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169 articles for “Immune response”
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Food Allergy-practical Approach
Abstract: There is a consistent increase in prevalence of food allergy (FA). The diagnosis of FA is based on thorough history supported by positive skin test, specific IgE (extract-and component-based), Basophil activation test (BAT) to reduce the need for Oral food challenge (OFC). OFC procedures may be conducted in cases of diagnostic uncertainty or to assess the presence or development of tolerance. Effective management of food allergy involves a comprehensive three-pronged …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 1, 2024 · pp. 32–53 Read article
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DMARDs, Biologic Agents and Novel Experimental Strategies in The Treatment of Rheumatoid Arthritis
Abstract: An inflammatory and autoimmune disease, rheumatoid arthritis (RA) causes severe pain and inflammation in affected areas of the body. According to the report, there is no known cure for RA. Therefore, reducing discomfort and halting future harm must be the goals of present therapy. For the purpose of prevention and to reduce disease activity in RA patients, significant success has been achieved with the continued development of disease-modifying antirheumatic drugs …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 14–24 Read article
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SIBR/Aloe barbadenis Mill.: A Review on Medicinal Utility from the Perspective of Unani Medicine
Abstract: Aloe barbadensis Mill., known as Sibr in Unani medicine, is a time-honored medicinal plant belonging to the family Liliaceae. Revered across cultures and healing systems, it has been extensively described in Unani literature under various names such as Elwa, Musabbar, and Ghikwar. This review aims to comprehensively explore the medicinal utility of Sibr from an Unani perspective while integrating evidence from modern pharmacognosy, phytochemistry, and pharmacology. Traditionally, the dried juice …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 3, 2025 · pp. 22–29 Read article
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Hybrid Intelligence in Cyber Security: A Study
Abstract: The digital landscape is a battlefield of escalating complexity, where the volume, velocity, and sophistication of cyber threats have exponentially outpaced human-centric defense models. Traditional rule-based security systems and siloed artificial intelligence (AI) solutions, while valuable, are increasingly brittle, overwhelmed by zero-day exploits, polymorphic malware, and coordinated, state-sponsored campaigns that operate in the shadows of big data. This paper posits that the paradigm of cybersecurity must fundamentally shift from one …
Published in International Journal of Wireless Security and Networks · Vol. 4, Issue 1, 2026 · pp. 01–09 Read article
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Biopolymer-Based 3D Composite Scaffolds for Bone Tissue Engineering: Photothermal-Responsive Systems with Controlled Pt (IV) Prodrug Release
Abstract: Biopolymer-based composite scaffolds have attracted significant attention as multifunctional platforms at the intersection of polymer science, regenerative medicine, and cancer nanotherapy. In this study, a dual-functional scaffold was developed for simultaneous osteosarcoma treatment and bone regeneration using poly (L-lactic acid) (PLLA) reinforced with bioactive glass (BG) and integrated with a glutathione-responsive platinum (IV) prodrug system (PDA@Pt). To improve interfacial adhesion, photothermal conversion efficiency, and tumor-specific activation, the Pt (IV) prodrug …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 351–361 Read article
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Transplanting Hope: Organ Transplantation’s Science and Humanity
Abstract: One of the most revolutionary developments in contemporary medicine is organ transplantation, which provides patients with end-stage organ failure with both life-saving and life-improving options. The science and humanity of organ transplantation are examined in this article, which also looks at the ethical, social, and emotional factors that influence the area as well as the medical concepts that make transplants successful. It examines the biological underpinnings of immunosuppression and organ …
Published in Research and Reviews : Journal of Surgery · Vol. 15, Issue 1, 2026 · pp. 36–41 Read article
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Ebola Vaccination: From Outbreak Control to Global Preparedness
Abstract: Ebola virus disease (EVD) is one of the most dreadful and lethal viral infections, continuously generating threatening impacts on the health of the global population, especially in low-resource environments. This review provides an overview of Ebola vaccines, focusing on virology, vaccine development, clinical trials, regulatory approval, deployment plans, and ethical issues. Recombinant viral vector platforms have seen the development of successful vaccines, with the most prominent example being rVSV-ZEBOV, which …
