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1962 articles for “IDS” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Targeting PTPN22 in Arthritis: Molecular Docking and Pharmacokinetic Evaluation of Artemisia vestita Compounds
Abstract: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by inflammation of the synovial membrane, commonly resulting in swelling, pain, stiffness, and overall fatigue. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been identified as a risk factor linked to various autoimmune diseases, including RA. In the PTPN22 gene, two missense Single nucleotide polymorphisms (SNPs) are associated with autoimmune conditions. The R620W (C1858T, rs247660) variant in exon 14 has been …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 20–31 Read article
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Molecular Docking of Arjuna Tree Phytocompounds for Ischemic Heart Disease
Abstract: Heart disease is a serious condition that can be caused by several lifestyle changes and sometimes genetic problems. The primary protein component of apolipoprotein is the LDL receptor, which indicates that a reduction in LDL levels can reduce the risk of ischemic heart disease. Apolipoprotein levels are associated with increased levels of ischemic heart disease. Using ADMET analysis, drug likelihood prediction, and molecular docking, this work attempted to find natural …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 42–52 Read article
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Biomarkers in Cancer Research: Discovery and Future Directions
Abstract: Biomarkers have transformed the study of cancer, providing critical information regarding prognosis and therapy response and promoting earlier diagnosis. This paper discusses the different parts of cancer biomarkers, starting with their description, classification, and major types, which are the groundwork for understanding their clinical role. The discussion on the development and validation process of biomarkers is then undertaken, focusing on state-of-the-art techniques and the importance of ensuring accuracy and reproducibility. …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 22–26 Read article
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Detection of Phishing Website Using URL
Abstract: Phishing attacks are one of the greatest threats to online security, where fraud websites deceive users into giving out sensitive information. Traditional methods of detection, such as blacklists and heuristic-based systems, often fail in identifying newly created or sophisticated phishing websites. This study proposes an intelligent phishing website detection system using Convolutional Neural Networks (CNNs) in analyzing URLs and associated features. Using labeled URLs, the system employs such attributes such …
Published in Journal Of Network security · Vol. 13, Issue 1, 2025 · pp. 10–15 Read article
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Real-time DDoS Attack Prediction in SDN Environments Using Machine Learning
Abstract: The ever-growing reliance on sdn-based services necessitates robust security measures against Distributed Denial-of-Service (DDoS) attacks that threaten service availability. This project investigates the development of a real-time prediction system for DDoS attacks in sdn environments, leveraging the power of machine learning. The proposed system employs a Decision Tree classification algorithm implemented in Python. To ensure accurate attack identification, the system meticulously addresses data preprocessing challenges inherent in network traffic datasets. …
Published in Journal Of Network security · Vol. 13, Issue 1, 2025 · pp. 16–27 Read article
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The Issues for Introducing Green Hydro-electricity and Electric Vehicles in Transport: Energy Sector of South Asian Region
Abstract: The rapidly developing South Asian region has immense potential of amassing huge personal car population in upcoming years requiring supply of vast amount of fossil fuel whereas this region has no sizable fossil fuel reserve. This paper investigates the potential of hydro-electricity generation from Nepal and Bhutan areas of the region, electric vehicle introduction in increasing proportion for changing the course of unsustainable transport-energy trend in this region and achieving …
Published in Trends in Transport Engineering and Applications · Vol. 11, Issue 3, 2024 · pp. 1–13 Read article
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Enhancing Bituminous Mixes with Recycled Polyethylene: Performance Analysis Using Marshall Stability Test
Abstract: This study investigates the impact of incorporating recycled low-density polyethylene (LDPE) and high-density polyethylene (HDPE) in bituminous mixes for potential use in flexible pavement construction. Utilizing a Marshall Stability Test, various proportions of LDPE and HDPE were analyzed to determine optimal stability and flow characteristics. The test maintained a fixed Zycotherm content at 1.5% and varied LDPE content from 2% to 5% by weight, while HDPE content was also tested …
Published in Recent Trends in Civil Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 1–5 Read article
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Mathematical Models of Agricultural Cycles in Tribal Astronomy
Abstract: This paper delves into the intricate connection between traditional tribal agricultural practices and astronomical observations, showcasing how indigenous communities have historically relied on celestial movements to guide essential farming activities. By observing the phases of the moon, solar cycles, and the positions of star constellations, tribes have developed precise methods for determining the optimal timing for planting, harvesting, and seasonal planning. These astronomical practices are deeply embedded in their cultural …
Published in Research & Reviews : Journal of Statistics · Vol. 13, Issue 3, 2024 Read article
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Pharma Tech: Leveraging Software for Drug Development & Clinical Research
Abstract: The pharmaceutical sector is progressively adopting software solutions to enhance the drug development process and optimize clinical research results. Drug development is a time-consuming, expensive, and intricate process that traditionally requires extensive laboratory research, preclinical testing, and several stages of clinical trials. Software tools are revolutionizing these stages by improving efficiency, minimizing errors, and speeding up timelines. During preclinical testing, predictive software tools are used to model toxicological effects and …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 11–19 Read article
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Genomic Medicine Revolutionizes Heart Care: A New Standard of Practice
