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288 articles for “Survival”
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Molecular Docking Studies of Wildtype P53 with Damnacanthal and Scopoletin- Phytochemicals Derived from Morinda Citrifolia
Abstract: Cancer is a prominent cause of mortality globally, and it has the potential to impact any region of the body. The tumor suppressor protein P53 plays a significant role in inhibiting tumor growth by regulating DNA repair, inducing cell cycle arrest, promoting senescence, and triggering apoptosis when confronted with genotoxic stress. P53 is found mutated in 50% of cancers where it loses its tumor suppressive properties and gains oncogenic properties …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 20–31 Read article
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Molecular Docking Study: Targeting mycobacterium leprae ML2640 Protein Using Active Compounds from Coscinium fenestratum
Abstract: Objectives: Leprosy is an infectious disease in skin, peripheral nerve and mucosa of upper airway. Around 70% of this infection is caused by Mycobacterium leprae, which was discovered during1873. Multi drug therapy is used for the treatment, still multiple drug resistance and reactions has been reported among patients. Hence, this work focused on identifying bioactive compounds from Coscinium fenestratum that can target mycobacterium leprae ML2640 protein by in-silico approach. Method: …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 21–33 Read article
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Inhibition of PI3K/Akt/mTOR Signaling Pathway by Vitis Vinifera Phytocompounds: A Promising Strategy for Supressing Colorectal Cancer Growth and Metastasis
Abstract: Objectives: Colorectal cancer was not typically identified a few decades ago. Today, with almost 900 000 fatalities each year, it is the fourth most dangerous cancer in the world. Colorectal cancer is responsible for about 10% of all cancer diagnoses annually and cancer-related deaths worldwide. It is the second most common type of cancer in women and the third most common type in men. Incidence and death are roughly 25% …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 64–75 Read article
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Smart Card Based Lineman Safety
Abstract: As maintenance workers and electrical substations are being repaired, there are more electrical mishaps involving linemen today. Contact with overheated wires is the most frequent reason for electric shock and electrocution in the workplace, but there are other factors as well. When transporting equipment like poles and ladders, this happens when people underestimate the height of the ground and overhead wires. Not separating electrical supply is another common cause of …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 1, Issue 1, 2023 · pp. 1–7 Read article
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Evaluating Epidemiological and Physical Risk Factors in the Development of Chemotherapy-induced Peripheral Neuropathy (CIPN): An In-depth Systematic Review and Meta-analysis
Abstract: Background of study: Chemotherapy-induced peripheral neuropathy (CIPN) encompasses a range of adverse effects caused by various cytotoxic medications and stands as a primary source of pain among individuals who have survived cancer. In instances of pronounced and sudden CIPN, it might become necessary to diminish chemotherapy dosages or discontinue their application. Currently, no efficacious strategy exists for proactively preventing CIPN, managing established chronic CIPN is constrained, and the risk factors …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 10–21 Read article
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Oral Self-examination: An Approach for Early Recognition of Oral Cancer Among Factory Workers: An Experimental Study
Abstract: Background: Cancer is a worldwide concern and ranks among the most dreaded illnesses across the globe. Oral cancers are one common cancer among all cancers. Objectives: To measure the existing knowledge concerning oral self-examination for timely recognition of oral cancer among factory workers and to develop and administer a planned health education programme of oral self-examination for early recognition of oral cancer among factory workers. 40 factory workers were selected …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 22–26 Read article
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A Comprehensive Review On Panic Disorders
Abstract: Panic disorder is a prevalent mental health condition characterized by sudden, recurring episodes of intense fear accompanied by physical symptoms. It is twice as likely to affect women and may have a genetic predisposition. This disorder stems from an exaggerated response of the body's survival mechanisms and hormones, impacting manifestations like agoraphobia. Additionally, it is associated with significant psychiatric comorbidity and impaired functioning in various roles. Recent research has delved …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 1, 2024 · pp. 53–59 Read article
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Benefits of Use of Microalgae in Spacecraft
Abstract: In this time of modern science and technology, we need sustainable development, so that we can meet the demand of future generations as well as the present generation. For this reason, scientists are trying to develop such products which have a considerable remark on every research. Consuming algae as a human food became popular over 70 years after it was discovered in 1942. This concept was first implemented in spacecraft …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 08–12 Read article
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Impact of Built Shape, Forms and Spaces on Human Psychology
Abstract: Shelter is the essential component for human survival, yet they know more about the effects of environmental conditions on human health than they know about how a building’s geometry affects the human brain. Typically, architects work on geometry to integrate the appearance of structures, but design-oriented geometry ignores human experience with respect to psychology and emotion. The psychological effects of architectural geometry on human senses, behaviors, and experiences are the …
Published in International Journal of Architectural Design and Planning · Vol. 2, Issue 1, 2024 · pp. 09–17 Read article
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Aureobasidium pullulans- The Versatile Microcolonial Fungus for Industrial Production of Natural Products
Abstract: Aureobasidium pullulans, a yeast-like fungus, exhibits a remarkable capacity for synthesizing an extensive array of bioproducts with diverse industrial applications. This fungus is known to survive in several environmental conditions, making it a robust organism for biotechnological processes. The organism is characterized by its adaptability to various environmental conditions and habitats. It produces an array of extracellular enzymes such as amylases, lipases, proteases, and pectinases, contributing to its role as …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 1, 2024 · pp. 19–31 Read article
