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249 articles for “Active safety”
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A Systematic Review of Impurity Profiling and Stability Studies in Pharmaceutical Drug Substances
Abstract: Ensuring the safety, efficacy, and quality of pharmaceutical goods is essential in the Indian pharmaceutical market, which is a global centre for generic drugs. Stability studies and impurity profiling are two fundamental activities that ensure this quality during the whole lifespan of a medicine. The effect of environmental variables such as temperature, humidity, and light on the quality of a drug substance over time is demonstrated by stability studies. The …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 81–88 Read article
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Review article on Quality Control in Clinical Trials
Abstract: Quality control (QC) is a critical component in the conduct of clinical trials, ensuring the accuracy, reliability, and credibility of data collected throughout the study. It encompasses a systematic set of procedures designed to monitor trial conduct and data integrity, thus safeguarding the rights, safety, and well-being of participants. This review explores the principles, implementation, and evolving practices of quality control in clinical trials, highlighting its importance across all phases …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 01–07 Read article
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Adverse Drug Reactions and Pharmacovigilance of Herbal Medicines in India
Abstract: The use of ayurvedic medicines is popular in India and in recent times has become accepted in other countries. Associated with this increasing use, are growing concerns about the safety of ayurvedic medicines. This paper discusses in brief the ayurvedic concepts of adverse reactions to medicines, the need for pharmacovigilance of ayurvedic medicines, challenges in introducing pharmacovigilance in ayurveda and some recommendations to successfully implement these activities. Pharmacovigilance is the …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 5, Issue 1, 2016 · pp. 10–13 Read article
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The Clinical Landscape of Wogonin: Advancing Targeted Treatments for Chronic Diseases
Abstract: The traditional Chinese medicinal herb Scutellaria baicalensis Georgi, commonly known as Chinese skullcap or Huang-Qin, has long been used to treat a variety of conditions, including cancer, viral infections, and seizures. Its pharmacological effects are largely attributed to the high concentration of flavones, particularly wogonoside, and its aglycone derivative, wogonin. Among the bioactive compounds found in S. baicalensis, wogonin has garnered the most scientific attention due to its potent therapeutic …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 46–52 Read article
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Analysis of the Impact of Seabed Earthquakes on Coastal Structures and Foundation Design
Abstract: Earthquakes in the seabed occur with varying magnitudes. Seabed earthquakes cause a rapid rise in water levels, which can lead to flooding and structural damage. Therefore, when designing buildings near the seashore, it is essential to account for the additional load on columns due to water thrust. Earthquakes occurring at the seabed generate intense ground acceleration of varying magnitudes, significantly affecting water levels and inducing destructive flooding along coastal regions. …
Published in Journal of Offshore Structure and Technology · Vol. 12, Issue 3, 2025 · pp. 42–49 Read article
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Arduino based LPG Gas Leakage smart Detection system
Abstract: Leaking LPG can result in significant mishaps even though it a common fuel for both residential and commercial activity. In this study, a microcontroller with a MQ2 gas sensor, buzzer, and GSM module is used to detect LPG leaks. Upon early detection of leakage, the wireless system can initiate automatic safety actions and send SMS warnings and sound alarms. The design and implementation of a microcontroller-based LPG leak detection and …
Published in Journal of Microcontroller Engineering and Applications · Vol. 13, Issue 1, 2026 · pp. 1–10 Read article
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Smart Charging Station
Abstract: Wireless charging is a revolutionary technology that transfers power to electrical devices across an air gap, eliminating the need for tangled cords. It has become increasingly popular due to its convenience and effectiveness in powering gadgets. However, integrating wireless charging with current wireless communication technologies poses scheduling, power management, and technological challenges. Researchers are actively working on integrating wireless charging into various devices to meet the growing demand for this …
Published in Research & Reviews: A Journal of Embedded System & Applications · Vol. 12, Issue 2, 2024 · pp. 1–6 Read article
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Safety and Efficiently Management Through Alternative Medicine (Yoga and Naturopathy) Lifestyle in Patients Suffering from Cervical Spondylosis
Abstract: Cervical spondylosis (CS) is generally explained as the degeneration and age-related condition or state of affecting joints of the neck. It is also known as cervical osteoporosis. This situation or symptoms is usually found in men and women at the age of 40 years or above. The aim of the study focuses on reduction of symptoms and increase in functional activities of elderly patients with spondylosis before and after modalities …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 4, Issue 3, 2017 · pp. 11–22 Read article
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Influence of Antibiotic Promotion Practices on Pharmacovigilance and Resistance Reporting Patterns
Abstract: The global escalation of antimicrobial resistance (AMR) has emerged as a critical public health crisis, undermining decades of therapeutic advancements. While inappropriate prescribing and misuse of antibiotics are widely acknowledged contributors, the role of pharmaceutical promotion practices remains underexplored in influencing prescribing behaviors and downstream pharmacovigilance systems. This review critically examines how antibiotic promotion strategies – ranging from direct physician engagement to digital marketing – affect adverse drug reaction (ADR) …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 1–11 Read article
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A Comparative Study Between GSM and CNN to Develop Gesture Detection Based Alert System for Women Safety
Abstract: Women’s safety is a pressing issue in today’s world, and technology can play a crucial role in addressing it. This project introduces a facial expression recognition device that uses Convolution Neural Network (CNN) technology and develop it’s comparison with an expression system with use of GSM is done. Unlike traditional methods relying on manual activation or dedicated devices, this system reacts instantly to threatening situations by recognizing predefined gestures, ensuring …
Published in International Journal of Electrical Power and Machine Systems · Vol. 2, Issue 1, 2024 · pp. 24–30 Read article
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Polymeric Materials in Drug Delivery: Applications in Topical Formulations
