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348 articles for “Regulations”
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Vitamin D Mitigates Inflammation and Downregulates Importin α3 in Non-Alcoholic Fatty Liver Disease (NAFLD)
Abstract: Background: Pro-inflammatory cytokines, such as TNF-α, IL-1β, IL-6, and IL-8, seem to play a crucial role in the progression of NAFLD as they activate the transcription factor NF-кB. The activated NF-кBp50/RelA subunits are translocated to the nucleus by Importin α3 and Importin α4. Numerous studies have indicated a negative association between NAFLD and vitamin D levels. Low vitamin D levels have been correlated with histological severity, necro-inflammation, and fibrosis in …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 1–16 Read article
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The Renaissance and Resilience of CB1 Reverse Agonists: From Central Liabilities to Peripheral Promise
Abstract: Building upon these foundational insights, current research has increasingly focused on refining the pharmacological profile of CB1 reverse agonists to maximize therapeutic benefit while minimizing central adverse effects. The adverse neuropsychiatric outcomes associated with first-generation agents such as Rimonabant including anxiety, depression, and suicidal ideation highlighted the critical role of central CB1 receptors in mood regulation. Consequently, drug development strategies have shifted toward peripherally restricted CB1 reverse agonists that exhibit …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 30–35 Read article
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Green Finance and India’s Climate Commitments: Aligning Financial Systems with Sustainable Development Goals
Abstract: India’s commitment to addressing climate change, as reflected in its Nationally Determined Contributions (NDCs), net-zero ambitions, and alignment with the United Nations Sustainable Development Goals (SDGs), has placed green finance at the center of the country’s sustainable development agenda. Green finance involves directing capital and investment flows toward projects and initiatives that are environmentally sustainable. It supports efforts to reduce climate-related risks, enhance resilience to environmental changes, and promote economic …
Published in International Journal of Sustainability · Vol. 3, Issue 1, 2026 · pp. 49–54 Read article
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Influence of Antibiotic Promotion Practices on Pharmacovigilance and Resistance Reporting Patterns
Abstract: The global escalation of antimicrobial resistance (AMR) has emerged as a critical public health crisis, undermining decades of therapeutic advancements. While inappropriate prescribing and misuse of antibiotics are widely acknowledged contributors, the role of pharmaceutical promotion practices remains underexplored in influencing prescribing behaviors and downstream pharmacovigilance systems. This review critically examines how antibiotic promotion strategies – ranging from direct physician engagement to digital marketing – affect adverse drug reaction (ADR) …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 1–11 Read article
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Consumer Misuse of Cosmeceuticals and Its Role in Adverse Skin Reactions
Abstract: Cosmeceuticals represent a rapidly expanding category of products positioned between cosmetics and pharmaceuticals, offering both aesthetic and therapeutic benefits. However, their widespread availability, aggressive marketing, and perception as inherently safe have contributed to increasing instances of consumer misuse. Misuse includes over-application, inappropriate combinations, prolonged unsupervised use, and use of high-potency active ingredients without dermatological guidance. Such practices have been strongly associated with a broad spectrum of adverse cutaneous reactions ranging …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 2, 2026 · pp. 1–16 Read article
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Effect of Skin Barrier Damage on Absorption and Action of Cosmeceuticals
Abstract: The skin acts as a primary defensive barrier protecting the human body against environmental aggressors, microbial invasion, and chemical exposure. The integrity of the skin barrier, particularly the stratum corneum, plays a crucial role in regulating the permeation of substances applied topically. Cosmeceuticals, a hybrid category between cosmetics and pharmaceuticals, are designed to deliver biologically active ingredients into the skin to exert therapeutic or beneficial effects. However, the condition of …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 2, 2026 · pp. 1–19 Read article
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Functional Biomolecules in Animal Nutrition: Biochemical Mechanisms and Their Impacts on Growth Performance and Health Outcomes
Abstract: Functional biomolecules have emerged as critical modulators of animal nutrition, extending beyond conventional nutrient supply to regulate biochemical and physiological processes that determine growth performance and health outcomes. This review synthesizes current knowledge on diverse classes of bioactive compounds, including amino acids, peptides, fatty acids, vitamins, minerals, phytochemicals, and microbial-derived metabolites, and their roles in livestock systems. Emphasis is placed on underlying biochemical mechanisms such as enzyme activation, nutrient signaling …
Published in International Journal of Nutritions · Vol. 3, Issue 2, 2026 Read article
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Muscle vs. Heart: A Comprehensive Review of Anabolic Steroid-Induced Cardiovascular Risks
Abstract: Anabolic-androgenic steroids (AAS) are widely used by athletes and bodybuilders to enhance muscle mass and performance. However, their misuse is associated with serious and often underrecognized cardiovascular risks. Despite their popularity, particularly among young adults, the long-term consequences of AAS abuse on cardiovascular health remain insufficiently explored in the literature. This review aims to: 1. Analyze the cardiovascular implications of AAS use. 2. Elucidate the molecular and physiological mechanisms contributing …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 2, 2026 Read article
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IoT-Based Real-Time Monitoring System for Temperature and Humidity Control in Pharmaceutical Manufacturing
Abstract: Environmental conditions, especially temperature and humidity, play a vital role in pharmaceutical manufacturing processes. Even minor fluctuations in these parameters can significantly influence the stability, potency, and overall effectiveness of drug formulations. In many cases, uncontrolled environmental variations may lead to chemical degradation, reduced shelf life, contamination risks, and substantial financial losses for manufacturers. Therefore, maintaining precise and consistent environmental conditions is essential to ensure product quality, regulatory compliance, and …
Published in International Journal of Mobile Computing Technology · Vol. 4, Issue 1, 2026 · pp. 32–37 Read article
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Disaster Management for the Production Process in Manufacturing Industries
Abstract: In manufacturing and businesses in general, damages occurring during production must be recorded. Production is carried out continuously every day through various processes that make up the supply chain. This process is often ineffective and causes damage. These disasters cause economic damage and losses, sometimes even death. These damages may result from accident, negligence or incompetence. There are other things around. This article focuses on damage elements associated with the …
