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125 articles for “drugs”
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Nutraceutics: Opening the Debate for a Framework for the Safety and Efficacy of Nutraceuticals Formulations
Abstract: As of right now, there is no precise definition for nutraceuticals that distinguishes them from other food-based categories such herbal products, dietary supplements, pre- and probiotics, functional foods, and fortified foods. Several studies have shed light on the possible mechanisms of action of pharmaceutically active ingredients in food, emphasizing their ability to improve health, lower the risk of disease, and promote general wellbeing. However, Nutraceuticals confront difficulties in substantiating safety …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 1, 2024 · pp. 27–33 Read article
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Grid based docking study of some 2-(4-methylsulfonyl phenyl) pyrimidine derivatives (designed after QSAR studies) with Cyclooxygenase
Abstract: Molecular docking helps in studying drug/ligand or receptor/ protein interactions by identifying the suitable active sites in protein, obtaining the best geometry of ligand-receptor complex and calculating the energy of interaction for different ligands to design more effective ligands. In Grid based docking, after unique conformers of the ligand are generated, the receptor cavity of interest is chosen and a grid is generated around the cavity. Cavity points are found …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 23–41 Read article
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Overview of Virulence Factor of Staphylococcus sp.
Abstract: Staphylococcus is a highly virulent genus of bacteria that can cause a range of infections in humans and animals. The production of toxins, enzymes, and biofilms contributes to its ability to establish infections and evade host defenses. Understanding the characteristics and virulence factors of Staphylococcus is crucial for the development of effective prevention strategies and treatment options. Staphylococcus aureus is a significant etiological agent of nosocomial infections on a global …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 1, 2024 · pp. 25–31 Read article
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Role of W.A.R. Score in Predicting Wound Infection
Abstract: In clinical practice, chronic wounds are a major difficulty that are frequently made worse by the infection risk. However, the lack of precise standards for evaluating the risk of infection and establishing the need for and length of time for systemic antibiotics leads to the overuse and abuse of these drugs, which increases the risk of side effects and the development of antibiotic resistance. To close this gap, the development …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 33–38 Read article
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Horizon Scanning and Early Assessment of Health Technologies for the Treatment of Orphan Diseases
Abstract: The theoretical foundations and regulatory framework of the processes of the formation of an effective health technology assessment (HTA) system at the early stages of the life cycle of medicines are analyzed in the article. Particular attention is paid to horizon scanning (HS) and early assessment of expensive innovative drugs utilized for treating rare diseases. In order to inform policymakers, purchasers, and providers (to prioritize MT research, financial, and operational …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 32–39 Read article
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Cognitive Emotional Regulation Strategies and Locus of Control among Substance Users
Abstract: Substance use is among the major health concern that creates significant disability in a person's mood and behavior, which leads to poor health and loss of productivity. Increasing substance use is associated with various short and long-term effects which affect how they deal with stress, regulate their emotions, decision making, and overall quality of life. The current research aims to Examine relationship between cognitive emotional regulation strategies and locus of …
Published in International Journal of Behavioral Sciences · Vol. 1, Issue 2, 2024 · pp. 01–09 Read article
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Environmental Impact of Ghaf Tree (Prosopis cineraria) on Heavy Metals Concentration in Atmosphere
Abstract: The Ghaf is a hardy tree, drought-resistant, and can grow up to ten meters in height, it tree produces small, yellow flowers which attractive to many habitats, like bees, insects, and birds. The leaves and pods of the Ghaf tree have significant antioxidant and anti-inflammatory properties and can be used in new drug development. Ghaf trees can adapt to changing environmental conditions and planting Ghaf trees could be an effective …
Published in International Journal of Minerals · Vol. 1, Issue 1, 2024 · pp. 1–7 Read article
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Assessment of exacerbation of Depression in pulmonary tuberculosis patients by using PHQ-9 scale at Tertiary Care Hospital
Abstract: Context: Depression leads to more dysfunction and stress, which could affect the patient's life condition. Tuberculosis is a leading cause of comorbidity with depression. Those suffering from tuberculosis and depression are at higher risk of bad health-seeking nature, resulting in higher morbidities, drug resistance, and mortality. The relationship is not well established. Aims: To identify multiple variables/ dependent factors affecting depression respectively in tuberculosis patients and check the medication adherence …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 24–31 Read article
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Formulation and Evaluation of herbal multipurpose cream
Abstract: Multipurpose creams are semi-solid preparations used to lower the risk of skin disorders and fight wrinkles. The primary goal of the research is to produce multipurpose creams utilizing various herbs and then analyze their efficacy. The herbs utilized in the preparations include dried bael leaf powder, amla powder, neem powder and bael leaves. The article emphasizes the importance of topical drug delivery systems in dermatology, highlighting the benefits of delivering …
Published in Recent Trends in Cosmetics · Vol. 1, Issue 2, 2024 · pp. 44–57 Read article
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Heterocyclic Substituted Flavones: Bridging Natural Products and Medicinal Chemistry
Abstract: Heterocyclic substituted flavones represent a unique and promising class of flavonoid derivatives, gaining significant attention in recent years due to their diverse and enhanced biological activities. These compounds are characterized by the incorporation of heterocyclic moieties such as quinoline, pyridine, thiazole, imidazole, oxazole, and pyrazole into the flavone structure, which significantly alters and often enhances their bioactive properties. This structural modification has made heterocyclic flavones particularly appealing as candidates for …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 23–30 Read article
