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182 articles for “Formulation Optimization”
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Effect of Polymer Crosslinking on Drug Release Kinetics
Abstract: In order to improve treatment effectiveness and minimise adverse effects, polymer-based drug delivery systems are often used to produce regulated and sustained drug release. Polymer crosslinking, which alters the structural, mechanical, and degrading characteristics of the polymer matrix, is one of the key elements affecting drug release kinetics. The porosity, swelling behaviour, and rate of degradation of the polymer are all impacted by the crosslinking process, which may be accomplished …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 636–647 Read article
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Intuitionistic Fuzzy Hypergraph Laplacians and Dominating Transversals for Resilient Discrete Network Design
Abstract: This manuscript develops a discrete mathematical framework for resilience analysis on networks whose interactions are polyadic, uncertain, and partially conflicting. Classical graphs compress multi-way coordination into pairwise edges, while ordinary fuzzy graphs often ignore the non-membership information that becomes critical in emergency logistics, infrastructure interdependence, and cyberphysical coordination. We therefore formulate an intuitionistic fuzzy hypergraph in which each vertex hyperedge incidence carries membership, non-membership, and hesitation, and we construct a …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 13, Issue 2, 2026 · pp. 15–21 Read article
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A Research on Formulation and Evaluation of Clove Gel for Treatment of Scabies
Abstract: Scabies remains a pervasive global health issue, with a need for more effective topical treatments. This research focuses on the formulation and evaluation of a clove oil-based gel containing eugenol, the primary bioactive component, for the treatment of scabies. Eugenol’s well-documented antimicrobial, anti-inflammatory, and ant parasitic activities make it an ideal candidate for targeting Sarcoptes scabiei, the mite responsible for scabies. The formulation was prepared by incorporating clove oil and …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 3, 2024 · pp. 22–31 Read article
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Kinematic and Dynamic Modelling of a 6-DOF Robotic Manipulator for Industrial Applications
Abstract: The rapid evolution of industrial automation has intensified the need for highly accurate, flexible, and intelligent robotic systems capable of operating in dynamic and demanding environments. Among these systems, six-degree-of-freedom (6-DOF) robotic manipulators have emerged as a versatile solution due to their superior dexterity, large workspace, and human-arm-like motion capabilities. This research focuses on the comprehensive kinematic and dynamic modelling of a 6-DOF robotic manipulator designed for various industrial tasks …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 3, Issue 2, 2025 · pp. 27–32 Read article
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Critical Nutritional Needs of Infants: A Review of Challenges and Solutions in Infant Nutrition
Abstract: This review paper examines the critical nutritional needs of infants, focusing particularly on the growth and development of children aged 6-12 months. During this phase, infants experience rapid physical, cognitive, and emotional development, which is heavily dependent on adequate nutrition. The paper explores various aspects of infant nutrition, including the roles of essential nutrients, the challenges posed by malnutrition, and the specific implications of protein energy malnutrition (PEM). In addition, …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 14, Issue 1, 2025 · pp. 11–14 Read article
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Polymeric Drug Delivery Systems for Veterinary Applications
Abstract: Drug delivery systems play a pivotal role in veterinary medicine, facilitating the effective administration of medications to animals for therapeutic purposes. This review provides a comprehensive overview of the definition, importance, and recent advancements in drug delivery systems for veterinary applications. Beginning with an introduction to the challenges inherent in veterinary drug delivery, the review outlines the significance of innovative delivery systems in optimizing drug efficacy, enhancing patient compliance, and …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 1, 2024 · pp. 19–34 Read article
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Impact of Specially Prepared Food on Indian Big Carp Growth in West Bengal, India’s Cooch Behar District
