Search
367 articles for “meta-data”
-
Molecular Docking and Interaction of Anthocyanin Derivatives in Regulating Hippo-taz Pathway for Renal Injuries
Abstract: Introduction: The Hippo pathway plays a pivotal role in renal disease, with Yes-associated protein (YAP) exhibiting promise for combined treatments. The crucial evaluation of YAP-targeted drug safety and efficacy through preclinical studies is imperative. Additionally, α-SMA and SMAD3 emerge as potential therapeutic targets in renal fibrosis, driving ongoing research toward innovative interventions. Materials and Methods: In the systematic identification of therapeutic secondary metabolites, Anthocyanin derivatives were methodically retrieved from the …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 23–38 Read article
-
Wear Attribute of Aluminium Metal Matrix Composite Reinforced With MWCNT, Produced By FSP, On A Vertical Milling Machine
Abstract: The exceptional properties of Aluminium metal matrix composites (AMMCs) like good hardness, specific strength, enhanced wear rate made huge demand in the automobile and aerospace industries. The classical methods of manufacturing AMMCs leave problems at the interface of matrix and reinforcement segregation, like an agglomeration of reinforcements, wettability etc. To overcome this, an alternate, innovative method of fabricating aluminium matrix surface composites has been invented, which is termed friction stir …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 525–539 Read article
-
Spectral, thermal, electrochemical and biological studies of Co(II), Ni(II), Cu(II) and Zn(II) complexes derived from 4-(3-bromo-4-hydroxy-5-methoxybenzylideneamino)-3-mercapto-6-methyl-5-oxo-1,2,4-triazine.
Abstract: The Schiff base4-(3-bromo-4-hydroxy-5-methoxybenzylideneamino)-3-mercapto-6-methyl-5-oxo-1,2,4-triazine and its Co(II), Ni(II), Cu(II) and Zn(II) complexes have been synthesized and characterized by IR, NMR, electronic, ESR, fluorescence, thermal, magnetic moment and electrochemical studies. IR and thermal data support the presence of coordinated water in the metal complexes. The electronic spectral and magnetic moment measurements indicate octahedral geometry for Co(II), Ni(II) and Zn(II) complexes and square planar for Cu(II) complexes. Biological studies of the ligand and …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 5, Issue 1, 2014 · pp. 6–16 Read article
-
Comparison of Total Protein Content in the Muscles of Catla catla on Exposure to Ag and ZnO Nanoparticles and their Metal Ions
Abstract: Growing applications of nanotechnology necessitates understanding of nanotoxicity. The toxicity of nanoparticles has gained special attraction amongst various toxicological studies, but restricted data are available on its toxic effects on aquatic organisms. An attempt has been made in present investigation to determine toxicity of NPs of Ag and ZnO and their metal ions to major carp catla. Protein content in muscle tissues of the fingerlings varied with concentration of the …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 7, Issue 3, 2017 · pp. 1–6 Read article
-
New trends in Radio Frequency design and making things smaller
Abstract: Recent improvements in wireless communication, the Internet of Things (IoT), and 5G/6G networks have made people want small, powerful radio frequency (RF) equipment. With an emphasis on how developments in materials engineering, circuit architecture, and packaging technologies are redefining RF system integration, this article offers a thorough evaluation of current developments in RF downsizing. System-on-Chip (SoC), System-in-Package (SiP), and Antenna-in-Package (AiP) ideas, which allow tightly integrated RF front-ends with enhanced …
Published in International Journal of Radio Frequency Innovations · Vol. 3, Issue 2, 2025 · pp. 28–34 Read article
-
Metabolomics: At a Glance
Abstract: Metabolomics is the branch of science which provides the comprehensive analysis of metabolites in a biological system which in turn is useful as a marker. Metabolomics analysis is useful for ascertaining human health conditions. It will provide an insight to cellular metabolism. Since the metabolome directly reflects physiological states, it can biochemically monitor disease states and assess drug actions, improving the preclinical to clinical translation and focusing on predictability, efficiency …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 4, Issue 1, 2017 · pp. 23–30 Read article
-
Meta-Analysis on Antibiotic Resistance and Its Irrational Use in India: Need of Antibiotic Stewardship Program Implementation