Abstract: Polymeric materials play a crucial role in modern drug delivery systems, particularly in topical formulations. These materials enhance drug stability, control release rates, and improve bioavailability, making them essential components in pharmaceutical advancements. Polymers such as chitosan, hydrogels, and emulsifying agents are widely utilized in immediate-release topical formulations, where they contribute to improving therapeutic efficacy by ensuring uniform drug distribution, increased solubility, and enhanced skin penetration. The integration of polymer-based …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 34–41 Read article
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Artificial Intelligence Based Portable Robot Device for Autonomous Venepuncture
Abstract: Venepuncture is a source of medical hurt and is necessary for a wide range of therapeutic procedures. Venpuncture-related complications worsen in difficult settings, where the success rate is largely dependent on the physiology of the patient and the skill of the practitioner. It is difficult to find the vein for infants, adolescent girls, obese and elderly people and it is causing severe pain in the traditional manual blood drawing system. …
Published in International Journal of Advanced Robotics and Automation Technology · Vol. 2, Issue 1, 2024 · pp. 35–38 Read article
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VIGILENS-An Innovative Anti Sleep and Alert System
Abstract: This project aims to create an advanced Anti-Sleep Alarm System meticulously crafted to detect and mitigate the dangers of driver fatigue in real-time. Designed with a keen focus on both effectiveness and ease of implementation, Vigilens offers a comprehensive approach to enhancing road safety for all. Central to Vigilens is its utilization of cutting-edge technology housed within a pair of specially engineered goggles. These goggles are equipped with a sophisticated …
Published in Recent Trends in Sensor Research & Technology · Vol. 10, Issue 3, 2023 · pp. 19–28 Read article
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IoT-Enabled Multi-Sensor Accident Detection and Automatic Rescue Alert System
Abstract: Road accidents and vehicle instability caused by skidding, engine overheating, and improper braking behavior remain major concerns in modern transportation systems. This project presents an intelligent vehicle safety and accident detection system that integrates multiple sensors and control logic to enhance driving safety and reduce accident severity. A vibration sensor is employed to detect collision or impact events and accurately identify vehicle accidents. An accelerometer sensor is used for real-time …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 4, Issue 1, 2026 · pp. 9–19 Read article
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CB₁ Reverse Agonists: A Cheminformatic and Patent Landscape Study
Abstract: The endocannabinoid system plays a crucial role in numerous physiological functions, making cannabinoid receptor 1 (CB1) an attractive target for therapeutic development. This review provides a systematic analysis of patent filings from 2019 to 2023 that focus on small-molecule CB1 reverse agonists. It begins with an overview of the endocannabinoid system, highlighting CB1’s involvement in energy balance, pain regulation, and neuroinflammatory processes The main section of the review examines fifteen …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 33–36 Read article
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Novel 1,3,4-Thiadiazole Derivatives: Design, Synthesis, Characterization and Anticancer Evaluation – A Review
Abstract: Cancer remains one of the leading causes of mortality worldwide despite significant advances in diagnosis and treatment. The clinical usefulness of many anticancer drugs is often restricted by toxicity, poor selectivity, and the emergence of drug resistance. These limitations have encouraged the search for novel heterocyclic compounds with improved therapeutic efficacy and safety. Among these, the 1,3,4-thiadiazole scaffold has gained considerable attention because of its favorable physicochemical characteristics, metabolic stability, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 42–49 Read article
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CRISPR-Based Enhancement of Secondary Metabolites in Artemisia annua: Focus on Artemisinin Biosynthesis
Abstract: Medicinal plants are natural biofactories producing secondary metabolites with significant therapeutic value, including terpenoids, alkaloids, and phenolics. Among these, artemisinin, a sesquiterpene lactone from Artemisia annua L. is the cornerstone of global antimalarial therapy along with additional anticancer, antiviral, and antimicrobial activities. However, artemisinin content in the native plants is inherently low (typically 0.01–0.8% dry weight), restricting affordable and consistent supply. Conventional approaches to increase production include classical breeding, singlegene …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 2, 2026 · pp. 23–35 Read article
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Simulation-Based Training in Nursing Education: An Academic Perspective
Abstract: Simulation-based education has become an important component of contemporary nursing education, providing students with opportunities to develop clinical competence, critical thinking, decision-making, and patient safety skills in a controlled learning environment. By recreating realistic clinical situations, simulation allows nursing students to apply theoretical knowledge, practice clinical procedures, and respond to patient care challenges without exposing actual patients to unnecessary risks. Different simulation approaches, including high- and low-fidelity manikins, standardized patients, …
Published in Journal of Nursing Science & Practice · Vol. 16, Issue 2, 2026 · pp. 42–47 Read article
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Evaluation of the anti diabetic effects of ethanolic root extract from polyalthania longifora in diabetic rats induced by streptozotin and nicotinamide with considaertion of toxocological aspects
Abstract: The root of Polialthia Longifolia was selected for the evaluation of antidiabetic potential in STZ-nicotinamide induced diabetic rat model.The root extract was extracted by hot percolation using ethanol as a solvent in soxhlet apparatus and the preliminary phytochemical screening was performed and it shows that the ethanolic root extract of Polialthia Longifolia contains alkaloids, glycosides, flavonoids and tannins. Safety profile is essential for the drugs obtained from the plant origin. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 37–50 Read article
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Microsphere and Nanoparticle Drug Delivery Systems: Role of Polymers in Pharmacology
Abstract: Microsphere and nanoscale drug delivery methods have changed the field of pharmacology by making treatment agents more bioavailable, more targeted, and easier to manage. These delivery systems, which are mostly made up of polymers, look like a good way to get around the problems that traditional drug formulations have, like not dissolving well, clearing quickly, and spreading in different places. Plastics are very important in the creation of these improved …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 420–432 Read article