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1938 articles for “UTS”
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Molecular Pharmacokinetics and Structural Docking of Phenolic Acids for Targeting NF-κB Pathway Components in Inflammation and Fibrosis: A Computational Approach Toward Therapeutic Discovery
Abstract: Inflammation and Fibrosis are critical pathological processes associated with various chronic diseases, often mediated by the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway. This study investigates the therapeutic potential of phenolic acids as modulators of the NF-κB pathway, aiming to identify novel ligands that can effectively interact with key components of this signaling cascade. A comprehensive computational approach was employed, utilizing molecular docking, pharmacological screening, and post-docking …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 14–31 Read article
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Light-Dark Cycle Disruption in Hypothalamus Tissue of Mus Musculus Causes Change in the Expression of Gm45928 Gene
Abstract: The majority of organisms on earth display consistent 24-hour rhythms in their physiology and behavior due to circadian biology. Light and dark cycles play a key role in setting our internal body clock, which controls things like our sleep patterns, hormone levels, body temperature, and metabolism. The disruption of the light-dark cycle has significant effects on the molecular and behavioral rhythms of the circadian clock of hypothalamus. Gm45928 is a …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 32–46 Read article
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Optimizing Data Processing Efficiency in Big Data: Advanced MapReduce Algorithm Innovations
Abstract: The exponential growth of big data in recent years has created an urgent need for innovative and efficient processing frameworks capable of managing and analyzing massive and complex datasets. Among these, MapReduce has gained prominence as a powerful tool for distributed data processing due to its simplicity and scalability. However, traditional MapReduce frameworks often encounter significant limitations in terms of efficiency, scalability, and resource optimization, particularly when handling large-scale and …
Published in International Journal of Data Structure Studies · Vol. 3, Issue 1, 2025 · pp. 1–7 Read article
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Multi-Screen Interface Applications in Graphical User Interface for Ornamental Efficiency in Computer Programming
Abstract: Use of multi-screen interfaces for graphical user interfaces (GUIs) has transformed the way we do computer programming by improving the speed, efficiency and usability. Also, these interfaces help programmers multitask easily by decoupling the different functionalities, code debugging, and data visualization in real-time through multiple terminals which cuts down context switching, thus maintaining workflow organization. Multi-screen GUI applications enable developers to organize their workspace and work efficiently, with customized or …
Published in International Journal of Computer Science Languages · Vol. 3, Issue 1, 2025 · pp. 27–31 Read article
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Zika Virus: Long-term Effects and Vaccine Development Efforts
Abstract: Zika virus (ZIKV) is a mosquito-borne flavivirus that gained international concern following the 2015-2016 outbreak in the Americas. Although most ZIKV infections are asymptomatic or mild, the virus presents significant public health risks due to its ability to cause severe neurological complications, especially in pregnant women and their offspring.Congenital Zika Syndrome (CZS) encompasses a range of fetal abnormalities, including microcephaly, vision impairment, hearing loss, and developmental delays. Infants exposed to …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 25–28 Read article
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Screening of Newer Phytoconstituents on Novel Enzymes for their Biological Activity
Abstract: Background: Hyperlipidemia and gout are prevalent metabolic disorders significantly impacting global health. The xanthine oxidase and HMG-CoA reductase pathways play pivotal roles in the pathophysiology of these conditions. This study explores the potential of natural phytoconstituents—daidzein, resveratrol, and genistein—as dual inhibitors for these enzymatic targets, offering insights into innovative therapeutic strategies. Aim: To evaluate the potential of natural phytoconstituents—daidzein, resveratrol, and genistein—as dual inhibitors of xanthine oxidase and HMG-CoA reductase …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 81–86 Read article
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Solid Lipid Nanoparticles in Medicine: Formulation, Characterization and Future prospects