Abstract: The integration of genomic and precision medicine into cardiovascular healthcare represents a transformative advancement in addressing the global burden of cardiovascular diseases (CVDs). Precision medicine leverages genomic, proteomic, and metabolomic data to provide personalized care, optimizing treatment outcomes while minimizing adverse effects. Over the past decade, extensive research has highlighted its potential to revolutionize the management of major CVDs, including myocardial infarction, hypertension, and heart failure, which significantly contribute to …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 30–37 Read article
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The Art of Drug Design and Process Chemistry
Abstract: The creation of safe and efficient medications depends heavily on the art of drug design and process chemistry. This multidisciplinary discipline designs and optimizes drug candidates for therapeutic uses by fusing the concepts of biology, chemistry, and engineering. Researchers can develop compounds with pharmacological activity by using logical drug design techniques if they have a thorough understanding of the molecular targets implicated in disease pathways. By making it easier to …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 1–10 Read article
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Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
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Optimized Rectangular Microstrip Patch Antenna for Wireless Communications
Abstract: The design is for a microstrip patch antenna that is rectangular. The wireless local area network [WLAN] resonance frequency of the suggested antenna is 2.4GHz. The antenna's frequency selection has made it ideal for use in wireless local area networks, or WLANs. The antenna design is optimised using the optometric feature of the High Frequency Structure Simulator software (HFSS) to increase the accuracy and efficiency of the suggested antenna. HFSS …
Published in Journal of Telecommunication, Switching Systems and Networks · Vol. 12, Issue 1, 2025 · pp. 37–47 Read article
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The Future is Smelling: Exploring the Potential of e-Nose
Abstract: The human sense of smell, a complex and often underestimated faculty, allows us to perceive the world through volatile organic compounds (VOCs). This ability to detect and differentiate between aromas, flavors, and even potential hazards has inspired the development of the electronic nose, or e-nose. More than just a novelty, e-noses are rapidly becoming sophisticated analytical tools with applications that span across numerous industries. By mimicking the biological processes of …
Published in Journal of Semiconductor Devices and Circuits · Vol. 12, Issue 1, 2025 · pp. 15–25 Read article
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Exploring Technologies for Extractive Text Summarization: A Review of Transformer and Reinforcement Learning Models
Abstract: In recent years, the size of information on the Internet has increased exponentially. Therefore, a solution is needed to transform large amounts of raw data into useful information the human brain can understand. Automatic Text Summarization (ATS) is a part of Natural Language Processing (NLP) that aims to take long texts and shorten them, keeping the most important information in a clear and easy-to-understand way. This research report explores methods …
Published in Current Trends in Signal Processing · Vol. 15, Issue 1, 2025 · pp. 1–6 Read article
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Voltage Vigilance: Ensuring Balance and curbing Theft in Power Distribution Networks
Abstract: This project proposes a system for detecting electrical overload and earth faults using an Arduino Uno controller. The system uses a current sensor to identify overloads and a voltage sensor to detect earth faults. An ESP8266 module allows users to switch between the two fault detection modes. When an overload is detected, the Arduino turns off AC bulbs using a relay and sends an alert message via a GSM module. …
Published in International Journal of Advanced Control and System Engineering · Vol. 3, Issue 1, 2025 · pp. 15–21 Read article
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Plant-Derived Fiber-Reinforced Polymer Composites: The Impact of Compatibilizer on the Fundamental Characteristics and Degradation Properties
Abstract: By using compression molding, unidirectional polypropylene (PP) composites reinforced with banana fiber were created both with and without the use of stearic acid (SA) as a coupling agent. Four filler loading levels (10%, 20%, 30%, and 40% by weight) were employed during the composite manufacturing process, using raw banana fiber. The resulting composites underwent mechanical testing (tensile, bending, and impact characteristics). The ideal combination of mechanical properties was found in …
Published in Journal of Materials & Metallurgical Engineering · Vol. 15, Issue 1, 2025 · pp. 27–37 Read article
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Milk Allergy: Significance, Detection and Management
Abstract: Milk allergy is a significant public health issue, particularly among infants and young children, with prevalence rates between 2 and 6% in early childhood, declining to 0.1–0.5% in adulthood. It is an immune-mediated adverse reaction to milk proteins, primarily involving immunoglobulin E (IgE)-mediated responses. Symptoms range from gastrointestinal distress and respiratory complications to severe anaphylaxis. The etiology of milk allergy involves genetic predisposition, environmental factors, an immature immune system, and …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 14, Issue 1, 2025 · pp. 15–19 Read article
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Enhancing Mechanical Properties by Parameter Optimization in Fiber and Particle Reinforced Composites
Abstract: This research focuses on optimizing the mechanical and thermal properties of hybrid fiber and particle-reinforced composites through systematic parameter optimization using the Taguchi method and Grey Relational Analysis (GRA). Composites were fabricated using varying fiber volume fractions (20%, 30%, and 40%), particle sizes (20 μm, 60 μm, and 100 μm), and curing temperatures (60°C, 80°C, and 100°C) in a 3-factor, 3-level experimental design. Key properties such as tensile strength, impact …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 75–85 Read article
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Carbon Capture Technologies: Innovations, Challenges, and Environmental Implication
Abstract: This review work provides a comprehensive overview of carbon capture and storage (CCS) technologies, their status, and future directions. It examines various capture methods, including pre-combustion, post-combustion, oxyfuel combustion, and direct air capture, as well as emerging and hybrid technologies such as metal-organic frameworks, ionic liquids, and microencapsulation. The study discusses the limits of current technologies and attempts to point out innovations needed to ameliorate these challenges. It also explores …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 15, Issue 1, 2025 · pp. 7–18 Read article