Published in International Journal of Vaccines · Vol. 3, Issue 1, 2026 · pp. 27–37 Read article
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“Review Article on Tridax Procurmbens Herbal Antibacterial Cream”
Abstract: Abstract Tridax procumbens (L.), also referred to as coat buttons or tridax daisy, is a common plant in the Asteraceae family that is well-known for its exceptional pharmacological and therapeutic properties. This plant has long been utilized as an anticoagulant, antifungal, insect repellent, wound healer, and hepatoprotective agent in Indian Ayurveda. With a focus on its medicinal and formulation features, the current study offers a thorough summary of its botanical …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 1, 2026 · pp. 21–29 Read article
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Pathogens in Nosocomial Infections: Epidemiology, Resistance, and Control Measures
Abstract: Nosocomial infections, also known as healthcare-associated infections (HAIs), are a serious global health issue, leading to higher patient morbidity, prolonged hospital stays, and increased medical costs. Various pathogens—such as bacteria, viruses, fungi, and parasites—are responsible for these infections, especially in healthcare environments where they easily spread. They can be transmitted through direct contact with infected patients, contaminated medical equipment, or even airborne particles.Patients with weakened immune systems, those requiring prolonged …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 12–16 Read article
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Review of Current Trends in Vaccine Development against Zoonotic Viruses: Challenges and Innovations
Abstract: The emergence of zoonotic viruses poses a significant threat to global public health, necessitating rapid advancements in vaccine development. This review highlights the current trends and innovative strategies employed in the creation of vaccines against zoonotic pathogens, including but not limited to viruses responsible for diseases such as Ebola, Zika, Nipah, and more recently, SARS-CoV-2. We discuss various vaccine platforms, including inactivated, live attenuated, mRNA, and viral vector vaccines, focusing …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 1–11 Read article
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Host Interface of Cystic Fibrosis and P. aeruginosa
Abstract: A clash between microbial infection and host immunity can contribute to multiple diseases. Cystic fibrosis is one of those diseases. It’s an autoimmune disorder and hyperinflammatory disease, caused by pseudomonas aeruginosa, it’s the most predominant pathogen causing this disease. The progression of the lung infection cystic fibrosis is driven by host pathogen interface that focuses on the host and the bacterial factors. The disease has an interplay between the host, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 3, 2024 · pp. 9–31 Read article
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Demodex spp. (Acari: Demodicidae) Infestation in Humans: Diagnostic Clues and Therapeutic Approaches to Primary and Secondary Demodicosis.
Abstract: Demodicosis represents an inflammatory dermatosis and adnexal disorder arising from pathologic overgrowth of Demodex mites, primarily Demodex folliculorum and Demodex brevis, which are ubiquitous human ectoparasites residing in pilosebaceous units and eyelid margins. Once regarded as benign commensals, these mites are now recognized as primary drivers or key cofactors in diverse clinical phenotypes, including papulopustular eruptions, pityriasis folliculorum, rosacea-like disorders, blepharitis, meibomian gland dysfunction, and exacerbations of comorbid dermatoses such …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 12–20 Read article
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Cis-9, Trans-11 Conjugated Linoleic Acid in Milk: Natural Sources, Nutritional Advantages, and Potential Health Benefits
Abstract: Cis-9, trans-11 conjugated linoleic acid (CLA) is the most common type of CLA found in milk. It has gained a lot of attention because it may have several health benefits. This bioactive lipid is primarily derived from ruminal biohydrogenation of dietary linoleic acid and endogenous synthesis in the mammary gland via Δ9-desaturase activity. Various dietary and management strategies influence CLA concentrations in milk, including forage composition, lipid supplementation, and grazing …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
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Nanomedicine in the Tumor Microenvironment: Physiological Modulation Through Tissue Engineering Approaches