Abstract: Antibiotic resistance is a major health issue in developing countries. This issue is increasing exponentially due to increased consumption, easy availability of medicine and higher incidence of inappropriate use. Moreover, India stands as one among the highest infectious disease burdened country in the world. This study aims to conduct a statistical analysis to find the association between antibiotic resistance and its irrational use in India. Thereby, emphasizing the need for …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 6–14 Read article
-
Kenaf Reinforced Polyamide Composite Materials: A Systematic Review
Abstract: Sustainable development has become the global target to prevent exploitation and degradation of our environment in the pursuit for industrial growth. Almost all sectors including engineering, dental, medical, aerospace, etc use synthetic polymers in daily basis. The growing need for sustainable natural alternatives has encouraged research on natural fibres reinforced polymers like kenaf reinforced polyamide composites. Comprehensive evaluation of existing studies is crucial to understand the scope in this field …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 158–169 Read article
-
Synergistic Integration of MEMS and Spintronics for Precision Data Analytics in Cheminformatics
Abstract: The transformational potential of merging spintronics and Micro-Electromechanical Systems (MEMS) technologies in cheminformatics is investigated in this work. Recent advancements in MEMS, particularly through the use of microbeam sensors and accelerometers, enhance the precision of data collection and processing, especially in biomedical applications such as drug delivery systems and chemical sensing. The synchronization of oscillations in MEMS devices leads to improved reliability and data accuracy, enabling the development of sophisticated …
Published in International Journal of Cheminformatics · Vol. 2, Issue 1, 2024 · pp. 20–26 Read article
-
Meta-analysis: An Innovative Tool for Estimating Prevalence of Livestock Diseases
Abstract: AbstractLivestock diseases causes economic loss to the dairy farmers and also affects the productivity of dairy animals. There were no data on prevalence of particular diseases of livestock at state or country level. The prevalence of livestock diseases was required for prioritizing the livestock diseases for taking preventive and control measures with available scarce resources. Meta-analysis is a statistical tool used to combine various studies and estimate the prevalence of …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 9, Issue 1, 2020 · pp. 4–7 Read article
-
Heavy Metals Contamination of Groundwater in Patiala District of Punjab State, India
Abstract: Punjab is facing a crisis situation due to high levels of uranium (U), especially in Malwa belt, along with heavy metals in underground water table of Punjab in selected districts both in Malwa and Majha belts. Department of Water Supply and Sanitation (DWSS), Punjab report on Water Quality Monitoring and Mitigation presents a deplorable situation about the current water quality scenario in Punjab. Nearly 50% habitations are found to be …
Published in Research and Reviews: A Journal of Toxicology · Vol. 9, Issue 3, 2019 · pp. 34–42 Read article
-
A Brief Review on Interfaces of Copper Welded to Different Materials
Abstract: In engineering applications, three metals with high conductivity are primarily used such as copper (Cu), aluminium (Al), and silver (Ag). Each has its unique set of properties that affect specific engineering applications. Infact the choice of conductor depends on a mixture of cost, technical parameters, and environmental conditions. Among these, Copper is widely valued in engineering applications due to its antimicrobial property, excellent electrical (about 100% IACS) and thermal conductivity, …
Published in Trends in Mechanical Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 23–36 Read article
-
Modulation of Receptor Proteins: A Recent Paradigm in Drug Discovery and Target
Abstract: The main aim in drug discovery is to design different ligands those work on specific drug targets. However, various effective drugs work through the modulation of many proteins than single target. Advancement in system biology are establishing a phenotypic strength and a network structure, which suggests that, the excellent selective compounds may be performed less than desired clinical efficacy in comparison to multi-target drugs. In this new appreciation of the …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 1, 2018 · pp. 14–24 Read article
-
Targeting Dystrophin Restoration and Neuroprotection in Duchenne Muscular Dystrophy: Insights from Withania somnifera
