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1953 articles for “phosphoinositol-3-kinase pathway” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Revolutionizing Drug Delivery: Recent Advances in Pharmaceutical Dosage Forms
Abstract: Recent advances in pharmaceutical dosage forms revolutionize drug delivery, prioritizing targeted therapy and patient well-being. Enhanced drug carriers address complex medical challenges, from high-grade gliomas to ocular drug delivery, maximizing therapeutic efficacy while minimizing adverse effects. Traditional dosage forms like tablets and capsules undergo meticulous formulation and manufacturing processes, integrating Quality by Design principles for consistent product quality. Liquid formulations encounter stability challenges, necessitating rigorous stability testing and pH monitoring. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 77–89 Read article
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Multiple Sclerosis: A Brief Overview of the Disease, Its Pharmacotherapy
Abstract: Multiple Sclerosis is an autoimmune disorder mostly affecting individuals aged between 20-40. In this disorder, the optic, vertebral, and central nervous system nerves are primarily impacted. It is a neurological condition that worsens over time and is characterized by inflammation and the breakdown of the sheath that surrounds and shields the nerve fiber. Common symptoms may include muscle weakness, numbness, tingling, fatigue, vertigo, tremor, vision complications, pain, Lhermitte sign, sexual …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 13–18 Read article
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Implementation of Light Weight Carbon Composite Driveshaft for a Light Commercial Vehicle
Abstract: The automotive drive shaft is a crucial component for power and torque transmission in vehicles, with a tubular shape that spins due to engine power. The current drive shaft is made of heavy-duty mild steel, increasing the vehicle's weight and fuel consumption. To reduce the weight, a composite material called carbon fiber was used. Carbon fiber showed better performance in driveshaft operation, and its properties were evaluated using universal testing …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 52–65 Read article
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Structural Analysis of Heavy Vehicle Chassis Using Various Geometries and Materials
Abstract: The present research investigates the significance of the automobile chassis as a crucial section of a vehicle that provides a framework for the body and other parts to rest on. It highlights the need for the chassis to have sufficient bending stiffness for the best handling qualities, as well as enough rigidity to withstand shocks, twists, vibrations, and other loads. The draft and designing model for all the sections (I, …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 9–33 Read article
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Analysis of Thermo-Mechanical Properties in Cement Mortar Using Synthesized Silicate Microencapsulation of Phase Change Materials by Sol-Gel Process
Abstract: This investigation delves into improving building thermal comfort using microencapsulated phase change materials (PCM@SiO2) in cement mortar. The encapsulation process, achieved via a sol-gel method, envelops PCM in a silicate shell Differential Scanning Calorimetry (DSC) and Fourier-Transform Infrared Spectroscopy (FTIR) were used to confirm the thermal properties and integrity of encapsulated PCM, which showed an encapsulation efficiency of 92.7% and a thermal storage capacity of 99.7%. The study involved the …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 152–160 Read article
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Screening and Isolation of Bacterial Isolates for Polyhydroxyalkanoates Production from Oil-Contaminated sites
Abstract: Synthetic polymers are generally manufactured from petroleum and chemical-based sources. These polymers are employed in day-to-day life basic needs which leads to the production of huge number of synthetic polymers that accumulate in nature for thousands of years. There are limitations associated with synthetic polymers apart from their non-biodegradability, non-compatibility their mechanical and physical properties that cannot be easily altered narrows their few applications. PHAs (polyhydroxyalkanoates) are biopolymers that can …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 1, 2024 · pp. 1–6 Read article
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Underdiagnosis of Underlying Migraine in Benign Paroxysmal Positional Vertigo
