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563 articles for “ADMET lab 2.0” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Molecular Docking of Arjuna Tree Phytocompounds for Ischemic Heart Disease
Abstract: Heart disease is a serious condition that can be caused by several lifestyle changes and sometimes genetic problems. The primary protein component of apolipoprotein is the LDL receptor, which indicates that a reduction in LDL levels can reduce the risk of ischemic heart disease. Apolipoprotein levels are associated with increased levels of ischemic heart disease. Using ADMET analysis, drug likelihood prediction, and molecular docking, this work attempted to find natural …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 42–52 Read article
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Effectiveness of Moist Heat Application on Elderly Orthopedic Clients at Selected Urban Community Area, Bengaluru
Abstract: Pain is a distressing sensory and emotional experience that arises from actual or potential tissue damage. It is a multifaceted phenomenon that extends beyond physical discomfort, encompassing emotional and psychological aspects as well. Individuals who recognize that pain management not only enhances comfort but also accelerates the healing process are more inclined to seek or administer appropriate treatment. In order to educate the elderly orthopedic clients, this study was conducted …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 18–22 Read article
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Development and evaluation of multigrain pasta
Abstract: Pasta is one of the most consumed food among the food products prepared from cereals due to low cost, ease in preparation along with pleasant textural and sensory characteristics. This study was performed to prepare multigrain pasta by utilising the numerous health benefits of wheat, chickpea, kodo and ragi flour. Each ingredient was selected according to unique nutritional attributes which will be incorporated in pasta to make it more nutritious …
Published in International Journal of Nutritions · Vol. 2, Issue 2, 2025 · pp. 34–47 Read article
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Recent Advancements and Current Status of Hydrogen Fuel Cells: Materials, Systems, Applications, and Commercialization Prospects
Abstract: In the transportation, stationary electricity, and industrial sectors, hydrogen fuel cells have become a crucial clean-energy technology that can help achieve worldwide decarbonization. Significant progress has been made in catalyst design, membrane engineering, stack architecture, system optimization, and hydrogen generation pathways throughout the last ten years (2018–2025). Platinum group metal (PGM) loading has been significantly reduced, single-atom and transition-metal-nitrogen-carbon (M-N-C) catalysts for oxygen reduction have been developed (Wu et al., …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 3, Issue 2, 2025 · pp. 6–24 Read article
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Luminodeficit: The Paradox of High Rent and Abandoned Interiors
Abstract: The paradox of high rent and poor daylighting in residential buildings is a pressing issue in urban areas like Port Harcourt, Rivers State, Nigeria. Despite paying premium rents, many residents experience inadequate daylighting, leading to unexpected behavioral outcomes. This study aims to explore the effects of daylight deprivation on residents of high-rent residential buildings in Port Harcourt. It investigates how poor daylighting influences indoor time spent and overall occupant satisfaction, …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 3, Issue 2, 2025 · pp. 1–7 Read article
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Evaluating the Impact of a Video-Assisted Teaching Program on Knowledge and Attitudes About Teenage Pregnancy Prevention Among Fortunetellers Community Women in a Selected Region of Madurai District
Abstract: This research aims to evaluate the efficacy of a video-assisted teaching program in preventing teenage pregnancy, gauge participants' knowledge and attitudes regarding teenage pregnancy prevention, explore the relationship between their knowledge and attitudes, and examine how demographic variables correlate with pre-test knowledge and attitudes. The research hypotheses were formulated to determine their significance. A survey of the literature was done and organized based on studies related to teenage pregnancy. The …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 26–31 Read article
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In Silico Drug Design for Mycobacterium tuberculosis and Development of Host–Pathogen Interaction Network and Molecular Docking Procedures
