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697 articles for “Computational Studies”
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Prediction of Molecular Targets for Anthraquinone and Its Analogs for Treatment of Good Pasteur Syndrome
Abstract: Objective: In order to find prospective molecular targets for the treatment of Good Pasteur Syndrome (GPS), a rare autoimmune disease that affects the kidneys and other organs, computational methods and network pharmacology were applied in this work. The goal of the study is to identify particular human proteins that might interact with anthraquinone and its analogues as well as to uncover potential mechanisms of action by which these drugs might …
Published in International Journal of Bioinformatics and Computational Biology Read article
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In Silico Prediction of Multitarget Mechanism of Quinoline and Its Analogs on Phosphoinositide-3-Kinase Pathway Proteins
Abstract: Objective: Phosphoinositide 3-kinases (PI3Ks), the target of rapamycin (PI3K/Akt/mTOR, PAM), are a family of enzymes that play a role in the growth, proliferation, differentiation, motility, survival, and intracellular trafficking of cells, all of which are essential for healthy cellular function and are also connected to cancer. In this study, quinoline and its derivatives were employed to analyze its inhibition activity on the phosphoinositide-3-kinase pathway. Methods: In this work, eight phytocompounds …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 57–76 Read article
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Stilbenes: A Molecular Docking and ADMET Analysis Approach on an Emerging Resource for Scavenging Reactive Oxygen Species in the Field of Colon Malignancy
Abstract: Objective: Colon malignancy, also referred to as colon cancer, originates as precancerous polyps in the colon or rectum, which have the potential to thrive and progress into cancerous tumors over time. This study delves into various bioactive compounds (from natural sources like plants) to assess their potential efficacy in inhibiting colon malignancy as compared to conventional methods. Methods: The objective of this study was to employ computational methodologies to evaluate …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 3, 2024 · pp. 29–38 Read article
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In silico Molecular Docking Analysis of Stephania glabra phytocompounds Targeting Thymidylate Kinase for potential Antituberculosis Activity
Abstract: Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis. It mainly affects the lungs and spreads through the air when a person with active TB in their lungs coughs, sneezes, or spits. This study investigates several bioactive compounds derived from plants to forecast how effective plant-based ligands will be at preventing tuberculosis. The purpose of the study was to use computational techniques to assess the effectiveness of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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Tri-Band Edge-Cut Rectangular Microstrip Patch Antenna on Composite Substrate for RF Energy Harvesting in IoT Networks
Abstract: The increasing use of Internet of Things devices underscores the pressing need for sustainable energy solutions, since traditional batteries necessitate regular replacement and constrain scalability. Radio frequency energy harvesting is a viable option; nonetheless, antenna design continues to provide a significant problem owing to the requirements for compactness, efficiency, and multi-band functionality. A hybrid composite substrate configuration combining FR4 (εr = 4.3) and RT Duroid (εr = 2.2) is employed …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 867–883 Read article
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Technometric Portrait of Sri Vinod Dham, an Indo-US Engineer, Father of Intel Pentium Process: A Quantitative Analysis
Abstract: Vinod Dham is recognized as the ‘Father of Pentium Chip’ or ‘Father of Intel Pentium Process’ in the field of the computer industry, and as an Indo-American pioneer from Silicon Valley. He has contributed 10 research papers during 1982–1986, with an average of two papers per year. This study tries to analyze his contributions through a bibliometric study and draw his familiarity as a world-famous electronic technologist. Data has been …
Published in Research & Reviews : Journal of Statistics · Vol. 14, Issue 3, 2025 · pp. 16–25 Read article
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Computational Identification of Antigenic Proteins and Epitopes in Hantavirus sp. for Drug Repurposing
Abstract: Hantavirus is an emerging virus that spreads from animals to humans and can cause serious illnesses like hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS). there are no FDA-approved treatments available for these diseases. This study explores in-silico drug repurposing as a strategy to identify potential therapeutic candidates. The physicochemical, secondary structure, antigenicity, and post-translational modification analysis of hantavirus proteins – specifically the glycoprotein precursor, N protein, …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 20–26 Read article
