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161 articles for “In silico”
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Iota carrageenan, a Sustainable polymer transformed into a nanogel formulation, by using environment friendly method for antitumor action
Abstract: In the pharmaceutical field, the utilization of polymers, both in their natural form and through chemical modifications, holds immense importance. In this context, a novel and eco-friendly method for the synthesis of nano carrageenan-based polymers has been developed. The efficacy of carrageenan in this domain is attributed to its crosslinking and biological properties, which are largely influenced by its sulfate ion content. This study aims to formulate nanogels via a …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 881–889 Read article
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Mechanical Strength Prediction of Nano-Silica Concrete Composites Using Machine Learning Techniques
Abstract: Nano-silica, or nanosilica, refers to silicon dioxide nanoparticles, which are a kind of silica (SiO₂) with diameters that often fall below 100 nanometers. This nanomaterial has attracted considerable attention because of its distinctive characteristics and diverse array of uses, notably in augmenting the performance of materials such as concrete. The integration of nanoparticles with cementitious matrix in nano-silica concrete offers a viable approach to improving the mechanical characteristics and longevity …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 963–973 Read article
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Exploring Azadirachta indica’s Potential to Combat Visceral Leishmaniasis Through GP63 Inhibition
Abstract: Objectives: Millions of people worldwide suffer from the parasite disease visceral leishmaniasis. Determine the naturally occurring active ingredients in Azadirachta indica, which are employed as a disease-prevention agent and have several uses in medicine. To choose the best ligand to use as a medication, absorption, distribution, metabolism, and excretion (ADME) studies and molecular docking are employed. Methods: To obtain the GP63 protein, the Protein Data Bank (PDB) database was accessed. …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 1–12 Read article
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Exploring the Role of Thin Film Coatings in Solar Energy Harvesting
Abstract: With notable gains in efficiency, longevity, and affordability, thin film coatings have become a key technology in the field of solar energy harvesting. These coatings, typically composed of materials like titanium dioxide (TiO₂), cadmium telluride (CdTe), and amorphous silicon (a-Si), are applied to photovoltaic (PV) cells to enhance their ability to absorb and convert sunlight into electricity. This review article delves into the various types of thin film coatings used …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 11, Issue 2, 2024 · pp. 15–19 Read article
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Significance of Composite Materials for Making Better Future Society
Abstract: Since in the beginning of human history, Materials had been started in use. We can't imagine our world without materials. In fact, Materials has taken centre position in many developed and developing countries. The materials that humans have chosen to use for engineering projects throughout history, including the Stone, Iron, and Silicon ages. However, in order to meet today's difficulties, new materials must be discovered and developed with the necessary …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 2, 2023 · pp. 56–62 Read article
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Evaluating the therapeutic effects of Asystasia gangetica (Chinese violet) on the chronic respiratory condition- Asthma
Abstract: Asthma is a chronic condition affecting the respiratory system. Its symptoms affect the immune pathways via helper T-cells. The plant Asystasia gangetica is prevalent throughout tropical regions around the world. It has been used in some herbal remedies to relieve symptoms of asthma. This study used computational techniques to assess the effectiveness of several phytocompounds present in A. gangetica in relieving symptoms of Asthma. Three proteins associated with asthma, namely …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 1, 2025 · pp. 15–21 Read article
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Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
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Enhancing The Mechanical Performance of Al6061/Graphite Composites Reinforced with Sic and Aluminium Oxide Processed by Stir Casting
Abstract: The study investigates the mechanical properties of aluminum alloy Al6061 reinforced with varying proportions of silicon carbide (SiC) (0 wt%, 4 wt%, 5 wt%, and 6 wt%) and aluminum oxide (Al₂O₃) (0 wt%, 4 wt%, 3 wt%, and 2 wt%), with a constant addition of 1 wt% graphite. The composites were fabricated using the stir casting process, an efficient and economical method for uniformly distributing ceramic reinforcements within the metal …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 66–74 Read article
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Investigation of Mechanical Behaviour in Brake Shoe Liner by Using Composite and Nano Materials
Abstract: The mechanical performance of the brake shoe liners dictates the safety and efficiency of the vehicles; thus, brakes are very vital in ensuring controlled deceleration and stopping. In the past few decades, composites have significantly impacted the automotive industry through lighter, stronger, and sturdier alternatives to traditional materials improving overall performance. Nano additives are of key importance in such composites, improving not only the mechanical properties but, more significantly, the …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 280–295 Read article
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Modeling of ZnO Based Nano Sensor Device for Evaluating Electronic Interaction with NO2 Pollutant: Combining Multiphysics Simulation and DFT Study
Abstract: This study focuses on the designing and modeling of a sensor device employing zinc oxide (ZnO) nanowires (NWs), and the evaluation of the chemical response of the same in the presence of nitrogen dioxide (NO2), which is an acute harmful pollutant for human health and environment. Experimentally synthesized ZnO nanostructures were used as the basis for modeling of the ZnO NWs based sensor device along with a single ZnO NW, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 211–219 Read article
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Fabrication and Analysis of Al 7075 Based Metal Matrix Composites - A Review
Abstract: Aluminium 7075 alloys are extensively used in aerospace, marine, aviation, and automotive industries due to their superior mechanical properties, high strength-to-weight ratio, and low density. However, to further enhance their performance, aluminium-7075 metal matrix composites (AMMCs) are developed by incorporating various reinforcements. This paper focuses on the influence of reinforcements on the mechanical, tribological, and corrosion behavior of AMMCs. The study examines fabrication techniques, particularly the stir casting method, which …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 1–12 Read article