Abstract: Objective: A leading cause of illness is the contagious disease tuberculosis (TB), this infection with Mycobacterium tuberculosis complex (MTBC) particularly M. tuberculosis and M. africanum, is what causes tuberculosis. Diverse receptor proteins (mycobacterial proteins) with various 3D structures and functions were evaluated to access the multi-domain antimycobacterial action of ligands. The specific receptor proteins PDB ID: 3PTY, PDB ID: 4OW8, PDB ID: 5KWA, and PDB ID: 3ZXR, were opted for …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 1–19 Read article
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Production of Disinfectant Using Aloe Vera (Aloe barbadensis miller) Plant Extracts
Abstract: This research work demonstrates the production of a disinfectant using aloe vera (Aloe barbadensis Miller) as main source of the raw material. The liquid content of the aloe vera was extracted using mechanical and unit operation mechanisms and the obtained raw material was subjected to heating to evaluate the effect of temperature on the characteristics of the physiochemical properties of pH, total ash, crude fat, fibre and protein, total carbohydrate, …
Published in International Journal of Pollution: Prevention & Control · Vol. 1, Issue 1, 2023 · pp. 17–30 Read article
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A Study to Assess the Awareness of the Breast Cancer Screening Among Teacher Training Students in Selected Teacher Training Institutions at Mysuru with the View to Conduct Educational Program
Abstract: Background: Cancer is one of the major causes of death both in developed and developing countries. Breast cancer is defined by the uncontrollable proliferation of cells within the breast, encompassing different forms of cancer that impact the breast tissue. The majority of breast cancer cases manifest as painless lumps, while a smaller percentage may exhibit additional symptoms. Breast cancer is amenable to almost complete care if detected in its early …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 17–31 Read article
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The Effectiveness of Honey Application for Oral Mucositis in Cancer Patients: A Review of Randomized Controlled Trials
Abstract: Background: Oral mucositis (OM) is a prevalent and distressing adverse outcome of cancer therapies, including chemotherapy and radiation therapy. It is an inflammatory ailment that impacts the mucous membrane inside the mouth, tongue, gums, and throat. OM can cause pain, discomfort, difficulty swallowing, and in severe cases, it can lead to infection and delayed cancer treatment. Although there are various treatments available, such as painkillers, anti-inflammatory drugs, and topical anesthetics, …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 32–39 Read article
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A Study to Evaluate the Effectiveness of Planned Teaching Program of Environmental Health Among Community People in Selected Rural Area of Gwalior
Abstract: Context: Environmental health is the subfield of public health that focuses on identifying and altering environmental contributors to illness and injury. The state of the environment in a certain area, especially as it relates to ecological diversity and pollution. The purpose of this research was to evaluate the efficacy of an environmental health education program for the local population. This study follows a quantitative research approach for its methodology. The …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 23–32 Read article
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Bioremediation of TPH in Petroleum HydrocarbonContaminated Clay Soil with an Emerging Nutrient (Solpawa SBR-X TM)
Abstract: This research focuses on the bioremediation of total petroleum hydrocarbons (TPH) in petroleum hydrocarbon contaminated clay soil with an emerging nutrient (Solpawa SBR-XTM). A laboratory experiment was set up and successfully carried out in order to monitor TPH concentration among the various reactors (T1, T2, T3, and T4). This process was monitored for 7 days, 12 days, 22 days, 32 days, 42 days, and 52 days, respectively, for reactors 1, …
Published in International Journal of Pollution: Prevention & Control · Vol. 1, Issue 1, 2023 · pp. 9–16 Read article
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Molecular Docking Study: Targeting mycobacterium leprae ML2640 Protein Using Active Compounds from Coscinium fenestratum
Abstract: Objectives: Leprosy is an infectious disease in skin, peripheral nerve and mucosa of upper airway. Around 70% of this infection is caused by Mycobacterium leprae, which was discovered during1873. Multi drug therapy is used for the treatment, still multiple drug resistance and reactions has been reported among patients. Hence, this work focused on identifying bioactive compounds from Coscinium fenestratum that can target mycobacterium leprae ML2640 protein by in-silico approach. Method: …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 21–33 Read article
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Detection of Pneumonia in COVID-19 Patients Using X-ray Images
