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300 articles for “K-factor”
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Identification of Secondary Metabolites from Zingiber officinale as Inhibitors for Keap 1-Nrf2 small Molecules through Molecular Docking Techniques
Abstract: Objective: Therapeutic plants aid in treating cancer-based cell signaling pathways and preventing certain risk factors. Zingiber officinale has a variety of anti-inflammatory characteristics also contributing to enhanced immunity, reducing cancer risk and used to target the KEAP NRF2. When overexpressed in response to oxidative stress and DNA damage, elevates the risk of developing multiple cancers. NRF2 cellular sensors, which also control and coordinate their expression aid in defending healthy cells …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 35–48 Read article
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Next Generation Sequencing (NGS) in Personalized Medicine: Emphasizing Public Health Beyond Reality
Abstract: NGS is a modern technology that allows researchers to quickly sequence large amounts of DNA or RNA, it is also known as massively parallel sequencing or deep sequencing. NGS has revolutionized genomic research and biological sciences by its speed, scale, accuracy, ultra-high throughput, and cost. NGS replaced the conventional sequencing method. A novel idea in healthcare is precision medicine, which involves adjusting medical care to each patient’s unique traits and …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 1–17 Read article
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Impact of Climate Change on Economy of Nepal with Special Edges on Tourism Industry: Threats to Development and Stability
Abstract: Nepal is rich in biodiversity with Himalayan ecosystems and natural resources. Nepal's natural resources are a valuable and cultural asset for local communities, as well as supporting many of the country's industries. Safety is an important part of nature tourism and can attract or repel tourists. Climatic factors include temperature, precipitation, clouds, air, wind, and humidity. A key component of the industry's expansion is making traveler access safe and simple. …
Published in International Journal of Climate Conditions · Vol. 1, Issue 2, 2024 · pp. 31–38 Read article
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From Rural to Urban: Understanding Taobao Villages to Redress Planetary Urbanisation
Abstract: This study examines Taobao Villages as an innovative model of urbanisation under China’s planetary urbanisation framework. These rural communities, driven by the rise of e-commerce and digital infrastructure, have successfully integrated into the broader urban ecosystem by reconfiguring their historical socio-spatial legacies. Through Lefebvre’s spatial triad framework, the research identifies three key historical legacies that underpin this transformation: (1) Collective Production Practices: Rooted in socialist collectivisation, these legacies include organisational …
Published in International Journal of Urban Design and Development · Vol. 3, Issue 1, 2025 · pp. 1–7 Read article
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Cost Model of Acquisition and Merger in Construction Industry
Abstract: Merger and Acquisition in India is at an all-time high with more buyers now than before; it has been accounting for 80% of closed deals in 2020–2021, up from 70% in 2017–2019. To determine the Merger and Acquisition of the company, this article explores the main factors in the Merger and Acquisition process. And also study the main framework of the Merger and Acquisition. And, also, the article discusses the …
Published in International Journal of Architectural Design and Planning Read article
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Analysis of critical constraint factors affecting the performance of Transportation projects
Abstract: Infrastructure is a country's biggest source of economic growth, which is made up of a variety of facilities and processes. It includes all the amenities and services required for urbanization, economic expansion, improved quality of life, and thriving companies. Transportation is one of the most important industries for any nation's economy, but constraints exist in all working environments. A construction constraint is a condition that makes it difficult to achieve …
Published in International Journal of Urban Design and Development · Vol. 1, Issue 1, 2023 · pp. 54–78 Read article
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Concurrent Infection of Influenza and COVID-19: A Review
Abstract: In December 2019, a novel coronavirus that causes respiratory illnesses was identified in Wuhan, China, and swiftly spread around the world. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a virus that spreads via the respiratory system and can cause pneumonia. Members of the Orthomyxoviridae family include influenza viruses. Although there are four genera in this family, influenza is only caused by genera A and B, which are clinically important for …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 7–15 Read article
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Foxtail Millet (Setaria italica): A Detailed Review on Nutritional Value, Anti-Nutritive Value, Potential Health Benefits
Abstract: Millets are a diversified collection of small-seeded grasses that have been used as a primary source of grain for generations in various regions of Asia and Africa. Millets are a staple grain this is historically consumed in dry regions everywhere in the international. They are high in protein, fats, minerals, nutrients, and fiber.. Millets are highly nutritious grains rich in essential amino acids, minerals, and dietary fiber, offering health benefits …