Abstract: An alternative to conventional colloidal carriers such liposomes, polymeric nanoparticles, and emulsions, solid lipid nanoparticles (SLNs) were created in the early 1990s. Benefits include targeted medicine distribution, controlled drug release, and improved stability. An extensive review of the excipients utilized, the production techniques, including the membrane contractor approach, and the possible advantages and disadvantages of SLNs is given in this work. It investigates secondary stabilization techniques like freeze-drying and spray-drying, …
Published in International Journal of Membranes · Vol. 2, Issue 1, 2025 · pp. 1–15 Read article
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Advancements In Metal-Fiber Composites for Aerospace and Defense Applications: A Comprehensive Review
Abstract: This paper provides a comprehensive review of fiber-reinforced composites, focusing specifically on the utilization of metal-fiber composites in aerospace such as metal surface preparation prior to bonding, resin selection, and detailed examination of mechanical testing and impact studies. The significance of metal surface preparation for establishing strong bonding, which is a crucial initial step in composite fabrication, is discussed. Additionally, the prevalent use of epoxy resins and their importance in …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 96–108 Read article
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Assessment of Differential Global Positioning System (DGPS Technology for Generating Accurate Topographic Maps and Controls: A Case Study of Farin-Lamba to Kwali College Area
Abstract: This study investigates the application of Differential Global Positioning System (DGPS) for topographic mapping and control point establishment in Farin-Lamba to Kwali College Area. The second order Survey controls extension are critical indices for ensuring structural and border control mechanisms in environmental development projects. However, creating these controls using traditional ways presents major obstacles. Most modern techniques are improvements on ancient approaches, which raises the possibility of environmental dangers and …
Published in International Journal of Land · Vol. 2, Issue 1, 2025 · pp. 11–23 Read article
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Literature Review On Nanotechnology In Dentistry
Abstract: Nanotechnology is a relatively new field in dentistry that utilizes nanomaterials, nanorobots, and nanotechnology for diagnosing, treating, and preventing dental diseases. Nanotechnology has revolutionized various fields of dentistry, offering innovative solutions that enhance patient care, improve treatment outcomes, and contribute to the overall advancement of dental science. This cutting-edge technology has found applications in several areas, including restorative dentistry, dental implants, early cancer diagnosis, dental hypersensitivity, and pain management, among …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 2, 2025 · pp. 19–23 Read article
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Advance Surveillance System Integrated with Weapon Detection and Accident Detection
Abstract: Security concerns have become paramount as there is rise in crime rates in crowded events and isolated areas. Abnormal event detection and monitoring system, utilizing computer vision, are crucial for tackling these challenges. In parallel, reducing mortality rates from accidents by ensuring timely emergency response in essential. This study presents the implementation of automatic weapon detection and accident detection. In weapon detection, YOLO v4, Convolutional Neural Networks (CNN), and Faster …
Published in Research & Reviews: A Journal of Embedded System & Applications · Vol. 13, Issue 1, 2025 · pp. 47–54 Read article
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A Review of Analytical Method Development and Validation of Amiodarone Pharmaceutical Dosage Form
Abstract: The review provides an in-depth analysis of the analytical method development and validation process for amiodarone tablets. Method validation is crucial in the pharmaceutical industry for ensuring the quality and efficacy of tablets, as it ensures the accuracy, precision, and reliability of analytical techniques used in drug testing. It is a prerequisite for method development, adhering to good manufacturing practices, and optimizing processes. This review aims to consolidate and analyse …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 59–71 Read article
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Breaking the Cycle: The Impact of Hygiene Deficiencies on the Health of the Poor
Abstract: Poor sanitation and hygiene present significant health risks, particularly for individuals in low- income communities. Inadequate sanitation systems increase the likelihood of exposure to harmful microorganisms found in contaminated water, food, and environments. This exposure contributes to the spread of waterborne diseases such as cholera, dysentery, and typhoid, along with various gastrointestinal illnesses. Limited access to clean water and soap for handwashing exacerbates these risks, particularly for children, who are …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 22–39 Read article