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Advancements In Al6061 Metal Matrix Composites: The Role of SiC, Al₂O₃, and Graphite Reinforcements in Enhancing Properties and Applications
Abstract: Al6061-based metal matrix composites (MMCs) reinforced with silicon carbide (SiC), graphite (Gr), and aluminum oxide (Al₂O₃) exhibit a unique combination of mechanical, thermal, and tribological properties, making them highly suitable for advanced engineering applications. SiC enhances hardness, wear resistance, and load-bearing capacity, while Al₂O₃ improves thermal stability and mechanical strength. Graphite provides self-lubricating properties, reduces friction, and lowers the composite's density, improving fatigue resistance. The synergy of combining these reinforcements …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 90–98 Read article
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First Insights into Whole Genome Sequencing of the Mycobacterium tuberculosis Complex: Molecular Diversity and Drug Susceptibility Patterns in Senegal
Abstract: Background: We conducted a bibliographic analysis of the Mycobacterium tuberculosis complex (MTBC) in sub-Saharan Africa, which included the analysis of 8,139 genomic sequences from 34 of the 49 sub-Saharan African countries. Notably, only one complete sequence from Senegal was identified, which had been generated in the United States. Our primary objective was to utilize whole genome sequencing (WGS) to detect resistance in anti-tuberculous strains of the MTBC in Senegal. This …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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An Experimental Investigation of Process Parameters for Aluminum Alloy Composites
Abstract: The objectives of this work are to develop an aluminum alloy composites and investigate machining process parameters effect on the tool wear rate for composites. The composite is enhanced using silicon carbide and graphite. The composite is made by a method called stir casting. Furthermore, it is investigated both mathematically and experimentally. This study takes trial on aluminum alloy composite to see output characteristics tool wear rate are affected by …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 185–193 Read article
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Performance Comparison of Noise-Tolerant, High- Performance CMOS Domino Logic Configurations
Abstract: In high-performance VLSI chip design, domino logic configuration is often preferred over static logic due to its faster operation and smaller area footprint, especially in deep submicron (DSM) technology. However, DSM noise has become a significant challenge in domino-based circuits, leading to compromises in the reliability and signal integrity of integrated circuits (ICs). The switching threshold of domino logic, defined as the input voltage level at which the gate output …
Published in Journal of Semiconductor Devices and Circuits · Vol. 12, Issue 2, 2025 · pp. 35–50 Read article
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Needle Choice in Spinal Anaesthesia: Is the 25-Gauge Whitacre Superior to the Quincke in Reducing Post-Dural Puncture Headache
Abstract: The process known as endotracheal intubation involves inserting a synthetic tube into the trachea and inflating the former's cuff to create an airtight seal. Of all the specialised masks in the LMA family, the PLMA is the most intricate. The cuff, the airway tube, the drain (gastric access) tube, and the inflation line with pilot balloon are its four primary components. This drain tube aids in identifying mask malposition and …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 Read article
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Polymer Chemistry in Flexible Dental Assemblies: Designing a Polymer-Based Composite Arm for Bio-Fluid Extraction Tube Support
Abstract: Polymer chemistry offers innovative solutions for designing flexible, durable assemblies in medical applications. This study explores an assembly for holding a bio-fluid extraction tube, featuring a flexible arm interpreted as a polymer composite, aimed at enhancing dental procedures. The assembly comprises a gooseneck-style arm—hypothesized as a rubber or fiber-reinforced polymer—connecting a first clamp (for anchoring to an object, e.g., dental chair) and a second clamp (securing the extraction tube). The …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 285–292 Read article
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Polymer Chemistry-Driven Design of a Severable Dental Prophylaxis Instrument: Leveraging PEEK and Composites for Enhanced Functionality
Abstract: Polymer chemistry unlocks new possibilities for dental prophylaxis instruments by leveraging molecular design for enhanced functionality. This study explores Polyether Ether Ketone (PEEK), a semi-crystalline thermoplastic, in a novel instrument with a severable working end, featuring a tubular structure with internal screw threads (0.5–0.8 cm) anchoring replaceable elements via a threaded mechanism. PEEK’s aromatic backbone, alternating ether and ketone groups, yields a tensile strength of ~100 MPa, chemical inertness against …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 869–877 Read article
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Dielectric Elastomers in Actuation and Energy Applications: Material Behavior and Design Strategies
Abstract: Dielectric elastomers (DEs), a class of electroactive polymers, have attracted significant attention for their ability to undergo large, reversible deformations under electric stimulation. This unique capability makes them highly suitable for a range of actuation and energy harvesting applications, especially in the emerging fields of soft robotics, flexible electronics, artificial muscles, and sustainable power generation systems. DEs offer compelling advantages such as low weight, mechanical flexibility, high energy density, and …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 3, Issue 1, 2025 · pp. 13–18 Read article
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Life Cycle Assessment of Solar Panels: Environmental Impacts from Production to Disposal
Abstract: LCA is a way to evaluate the full environmental impact of something—like a product, material, activity, or building—from start to finish. As solar energy adoption accelerates globally, understanding the full environmental implications of PV technology becomes crucial for informed decision-making and sustainable development. The study employs a cradle-to-grave approach, analyzing the environmental footprint of solar panels across multiple impact categories. These include global warming potential, energy payback time, water consumption, …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 3, Issue 2, 2025 · pp. 33–38 Read article