Published in International Journal of Nutritions · Vol. 1, Issue 2, 2024 · pp. 20–26 Read article
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A Comprehensive Review of AI-Driven Strategies for Tailored Wellness and Dietary Recommendations
Abstract: In today’s fast-paced world, health and fitness have become top priorities for many individuals. As a result, people increasingly turn to mobile apps and digital tools to track their wellness goals, follow diet plans, and stay fit. However, most of these apps provide the same set of recommendations for all users, ignoring the fact that everyone has different needs. This one-size-fits-all approach often fails to keep users engaged and motivated, …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 3, Issue 2, 2025 · pp. 16–20 Read article
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REVIEW OF PHARMACOEPIGENETICS: BRIDGING EPIGENETICS AND PERSONALIZED MEDICINE
Abstract: Pharmacoepigenetics is an emerging field that explores how alterations in gene expression, independent of DNA sequence changes, influence individual responses to drugs. Unlike pharmacogenetics, which focuses primarily on genetic variation, pharmacoepigenetics integrates genetic, environmental, and lifestyle factors to explain interindividual differences in drug efficacy, toxicity, and resistance. Key epigenetic mechanisms including DNA methylation, histone modifications, non-coding RNAs, and RNA methylation play critical roles in regulating drug metabolism and therapeutic outcomes. …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Pros and Cons of Adopting Artificial Diet for Silkworms
Abstract: Silkworms (Bombyx mori L.) were renowned for their ability to produce silk fibers and have played an essential role in the textile industry for thousands of years. Traditionally, these insects have been raised on mulberry leaves which provide them with the necessary nutrients to grow and spin silk. However, in recent years, advancements in agricultural and industrial practices have led to the development of artificial diets for silkworms. These synthetic …
Published in International Journal of Insects · Vol. 2, Issue 1, 2025 · pp. 7–11 Read article
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A Futuristics Pyrolysis Technique: Conversion of Waste Plastic Polybags Into Fuel
Abstract: Plastics are high molecular weight materials composed of repeating polymer units and can be classified based on factors like chemical composition, structure, stiffness, application types, and processing methods. A key environmental issue with plastics is their non-biodegradability, causing them to persist in the environment. Pre-consumer plastic waste includes manufacturing defects, rejected items, and excess materials produced during virgin plastic manufacturing. In India, around 15,342 tons of plastic waste are collected …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 1, 2025 · pp. 1–13 Read article
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LoRa and LoRaWAN in the IoT: Performance, Challenges, and Future Opportunities
Abstract: This paper provides a broad overview of both LoRa and LoRaWAN technologies in the context of Internet of Things (IoT). The market need for communication technology to be low-power and long-range continues to grow, and LoRa and LoRaWAN are emerging as viable options for enabling widespread IoT applications in a variety of applications. This review offers structured and comparative assessment of their functionality in different environments, such as urban, rural, …
Published in International Journal of Wireless Security and Networks · Vol. 4, Issue 2, 2026 Read article
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Partitioning Dynamics of Nutrients in Transition Dairy Cows: Metabolic, Hormonal, and Cellular Mechanisms Affecting Lactation and Fertility
Abstract: This review critically examines nutrient partitioning dynamics in dairy cows during the transition phase, a period that profoundly affects lactation and reproductive performance. During this phase, cows experience extensive physiological changes that alter nutrient requirements and utilization, making effective management essential for health and productivity. The review synthesizes current research on mechanisms of nutrient partitioning, with particular attention to energy, protein, and mineral balance, which are crucial for optimizing milk …
Published in International Journal of Nutritions · Vol. 3, Issue 1, 2026 Read article
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Tamil Migration to Colonial Malay and Burma from 1880-1920: Analysing the Acculturation Process through the Lens of Fashion
Abstract: This paper seeks to understand the cultural repercussions of colonial labour migration, which emerged as one of the key characteristics of the 19th century as European nations set up colonies in parts of Africa, Latin America, and South and Southeast Asia. The ‘coolie’ market consisted of indentured labourers and slaves and allowed the colonial rulers to supplement labour in new colonies. As the labourers migrated to new lands, they carried …
Published in International Journal of Trends in Humanities · Vol. 1, Issue 2, 2024 · pp. 19–24 Read article
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The Mycobiome Frontier – Pre & Post 2020 Status: Integrating Fungal Bioactive Compounds, Probiotics, and Antimicrobial Peptides in Modern Therapeutics and Biotechnology.
