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622 articles for “potential treatments”
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Role of Epigenetic Mechanisms in Lung Fibrosis: Therapeutic Opportunities and Challenges
Abstract: Lung fibrosis poses a serious risk to one's health since it might result in respiratory failure due to an abnormal accumulation of fibrotic tissue in the lungs. Epigenetic mechanisms, such as histone changes, DNA methylation, and non-coding RNAs, closely control gene expression patterns and cellular processes associated with lung fibrosis. Anomalies in DNA methylation patterns connected to changes in gene expression profiles and disturbances in fibrotic signalling pathways are potential …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 9–20 Read article
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Detection and Classification of Diabetic Retinopathy Using Deep Learning Techniques
Abstract: This project delves into the evaluation of three prominent deep learning architectures Basic CNN, ResNet, and DenseNet for their efficacy in detecting diabetic retinopathy from retinal images. Utilizing a diverse dataset, the study employs standard deep learning frameworks to train and validate each model. The focus extends to exploring the potential benefits of transfer learning on a limited dataset. Evaluation metrics like specificity, sensitivity, and accuracy are employed for a …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 64–69 Read article
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Complex Tuberculous Meningitis: A Case Series Highlighting Rare Co-infections and Severe Complications
Abstract: This case series presents two complex cases of tuberculous meningitis (TBM) with different complications, illustrating the diverse clinical presentations and management challenges of this disease. Case 1 involves an 18-year-old female with TBM complicated by cryptococcal co-infection, while Case 2 describes a 64-year-old female with TBM complicated by obstructive hydrocephalus and secondary bacterial infections. Both patients had been on anti-tubercular therapy before presentation. Diagnostic approaches included cerebrospinal fluid analysis, cultures, …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
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Water Hyacinth-Derived Biopolymers as Reinforcements for Sustainable Fiber-Reinforced Polymer Composites
Abstract: Composting has gained significant attention for sustainable waste management and nutrient recycling. This study investigated the efficacy of water hyacinth (Eichhornia crassipes) as a composting material to produce nutrient-rich organic fertilizer. Water hyacinth compost inoculated with nitrogen-fixing (Azotobacter chroococcum) and phosphate-solubilizing bacteria (Pseudomonas putida) exhibited increased nitrogen and phosphorus content compared to uninoculated compost or cattle dung compost. Wheat grown with biofertilizer-enriched water hyacinth compost displayed significantly improved grain yield, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 1012–1017 Read article
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Exploring Azadirachta indica’s Potential to Combat Visceral Leishmaniasis Through GP63 Inhibition
Abstract: Objectives: Millions of people worldwide suffer from the parasite disease visceral leishmaniasis. Determine the naturally occurring active ingredients in Azadirachta indica, which are employed as a disease-prevention agent and have several uses in medicine. To choose the best ligand to use as a medication, absorption, distribution, metabolism, and excretion (ADME) studies and molecular docking are employed. Methods: To obtain the GP63 protein, the Protein Data Bank (PDB) database was accessed. …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 1–12 Read article
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From Concept to Clinical Practice: A Detailed Review of Total Artificial Heart Devices
Abstract: Total artificial heart (TAH) devices are mechanical systems designed to take over the role of a failing heart in patients with severe heart failure. Unlike ventricular assistance devices (VADs), which only support one side of the heart, TAHs replace both ventricles, providing a possible solution for patients who cannot receive a heart transplant. Over time, TAH technology has evolved with a focus on improving biocompatibility, reducing complications related to the …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 1, 2025 · pp. 1–4 Read article
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Integrating Network Pharmacology And Molecular Docking To Investigate The Possibility Of Rutin Against Gout