Abstract: Duchenne muscular dystrophy is a genetic disorder. This disease affects men more common than women. Main objective of the present study was to identify the naturally active phytocompounds from Withania somnifera (Ashwagandha). Ashwagandha has a great value in the field of Ayurveda and Indian medicine and is used for treating muscular and neurological disorders. Toxicity prediction, molecular docking, statistical information, drug illness prediction, and Absorption, distribution, metabolism, excretion, and toxicity …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 64–84 Read article
-
Extracting and Reducing the linguistics info Content of Web Documents to Support linguistics Document Retrieval
Abstract: Ranking and optimisation of net service compositions represent difficult areas of analysis with significant implication for realization of the “Web of Services” vision. The linguistics net, wherever the linguistics information is indicated mistreatment machine-process ready language like the net metaphysics Language (OWL) “ Semantic net service” use formal linguistics description of web service practicality and alter machine-controlled reasoning over net service compositions. These linguistics net services will then be mechanically …
Published in Journal of Web Engineering & Technology · Vol. 2, Issue 1, 2015 · pp. 10–18 Read article
-
In Silico Analysis and Docking Study of the Active Phytocompounds of Bacopa monnieri Against Alzheimer Disease
Abstract: Objective: Alzheimer’s is a neurodegenerative disease and is the cause of 60–70% of cases of dementia. It infected a million people worldwide. An effort was undertaken to explore the potential of natural compounds found in Bacopa monnieri, a plant renowned for its extensive medicinal properties in Indian Ayurveda, to combat the disease. This was achieved through molecular docking studies, evaluation of drug-likeness, and comprehensive ADME (absorption, distribution, metabolism, and excretion) …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 2, 2024 · pp. 1–13 Read article
-
Past, Present and Future of FNB Mould System
Abstract: This review paper is dealing types of binders used in foundry industries. The different binders have advantages and limitations. This paper gives direction on selection of binder system in different metals. This mainly focuses on selection, advantages and limitations in motor body castings. The data was collected from Krislur Castomech Pvt. Ltd., Chitra G.I.D.C., Bhavnagar. The binder system improves productivity of foundry industries by reducing process cycle time. FNB system …
Published in Journal of Materials & Metallurgical Engineering · Vol. 8, Issue 1, 2018 · pp. 10–16 Read article
-
Triple Negative Breast Cancer—Pattern of Recurrence and Survival: A Single Institute Experience
Abstract: Triple negative breast cancer (TNBC) is a distinct biological entity and recent data shows it as a heterogeneous group with at least 6 subtypes with differences in clinical outcome.This study intends to analyze the prevalence, recurrence pattern and outcome of triple negative breast cancer in our patient cohort.We reviewed the outcomes of 244 consecutive triple negative non-metastatic breast cancer patients who were treated with a radical intent from Jan 2004 …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 6, Issue 3, 2017 · pp. 5–8 Read article
-
Progression in multi-omics and immunological research on host-parasite interactions: Transcriptomics, proteomics, genomics, metabolomics, and immune responses
Abstract: The interaction occuring between hosts and parasites is a quick and multi step-complex biological process that tries to influence disease outcomes. In recent years, multi-omics approaches, such as transcriptomics, proteomics, genomics, metabolomics, and immunological studies, have gathered substantial eye in dissecting these interactions at a microscopic level. These techniques enable a vast understanding of the molecular structures involved in parasitic infections and host defense mechanisms. This article reviews the advancements …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 1–6 Read article
-
Potential Role of Unani Herbs in Management of Hypertensive Cardiomyopathy: A Review
Abstract: AbstractHypertensive cardiomyopathy (HTN-CM) is a structural heart disease associated with concentric left ventricular hypertrophy (LVH) along with systolic or diastolic dysfunction in primary hypertensive patients in the absence of other cardiac diseases causing myocardial hypertrophy or cardiac dysfunction. The structural and functional myocardial abnormalities due to persistent hypertension result in myocardial ischemia, fibrosis, and hypertrophy. HTN-CM is primarily a disease of impaired ventricular relaxation rather than impaired contractility; thus patients …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 7, Issue 1, 2020 · pp. 1–6 Read article