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Marital Rape: Legal And Social Perspective
Abstract: Worldwide, marital rape continues to be a prevalent form of sexual assault and domestic violence, defying growing international condemnation and awareness. Feminist ideologies serve as the foundation for this pervasive affliction, which rips apart victims' trust and stifles their relationships. Gender inequality continues to be prevalent in India, a country where societal norms and legal frameworks frequently fall behind. As opposed to popular belief, matrimony does not confer authorization to …
Published in Recent Trends in Social Studies · Vol. 1, Issue 1, 2024 · pp. 13–16 Read article
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Organometallic Osmium Compounds in Cancer Therapy
Abstract: The exploration of organometallic complexes with osmium as potential anticancer agents was indeed an area of ongoing research. These complexes were being investigated for their unique properties and mechanisms of action against cancer cells. However, it’s essential to note that the field of scientific research is dynamic, and new findings may have emerged since then. Organometallic complexes with osmium can be designed to exhibit specific features that make them promising …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 2, 2023 · pp. 01–25 Read article
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Optimizing Heart Disease Prediction: Comparative Analysis of Machine Learning Algorithm for Early Detection
Abstract: The expanding realm of data analysis holds considerable importance in healthcare, particularly in the medical sector where forecasting heart disease is considered a complex endeavor. Early prediction of serious health conditions can be the determining factor between survival and fatality, with heart disease being one such critical health issue. Over the past decade, the main reason for death has been heart disease. Heart disorders come in many different forms, and …
Published in International Journal of Computer Science Languages · Vol. 2, Issue 1, 2024 · pp. 1–10 Read article
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VALIDATION OF WATERSHED MANAGEMENT PLAN AT TARADGAON REGION USING GEOPHYSICAL & GIS TECHNIQUES
Abstract: Water is an essential requirement for the survival of the living organisms on earth planet. Though it seems to be available in sufficient amount, unfortunately its distribution in space and time is highly scattered. Therefore, water resources management practices should be identified using the spatial data set collected through remote sensing and other tools for its optimistic usage and exploration. This study investigates the utilization of Geophysical and GIS Techniques …
Published in Journal of Water Resource Engineering and Management · Vol. 11, Issue 1, 2024 · pp. 1–7 Read article
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Chompound contaning oxadiazole derivatives and their potential therapeutic uses.
Abstract: Derivatives of oxadiazole or furadi azole rings constitute a significant class of heterocyclic substances. Oxadiazole is a heterocyclic, five-membered ring with two carbons, one oxygen atom, two nitrogen atoms, and two double bonds. They are produced by substituting two nitrogen (-N =) atoms for two methylene groups (= CH) in furan. The furan ring's aromaticity was significantly decreased by substituting these groups, resulting in a conjugated diene character. There were …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 1, 2024 · pp. 68–74 Read article
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A Narrative Review on Osteogenesis Imperfecta and Its Management
Abstract: Osteogenesis imperfecta (OI), sometimes referred to as brittle bone disease, is a heterogeneous illness characterized by short stature, several fractures, and distorted bones. The main contributing factor to OI is mutations in the genes needed to produce type 1 collagen. While severe OI is perinatally fatal, mild OI can occasionally not be detected until maturity. The frequency of Osteogenesis imperfecta ranges from about 1:15,000 to 1:20,000 births. Five kinds of …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 1–10 Read article
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Pharmacological Review On Enzalutamide
Abstract: A key therapeutic option in the treatment of prostate cancer, especially metastatic castration-resistant prostate cancer (mCRPC), is Enzalutamide, a second-generation anti androgen drug. Enzalutamide, discovered by Charles Sawyer and Michael Jung at the University of California, Los Angeles, was developed and Food and Drug Administration (FDA)-approved in 2012. Its therapeutic significance was further solidified with subsequent extensions in indications to encompass metastatic castration-sensitive prostate cancer and non-metastatic castration-resistant prostate cancer. …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 7–15 Read article
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Development of Hybrid Detection and Alert mechanism for Women Safety using AI
Abstract: The integration of AI-based smart surveillance systems in enhancing women's safety and security has been a focal point of research and development. This literature study explores the impact of information technology advancements, particularly in the realm of mobile applications, GPS tracking, and social media platforms, on improving women's safety. Noteworthy contributions include the development of apps such as Circle of 6 and Be Safe, which offer women immediate access to …
Published in Journal of Remote Sensing & GIS · Vol. 15, Issue 1, 2024 · pp. 36–46 Read article
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Thermo-mechanical Modeling and Analysis of Heat Exchangers for Enhanced Performance in Renewable Energy Systems
Abstract: A comprehensive review of the thermo-mechanical properties of heat exchangers used in renewable energy facilities is presented in this research study. Heat exchangers are essential components of many renewable energy resources like biomass boilers, geothermal power plants, and solar thermal systems. It is crucial to comprehend their thermo-mechanical behavior in order to maximize efficiency, guarantee dependability, and increase operational lifespan. This work explores the complex interactions between mechanical stresses and …
Published in Journal of Experimental & Applied Mechanics · Vol. 15, Issue 1, 2024 · pp. 13–19 Read article
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Honeybees as pollinators and their conservation: A review
Abstract: Pollination is a critical mechanism for maintaining and conserving biodiversity, with pollinator diversity playing a major role for the enhancement of food security and livelihoods. Pollinators provide the essential service of enabling plants to produce fruits and seeds in our ecosystems. These pollinators come from many groups within the kingdom Animala, including insects, birds, bats and reptiles. Among them, arthropods, especially honey bees, are pivotal In delivering pollination services to …
Published in International Journal of Insects · Vol. 1, Issue 1, 2024 · pp. 7–11 Read article