Abstract: Objective: Gout is an arthritic condition resulting from the deposition of monosodium urate crystals in and around the joints. Rutin, a bioflavanoid or a plant pigment that is mainly found in vegetables and fruits.It is widely known for its anti-inflammatory and antioxidant activity.Hence this research paper proposes the use of an integrated approach of network pharmacology and molecular docking to investigate the potential of Rutin as a treatment option for …
Published in Research and Reviews : Journal of Computational Biology · Vol. 11, Issue 03, 2022 · pp. 14–27 Read article
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A Literature Review on Future Perspective of Metformin use for Chemotherapy
Abstract: The emergence of metformin as a potential anticancer and cancer-preventive therapeutic tool is exciting. More recently, metformin has been associated with decreased cancer incidence and mortality in diabetic patients and the insulin-lowering effects of metformin are integral to its anticancer properties. With the added benefits of being readily available, economical, and easily tolerated with good safety profile, it can be effortlessly transitioned from bench to bedside for cancer therapy. So, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 3, 2020 · pp. 1–9 Read article
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Bacteriophages- A New Frontier in Medicine
Abstract: Bacteriophages, or phages, are viruses that specifically target and infect bacteria, offering an innovative alternative to traditional antibiotic treatments, especially in the face of rising antibiotic resistance. The resurgence of phage therapy has been driven by the increasing prevalence of multidrug-resistant bacterial strains and the slowdown in the development of new antibiotics. Phages, unlike antibiotics, target specific bacterial strains, reducing the impact on the natural microbiota and potentially offering a …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 31–35 Read article
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A Comparative Study of Inorganic and Natural Coagulants for Dairy Wastewater Treatment using Alum Sulphate and Moringa Oleifera
Abstract: The treatment of dairy wastewater is essential to reduce its environmental impact, particularly in terms of organic load and suspended solids. This study investigates the application of alum sulphate as an inorganic coagulant for dairy wastewater treatment and compares its effectiveness with the natural coagulant Moringa oleifera. The performance of both coagulants was evaluated based on key water quality parameters, including pH, Biochemical Oxygen Demand (BOD), Total Suspended Solids (TSS), …
Published in International Journal of Pollution: Prevention & Control · Vol. 3, Issue 1, 2025 · pp. 01–07 Read article
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Some Plant Extracts Potential in Cleaning Soil Environment Contaminated with Petroleum Hydrocarbon
Abstract: This research considered the trend of some agro-based plant extracts obtained from paw paw, mango and aloe-vera leaves for the purpose of treatment of a contaminated soil environment. The potential of each agro-based plant extract was tested with respect to its ability in the area of petroleum hydrocarbon clean-up in soil environment. The impact of the variation on the pH on each of the bioreactor set-up was monitored and the …
Published in Journal of Petroleum Engineering & Technology · Vol. 16, Issue 2, 2026 · pp. 27–39 Read article
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Hypoxic Ischemic Encephalopathy: An Ayurvedic Review and Treatment: A Case Study
Abstract: One of the most severe and potentially fatal conditions of the infant brain that can develop before or during delivery is HIE. Common definitions of HIE include HYPOXIC (insufficient oxygen), ISCHEMIC (insufficient blood flow), and ENCEPHALOPATHY (brain disease). It is a terrible disease that can leave children with severe neurologic deficits or even kill them. HIE happens when a baby's brain receives insufficient oxygen and blood (perinatal hypoxia), which results …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 9, Issue 03, 2022 · pp. 37–42 Read article
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Biomarkers in Cancer Research: Discovery and Future Directions
Abstract: Biomarkers have transformed the study of cancer, providing critical information regarding prognosis and therapy response and promoting earlier diagnosis. This paper discusses the different parts of cancer biomarkers, starting with their description, classification, and major types, which are the groundwork for understanding their clinical role. The discussion on the development and validation process of biomarkers is then undertaken, focusing on state-of-the-art techniques and the importance of ensuring accuracy and reproducibility. …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 22–26 Read article
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Effective Homoeopathic Management of Allergic Rhinitis: A Case Series Utilizing Hepar Sulph 30 and Histamine 30 with Dietary Modifications