Abstract: This four-year longitudinal study (2008–2012) in the Cooch Behar District of West Bengal, India, utilized on-farm ponds to evaluate the comparative growth performance of Indian Major Carps (IMCs) – Catla catla, Labeo rohita, and Cirrhinus mrigala – when subjected to four distinct supplementary feed formulations: fishmeal (A), soybean meal (B), silkworm pupae (C), and mustard oilcake (D). The experimental design contrasted treated ponds receiving formulated feed against control ponds relying …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 1, 2026 · pp. 7–12 Read article
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Fatigue Analysis of the FSAE Vehicle's Front Wheel Hub
Abstract: This study illustrates the design and analysis of the FSAE vehicle's front wheel hub. Because wheel hubs are subjected to cyclic loads on a continuous basis, there is a risk of fatigue, which leads to material failure. The start and spread of cracks in a material as a result of cyclic loading is known as fatigue. The brake discs could not be easily removed since the disc is positioned between …
Published in Journal of Automobile Engineering and Applications Read article
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Strategies for the Development and Optimization of Orally Disintegrating Tablets (ODTs) to Improve Bioavailability and Patient Compliance
Abstract: Background: Pharmaceutical scientists have developed Orally Disintegrating Tablets (ODTs) to advance patient drug acceptance and biological system availability through simplified medi-cation delivery especially for children and senior citizens and people who cannot swallow pills regularly. The oral disintegrating tablets dissolve in the mouth within thirty seconds or less (USP 701) while needing no additional liquid thus making them suitable for both emergency treatments. Objective: The research examines ODT development strategies …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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Gear-Related Stress Analysis and Comparison Between the Fem and Agma Standards
Abstract: In many different devices, gears enable the efficient transfer of motion and torque. They are an essential component of modern mechanical power transmission systems. It has been demonstrated that bending and surface contact stresses at the gear tooth are the primary causes of gear failure, despite their widespread use. Too much stress can lead to tooth wear, pitting, or breakage, which can ultimately reduce the operating life and reliability of …
Published in Trends in Mechanical Engineering & Technology · Vol. 15, Issue 3, 2025 · pp. 13–18 Read article
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Enhancing Mechanical and Durability Performance of Composite Material Using Egg Shell Powder and Copper Slag.
Abstract: This research aims to investigate the use of copper slag (CS) and Egg Shell Powder (ESP) as partial substitutes in polymer composite to enhance mechanical properties and durability. Considering that the construction sector is recognized for consuming a significant amount of resources in comparison to other industries, its further expansion poses a direct danger to resource availability. This could disrupt ecosystems, lower biodiversity, and have an effect on riverine and …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 1–7 Read article
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The Silent Mineral: Structural Complexity and Industrial Utility of Natural Kaolin
Abstract: Kaolin, a naturally occurring aluminosilicate clay predominantly comprising the mineral kaolinite (Al₂Si₂O₅(OH)₄), exhibits a 1:1 layered silicate structure that imparts distinctive physicochemical properties suitable for extensive industrial utilization. Deposits of kaolin are broadly classified into primary (residual) and secondary (sedimentary) categories, each defined by their geological origin and mineralogical features. The industrial processing of kaolin encompasses stages such as raw material extraction, beneficiation, and purification, aiming to optimize parameters including …
Published in International Journal of Crystalline Materials · Vol. 2, Issue 1, 2025 · pp. 52–61 Read article
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Evaluation of Polyethylene Glycol (PEG)-Based Polymers for Improving Solubility and Bioavailability of Poorly Soluble Drugs
Abstract: A significant barrier to optimizing oral bioavailability is the inadequate water solubility of numerous pharmaceutical compounds. This study examined whether polymer systems utilizing polyethylene glycol (PEG) may enhance the solubility and bioavailability of a poorly soluble model drug. Multiple PEG polymers with molecular weights between 2,000 and 10,000 Da were utilized to produce PEGylated preparations. The formulations were subsequently evaluated for dissolution efficacy, medication loading capacity, particle size, and solubility …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 489–499 Read article
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A Review of Different Polymer and Plasticizers