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Practical studies in Vero cell and Human amnion cells for viral and stem cell applications
Abstract: Vero cells are one of the most popular mammalian continuous cells in molecular, cellular, and microbiological research. African green monkey kidneys are used to make these.One continuous cell line is the Vero cell line. This cell line is dependent on anchorage. Vero cells can be cultured in suspension because they are anchorage independent. Thought to be non-tumorigenic cells that came from a female Chlorocebus sabaeus Numerous viruses can infect vero …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 1–8 Read article
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Thalassemia and its management – A review article
Abstract: Thalassemia is a hemoglobinopathy burdening India making it earn title of Thalassemia capital of world. Studying last decade, the overall prevalence worldwide and incidence rates have declined but prevalence rates were high in east and Southeast Asian countries. Screening for carriers and affected individuals and genetic counselling are promising approaches for reducing soaring cases and reducing the further spread. Thalassemia affects various organs due to iron overload and haemolysis leading …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 60–73 Read article
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Intellectual Brilliance: Patents and Copyrights in Publications
Abstract: Intellectual property rights play a vital role in safeguarding creativity and innovation, with copyrights and patents being fundamental tools in this process. This study offers an in-depth exploration of these concepts, focusing on their processes, importance, and practical applications, particularly within the healthcare sector. By delving into the nuances of intellectual property, provides valuable insights into how these rights empower creators and innovators to protect their contributions and further global …
Published in International Journal of Sustainability · Vol. 1, Issue 2, 2024 · pp. 6–11 Read article
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A Review Article on Spice up the Solution of Inflammation Through Phytomedicines
Abstract: Inflammation is a complex, protective immune response essential for healing and combating infection. However, prolonged inflammation is associated with chronic diseases, such as arthritis, cardiovascular disorders, diabetes, and neurodegenerative conditions. Traditional nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids can exhibit adverse effects, particularly with chronic administration. This challenge has encouraged the exploration of natural alternatives. Among various natural anti-inflammatory agents, spices, such as ginger, garlic, turmeric, cardamom, and black pepper have …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 1, 2025 · pp. 1–10 Read article
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The Therapeutic Potential of Nutraceutical in Diabetes Management: A Comprehensive Review
Abstract: Diabetes is a long-term and complex condition characterized by high blood sugar levels resulting from inadequate insulin production, ineffective insulin function, or a combination of both. Various nutraceuticals used in clinical settings have shown beneficial impacts on a range of biochemical and clinical markers related to diabetes. In many traditional medical systems, hypoglycemic agents derived from plants are used to treat, manage, and prevent diabetes mellitus. These plant extracts have …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 1, 2025 · pp. 20–27 Read article
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Unlocking Microbial Potential: Innovations in Natural Product Biosynthesis and Therapeutic Applications
Abstract: MNPs play a pivotal role in diverse fields, spanning medicine, agriculture, and industry. This review paper synthesizes insights from various discussions on microbial natural products, encompassing their sources, bioactive properties, and applications. We explore microbial diversity contributing to natural product synthesis, emphasizing bacteria and fungi as prolific producers. The methods for isolating and characterizing these compounds underscore the interdisciplinary nature of microbial natural product research utilizing various analytical techniques contributing …
Published in International Journal of Fungi · Vol. 2, Issue 1, 2025 · pp. 18–38 Read article
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Quinine: Past, Present, and Future Perspective in Malaria and Autoimmune Disorder
Abstract: Quinine, a natural alkaloid extracted from the bark of the cinchona tree, has traditionally played a key role in treating malaria, a disease caused by parasites of the Plasmodium genus. Since its discovery in the 17th century, quinine has evolved from a rudimentary treatment to an essential component of modern antimalarial therapies. This article explores the historical use of quinine in the fight against malaria, its role in current treatment …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 24–33 Read article
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Rosemary: A Natural Way to Improve Brain Health and Cognitive Function
Abstract: Cognitive decline is a common consequence of aging, often leading to diminished quality of life. Although conventional drug treatments, such as anticholinesterase inhibitors, are available for managing cognitive decline, they are not always effective in older adults and may even induce adverse effects. As a result, there has been growing interest in natural alternatives, particularly traditional herbal medicines, for their potential cognitive-enhancing properties. Among these, Rosmarinus officinalis (Rosemary) has gained …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 30–36 Read article
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Applications of Nanotechnology in Advanced Cosmeceuticals
Abstract: Nanotechnology is the study and manipulation of atoms and molecules on the nanoscale, which is approximately 80,000 times smaller than the width of a human hair. By 2015, the global market for products incorporating nanomaterials is projected to reach $2.6 trillion. This field showcases significant progress in research and development by improving product performance and introducing innovative solutions.The usage of cosmetics has increased significantly throughout time, and they are thought …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 1, 2025 · pp. 8–16 Read article
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Virulence Factors in pathogens :mechanisms of infection & disease progression
Abstract: Pathogens, like bacteria, viruses, fungi, and parasites, have evolved specialized tools – known as virulence factors – that help them infect hosts, escape the immune system, and cause disease. These factors play a key role in determining how severe an infection becomes, how quickly it spreads, and how the body responds. Some pathogens use adhesins to stick to host cells, while others produce toxins that damage tissues or disrupt normal …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 6–11 Read article