Abstract: The fungal kingdom represents an indispensable resource in modern therapeutics and biotechnology, offering a diverse array of bioactive compounds, probiotics, and antimicrobial peptides (AMPs). Functional fungal polysaccharides (FFPs), such as beta-glucans, chitin, and mannans, are centrally involved in modulating the human gut microbiota, providing novel therapeutic avenues for chronic conditions including diabetes, neurodegenerative disorders, and cancer. These compounds act as prebiotics, nourishing beneficial bacteria and enhancing metabolic parameters such as …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 1–11 Read article
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HPV and Cardiovascular Risk: Unpacking a Novel Link Between Viral Infection and Heart Disease
Abstract: Human papillomavirus (HPV) is best known for its oncogenic potential, yet a growing body of evidence suggests that persistent HPV infection may also contribute to cardiovascular disease (CVD). In 2025, pooled analyses and conference reports galvanized attention by estimating that HPV‐positive individuals have ~40% higher risk of CVD and approximately double the risk of coronary artery disease (CAD) compared with HPV‐negative peers, even after adjustment for traditional risk factors. These …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 1–5 Read article
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Samelisant, an H3 Receptor Agonist as an Anti-Alzheimer Potential – A Pilot Study on Molecular Docking
Abstract: Neurodegenerative diseases have become more prevalent and about 55 million of the population are affected by dementia globally. One of the most important neurodegenerative diseases is Alzheimer’s disease which is known for its effect on memory and cognitive impairment. Alzheimer’s disease (AD) is an area of intense scientific investigation due to its high prevalence and the lack of a definitive cure. Amyloid precursor protein plays a central role in Alzheimer’s …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 15–26 Read article
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Forecasting Climate-Driven Healthcare Demand in Agricultural Regions: A Multi-Modal AI Approach
Abstract: The rapidly increasing instability of world climatic regimes has made past meteorological thresholds irrelevant, especially in the agricultural areas where monetary stability and well-being of humans are closely intertwined with an environmental situation. The more the frequency of 1 in every 1000-year events, i.e., heatwaves and catastrophic flooding increase, the greater the rural healthcare systems are in crisis, i.e., unable to predict a surge in demand because of data scarcity, …
Published in International Journal of Climate Conditions · Vol. 2, Issue 2, 2025 · pp. 28–38 Read article
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Factors Influencing the Design of Parabolic Trough Collector: A Review
Abstract: Due to limited resource availability and high conventional energy usage, research into renewable energy has increased during the past few years. Utilizing collecting systems, significant renewable energy can be produced from the available solar radiation. The majority of solar energy harvesting systems use parabolic trough concentrating collectors. The performance of parabolic trough collectors as a whole is examined in this paper. The operating characteristics, such as the type of receiver …
Published in International Journal of Energy and Thermal Applications · Vol. 1, Issue 2, 2023 · pp. 1–8 Read article