Abstract: Migraine and vestibular migraine are the primary cause of headache in general population world widely. The prevalence shows that 1 in 10 people have migraine. Majorities of headache causes are undiagnosed properly and usually treated for symptomatic treatment without following correct guidelines. Standard treatment options for migraine include acute relief, lifestyle strategies, alternative remedies, and prophylactic drug. Most patients are managed in primary care using painkiller in many cases without …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 1, 2024 · pp. 11–15 Read article
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Study and Thermal Analysis of a Rectangular Duct with Z-shaped Baffle Using Ansys
Abstract: This project aims to enhance heat transfer in a rectangular duct by utilizing Z-shaped baffles. It involves creating a 3D CAD model using SolidWorks and validating it in ANSYS Fluent 2019 R2. The study focuses on analyzing the effect of baffle arrangement, height, and angle on heat transfer rate. Comparative analysis is conducted between rectangular ducts with a 60° angle and heights of 4 mm, 6 mm, and 8 mm. …
Published in International Journal of Energy and Thermal Applications · Vol. 1, Issue 2, 2023 · pp. 14–30 Read article
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Comparative Study to Assess the Knowledge of Higher Secondary School Students Regarding Career Counselling in Selected Rural and Urban Schools of Kashmir
Abstract: Background: Career counseling assists individuals in choosing appropriate educational and occupational choices and making career options based on future employment demands and requirements. Career counseling comprises a wide variety of professional activities that assist people in overcoming career-related obstacles. Aim: The primary objective of the study was to evaluate the understanding of career counseling among students in chosen rural and urban high schools in Kashmir. Method: This study employed a …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 1, 2024 · pp. 11–18 Read article
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Emotional Abilities Among Undergraduate Students of Health Care Professional and Non-professional Courses
Abstract: Emotional Intelligence (EI) also refers to the ability of an individual to perceive, understand, and manage own emotions and others’ emotions. Research reported that individuals with higher EI have better social skills, management skills and effective communication. Education is the most impacting factor in children as they grow and mature by learning new things from the surroundings and academics which influences EI of an individual. Studies on education and emotional …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 1, 2024 · pp. 19–23 Read article
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Impact of Tool rotating speeds on the Mechanical characteristics of dissimilar friction stir-welded AZ80A-Mg – AA6061-Al joints
Abstract: In this investigation, separate AA6061-Al and AZ80A-Mg alloy plates were effectively joined through stir welding with friction. We looked closely at the weld joints' characteristics, especially their mechanical aspects. In the experiment, here were multiple tool rotating rates (rpm) of 800, 1000, 1200, 1400, and 1600 used. A cylindrical pin-equipped tool featuring a tapered profile was utilized, inserted into the AA6061 alloy plate is offset by 0.5 mm, while maintaining …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 161–168 Read article
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A Comprehensive Review of Ayurvedic Pharmaceutics in Charaka Samhita W.S.R to Chikitsasthana.
Abstract: Charaka Samhita provides insightful information on the holistic approach to well-being by addressing every facet of health, from illness management to preventive measures. It is organized into eight Sthana, and is filled with information on anatomy, physiology, disease etiology, diagnosis, treatment, and health maintenance principles. The term "Charakastu Chikitsite" denotes that Charaka Samhita is the greatest treatise on Ayurvedic therapeutics. Numerous subjects related to diagnosis, treatment planning, and disease management …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 1, 2024 · pp. 14–25 Read article
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Section Cutting in Histopathology: An Update
Abstract: Histopathology is the microscopic examination of tissues to diagnose and study diseases, more significantly the diagnosis of cancer. It plays a pivotal role in modern medicine, serving as the gold standard for definitive diagnosis in a wide range of conditions. Through meticulous analysis of tissue morphology (structure) and cellular characteristics, histopathology provides crucial information for disease classification, staging, and guiding patient management. In the world of histopathology, where microscopic details …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 1, 2024 · pp. 29–34 Read article
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Deformation Behaviour of the Billet and Tooling Design on AA5083 through Equal Channel Angular Pressing With Effect of Back Pressure