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Generic Virtual Mouse
Abstract: The mouse and keyboard have been replaced by new input mechanisms brought about by the quick development of Human-Computer Interaction (HCI). Using computer vision and deep learning techniques, this study explores the possibility of replacing actual mouse inputs in a computer system with hand gestures. We created a virtual mouse system that uses a normal webcam to record hand motions. Computer vision algorithms then process these gestures to handle mouse …
Published in Current Trends in Signal Processing · Vol. 15, Issue 2, 2025 · pp. 26–32 Read article
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A Comprehensive Study of Natural Language Processing Systems Using Modern Programming Languages: Techniques, Architectures, Experimental Evaluation, and Applications
Abstract: Natural Language Processing is a key field of study within artificial intelligence that focuses on enabling machines to understand and work with human language. This is because there is much digital text data everywhere. Natural Language Processing is what this study is about. It looks at new ways of doing Natural Language Processing. The old ways are like machine learning and the new ways are like learning. This study compares …
Published in Recent Trends in Programming languages · Vol. 13, Issue 1, 2026 Read article
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Innovations in Healthcare IT for Enhanced Patient Outcomes
Abstract: Healthcare IT innovations are transforming medical services by enhancing diagnostics, improving patient management, and optimizing resource utilization. The integration of advanced technologies has led to significant improvements in healthcare delivery, enabling more accurate diagnoses, efficient treatments, and seamless data management. One of the most impactful advancements is Electronic Health Records (EHR), which facilitate centralized patient data storage, allowing healthcare providers to access and update records in real-time. Telemedicine has revolutionized …
Published in Current Trends in Information Technology · Vol. 15, Issue 2, 2025 · pp. 19–23 Read article
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AI for Cybersecurity: Deploying Machine Learning for Network Traffic Anomaly Detection
Abstract: The growing sophistication of cyberattacks and the growth of network traffic necessitate sophisticated anomaly detection methods. This study overviews the use of artificial intelligence (AI) and machine learning (ML) to counter these challenges, as noted in current studies. It analyses supervised learning (SVM, Decision Trees), unsupervised learning (K-means, DBSCAN), and deep learning (CNNs, RNNs, Auto-encoders) approaches, considering their strengths and weaknesses. The research integrates current developments in AI/ML-based network anomaly …
Published in International Journal of Computer Science Languages · Vol. 3, Issue 2, 2025 · pp. 1–10 Read article
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Targeting Homogentisate Dioxygenase Dysfunction in Alkaptonuria: Investigating Curcuma longa’s Therapeutic Potential
Abstract: Objectives: Alkaptonuria is known to have a faulty gene HGO in the metabolic process. In the present research work, the focus is towards investigating the therapeutic capabilities of the Curcuma longa upon the faulty Homogentisate dioxygenase gene using ligand-protein binding, which would assist in the corrective tyrosine metabolism. Methods: This study is based on the computational approach using different phytochemicals for evaluation of the potency against the abnormal Homogentisate dioxygenase …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 2, 2024 · pp. 1–11 Read article
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Analyzing and Predicting Academic Behavior from Peer Pressure Indicators Using Machine Learning
Abstract: The academic achievement of a student is determined by their capability, but also by the companions with whom they associate. Friends can have a positive impact on students' motivation for school, and at times friends are distractions leading to a lack of attention on their school assignments. This particular study focuses on the number and quality of companions students associate with and to what extent that could be used as …
Published in International Journal of Education Sciences · Vol. 3, Issue 2, 2026 Read article
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Analyzing and Predicting Academic Behavior from Peer Pressure Indicators Using Machine Learning
Abstract: The academic achievement of a student is determined by their capability, but also by the companions with whom they associate. Friends can have a positive impact on students' motivation for school, and at times friends are distractions leading to a lack of attention on their school assignments. This particular study focuses on the number and quality of companions students associate with and to what extent that could be used as …