Abstract: Background: Allergic rhinitis (AR), means our immune system intruded by some allergens which is typically a harmless substance. These allergens are found in the air we breathe, in the food we eat, in the water and fluids we drink. These allergens are attacking on our immune system and the immune system responds to the allergens by releasing histamine and chemical mediators that cause symptoms in the nose, throat, eyes, ears, …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 11, Issue 2, 2024 · pp. 12–16 Read article
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Solar Light Photocatalytic Degradation of Methylene Blue and Methyl Orange Dyes by Ag-ZnO Nanocomposite
Abstract: A highly efficient silver-assisted ZnO nanocomposite was synthesized using the co-precipitation method, a technique that ensures a controlled and homogeneous formation of the composite material. The high purity of the synthesized nanocomposite was confirmed through detailed FTIR spectra analysis, which showed clear and distinct peaks corresponding to the functional groups present, indicating the absence of significant impurities. To evaluate the photocatalytic capabilities of the nanocomposite, a series of tests were …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 160–171 Read article
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Electrooxidation of Methylene Blue over nanoparticle coated DSA synthesized by sol-gel method
Abstract: The current study uses the sol-gel approach to synthesize a new Dimensionally Stable Anode (DSA) covered with nanoparticles. The objective is to enhance the electrocatalytic activity and overall performance of the anodes in treating synthetic industrial wastewater containing reactive dyes. CuO and TiO2 nanoparticles are coated using a thermal decomposition technique on a titanium electrode. The DSA surface gains more surface area and better catalytic capabilities when nanoparticles are coated …
Published in Emerging Trends in Chemical Engineering · Vol. 11, Issue 2, 2024 · pp. 34–43 Read article
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Nutraceuticals as Adjunctive Treatment in Cancer Exploring Efficacy and Mechanism of Action
Abstract: Dietary habits are a critical factor in cancer prevention, with plant-based diets rich in vegetables and fruits associated with reduced cancer risk. Nutraceuticals—bioactive compounds derived from food and supplements—have gained attention for their potential in cancer prevention and therapy. Phytochemicals such as flavonoids, polyphenols, and alkaloids exhibit anti-cancer properties through mechanisms including antioxidant activity, anti-inflammatory effects, inhibition of tumor growth, and induction of apoptosis. Key nutraceuticals include alkaloids (e.g., caffeine, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 35–45 Read article
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Potential of Mobile Technology (mHealth) in Medical and Health Care Delivery
Abstract: The last decade witnessed an unparalleled growth in the number of mobile phones in the country, thus linking millions of previously unconnected people not only to each other but potentially to the ‘system’ itself. The ubiquity of mobile phones, their ease, affordability and the already existing mobile phone technology and capabilities can be used to provide innovative opportunities for various public health measures. Various studies have already indicated that mobile …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 2, Issue 1, 2013 · pp. 19–24 Read article
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A General Review of Mucuna Pruriens W.S.R to its effect on Parkinson’s Disease.
Abstract: Mucuna Pruriens is a very famous drug prescribed in classical ayurvedic science in various disorder of Nervous System including Kampavata .In Clinical Practice ,Physician used Levadopa as a Dopamine replacement agent in controlling bradykinetic symptoms apparent in Parkinson disease so used successfully in treatment of Parkinson disease.Kapikacchu(Mucuna Pruriens) is having Balya, Brimhanaha, Vrishya, and Vatahara properties and is a natural source of L-dopa. So, keeping in views of the degenerative …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 1, 2024 · pp. 1–6 Read article
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Fungi as Environmental Guardians: Enzymatic Solutions to Pollution
Abstract: Fungi are simple and inexpensive to cultivate, like miniature factories. Their enzymes are more environmentally friendly and safer for all to use compared to the use of dangerous chemicals. This review delves into how scientists are employing these enzymes to clean up polluted soil, purify wastewater, and even convert waste into valuable products such as biofuels.For example, fungi are amazing at cleaning! They create enzymes, which act as little workers …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 Read article