Abstract: The integration of nanomedicine and tissue engineering offers transformative strategies for cancer therapy by directly modulating the physiological processes within the tumor microenvironment (TME). This review emphasizes recent advances in nanomedicine that enable precise drug delivery, controlled release, and real-time monitoring of key physiological parameters influencing tumor progression, angiogenesis, and immune evasion. Tissue-engineered 3D tumor models provide physiologically relevant platforms that better mimic in vivo conditions than traditional 2D cultures, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 1, 2026 · pp. 19–31 Read article
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Trichoderma: beneficial fungus for sustainable agriculture
Abstract: As environmentally beneficial substitutes for chemical pesticides, Trichoderma species are being utilized in agriculture more and more. Disease suppression, increased plant growth, and increased tolerance to environmental stress are just a few advantages they provide. These fungi are used in a wide range of cropping systems and formulations around the world. Their use is growing worldwide, particularly in Asia and Europe. In contemporary crop management, items derived from Trichoderma are …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 · pp. 25–29 Read article
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In Vivo Biocompatibility and Interfacial Stability of Thermoplastic Polyurethanes and Nanofilled Resin Composites: A Bioanalytical Study of Polymer-Host Interactions Under Dynamic Loading
Abstract: The widespread application of thermoplastic polyurethanes (TPU) and nanofilled resin composites in biomedical devices requires rigorous assessment of their biocompatibility under mechanical stress. While nanofilled composites utilize filler particles (<100 nm) to enhance surface properties and wear resistance, the biological response to these materials in a hydrolytic, enzymatic environment remains a critical area of investigation. Objective: To analyze the in vivo bio-molecular response at the interface of TPU aligners and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1112–1119 Read article
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Perspectives on ‘Kamsaharitaki’: an Ayurvedic Formulation for COVID-19 related Multisystem Inflammatory Syndrome (MIS)
Abstract: Background and Aim: Angiotensin-converting enzyme 2 receptor (ACE2), together with Transmembrane protease serine 2 (TMPRSS2), is a protein receptor for SARS-CoV-2 virus in the host subject; expression of ACE2 and TMPRSS2 reveals the multidimensional character of COVID-19 infection. SARS-CoV-2 Prominently induces pulmonary and systemic injury with other synergistic mechanisms. Preexisting chronic inflammatory conditions markedly sustain and aggravate the severity and cytokine storm. Inflammatory responses are closely linked with COVID-19 severity …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy Read article
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Clone-Specific Drug Delivery Systems: Targeted Approaches and Future Clinical Applications
Abstract: Clone-specific drug delivery systems represent a transformative frontier in personalized medicine, addressing the longstanding challenge of clonal heterogeneity within diseases such as cancer, infectious diseases, and autoimmune disorders. Traditional drug delivery platforms often fail to discriminate between pathogenic and healthy cells, leading to systemic toxicity and reduced therapeutic efficacy. In contrast, clone-specific systems aim to selectively target and eliminate disease-driving cellular clones based on unique molecular signatures, thereby improving treatment …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 21–29 Read article
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Tinospora Cordifolia (Willd.) Hook.f. & Thomson: A Review on Herbal Formulations and Health Benefits
Abstract: India has a vast variety of medicinal plants utilised as natural medicines since prehistoric times. Herbal medicine was the main form of treatment earlier in the 20th century because neither antibiotics nor analgesics were readily available. Nowadays, natural plant products are becoming more significant in clinical research since they have no side effects and have greater pharmacological response than allopathic medications. Tinospora cordifolia (Giloy or Guduchi) is a climbing shrub …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 3, 2024 · pp. 14–19 Read article
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Nano‑Enabled CT for Cancer Imaging: From Molecular Targeting to Image‑Guided Therapy
Abstract: Nano‑enabled computed tomography (CT) exploits high‑atomic‑number (high‑Z) nanomaterials engineered with targeting ligands and therapeutic payloads to enhance contrast, enable molecular imaging, and support image‑guided interventions in oncology. Tumor‑specific nanoprobes such as RGD‑modified gold nanorods, polymer‑coated bismuth nanoparticles, and peptide, antibody, or aptamer‑functionalized platforms can intensify tumor conspicuity, allow early lesion detection and staging, and provide real‑time treatment monitoring. Integration of CT visibility with photothermal, photodynamic, chemo‑, radio‑, and immunotherapeutic functions …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 1, 2025 · pp. 40–49 Read article