Abstract: Equal channel angular pressing is an emerging method applied to subject materials to significant plastic strains while maintaining the original shape of the billet. Researchers have discovered that the level of strain attained through equal channel angular pressing is influenced by factors such as the angle of die, friction conditions, and the implementation of back pressure. These variables significantly impact the microstructure and the irregularity of strain within the billet …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 287–303 Read article
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Freshwater Resources in Delhi: A Decadal Analysis of Land Use Changes
Abstract: The escalating global concern over the pollution of freshwater resources, driven by the amplifying stress and scarcity of freshwater, underscores the significance of this study. The investigation examined the alterations in land use and land cover (LULC) in Delhi, concurrently assessing the coliform count in water sources designated for drinking and other purposes. LANDSAT 7 satellite imagery scrutinized the LULC changes in Delhi over a decade (2011 to 2021) to …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 1, 2024 · pp. 13–22 Read article
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Role Strain Among Male Nursing Students in Selected Nursing Colleges in Mangalore
Abstract: Background: The role is the behavior that is expected out of a person in a particular status. Social standards influence the advantages and responsibility of a status, and roles are performed in accordance with social standards. Role strain is the stress that occurs if they are not able to meet the expected role in their life and are facing inequalities in their profession. Objective: To assess the role strain among …
Published in Journal of Nursing Science & Practice · Vol. 14, Issue 1, 2024 · pp. 6–11 Read article
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Effectiveness of State-level Workshop on Nursing Ethics and Legalities Knowledge Among Nursing Officers at KIMS Hospital Bengaluru
Abstract: Introduction: Over the past decade, nurses' roles have expanded, encompassing expertise, autonomy, and accountability from legal and ethical perspectives. Understanding healthcare legal aspects is crucial for high-quality practice, as nurses deal with human events like birth, death, and suffering. Objective: To evaluate the effectiveness of state-level workshop on nursing ethics and legalities knowledge among nursing officers at KIMS Hospital Bengaluru. Method: The study utilized a quasi-experimental design with a single-group …
Published in Journal of Nursing Science & Practice · Vol. 14, Issue 1, 2024 · pp. 12–16 Read article
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A Descriptive Study to Assess the Knowledge Regarding Sexual Abuse Among Adolescent Girls at Government Senior Secondary School, Shri Goindwal Sahib
Abstract: Introduction: Sexual abuse, also known as molestation, is characterized by one individual engaging in abusive sexual behavior towards another. This can involve the use of force or the exploitation of the other person. Molestation typically denotes a single occurrence of sexual assault, particularly against a young child, while sexual abuse is a term used to describe an ongoing pattern of such assaults. This term encompasses actions by an adult or …
Published in Journal of Nursing Science & Practice · Vol. 14, Issue 1, 2024 · pp. 28–33 Read article
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Wind and Earthquake Mitigation: The Impact of Dampers on Tall Structures
Abstract: This paper provides an in-depth examination of the effects of both earthquake and wind loading on high-rise buildings situated across various terrain categories and seismic zones. The research underscores the critical importance of accounting for lateral loads in the design of reinforced concrete structures, as this consideration is essential for maintaining structural stability and ensuring the safety of occupants. The study focuses on identifying the critical design loads for multistory …
Published in Journal of Structural Engineering and Management · Vol. 11, Issue 2, 2024 · pp. 75–83 Read article
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Biological Synthesis of Silver Nanoparticles Using Hibiscus Sabdariffa Leaf Extract and It’s Antibacterial Sensitivity Assay
Abstract: In this study, AgNO3 was effectively used to synthesize silver nanoparticles. Hibiscus sabdariffa leaf extract was used to promptly and easily synthesize silver nanoparticles. An UV-Visible spectrophotometer showed absorbance peak in range of 300-600 nm. The procedure was found to be easy to follow, quick, least step and safe for the environment. It is non-toxic, and a viable substitute for traditional physical or chemical procedures. At room temperature, silver ions …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 1, 2024 · pp. 08–13 Read article