learning Approaches for Detecting Anomalies
Abstract: The integration of Information and Communication Technology (ICT) with traditional electric grids has led to the development of smart grids. However, this integration has also increased the risk of anomalies, such as cyber-attacks, metering fraud, electricity theft etc. False Data Injection Attacks are a class of cyber-attacks against power grid monitoring systems, where adversaries can inject false data to manipulate the grid’s operation. Metering frauds pertain to malicious customers com- …
Published in Trends in Electrical Engineering · Vol. 14, Issue 2, 2024 · pp. 10–19 Read article
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Investigation of Migraine
Abstract: Individual's medical history, and any potential side effects that may occur. It is also important to consult with a healthcare provider before beginning any new treatment plan, as they can provide guidance on the best course of action based on the individual's specific needs and circumstances. In addition to medication, individuals with migraines can explore various treatment avenues. Lifestyle modifications, such as incorporating regular exercise, maintaining a healthy diet, managing …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 38–45 Read article
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Harnessing Nature: Formulations for Colon Cancer Prevention and Treatment
Abstract: Colon cancer, a rapidly advancing disease worldwide, involves the carcinogenesis of the distal part of the intestine. This malignancy progresses through various developmental stages necessitating diverse treatment approaches. Traditional treatments include drug therapy and chemotherapy; however, emerging methods, such as the use of phytochemical compounds offer promising mechanisms for combating this disease. Phytochemical compounds derived from natural food sources, including flavonoids, tannins, resveratrol, and epigallocatechin-3-gallate, exhibit potent anti-cancer properties. They …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 3, 2024 · pp. 11–23 Read article
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Flaxseed-Based Drug Delivery Systems: Advancing Colon Cancer Treatment
Abstract: Flaxseed (Linum usitatissimum) has long been appreciated for its rich nutritional profile, including essential fatty acids (such as α-linolenic acid), plant fibers, and lignans. Recent research has focused on its potential as a novel drug delivery system (DDS) for the treatment of colon cancer. This review explores the bioactive constituents of flaxseed, their pharmacological activities, and innovative approaches to the use of flaxseed extracts in drug delivery for the treatment …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 54–59 Read article
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The Early Brain Hemorrhage Prediction System Using Machine Learning
Abstract: Brain hemorrhage is a critical medical emergency that requires immediate attention, as delays in diagnosis can result in severe neurological damage or death. The condition involves bleeding within or around brain tissues, leading to increased intracranial pressure and disruption of normal brain function. Although imaging techniques such as CT scans and MRI provide accurate diagnosis, their availability is limited in emergency and rural settings. In recent years, machine learning has …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 16, Issue 2, 2026 Read article
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Synthesis of Silver Nanoparticles of Cissus Quandrangularis and It’s Virtual Screening Against Gastric Cancer
Abstract: Gastric cancer, also known as stomach cancer, is the third leading cause of cancer-related deaths globally and remains a major health challenge due to its poor prognosis and high mortality, largely attributed to late-stage diagnosis. In this context, plant-based nanomaterials are gaining momentum for targeted therapeutic applications. Cissus quadrangularis, a medicinal plant native to India from the Vitaceae family, is traditionally used for its diverse healing properties. Its stem, in …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1551–1569 Read article
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FMR1 Key Biomarker in Fragile X Syndrome- A Comprehensive Review
Abstract: Fragile X Syndrome (FXS) is a complicated neurodevelopmental condition that causes intellectual disabilities, behavioural issues, and a variety of physical symptoms. Central to understanding FXS is the Fragile X Mental Retardation 1 (FMR1) gene, pivotal in the disorder's pathogenesis. This review examines FMR1 as a key biomarker in FXS, drawing on recent research insights. The FMR1 gene, situated on the X chromosome, encodes the fragile X mental retardation protein (FMRP), …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 8–18 Read article
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Synthesis and Characterization of Polymer-Based Benzamide Derivatives with Potential Biomedical Applications
Abstract: The present study explores the synthesis and characterization of polymer-supported benzamide derivatives, focusing on their potential biomedical applications. The use of polymer-supported synthesis offers several advantages, including improved reaction efficiency, ease of purification, and reusability of the support material, making it an environmentally friendly and cost-effective approach. The synthesis involved a stepwise reaction sequence, with polymeric supports facilitating controlled functionalization and ensuring high product purity. These materials have been widely …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 Read article
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Forecasting Commodity Prices Using Deep Learning Techniques: An Empirical Evidence from India
Abstract: Commodity price forecasting is instrumental in financial markets, providing framework for investment choices and risk management practices. Traditional models, including statistical and machine learning approaches, have limitations in capturing the nonlinear and volatile nature of commodity prices. Deep learning (DL) techniques have emerged as promising alternatives, leveraging advanced neural networks to enhance predictive accuracy. This study presents a thorough and comprehensive examination of deep learning applications in commodity price prediction, …
Published in Journal of Computer Technology & Applications · Vol. 16, Issue 3, 2025 · pp. 08–12 Read article
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Next-Generation Polymer Recycling for Circular and Sustainable Plastics
Abstract: Plastic waste has emerged as a serious global environmental issue because of the enormous quantities produced over the past several decades. Moreover, the continual rise in plastic production, coupled with low recycling rates, results in the steady accumulation of plastic in the environment each year. In addition, manufacturing new polymers consumes substantial amounts of energy and fossil fuel resources. Although renewable energy can reduce emissions to a great extent, still …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 517–526 Read article