Search
180 articles for “Drug Formulation”
-
3D-Printed Polymeric Drug Delivery Systems for Personalized Medicine
Abstract: Personalized medicine has revolutionized healthcare by tailoring treatments to individual patient needs. Among the emerging technologies, 3D printing has demonstrated immense potential in fabricating polymeric drug delivery systems with precise control over drug release, dosage, and bioavailability. These systems offer customized therapeutic solutions, improving efficacy while reducing adverse effects. This paper provides an overview of 3D-printed polymeric drug delivery systems, discussing the types of polymers used, fabrication techniques, applications in …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 313–325 Read article
-
Formulation Challenges in Long-acting Injectable Small Molecules: Emerging Strategies and Perspectives
Abstract: Long-acting injectable (LAI) formulations represent a transformative approach in pharmacotherapy, particularly for conditions demanding sustained drug exposure over weeks to months. Although biologics have dominated this space historically, the adaptation of LAI technology to small molecules presents a distinct and complex set of challenges rooted in physicochemical properties, manufacturing scalability, and regulatory expectations. This review systematically addresses the principal formulation barriers encountered in developing LAI small-molecule products, including aqueous solubility …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
-
Ocular Films as a Drug Delivery System Against Fungal Infections: Current Insights and Future Directions
Abstract: Fungal infections of the eye, including keratitis, endophthalmitis, and blepharitis, represent a challenging class of ocular diseases due to their potential for vision loss and the limited efficacy of existing treatments. These infections are caused by a range of pathogenic fungi, such as Aspergillus, Candida, and Fusarium species, and often require long-term therapeutic intervention. Conventional topical antifungal therapies, such as eye drops and ointments, suffer from poor ocular bioavailability due …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 101–109 Read article
-
Biodegradable and Natural Fiber-Reinforced Polymer Composites for Sustainable Biomedical Applications
Abstract: Liposomal drug delivery has evolved into a viable approach in modern pharmacology thanks to its enhanced bioavailability, reduced systemic toxicity, and targeted drug release. Conventional liposomes have limited stability, medicine leakage, and short circulation times among other problems. Overcoming these limits, the inclusion of nano-polymers into liposomal formulations has transformed medication delivery. Thorough research has been done on the potential of nano-polymers including chitosan, hyaluronic acid, polyethylene glycol (PEG), and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 420–432 Read article
-
Botanical Beauty: Exploring the Role of Herbal Drugs in Modern Cosmetics
Abstract: This review provides a concise overview of the burgeoning use of herbal drugs in cosmetics, showcasing their increasing importance in modern skincare formulations. Through an exploration of various herbal plants and their extracts, such as Aloe vera, lavender, calendula, and green tea, among others, the review elucidates the diverse array of benefits these botanicals offer for skin health and overall well-being. By harnessing the therapeutic properties of these natural ingredients, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 76–91 Read article
-
Development and Optimization of Orally Disintegrating Tablets (ODTs) Containing Standardized Curcumin Extract for Enhanced Bioavailability and Patient Compliance
Abstract: This research centers on creating and perfecting orally disintegrating tablets with standardized curcumin extract to both increase its bioavailability and promote better patient adherence. Although curcumin has numerous therapeutic applications. It remains clinically ineffective due to its poor aqueous solubility and bioavailability constraints. The development of orally disintegrating tablets involved direct compression with various levels of superdisintegrants including sodium starch glycolate and cross povidone to address existing challenges. Research teams …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 3, 2025 · pp. 1–06 Read article
-
Strategies for the Development and Optimization of Orally Disintegrating Tablets (ODTs) to Improve Bioavailability and Patient Compliance
Abstract: Background: Pharmaceutical scientists have developed Orally Disintegrating Tablets (ODTs) to advance patient drug acceptance and biological system availability through simplified medi-cation delivery especially for children and senior citizens and people who cannot swallow pills regularly. The oral disintegrating tablets dissolve in the mouth within thirty seconds or less (USP 701) while needing no additional liquid thus making them suitable for both emergency treatments. Objective: The research examines ODT development strategies …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
-
Secondary Metabolites in Drug Development: Tracing Their Historical and Therapeutic Impact
Abstract: Secondary metabolites, also known as natural products, exhibit a level of structural and chemical diversity unmatched by synthetic small molecule libraries. These compounds, which have evolved to possess drug-like properties, continue to be a primary source for new medications and drug leads. Their discovery has significantly impacted advancements in chemistry, biology, and medicine, influencing drug development and therapeutic strategies throughout history. Derived from primary metabolic pathways such as photosynthesis, glycolysis, …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 51–55 Read article
-
Herbal Drug Used in the Treatment of Diabetes: A Review
Abstract: Background: Diabetes mellitus is a chronic disease that occurs at the point when the pancreas is not able to produce insulin, or when the body cannot utilize the insulin it produces. Diabetes mellitus is a complex metabolic disorder that affects various systems of body such as visual, circulatory, renal and nervous system. Human beings depend upon plants for their various needs such as food, fodder, fuel, timber, fibres, dyes, gums, …
Published in Research & Reviews : Journal of Herbal Science Read article
-
Development and Evaluation of a Cost-Effective UV-Protective Cream Containing Para-Aminobenzoic Acid and Aloe Vera for Indian Climatic Conditions.