Abstract: This study explores the use of chest X-ray image analysis and deep learning methods to identify pneumonia in COVID-19 patients. Due to the pandemic, Proper as well as immediate examination of COVID-19 is now essential for patient care and disease control. This study proposes a novel approach that uses convolutional neural networks (CNNs) to automatically predict pneumonia in COVID-19 patients using chest X-ray images. In this study, an X-ray of …
Published in International Journal of Radio Frequency Innovations · Vol. 1, Issue 1, 2023 · pp. 13–23 Read article
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Inhibition of PI3K/Akt/mTOR Signaling Pathway by Vitis Vinifera Phytocompounds: A Promising Strategy for Supressing Colorectal Cancer Growth and Metastasis
Abstract: Objectives: Colorectal cancer was not typically identified a few decades ago. Today, with almost 900 000 fatalities each year, it is the fourth most dangerous cancer in the world. Colorectal cancer is responsible for about 10% of all cancer diagnoses annually and cancer-related deaths worldwide. It is the second most common type of cancer in women and the third most common type in men. Incidence and death are roughly 25% …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 64–75 Read article
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A Study to Assess the Effectiveness of Awareness Programme on Knowledge Regarding Health Problems Related to Smart Phone Addiction Among Adolescents Studying in a Selected School, Bangalore, Karnataka
Abstract: Aim: This study assesses the effectiveness of an awareness program on adolescents' knowledge of health problems related to smartphone addiction. Objectives: (1) Evaluate adolescents' understanding of health issues linked to smartphone addiction. (2) Measure the impact of the awareness program on their knowledge by comparing pre-test and post-test scores. (3) Investigate correlations between pre-test knowledge and sociodemographic variables. Method: A quantitative evaluative approach was used. The one-group pre-test post-test research …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 9–13 Read article
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Evaluating the Impact of Information Education and Communication Package on Knowledge and Attitude Regarding Reproductive and Sexual Health among Late Adolescent Girls in Selected Colleges at Madurai
Abstract: A quasi-experimental study was carried out to assess the effectiveness of an Information, Education, and Communication (IEC) package on the knowledge and attitudes related to reproductive and sexual health among late adolescent girls attending colleges in Madurai. The study aimed to: assess the changes in knowledge and attitudes before and after the intervention in both control and experimental groups, evaluate the effectiveness of the IEC package, investigate the correlation between …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 26–32 Read article
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Evaluating Breast Self-examination Awareness Among Young Adult Women in Vaniyamkulam Panchayat to Create an Educational Booklet
Abstract: Introduction: Breast cancer ranks as the second most prevalent cancer worldwide and stands as the primary cancer type among women, both in developed and developing nations. It is estimated that around 25% of all cancer cases globally are attributed to breast cancer. Notably, there was a significant increase in breast cancer incidence from 2008 to 2012 on a global scale. Methods: The research utilized a quantitative methodology, employing a descriptive …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 23–30 Read article
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Prevalence of Rose Powdery Mildew in Different Districts of Himachal Pradesh, India
Abstract: The present investigation was done in the month of March to June and August to November to survey the powdery mildew infection on commercial greenhouses, nurseries and garden grown roses. Powdery mildew manifests as white to grayish patches of powdery growth on the surfaces of plant organs. Powdery mildew of rose was presented all rose growing areas of districts Bilaspur, Kangra, Mandi, Sirmour, Shimla and Solan during the years 2015 …
Published in International Journal of Fungi · Vol. 1, Issue 1, 2024 · pp. 13–18 Read article
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Exploring Biomedical Innovations in the Formulation and Assessment of Medicated Hard Candy Lozenges Containing Metoclopramide Hydrochloride
Abstract: The objective of this study was to formulate and evaluate metoclopramide hydrochloride medicated lozenges for antiemetic action through buccal absorption by incorporating a polymer. All formulations were developed and assessed for in-vitro drug release, physical appearance, weight variation, thickness, hardness, moisture content, mouth-dissolving time, and drug content. The prepared lozenges exhibited uniformity in weight and thickness. The hardness of all formulations ranged between 7.3–15.50 kg/cm², falling within standard limits. The …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 50–62 Read article