Abstract: Plasticizer and polymer are essential components in the pharmaceutical industry, especially when creating both cutting-edge and conventional drug delivery systems. The differences between synthetic, semi-synthetic, and all-natural polymers are examined in this review to highlight their diverse qualities and uses. When designing drug delivery systems to target areas, the choice of polymer is crucial. Because of their repeatability and adaptability, synthetic polymers are widely used in the creation of precision …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 1–7 Read article
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Collaborative Robotics and Smart Automation: Enhancing Human–Robot Synergy in Industry 5.0
Abstract: Industry 5.0 marks a paradigm shift from efficiency-centric automation to a human-centred, sustainable, and collaborative production environment . In this context, collaborative robots, commonly referred to as cobots, play a central role by enabling direct and safe interaction between humans and machines within shared workspaces. These systems are designed to support human operators by undertaking repetitive, precision-intensive, and physically demanding tasks, thereby allowing humans to focus on supervisory control, problem-solving, …
Published in International Journal of Advanced Robotics and Automation Technology · Vol. 4, Issue 1, 2026 · pp. 22–29 Read article
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Parametric Investigations of Melt Flow Index for Nylon6-Mica Composite Based Hybrid FDM Filament
Abstract: The development of new hybrid filaments with improved mechanical and thermal properties has been driven by the increasing need for high-performance materials in additive manufacturing. This study explores the parametric investigations of the Melt Flow Index (MFI) for Nylon6-Mica composite-based hybrid Fused Deposition Modeling (FDM) filament. The investigation uses the Taguchi technique to examine how different extrusion temperatures, loads and the percentage of Mica filler affect the MFI, a critical …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 165–173 Read article
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Exploring the Intersection of AI Network Pharmacology and Ayurveda: Innovations in Traditional Medicine
Abstract: Integrative frameworks that integrate traditional medicine and modern computer research are increasingly important for advancing evidence-based, individualized healthcare. One interesting strategy is the combination of Ayurveda, network pharmacology, and artificial intelligence (AI). AI expands the capability by allowing for the quick analysis of biomedical big data, the identification of therapeutic trends, and the optimization of treatment plans. Ayurveda, with its long-standing emphasis on individualized care, holistic balance, and natural remedies, …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 92–98 Read article
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Formulation Development and In Vitro Evaluations of Trimetazidine and Clopidogrel Bilayered Tablets
Abstract: The Bilayered tablets consisting of Trimetazidine SR as well as Clopidogrel IR were efficiently prepared by damp granulation technique as well as straight compression approach specifically. The prepared powdered mix (SR) were also preserved the physiochemical residential or commercial properties of tablet computers such as thickness, firmness, weight variant, friability and drug material. The enhanced formula consists of the average thickness of 3.1 ± 0.034, average firmness of 4.2 ± …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 8, Issue 3, 2023 · pp. 29–40 Read article
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Natural Cooling Agent: Utilizing Menthol as a Paraben-Free Preservative in Herbal Cosmetics
Abstract: The quest for natural and sustainable alternatives in cosmetic products has intensified, driving the search for effective natural preservatives. Menthol, derived from mint plants, is being recognized for its cooling properties and potential as a paraben-free preservative. This study investigates menthol’s efficacy as a preservative in herbal cosmetics, addressing consumer concerns about synthetic preservatives while ensuring product safety and longevity. This research examines menthol’s antimicrobial effects on common cosmetic contaminants …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 3, 2024 · pp. 16–39 Read article
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Integrating Biotechnology, Physiology, and Agroecological Practices for Sustainable Crop Production and Protection
Abstract: Global agriculture is currently confronting a wide range of complex challenges, including a rapidly growing population, climate change, increasing pest and disease pressures, soil degradation, water scarcity, and the urgent need for sustainable intensification of crop production. Addressing these issues requires integrated strategies that combine crop improvement (through modern breeding and biotechnology), precision agronomic practices related to soil, irrigation, and nutrition, as well as advancements in plant physiology, molecular biology, …
Published in International Journal of Trends in Horticulture · Vol. 2, Issue 2, 2025 · pp. 1–6 Read article