Published in International Journal of Education Sciences · Vol. 3, Issue 2, 2026 · pp. 1–7 Read article
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Computer, Animation and Aesthetic Expressions
Abstract: The integration of computers, animation, and aesthetic expressions has revolutionized creative industries, enabling the development of highly immersive and visually engaging content. This interdisciplinary field combines computer science, digital animation techniques, and the principles of visual aesthetics to craft experiences that resonate with audiences on both intellectual and emotional levels. Through advanced algorithms, artificial intelligence, and innovative rendering techniques, modern animation blends technical precision with artistic design to create dynamic …
Published in Journal of Multimedia Technology & Recent Advancements · Vol. 12, Issue 2, 2025 · pp. 01–06 Read article
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Next-generation Operating Systems: AI-driven Autonomy, Quantum Integration, and Edge Computing
Abstract: The rapid evolution of computing paradigms is driving the need for next-generation operating systems that seamlessly integrate artificial intelligence, quantum computing, and edge processing. Traditional operating systems, while efficient for classical computation, lack the necessary capabilities to handle real-time AI-driven decision-making, quantum processing, and decentralized edge networks. This study explores how future operating systems will incorporate AI-driven autonomy to enhance resource management, quantum integration to leverage superior computational power, and …
Published in Journal of Operating Systems Development & Trends · Vol. 12, Issue 1, 2025 · pp. 25–36 Read article
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Comparative Efficacy and Safety of Safinamide and Rasagiline in the Treatment of Parkinson’s Disease: A Meta-Analysis and Systematic Review
Abstract: Background: Recent studies have suggested Rasagiline and Safinamide monotherapy as potential management options for Parkinson’s disease. Parkinson’s disease, a neurological disorder characterized by tremors and movement difficulties, necessitates treatments aimed at managing clinical symptoms. Levodopa remains the primary effective treatment for Parkinson’s disease symptoms; however, its long-term use often leads to motor complications in many patients. Additional therapeutic drugs, such as dopamine agonists and monoamine oxidase B inhibitors, including Safinamide …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 74–91 Read article
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Computational Modeling of Polymer Semiconductors for Electronic Applications
Abstract: Polymer semiconductors have become important materials in modern electronic applications because they combine semiconducting behavior with mechanical flexibility, low-cost processing, and tunable molecular structure. Their growing use in organic field-effect transistors, organic photovoltaics, organic light-emitting diodes, and flexible sensing devices has increased the need for accurate computational approaches that can predict material properties and device performance before experimental fabrication. This paper reviews the major computational modeling techniques used for polymer …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 132–146 Read article
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Shell Scripting and Unix Programming: Foundations and Techniques
Abstract: Shell scripting and Unix programming are essential components of modern computing, enabling users to automate repetitive tasks, manage system operations, and optimize productivity. Unix, known for its robustness and multi-user capabilities, provides a powerful command-line interface (CLI) that allows efficient system interaction. Shell scripting enhances this functionality by enabling users to execute sequences of commands, making automation seamless and reducing manual effort. Different scripting paradigms: imperative, procedural, functional, and event-driven, …
Published in Journal of Advances in Shell Programming · Vol. 12, Issue 1, 2025 · pp. 10–16 Read article
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Corrugated Tube Shell-and-Tube Heat Exchanger Using Epoxy-Based Polymer Composite Coatings for Lightweight and Efficient Thermal Systems
Abstract: Corrugated tube geometries are widely recognized for their ability to enhance heat transfer through boundary layer disruption and secondary flow generation. In this study, a combined experimental and computational investigation is carried out to evaluate the thermo-hydraulic performance of a shell-and-tube heat exchanger incorporating corrugated stainless steel tubes integrated with an epoxy-based polymer composite coating and housed within a mild steel shell. Unlike conventional metallic systems, the present work introduces …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 603–617 Read article