Published in International Journal of Manufacturing and Production Engineering · Vol. 4, Issue 1, 2026 · pp. 16–19 Read article
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Digital Literacy: A Faculty-Based Comparative Study of Research Scholars at the University of Rajasthan
Abstract: This study explored how much “research scholars in the department of Social Science and Arts of the University of Rajasthan, Jaipur”, understand and use digital technologies. The findings based on 84 questionnaires show that scholars of the Social Science faculty have a relatively high digital literacy compared to those in the Arts faculty. Most of the respondents indicated that they were skilled in using open-access sources. However, about a quarter …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 2, 2026 · pp. 34–43 Read article
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Prediction of Molecular Targets for Anthraquinone and Its Analogs for Treatment of Good Pasteur Syndrome
Abstract: Objective: In order to find prospective molecular targets for the treatment of Good Pasteur Syndrome (GPS), a rare autoimmune disease that affects the kidneys and other organs, computational methods and network pharmacology were applied in this work. The goal of the study is to identify particular human proteins that might interact with anthraquinone and its analogues as well as to uncover potential mechanisms of action by which these drugs might …
Published in International Journal of Bioinformatics and Computational Biology Read article
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"Reviving Kali Bein : Addressing the Re-Pollution Sources and and Exploring Solutions for Sustainable River Management"
Abstract: All aspects of the earth’s environmental system are impacted by human assault on the planet that includes vast conversion of land use, extraction of mineral resources, use and misuse of surface water and ground water which altered the natural flow of energy and resources within the environment. This paper reviews the present position of kali ben rivulet, which flows through the state of Punjab in India, has found to be …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 1, 2023 · pp. 12–26 Read article
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ECZEMA {Atopic Dermatitis}
Abstract: Many of the persons around the world suffer from eczema which is also called atopic dermatitis. It is a kind of skin disorder that makes the skin dry, itchy, and sometimes even painful. There is no specific age group who got affected by this particular disease, no matter what age you are. But particularly it is seen that the children were mostly affected by eczema, as there is no cure …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 53–66 Read article
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A Critical Study of Research Challenges for Self-adaptive Software
Abstract: Software systems dealing with distributed applications in changing environments normally require human supervision to proceed with activity in all conditions. These rearranging, investigating, and all in all upkeep errands prompt exorbitant and tedious strategies amid the working stage. These issues are principally because of the open-circle structure regularly followed in programming advancement. Hence, there is popularity for administration many-sided quality decrease, administration mechanization, vigor, and accomplishing the majority of the …
Published in International Journal of Computer Science Languages · Vol. 1, Issue 1, 2023 · pp. 1–6 Read article
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To Assess the Knowledge and Practices Regarding Postnatal Assessment of Women Among Nurses Working in Gynaecology Units of Selected Hospitals of District Ludhiana, Punjab: A Descriptive Study
Abstract: This study was done to evaluate nurses' postnatal assessment of women's knowledge and practices. Postnatal assessment is a vital part of postnatal care in the fourth stage of labor for the women as it confirms the mother’s recovery from the effects of pregnancy, labor, and delivery. It provides an opportunity for the nurses to prevent many life-threatening complications and promote health status during this period. A descriptive research design was …
Published in International Journal of Midwifery Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 17–24 Read article
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A Comparative Study on Associated Factors of Hypertension Among Working Women and Non-working Women
Abstract: Background: One in four people worldwide is affected by high blood pressure, which is also the third leading cause of illness and a significant risk factor for death. Compared to non-working women, employed women had a higher prevalence of hypertension. This might be attributed to various factors such as job-related stress, lack of relaxation, and lack of physical activity. Method: Quantitative approach was adopted. To investigate the related determinants of …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 09–14 Read article
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The Nursing Perspective: Emerging Competencies in Midwifery and Neonatal Care
Abstract: A skilled attendant is a qualified healthcare practitioner, such as a midwife, doctor, or nurse, who has received appropriate education and training to effectively handle uncomplicated pregnancies, childbirth, and the immediate postnatal period. They are equipped to identify, manage, and refer any complications that may arise in women and newborns. Skilled attendants have the necessary knowledge and skills to manage normal pregnancies and childbirth, and their presence during delivery is …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 21–26 Read article
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Evaluating the Performance of Mobile Air Compressor Component of Radiator Unit using the Application of Reliability
Abstract: The application of reliability to monitor and predict the performance of mobile air compressor component of radiator unit was considered in this research. This study demonstrated some of the root causes of the radiator unit failure as effect of temperature and the nature of coolers used, because these two parameters cause corrosion, affect shortage on fluid level and in turn influence the internal heat generated by radiator unit of the …
Published in International Journal of Pollution: Prevention & Control · Vol. 1, Issue 1, 2023 · pp. 39–43 Read article
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The Past, Present, and Future of Power Conversion Technologies for Computer, Networking, and Telecom Power Systems
Abstract: The power systems of modern computers, networking, and telecom equipment face formidable challenges due to the ongoing increase in power-density and efficiency requirements. Significant technological breakthroughs in system designs, devices and materials, topology optimization, and packaging/thermal design will be necessary to meet these objectives. To address these challenges, ongoing research and development efforts are being conducted in academia, industry, and government institutions. These efforts aim to revolutionize power system designs, …
Published in International Journal of Information Security Engineering · Vol. 1, Issue 1, 2023 · pp. 16–31 Read article