Abstract: The increasing incidence of ultraviolet (UV) radiation-induced skin disorders has heightened the demand for effective, affordable photoprotective agents, especially in countries with high sun exposure such as India. This study aimed to develop a cost-effective and efficient UV-B protective cream formulation suitable for populations in Indian latitudes. Para-aminobenzoic acid (PABA) was selected as the primary sunscreening agent due to its high UV-B absorption efficiency, low toxicity, and affordability compared with …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 2, 2025 · pp. 7–18 Read article
-
Design and Development of Novel Floating Drug Delivery Systems
Abstract: Recent advances in science and technology have greatly aided in the creation of novel drug delivery methods, especially in addressing physiological issues including irregular stomach emptying times and brief stomach residence periods. Long-term stomach absorption is the goal of gastro-retentive dosage forms (GRDF). Floating drug delivery systems, expanding or swelling systems, polymer-based bioadhesive systems, high-density systems, and other ways that postpone stomach emptying are just a few of the techniques …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 1–22 Read article
-
Review on Sustained Released Matrix Tablet
Abstract: Pharmaceuticals often use sustained release dose forms to prolong the therapeutic agent’s presence in the bloodstream and maintain a consistent plasma profile. The matrix governs the drug’s release rate. Hydroxypropyl methyl cellulose, a release retardant, is a key excipient in formulations due to its ability to promote sustained release. Techniques that include wet granulation, direct compression, or the dispersion of solid particles within a porous matrix, integrating polymers, like polymethyl …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 60–69 Read article
-
Nanomedicine in Combination with Artificial Intelligence (AI): Transforming Cancer Treatment
Abstract: The convergence of nanomedicine and artificial intelligence (AI) holds transformative potential for advancing cancer treatment, particularly in liver cancer. Nanomedicine enables the development of targeted drug delivery systems, enhanced imaging modalities, and precise therapeutic interventions, while AI facilitates data-driven decision-making, personalized treatment plans, and predictive analytics. This synergistic approach can significantly improve the diagnosis, treatment, and monitoring of liver cancer by optimizing the use of nanoparticle-based therapies. AI-powered algorithms can …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 27–30 Read article
-
Preparation and Evaluation of Herbal Gel Containing Multiple Plant Extracts for Acne Treatment
Abstract: A persistent inflammatory condition affecting the pilosebaceous unit, acne is caused by an increase in sebum production by sebaceous glands and an incorrect desquamation of hair follicles in response to rising testosterone levels throughout teenage years. Follicular obstruction results in follicular distention, which frequently triggers an inflammatory reaction and the growth of the Propionibacterium acnes bacteria. This project mainly focused on the formulation of a herbal gels for acne. These …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 2, 2025 · pp. 18–30 Read article
-
Gastro Retentive Drug Target System: Its Needs, Advantages, Limitation and Approaches
Abstract: Background: Gastro retentive drug delivery systems (GRDDS) address limitations of oral therapy for drugs with poor solubility, instability at intestinal pH, or narrow absorption windows by prolonging gastric residence and increasing contact with the gastric mucosa. Objectives: To review GRDDS approaches—floating systems, mucoadhesive systems, and super porous hydrogels—with emphasis on formulation strategies and polymer–excipient selection to enhance gastric retention, modulate buoyancy/swelling/adhesion, and ultimately improve oral bioavailability and therapeutic outcomes for …
Published in Trends in Drug Delivery · Vol. 13, Issue 2, 2026 Read article
-
Application of Natural and Synthetic Polymer-Based Disintegrants in the Design of Fast Dissolving Cefuroxime Axetil Tablet Composites
Abstract: The current paper examines how natural and synthetic polymer-based disintegrants can be used to design fast-soluble types of tablet composites. A model drug was chosen and tablets were prepared by the direct compression method using different polymeric excipients, such as guar gum, locust bean gum, sodium starch glycolate (SSG) and cross povidone. Eight formulations were prepared and tested on the basis of critical material and performance characteristics including thickness, hardness, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1348–1360 Read article
-
Using Artificial Intelligence for The Design of Polymeric Drug Delivery Systems
Abstract: AI is cost effective and time efficient process. Artificial intelligence is a method which uses high speed calculation, the improvement regarding algorithm along with collection about biological and chemical features in pharmaceutical exploration and development .Present day because continuous progress towards machine learning (ML),Artificial intelligence an effective statistics analysing technology might have been broadly utilized in drug design .In pharmaceutical exploration and research employ of AI in target identification, compound …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 1018–1027 Read article
-
Melanoma Skin Cancer Detection Using Deep Learning
Abstract: Cancer as one of the major diseases rank in the World is still very challenging to diagnose and treat hence need for the technological advancements. Chemotherapy, radiation, as well as surgery therapies have several drawbacks including non-selective action, damage to healthy tissues, and multi-drug resistance. Smart nano-theranostics, an advanced integration of nanotechnology with diagnostic and therapeutic modalities, offers a next-generation approach for precision oncology. Thus, the development of multifunctional nanoparticles …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 2, 2025 Read article
-
Formulation and Evaluation of herbal multipurpose cream
Abstract: Multipurpose creams are semi-solid preparations used to lower the risk of skin disorders and fight wrinkles. The primary goal of the research is to produce multipurpose creams utilizing various herbs and then analyze their efficacy. The herbs utilized in the preparations include dried bael leaf powder, amla powder, neem powder and bael leaves. The article emphasizes the importance of topical drug delivery systems in dermatology, highlighting the benefits of delivering …
Published in Recent Trends in Cosmetics · Vol. 1, Issue 2, 2024 · pp. 44–57 Read article
-
Nanotechnology In Herbal Medicine
Abstract: Herbal medicine has been widely used for centuries as a natural and holistic approach to health care. However, many herbal compounds face challenges such as low solubility, low bioavailability, instability, and the lack of targeted delivery, which affect their efficacy. The integration of nanotechnology into herbal medicine has emerged as a promising strategy to overcome these challenges and enhance the pharmacological potential of plant-derived compounds. Nanocarriers such as liposomes, solid …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 1, 2025 · pp. 50–69 Read article