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Shell Programming in Computer Programming: Application and Techniques
Abstract: Shell programming is writing scripts with shell commands to automate tasks in an OS. Well, the shell is what enables users to reach the kernel, the program that controls the kernel, which actually enables the users to execute commands, manage files and run processes efficiently. The examples are Bourne Shell (Sh), Bourne Again Shell (Bash), Korn Shell (Ksh), C Shell (Csh), Z Shell (Zsh), etc. Of these, Bash is the …
Published in Journal of Advances in Shell Programming · Vol. 12, Issue 1, 2025 · pp. 17–21 Read article
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Influence of Nanomaterial on Biofuel Extracted from Lemon Seed Feedstock
Abstract: Biodiesel, which is a type of biofuel, offers a replacement to the traditional diesel fuel currently available on the market, which is derived from petroleum that is both more sustainable for the environment and more attractive from an economic standpoint. A plethora of environmental benefits can be obtained through the utilization of this technology, including a reduction in emissions of greenhouse gases and particulate matter, as well as the possibility …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 200–210 Read article
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Assessing Thyroid Disorder Awareness Among Pregnant Women: A Hospital-based Study in Kottayam
Abstract: The current study was carried out at Caritas Hospital to evaluate the knowledge of pregnant women regarding thyroid disorders. The study aimed to assess the level of knowledge about thyroid disorders among pregnant women and to explore the relationship between knowledge levels and selected demographic factors. A total of 194 pregnant women attending the obstetrics and gynecology outpatient department at Caritas Hospital in Kottayam were included using a convenience sampling …
Published in International Journal of Community Health Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 16–22 Read article
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A Critical Review on Carbon Fiber Reinforcement in Various Applications
Abstract: Carbon fiber, celebrated for its outstanding mechanical properties and impressive strength-to-weight ratio, has become a critical material in various industries. This review journal, An In-Depth Study of Carbon Fiber Reinforcement in Diverse Applications, delves into the recent advancements and innovations in carbon fiber technology. The exploration includes its integration into aerospace, automotive, civil engineering, sports equipment, and renewable energy sectors. The aerospace industry leverages carbon fiber for constructing lightweight, fuel-efficient …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 490–502 Read article
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Mechanical Testing Under Tensile-load
Abstract: Mechanical testing is a technique used to establish a material's mechanical qualities by examining its strength, toughness, hardness, and other characteristics. Specimens produced of various materials whose qualities need to be examined are used to verify this property. In which a static load is applied and a dynamic load is applied, and the test is completed. Understating loads in mechanical testing is the topic of this research article. Any manufacturing …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 3, Issue 1, 2025 · pp. 1–10 Read article
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An Insightful Study on SMEDDS Challenges and Potential Strategies
Abstract: Self-microemulsifying drug delivery systems (SMEDDS) have gained attention as an effective approach to enhance the bioavailability of poorly water-soluble drugs. They are innovative lipid-based formulations designed to enhance the solubility, bioavailability, and therapeutic efficacy of poorly water-soluble drugs. The development of SMEDDS involves systematic selection of components based on solubility and emulsification efficiency, followed by optimization of ratios using pseudo-ternary phase diagrams. The resulting formulations are evaluated for droplet size, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 311–334 Read article
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Reconfigurable AES Based AEAD For Multi-Mode Operation with Lightweight Compatibility
Abstract: The proposal is for a lightweight, multi-mode, reconfigurable authenticated encryption system with associated data (AEADs) based on AES. It is challenging to effectively integrate different AEADs in hardware because each one has its own mode of operation and/or subfunctions, even though some major AEADs share several basic components (such as the XOR-Encryption-XOR (XEX) scheme, block chaining, and advanced encryption standard (AES). This paper proposes hardware that effectively combines the basic …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 3, Issue 1, 2025 · pp. 54–68 Read article